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Lymph node cancer

MedGen UID:
182690
•Concept ID:
C0948627
•
Neoplastic Process
Synonyms: cancer of lymph node; Lymph Node Cancer; lymph node cancer; Malignant Lymph Node Neoplasm; malignant lymph node neoplasm; malignant neoplasm of lymph node
 
Monarch Initiative: MONDO:0001082

Definition

A primary or metastatic malignant tumor involving the lymph node. Lymphomas and metastatic carcinomas are representative examples. [from NCI]

Professional guidelines

PubMed

Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study.
Ruan X, Huang D, Zhan Y, Huang J, Huang J, Ng AT, Tsu JH, Na R
Elife 2023 Nov 2;12 doi: 10.7554/eLife.86379. PMID: 37917154Free PMC Article
Recent Advances in the Surgical Treatment of Advanced Gastric Cancer: A Review.
Tan Z
Med Sci Monit 2019 May 13;25:3537-3541. doi: 10.12659/MSM.916475. PMID: 31080234Free PMC Article
Penile Cancer: Contemporary Lymph Node Management.
O'Brien JS, Perera M, Manning T, Bozin M, Cabarkapa S, Chen E, Lawrentschuk N
J Urol 2017 Jun;197(6):1387-1395. Epub 2017 Jan 20 doi: 10.1016/j.juro.2017.01.059. PMID: 28115191

Recent clinical studies

Etiology

Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study.
Ruan X, Huang D, Zhan Y, Huang J, Huang J, Ng AT, Tsu JH, Na R
Elife 2023 Nov 2;12 doi: 10.7554/eLife.86379. PMID: 37917154Free PMC Article
Comprehensive analysis of metastatic gastric cancer tumour cells using single-cell RNA-seq.
Wang B, Zhang Y, Qing T, Xing K, Li J, Zhen T, Zhu S, Zhan X
Sci Rep 2021 Jan 13;11(1):1141. doi: 10.1038/s41598-020-80881-2. PMID: 33441952Free PMC Article
Voltage-Gated Potassium Channels Kv1.3--Potentially New Molecular Target in Cancer Diagnostics and Therapy.
Teisseyre A, Gąsiorowska J, Michalak K
Adv Clin Exp Med 2015 May-Jun;24(3):517-24. doi: 10.17219/acem/22339. PMID: 26467143
Mechanisms of thrombogenesis in polycythemia vera.
Kroll MH, Michaelis LC, Verstovsek S
Blood Rev 2015 Jul;29(4):215-21. Epub 2014 Dec 13 doi: 10.1016/j.blre.2014.12.002. PMID: 25577686Free PMC Article
Hormones and breast cancer.
Wile AG, DiSaia PJ
Am J Surg 1989 Apr;157(4):438-42. doi: 10.1016/0002-9610(89)90596-5. PMID: 2648885

Diagnosis

Clinically Applicable Pan-Origin Cancer Detection for Lymph Nodes via Artificial Intelligence-Based Pathology.
Pan Y, Dai H, Wang S, Wang L, Li Q, Wang W, Li J, Qi D, Yang Z, Jia J, Wang Y, Fang Q, Li L, Zhou W, Song Z, Zou S
Pathobiology 2024;91(5):345-358. Epub 2024 May 8 doi: 10.1159/000539010. PMID: 38718783
Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study.
Ruan X, Huang D, Zhan Y, Huang J, Huang J, Ng AT, Tsu JH, Na R
Elife 2023 Nov 2;12 doi: 10.7554/eLife.86379. PMID: 37917154Free PMC Article
Voltage-Gated Potassium Channels Kv1.3--Potentially New Molecular Target in Cancer Diagnostics and Therapy.
Teisseyre A, Gąsiorowska J, Michalak K
Adv Clin Exp Med 2015 May-Jun;24(3):517-24. doi: 10.17219/acem/22339. PMID: 26467143
Linac-based stereotactic body radiotherapy for oligometastatic patients with single abdominal lymph node recurrent cancer.
Jereczek-Fossa BA, Piperno G, Ronchi S, Catalano G, Fodor C, Cambria R, Fossati Ing P, Gherardi F, Alterio D, Zerini D, Garibaldi C, Baroni G, De Cobelli O, Orecchia R
Am J Clin Oncol 2014 Jun;37(3):227-33. doi: 10.1097/COC.0b013e3182610878. PMID: 22992626
Hormones and breast cancer.
Wile AG, DiSaia PJ
Am J Surg 1989 Apr;157(4):438-42. doi: 10.1016/0002-9610(89)90596-5. PMID: 2648885

