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Oligoastrocytoma

MedGen UID:
154285
Concept ID:
C0547065
Neoplastic Process
Synonyms: Mixed Oligoastrocytoma; Mixed Oligoastrocytomas; Oligoastrocytoma, Mixed
SNOMED CT: Mixed oligoastrocytoma (716647001); Mixed oligoastrocytoma (253071005)
 
Monarch Initiative: MONDO:0016702
Orphanet: ORPHA251656

Definition

Oligoastrocytoma is a type of low-grade glioma with a mixed astrocytoma and oligodendroglioma histology, manifesting with headaches, speech and motor problems, seizures and, in some, subarachnoid haemorrhage. [from ORDO]

Professional guidelines

PubMed

Levin VA, Ictech SE, Hess KR
CNS Oncol 2018 Apr;7(2):CNS16. Epub 2018 Jan 30 doi: 10.2217/cns-2017-0031. PMID: 29378419Free PMC Article
Le Rhun E, Taillibert S, Chamberlain MC
Expert Rev Neurother 2015 Jun;15(6):601-20. Epub 2015 May 2 doi: 10.1586/14737175.2015.1042455. PMID: 25936680
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732

Recent clinical studies

Etiology

Wesseling P, Capper D
Neuropathol Appl Neurobiol 2018 Feb;44(2):139-150. doi: 10.1111/nan.12432. PMID: 28815663
Buckner JC, Shaw EG, Pugh SL, Chakravarti A, Gilbert MR, Barger GR, Coons S, Ricci P, Bullard D, Brown PD, Stelzer K, Brachman D, Suh JH, Schultz CJ, Bahary JP, Fisher BJ, Kim H, Murtha AD, Bell EH, Won M, Mehta MP, Curran WJ Jr
N Engl J Med 2016 Apr 7;374(14):1344-55. doi: 10.1056/NEJMoa1500925. PMID: 27050206Free PMC Article
Taal W, Bromberg JE, van den Bent MJ
CNS Oncol 2015;4(3):179-92. Epub 2015 Apr 23 doi: 10.2217/cns.15.2. PMID: 25906059Free PMC Article
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmström PO, Collette L, Piérart M, Mirimanoff R, Karim AB; EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council
Lancet 2005 Sep 17-23;366(9490):985-90. doi: 10.1016/S0140-6736(05)67070-5. PMID: 16168780

Diagnosis

Wesseling P, Capper D
Neuropathol Appl Neurobiol 2018 Feb;44(2):139-150. doi: 10.1111/nan.12432. PMID: 28815663
Buckner JC, Shaw EG, Pugh SL, Chakravarti A, Gilbert MR, Barger GR, Coons S, Ricci P, Bullard D, Brown PD, Stelzer K, Brachman D, Suh JH, Schultz CJ, Bahary JP, Fisher BJ, Kim H, Murtha AD, Bell EH, Won M, Mehta MP, Curran WJ Jr
N Engl J Med 2016 Apr 7;374(14):1344-55. doi: 10.1056/NEJMoa1500925. PMID: 27050206Free PMC Article
Taal W, Bromberg JE, van den Bent MJ
CNS Oncol 2015;4(3):179-92. Epub 2015 Apr 23 doi: 10.2217/cns.15.2. PMID: 25906059Free PMC Article
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
van den Bent MJ
Neurol Clin 2007 Nov;25(4):1089-109, ix-x. doi: 10.1016/j.ncl.2007.07.013. PMID: 17964027

Therapy

Baumert BG, Hegi ME, van den Bent MJ, von Deimling A, Gorlia T, Hoang-Xuan K, Brandes AA, Kantor G, Taphoorn MJB, Hassel MB, Hartmann C, Ryan G, Capper D, Kros JM, Kurscheid S, Wick W, Enting R, Reni M, Thiessen B, Dhermain F, Bromberg JE, Feuvret L, Reijneveld JC, Chinot O, Gijtenbeek JMM, Rossiter JP, Dif N, Balana C, Bravo-Marques J, Clement PM, Marosi C, Tzuk-Shina T, Nordal RA, Rees J, Lacombe D, Mason WP, Stupp R
Lancet Oncol 2016 Nov;17(11):1521-1532. Epub 2016 Sep 27 doi: 10.1016/S1470-2045(16)30313-8. PMID: 27686946Free PMC Article
Buckner JC, Shaw EG, Pugh SL, Chakravarti A, Gilbert MR, Barger GR, Coons S, Ricci P, Bullard D, Brown PD, Stelzer K, Brachman D, Suh JH, Schultz CJ, Bahary JP, Fisher BJ, Kim H, Murtha AD, Bell EH, Won M, Mehta MP, Curran WJ Jr
N Engl J Med 2016 Apr 7;374(14):1344-55. doi: 10.1056/NEJMoa1500925. PMID: 27050206Free PMC Article
Taal W, Bromberg JE, van den Bent MJ
CNS Oncol 2015;4(3):179-92. Epub 2015 Apr 23 doi: 10.2217/cns.15.2. PMID: 25906059Free PMC Article
Cairncross G, Wang M, Shaw E, Jenkins R, Brachman D, Buckner J, Fink K, Souhami L, Laperriere N, Curran W, Mehta M
J Clin Oncol 2013 Jan 20;31(3):337-43. Epub 2012 Oct 15 doi: 10.1200/JCO.2012.43.2674. PMID: 23071247Free PMC Article
van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmström PO, Collette L, Piérart M, Mirimanoff R, Karim AB; EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council
Lancet 2005 Sep 17-23;366(9490):985-90. doi: 10.1016/S0140-6736(05)67070-5. PMID: 16168780

