U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Anterior compartment of tibia syndrome

MedGen UID:
1569
•Concept ID:
C0003152
•
Disease or Syndrome
Synonym: Anterior compartment syndrome
 
Monarch Initiative: MONDO:0006648

Definition

Rapid swelling, increased tension, pain, and ischemic necrosis of the muscles of the anterior tibial compartment of the leg, often following excessive physical exertion. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnterior compartment of tibia syndrome

Professional guidelines

PubMed

Surgical management of exertional anterior compartment syndrome of the leg.
Ali T, Mohammed F, Mencia M, Maharaj D, Hoford R
West Indian Med J 2013 Jul;62(6):529-32. doi: 10.7727/wimj.2006.135. PMID: 24756740
Staged management of high-energy proximal tibia fractures (OTA types 41): the results of a prospective, standardized protocol.
Egol KA, Tejwani NC, Capla EL, Wolinsky PL, Koval KJ
J Orthop Trauma 2005 Aug;19(7):448-55; discussion 456. doi: 10.1097/01.bot.0000171881.11205.80. PMID: 16056075

Recent clinical studies

Etiology

Avoiding Compartment Syndrome, Vascular Injury, and Neurologic Deficit in Tibial Osteotomy: An Observational Study of 108 Limbs.
Hoellwarth JS, Geffner A, Fragomen AT, Reif TJ, Rozbruch SR
J Am Acad Orthop Surg Glob Res Rev 2023 Nov 1;7(11) Epub 2023 Nov 16 doi: 10.5435/JAAOSGlobal-D-23-00075. PMID: 37973030Free PMC Article
Perioperative complications in osteotomies around the knee: a study in 858 cases.
Ferner F, Lutter C, Schubert I, Schenke M, Strecker W, Dickschas J
Arch Orthop Trauma Surg 2022 May;142(5):769-775. Epub 2021 Jan 8 doi: 10.1007/s00402-020-03696-w. PMID: 33417020
Fractures Around the Knee in Children.
Young EY, Shlykov MA, Hosseinzadeh P, Abzug JM, Baldwin KD, Milbrandt TA
Instr Course Lect 2019;68:463-472. PMID: 32032063
Surgical management of exertional anterior compartment syndrome of the leg.
Ali T, Mohammed F, Mencia M, Maharaj D, Hoford R
West Indian Med J 2013 Jul;62(6):529-32. doi: 10.7727/wimj.2006.135. PMID: 24756740
Comparison of tissue oxygenation and compartment pressure following tibia fracture.
Hansen EN, Manzano G, Kandemir U, Mok JM
Injury 2013 Aug;44(8):1076-80. Epub 2012 Dec 21 doi: 10.1016/j.injury.2012.11.012. PMID: 23265784

Diagnosis

Tibial anterior compartment compressibility in healthy subject, measured using compression sonography.
Anwander H, Büchel L, Krause F, Siebenrock K, Schmid T
Injury 2022 Feb;53(2):719-723. Epub 2021 Dec 17 doi: 10.1016/j.injury.2021.12.014. PMID: 34963511
Fractures Around the Knee in Children.
Young EY, Shlykov MA, Hosseinzadeh P, Abzug JM, Baldwin KD, Milbrandt TA
Instr Course Lect 2019;68:463-472. PMID: 32032063
Feasibility of ultrasound measurement in a human model of acute compartment syndrome.
Mühlbacher J, Pauzenberger R, Asenbaum U, Gauster T, Kapral S, Herkner H, Duma A
World J Emerg Surg 2019;14:4. Epub 2019 Feb 4 doi: 10.1186/s13017-019-0222-9. PMID: 30740139Free PMC Article
Overuse injuries in classical ballet.
Khan K, Brown J, Way S, Vass N, Crichton K, Alexander R, Baxter A, Butler M, Wark J
Sports Med 1995 May;19(5):341-57. doi: 10.2165/00007256-199519050-00004. PMID: 7618011
Compartment syndrome and shin splints of the lower leg.
Gerow G, Matthews B, Jahn W, Gerow R
J Manipulative Physiol Ther 1993 May;16(4):245-52. PMID: 8340719