Therapy

Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study.
Ruan X, Huang D, Zhan Y, Huang J, Huang J, Ng AT, Tsu JH, Na R
Elife 2023 Nov 2;12 doi: 10.7554/eLife.86379. PMID: 37917154Free PMC Article
Voltage-Gated Potassium Channels Kv1.3--Potentially New Molecular Target in Cancer Diagnostics and Therapy.
Teisseyre A, Gąsiorowska J, Michalak K
Adv Clin Exp Med 2015 May-Jun;24(3):517-24. doi: 10.17219/acem/22339. PMID: 26467143
Linac-based stereotactic body radiotherapy for oligometastatic patients with single abdominal lymph node recurrent cancer.
Jereczek-Fossa BA, Piperno G, Ronchi S, Catalano G, Fodor C, Cambria R, Fossati Ing P, Gherardi F, Alterio D, Zerini D, Garibaldi C, Baroni G, De Cobelli O, Orecchia R
Am J Clin Oncol 2014 Jun;37(3):227-33. doi: 10.1097/COC.0b013e3182610878. PMID: 22992626
Outcomes of cervical lymph node recurrence in patients with esophageal squamous cell carcinoma after esophagectomy with 2-field lymph node dissection.
Lee DH, Kim HR, Kim DK, Park SI, Kim YH
J Thorac Cardiovasc Surg 2013 Aug;146(2):365-71. Epub 2013 Feb 17 doi: 10.1016/j.jtcvs.2013.01.043. PMID: 23422046
Hormones and breast cancer.
Wile AG, DiSaia PJ
Am J Surg 1989 Apr;157(4):438-42. doi: 10.1016/0002-9610(89)90596-5. PMID: 2648885

Prognosis

Clinically Applicable Pan-Origin Cancer Detection for Lymph Nodes via Artificial Intelligence-Based Pathology.
Pan Y, Dai H, Wang S, Wang L, Li Q, Wang W, Li J, Qi D, Yang Z, Jia J, Wang Y, Fang Q, Li L, Zhou W, Song Z, Zou S
Pathobiology 2024;91(5):345-358. Epub 2024 May 8 doi: 10.1159/000539010. PMID: 38718783
Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis.
Ye B, Fan D, Xiong W, Li M, Yuan J, Jiang Q, Zhao Y, Lin J, Liu J, Lv Y, Wang X, Li Z, Su J, Qiao Y
Nat Commun 2021 Jul 22;12(1):4457. doi: 10.1038/s41467-021-24813-2. PMID: 34294701Free PMC Article
Comprehensive analysis of metastatic gastric cancer tumour cells using single-cell RNA-seq.
Wang B, Zhang Y, Qing T, Xing K, Li J, Zhen T, Zhu S, Zhan X
Sci Rep 2021 Jan 13;11(1):1141. doi: 10.1038/s41598-020-80881-2. PMID: 33441952Free PMC Article
Voltage-Gated Potassium Channels Kv1.3--Potentially New Molecular Target in Cancer Diagnostics and Therapy.
Teisseyre A, Gąsiorowska J, Michalak K
Adv Clin Exp Med 2015 May-Jun;24(3):517-24. doi: 10.17219/acem/22339. PMID: 26467143
Hormones and breast cancer.
Wile AG, DiSaia PJ
Am J Surg 1989 Apr;157(4):438-42. doi: 10.1016/0002-9610(89)90596-5. PMID: 2648885

Clinical prediction guides

Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis.
Ye B, Fan D, Xiong W, Li M, Yuan J, Jiang Q, Zhao Y, Lin J, Liu J, Lv Y, Wang X, Li Z, Su J, Qiao Y
Nat Commun 2021 Jul 22;12(1):4457. doi: 10.1038/s41467-021-24813-2. PMID: 34294701Free PMC Article
Formation of Tethers from Spreading Cellular Aggregates.
Beaune G, Winnik FM, Brochard-Wyart F
Langmuir 2015 Dec 1;31(47):12984-92. Epub 2015 Nov 17 doi: 10.1021/acs.langmuir.5b02785. PMID: 26509898
Voltage-Gated Potassium Channels Kv1.3--Potentially New Molecular Target in Cancer Diagnostics and Therapy.
Teisseyre A, Gąsiorowska J, Michalak K
Adv Clin Exp Med 2015 May-Jun;24(3):517-24. doi: 10.17219/acem/22339. PMID: 26467143
Linac-based stereotactic body radiotherapy for oligometastatic patients with single abdominal lymph node recurrent cancer.
Jereczek-Fossa BA, Piperno G, Ronchi S, Catalano G, Fodor C, Cambria R, Fossati Ing P, Gherardi F, Alterio D, Zerini D, Garibaldi C, Baroni G, De Cobelli O, Orecchia R
Am J Clin Oncol 2014 Jun;37(3):227-33. doi: 10.1097/COC.0b013e3182610878. PMID: 22992626
Mucoepidermoid carcinoma of the parotid gland: factors affecting outcome.
Ghosh-Laskar S, Murthy V, Wadasadawala T, Agarwal J, Budrukkar A, Patil N, Kane S, Chaukar D, Pai P, Chaturvedi P, D'Cruz A
Head Neck 2011 Apr;33(4):497-503. doi: 10.1002/hed.21477. PMID: 20629088

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