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Glioma susceptibility

MedGen UID:
986435
•Concept ID:
CN305335
•
Disease or Syndrome
Synonyms: glioma susceptibility; glioma, susceptibility; glioma, susceptibility to
 
Monarch Initiative: MONDO:0100242
OMIM® Phenotypic series: PS137800

Definition

An inherited susceptibility or predisposition to developing glioma. [from MONDO]

Professional guidelines

PubMed

Serum IgE and Allergy Related Genotypes of IL-4R α and IL-13 Genes: Association with Glioma Susceptibility and Glioblastoma Prognosis.
Gohar MK, Ammar MG, Alnagar AA, Abd-ElAziz HA
Egypt J Immunol 2018 Jan;25(1):19-33. PMID: 30242995
Genotype-based gene signature of glioma risk.
Huang YT, Zhang Y, Wu Z, Michaud DS
Neuro Oncol 2017 Jul 1;19(7):940-950. doi: 10.1093/neuonc/now288. PMID: 28339748Free PMC Article
Association between glutathione S-transferase T1 null genotype and glioma susceptibility: a meta-analysis.
Zhang B, Wang J, Niu H, Li Y, Yuan F, Tian Y, Zhou F, Hao Z, Zheng Y, Li Q, Wang W
Tumour Biol 2014 Mar;35(3):2081-6. doi: 10.1007/s13277-013-1276-z. PMID: 24122206

Recent clinical studies

Etiology

CASC15 Gene Polymorphisms and Glioma Susceptibility in Chinese Children.
Lin HR, Chen YP, Chen HT, Liu XP, Zhou JY, Huang XK, Yuan L, Zhuo ZJ
Curr Med Sci 2022 Aug;42(4):797-802. Epub 2022 Jul 11 doi: 10.1007/s11596-022-2613-5. PMID: 35819658
Role of PVT1 polymorphisms in the glioma susceptibility and prognosis.
Ding X, Zhao Y, Yuan H, Zhang Y, Gao Y
Eur J Cancer Prev 2021 Sep 1;30(5):400-408. doi: 10.1097/CEJ.0000000000000636. PMID: 33443959
Genome-Wide Association Studies in Glioma.
Kinnersley B, Houlston RS, Bondy ML
Cancer Epidemiol Biomarkers Prev 2018 Apr;27(4):418-428. Epub 2018 Jan 30 doi: 10.1158/1055-9965.EPI-17-1080. PMID: 29382702Free PMC Article
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
Melin BS, Barnholtz-Sloan JS, Wrensch MR, Johansen C, Il'yasova D, Kinnersley B, Ostrom QT, Labreche K, Chen Y, Armstrong G, Liu Y, Eckel-Passow JE, Decker PA, Labussière M, Idbaih A, Hoang-Xuan K, Di Stefano AL, Mokhtari K, Delattre JY, Broderick P, Galan P, Gousias K, Schramm J, Schoemaker MJ, Fleming SJ, Herms S, Heilmann S, Nöthen MM, Wichmann HE, Schreiber S, Swerdlow A, Lathrop M, Simon M, Sanson M, Andersson U, Rajaraman P, Chanock S, Linet M, Wang Z, Yeager M; GliomaScan Consortium, Wiencke JK, Hansen H, McCoy L, Rice T, Kosel ML, Sicotte H, Amos CI, Bernstein JL, Davis F, Lachance D, Lau C, Merrell RT, Shildkraut J, Ali-Osman F, Sadetzki S, Scheurer M, Shete S, Lai RK, Claus EB, Olson SH, Jenkins RB, Houlston RS, Bondy ML
Nat Genet 2017 May;49(5):789-794. Epub 2017 Mar 27 doi: 10.1038/ng.3823. PMID: 28346443Free PMC Article
Telomere maintenance and the etiology of adult glioma.
Walsh KM, Wiencke JK, Lachance DH, Wiemels JL, Molinaro AM, Eckel-Passow JE, Jenkins RB, Wrensch MR
Neuro Oncol 2015 Nov;17(11):1445-52. Epub 2015 May 25 doi: 10.1093/neuonc/nov082. PMID: 26014050Free PMC Article