Prognosis

Baumert BG, Hegi ME, van den Bent MJ, von Deimling A, Gorlia T, Hoang-Xuan K, Brandes AA, Kantor G, Taphoorn MJB, Hassel MB, Hartmann C, Ryan G, Capper D, Kros JM, Kurscheid S, Wick W, Enting R, Reni M, Thiessen B, Dhermain F, Bromberg JE, Feuvret L, Reijneveld JC, Chinot O, Gijtenbeek JMM, Rossiter JP, Dif N, Balana C, Bravo-Marques J, Clement PM, Marosi C, Tzuk-Shina T, Nordal RA, Rees J, Lacombe D, Mason WP, Stupp R
Lancet Oncol 2016 Nov;17(11):1521-1532. Epub 2016 Sep 27 doi: 10.1016/S1470-2045(16)30313-8. PMID: 27686946Free PMC Article
Zhao H, Yuan M, Yang L, Niu J, Yuan X, Bai Y, Guo L
J Craniofac Surg 2016 May;27(3):e311-3. doi: 10.1097/SCS.0000000000002572. PMID: 27092919
Buckner JC, Shaw EG, Pugh SL, Chakravarti A, Gilbert MR, Barger GR, Coons S, Ricci P, Bullard D, Brown PD, Stelzer K, Brachman D, Suh JH, Schultz CJ, Bahary JP, Fisher BJ, Kim H, Murtha AD, Bell EH, Won M, Mehta MP, Curran WJ Jr
N Engl J Med 2016 Apr 7;374(14):1344-55. doi: 10.1056/NEJMoa1500925. PMID: 27050206Free PMC Article
Omuro A, DeAngelis LM
JAMA 2013 Nov 6;310(17):1842-50. doi: 10.1001/jama.2013.280319. PMID: 24193082
van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmström PO, Collette L, Piérart M, Mirimanoff R, Karim AB; EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council
Lancet 2005 Sep 17-23;366(9490):985-90. doi: 10.1016/S0140-6736(05)67070-5. PMID: 16168780

Clinical prediction guides

Baumert BG, Hegi ME, van den Bent MJ, von Deimling A, Gorlia T, Hoang-Xuan K, Brandes AA, Kantor G, Taphoorn MJB, Hassel MB, Hartmann C, Ryan G, Capper D, Kros JM, Kurscheid S, Wick W, Enting R, Reni M, Thiessen B, Dhermain F, Bromberg JE, Feuvret L, Reijneveld JC, Chinot O, Gijtenbeek JMM, Rossiter JP, Dif N, Balana C, Bravo-Marques J, Clement PM, Marosi C, Tzuk-Shina T, Nordal RA, Rees J, Lacombe D, Mason WP, Stupp R
Lancet Oncol 2016 Nov;17(11):1521-1532. Epub 2016 Sep 27 doi: 10.1016/S1470-2045(16)30313-8. PMID: 27686946Free PMC Article
Buckner JC, Shaw EG, Pugh SL, Chakravarti A, Gilbert MR, Barger GR, Coons S, Ricci P, Bullard D, Brown PD, Stelzer K, Brachman D, Suh JH, Schultz CJ, Bahary JP, Fisher BJ, Kim H, Murtha AD, Bell EH, Won M, Mehta MP, Curran WJ Jr
N Engl J Med 2016 Apr 7;374(14):1344-55. doi: 10.1056/NEJMoa1500925. PMID: 27050206Free PMC Article
Van Den Bent MJ, Bromberg JE, Buckner J
Handb Clin Neurol 2016;134:361-80. doi: 10.1016/B978-0-12-802997-8.00022-0. PMID: 26948366
Cairncross G, Wang M, Shaw E, Jenkins R, Brachman D, Buckner J, Fink K, Souhami L, Laperriere N, Curran W, Mehta M
J Clin Oncol 2013 Jan 20;31(3):337-43. Epub 2012 Oct 15 doi: 10.1200/JCO.2012.43.2674. PMID: 23071247Free PMC Article
van den Bent MJ
Neurol Clin 2007 Nov;25(4):1089-109, ix-x. doi: 10.1016/j.ncl.2007.07.013. PMID: 17964027

Recent systematic reviews

Dhawan S, Patil CG, Chen C, Venteicher AS
Cochrane Database Syst Rev 2020 Jan 20;1(1):CD009229. doi: 10.1002/14651858.CD009229.pub3. PMID: 31958162Free PMC Article
Nahed BV, Redjal N, Brat DJ, Chi AS, Oh K, Batchelor TT, Ryken TC, Kalkanis SN, Olson JJ
J Neurooncol 2015 Dec;125(3):609-30. Epub 2015 Nov 3 doi: 10.1007/s11060-015-1910-2. PMID: 26530264
Sarmiento JM, Venteicher AS, Patil CG
Cochrane Database Syst Rev 2015 Jun 29;6(6):CD009229. doi: 10.1002/14651858.CD009229.pub2. PMID: 26118544Free PMC Article
Zhang L, Wu X, Xu T, Luo C, Qian J, Lu Y
J Cancer Res Clin Oncol 2013 May;139(5):719-26. Epub 2013 Feb 10 doi: 10.1007/s00432-013-1387-3. PMID: 23397358
Perry J, Laperriere N, Zuraw L, Chambers A, Spithoff K, Cairncross JG; Neuro-oncology Disease Site Group; Cancer Care Ontario Program in Evidence-Based Care
Can J Neurol Sci 2007 Nov;34(4):402-10. doi: 10.1017/s0317167100007265. PMID: 18062446

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