Therapy

Avoiding Compartment Syndrome, Vascular Injury, and Neurologic Deficit in Tibial Osteotomy: An Observational Study of 108 Limbs.
Hoellwarth JS, Geffner A, Fragomen AT, Reif TJ, Rozbruch SR
J Am Acad Orthop Surg Glob Res Rev 2023 Nov 1;7(11) Epub 2023 Nov 16 doi: 10.5435/JAAOSGlobal-D-23-00075. PMID: 37973030Free PMC Article
Perioperative complications in osteotomies around the knee: a study in 858 cases.
Ferner F, Lutter C, Schubert I, Schenke M, Strecker W, Dickschas J
Arch Orthop Trauma Surg 2022 May;142(5):769-775. Epub 2021 Jan 8 doi: 10.1007/s00402-020-03696-w. PMID: 33417020
Intravenous Mannitol reduces intracompartmental pressure following tibia fractures: A randomized controlled trial.
Nesaraj J, Varghese VD, Boopalan PR, Nithyananth M, Sudarsanam TD, Jepegnanam TS
Chin J Traumatol 2021 Mar;24(2):109-112. Epub 2020 Nov 20 doi: 10.1016/j.cjtee.2020.11.006. PMID: 33288404Free PMC Article
Infection and Nonunion After Fasciotomy for Compartment Syndrome Associated With Tibia Fractures: A Matched Cohort Comparison.
Blair JA, Stoops TK, Doarn MC, Kemper D, Erdogan M, Griffing R, Sagi HC
J Orthop Trauma 2016 Jul;30(7):392-6. doi: 10.1097/BOT.0000000000000570. PMID: 26978131
Tibial compartment syndrome complicating closed femoral nailing: diagnosis delayed by an epidural analgesic technique--case report.
Morrow BC, Mawhinney IN, Elliott JR
J Trauma 1994 Nov;37(5):867-8. PMID: 7966494

Prognosis

OTA/AO Classification Is Highly Predictive of Acute Compartment Syndrome After Tibia Fracture: A Cohort of 2885 Fractures.
Beebe MJ, Auston DA, Quade JH, Serrano-Riera R, Shah AR, Watson DT, Sanders RW, Mir HR
J Orthop Trauma 2017 Nov;31(11):600-605. doi: 10.1097/BOT.0000000000000918. PMID: 28614149
Infection and Nonunion After Fasciotomy for Compartment Syndrome Associated With Tibia Fractures: A Matched Cohort Comparison.
Blair JA, Stoops TK, Doarn MC, Kemper D, Erdogan M, Griffing R, Sagi HC
J Orthop Trauma 2016 Jul;30(7):392-6. doi: 10.1097/BOT.0000000000000570. PMID: 26978131
Operatively treated type IV tibial tubercle apophyseal fractures.
Pace JL, McCulloch PC, Momoh EO, Nasreddine AY, Kocher MS
J Pediatr Orthop 2013 Dec;33(8):791-6. doi: 10.1097/BPO.0b013e3182968984. PMID: 23812134
High tibial osteotomy with anterior advancement of distal fragment for medial and patellofemoral compartmental osteoarthritis of the knee.
Saito T, Takeuchi R, Ara Y, Yoshida T, Koshino T
Knee 2002 May;9(2):127-32. doi: 10.1016/s0968-0160(01)00147-8. PMID: 11950576
Weakness of foot dorsiflexion and changes in compartment pressures after tibial osteotomy.
Gibson MJ, Barnes MR, Allen MJ, Chan RN
J Bone Joint Surg Br 1986 May;68(3):471-5. doi: 10.1302/0301-620X.68B3.3733817. PMID: 3733817

Clinical prediction guides

Avoiding Compartment Syndrome, Vascular Injury, and Neurologic Deficit in Tibial Osteotomy: An Observational Study of 108 Limbs.
Hoellwarth JS, Geffner A, Fragomen AT, Reif TJ, Rozbruch SR
J Am Acad Orthop Surg Glob Res Rev 2023 Nov 1;7(11) Epub 2023 Nov 16 doi: 10.5435/JAAOSGlobal-D-23-00075. PMID: 37973030Free PMC Article
Porcine Model of Acute Compartment Syndrome.
Honjol Y, Monk R, Schupbach D, Merle G, Harvey EJ
J Orthop Trauma 2023 Mar 1;37(3):e122-e127. doi: 10.1097/BOT.0000000000002505. PMID: 36219778
Tibial anterior compartment compressibility in healthy subject, measured using compression sonography.
Anwander H, Büchel L, Krause F, Siebenrock K, Schmid T
Injury 2022 Feb;53(2):719-723. Epub 2021 Dec 17 doi: 10.1016/j.injury.2021.12.014. PMID: 34963511
A strategy to prevent complications of hyperextension type tibial plateau fracture.
Lin KC, Tarng YW
Eur J Orthop Surg Traumatol 2021 Jan;31(1):71-78. Epub 2020 Jul 26 doi: 10.1007/s00590-020-02739-7. PMID: 32715326
OTA/AO Classification Is Highly Predictive of Acute Compartment Syndrome After Tibia Fracture: A Cohort of 2885 Fractures.
Beebe MJ, Auston DA, Quade JH, Serrano-Riera R, Shah AR, Watson DT, Sanders RW, Mir HR
J Orthop Trauma 2017 Nov;31(11):600-605. doi: 10.1097/BOT.0000000000000918. PMID: 28614149

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...