Diagnosis

Association Between LIN28A Gene Polymorphisms and Glioma Susceptibility in Chinese Children.
Guo H, Liao Y, Lin A, Lin H, Huang X, Ruan J, Yuan L, Zhuo Z
Cancer Control 2021 Jan-Dec;28:10732748211040009. doi: 10.1177/10732748211040009. PMID: 34468231Free PMC Article
Role of PVT1 polymorphisms in the glioma susceptibility and prognosis.
Ding X, Zhao Y, Yuan H, Zhang Y, Gao Y
Eur J Cancer Prev 2021 Sep 1;30(5):400-408. doi: 10.1097/CEJ.0000000000000636. PMID: 33443959
XPG gene polymorphisms and glioma susceptibility: a two-centre case-control study.
Yuan L, Hu WM, Chen K, Shi Q, Lin A, Chen HT, Zhuo ZJ, Zeng L
Br J Biomed Sci 2021 Jul;78(3):135-140. Epub 2021 Feb 5 doi: 10.1080/09674845.2020.1870308. PMID: 33393424
Genotype-based gene signature of glioma risk.
Huang YT, Zhang Y, Wu Z, Michaud DS
Neuro Oncol 2017 Jul 1;19(7):940-950. doi: 10.1093/neuonc/now288. PMID: 28339748Free PMC Article
Polymorphisms in DNA Repair Gene and Susceptibility to Glioma: A Systematic Review and Meta-Analysis Based on 33 Studies with 15 SNPs in 9 Genes.
Liu K, Jiang Y
Cell Mol Neurobiol 2017 Mar;37(2):263-274. Epub 2016 Apr 7 doi: 10.1007/s10571-016-0367-y. PMID: 27055523

Therapy

Transcriptome-wide Mendelian randomization study prioritising novel tissue-dependent genes for glioma susceptibility.
Robinson JW, Martin RM, Tsavachidis S, Howell AE, Relton CL, Armstrong GN, Bondy M, Zheng J, Kurian KM
Sci Rep 2021 Jan 27;11(1):2329. doi: 10.1038/s41598-021-82169-5. PMID: 33504897Free PMC Article
Effects of the MAML2 genetic variants in glioma susceptibility and prognosis.
Zhang M, Zhao Y, Zhao J, Huang T, Guo X, Ma X, Wu Y
Biosci Rep 2019 Oct 30;39(10) doi: 10.1042/BSR20192091. PMID: 31652449Free PMC Article
Association of genetic polymorphisms of EGFR with glioma in a Chinese population.
Wang X, Zhang H, Wang D, Li X
Genet Test Mol Biomarkers 2015 Jan;19(1):59-62. doi: 10.1089/gtmb.2014.0228. PMID: 25514356Free PMC Article
Association between ERCC1 C8092A and ERCC2 K751Q polymorphisms and risk of adult glioma: a meta-analysis.
Xu Z, Ma W, Gao L, Xing B
Tumour Biol 2014 Apr;35(4):3211-21. Epub 2013 Nov 20 doi: 10.1007/s13277-013-1420-9. PMID: 24254311
Selected polymorphisms of GSTP1 and TERT were associated with glioma risk in Han Chinese.
Li G, Jin TB, Wei XB, He SM, Liang HJ, Yang HX, Cui Y, Chen C, Cai LB, Gao GD
Cancer Epidemiol 2012 Dec;36(6):525-7. Epub 2012 Jul 12 doi: 10.1016/j.canep.2012.06.008. PMID: 22795327

Prognosis

Role of PVT1 polymorphisms in the glioma susceptibility and prognosis.
Ding X, Zhao Y, Yuan H, Zhang Y, Gao Y
Eur J Cancer Prev 2021 Sep 1;30(5):400-408. doi: 10.1097/CEJ.0000000000000636. PMID: 33443959
XPG gene polymorphisms and glioma susceptibility: a two-centre case-control study.
Yuan L, Hu WM, Chen K, Shi Q, Lin A, Chen HT, Zhuo ZJ, Zeng L
Br J Biomed Sci 2021 Jul;78(3):135-140. Epub 2021 Feb 5 doi: 10.1080/09674845.2020.1870308. PMID: 33393424
The ADCY9 genetic variants are associated with glioma susceptibility and patient prognosis.
Zhang G, Xi M, Li Y, Wang L, Gao L, Zhang L, Yang Z, Shi H
Genomics 2021 Mar;113(2):706-716. Epub 2020 Dec 14 doi: 10.1016/j.ygeno.2020.12.019. PMID: 33326832
Impact of AKAP6 polymorphisms on Glioma susceptibility and prognosis.
Zhang M, Zhao Y, Zhao J, Huang T, Wu Y
BMC Neurol 2019 Nov 23;19(1):296. doi: 10.1186/s12883-019-1504-2. PMID: 31759389Free PMC Article
Telomere maintenance and the etiology of adult glioma.
Walsh KM, Wiencke JK, Lachance DH, Wiemels JL, Molinaro AM, Eckel-Passow JE, Jenkins RB, Wrensch MR
Neuro Oncol 2015 Nov;17(11):1445-52. Epub 2015 May 25 doi: 10.1093/neuonc/nov082. PMID: 26014050Free PMC Article

Clinical prediction guides

Epidemiological characteristics and genetic alterations in adult diffuse glioma in East Asian populations.
Mo Z, Xin J, Chai R, Woo PYM, Chan DTM, Wang J
Cancer Biol Med 2022 Nov 1;19(10):1440-59. doi: 10.20892/j.issn.2095-3941.2022.0418. PMID: 36350002Free PMC Article
CASC15 Gene Polymorphisms and Glioma Susceptibility in Chinese Children.
Lin HR, Chen YP, Chen HT, Liu XP, Zhou JY, Huang XK, Yuan L, Zhuo ZJ
Curr Med Sci 2022 Aug;42(4):797-802. Epub 2022 Jul 11 doi: 10.1007/s11596-022-2613-5. PMID: 35819658
The ADCY9 genetic variants are associated with glioma susceptibility and patient prognosis.
Zhang G, Xi M, Li Y, Wang L, Gao L, Zhang L, Yang Z, Shi H
Genomics 2021 Mar;113(2):706-716. Epub 2020 Dec 14 doi: 10.1016/j.ygeno.2020.12.019. PMID: 33326832
Genotype-based gene signature of glioma risk.
Huang YT, Zhang Y, Wu Z, Michaud DS
Neuro Oncol 2017 Jul 1;19(7):940-950. doi: 10.1093/neuonc/now288. PMID: 28339748Free PMC Article
CXCL12 G801A polymorphism and susceptibility to glioma: a case‑control study.
Chang SF, Li SL, Yang B, Yao KM, Miao RH, Liang GF, Zhang KM
Genet Mol Res 2015 Dec 21;14(4):17399-405. doi: 10.4238/2015.December.21.9. PMID: 26782381

Recent systematic reviews

Association Between LIN28A Gene Polymorphisms and Glioma Susceptibility in Chinese Children.
Guo H, Liao Y, Lin A, Lin H, Huang X, Ruan J, Yuan L, Zhuo Z
Cancer Control 2021 Jan-Dec;28:10732748211040009. doi: 10.1177/10732748211040009. PMID: 34468231Free PMC Article
The genetic polymorphisms of angiotensin converting enzyme insertion/deletion and glioma susceptibility: A meta-analysis.
Sun M, Fang Y, Ma S, Gao X, Sun Y
J Renin Angiotensin Aldosterone Syst 2020 Oct-Dec;21(4):1470320320963939. doi: 10.1177/1470320320963939. PMID: 33045911Free PMC Article
Polymorphisms in DNA Repair Gene and Susceptibility to Glioma: A Systematic Review and Meta-Analysis Based on 33 Studies with 15 SNPs in 9 Genes.
Liu K, Jiang Y
Cell Mol Neurobiol 2017 Mar;37(2):263-274. Epub 2016 Apr 7 doi: 10.1007/s10571-016-0367-y. PMID: 27055523
Systematic review on the association between ERCC1 rs3212986 and ERCC2 rs13181 polymorphisms and glioma risk.
Zhou CX, Zhao JH
Genet Mol Res 2015 Mar 31;14(1):2868-75. doi: 10.4238/2015.March.31.17. PMID: 25867436

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