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Anterior compartment of tibia syndrome

MedGen UID:
1569
•Concept ID:
C0003152
•
Disease or Syndrome
Synonym: Anterior compartment syndrome
 
Monarch Initiative: MONDO:0006648

Definition

Rapid swelling, increased tension, pain, and ischemic necrosis of the muscles of the anterior tibial compartment of the leg, often following excessive physical exertion. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnterior compartment of tibia syndrome

Professional guidelines

PubMed

Surgical management of exertional anterior compartment syndrome of the leg.
Ali T, Mohammed F, Mencia M, Maharaj D, Hoford R
West Indian Med J 2013 Jul;62(6):529-32. doi: 10.7727/wimj.2006.135. PMID: 24756740
Staged management of high-energy proximal tibia fractures (OTA types 41): the results of a prospective, standardized protocol.
Egol KA, Tejwani NC, Capla EL, Wolinsky PL, Koval KJ
J Orthop Trauma 2005 Aug;19(7):448-55; discussion 456. doi: 10.1097/01.bot.0000171881.11205.80. PMID: 16056075

Recent clinical studies

Etiology

Avoiding Compartment Syndrome, Vascular Injury, and Neurologic Deficit in Tibial Osteotomy: An Observational Study of 108 Limbs.
Hoellwarth JS, Geffner A, Fragomen AT, Reif TJ, Rozbruch SR
J Am Acad Orthop Surg Glob Res Rev 2023 Nov 1;7(11) Epub 2023 Nov 16 doi: 10.5435/JAAOSGlobal-D-23-00075. PMID: 37973030Free PMC Article
Perioperative complications in osteotomies around the knee: a study in 858 cases.
Ferner F, Lutter C, Schubert I, Schenke M, Strecker W, Dickschas J
Arch Orthop Trauma Surg 2022 May;142(5):769-775. Epub 2021 Jan 8 doi: 10.1007/s00402-020-03696-w. PMID: 33417020
Fractures Around the Knee in Children.
Young EY, Shlykov MA, Hosseinzadeh P, Abzug JM, Baldwin KD, Milbrandt TA
Instr Course Lect 2019;68:463-472. PMID: 32032063
Acute Exertional Compartment Syndrome in Young Athletes: A Descriptive Case Series and Review of the Literature.
Livingston KS, Meehan WP 3rd, Hresko MT, Matheney TH, Shore BJ
Pediatr Emerg Care 2018 Feb;34(2):76-80. doi: 10.1097/PEC.0000000000000647. PMID: 27248777
Comparison of tissue oxygenation and compartment pressure following tibia fracture.
Hansen EN, Manzano G, Kandemir U, Mok JM
Injury 2013 Aug;44(8):1076-80. Epub 2012 Dec 21 doi: 10.1016/j.injury.2012.11.012. PMID: 23265784

Diagnosis

Tibial anterior compartment compressibility in healthy subject, measured using compression sonography.
Anwander H, Büchel L, Krause F, Siebenrock K, Schmid T
Injury 2022 Feb;53(2):719-723. Epub 2021 Dec 17 doi: 10.1016/j.injury.2021.12.014. PMID: 34963511
Fractures Around the Knee in Children.
Young EY, Shlykov MA, Hosseinzadeh P, Abzug JM, Baldwin KD, Milbrandt TA
Instr Course Lect 2019;68:463-472. PMID: 32032063
Feasibility of ultrasound measurement in a human model of acute compartment syndrome.
Mühlbacher J, Pauzenberger R, Asenbaum U, Gauster T, Kapral S, Herkner H, Duma A
World J Emerg Surg 2019;14:4. Epub 2019 Feb 4 doi: 10.1186/s13017-019-0222-9. PMID: 30740139Free PMC Article
Comparison of tissue oxygenation and compartment pressure following tibia fracture.
Hansen EN, Manzano G, Kandemir U, Mok JM
Injury 2013 Aug;44(8):1076-80. Epub 2012 Dec 21 doi: 10.1016/j.injury.2012.11.012. PMID: 23265784
Compartment syndrome and shin splints of the lower leg.
Gerow G, Matthews B, Jahn W, Gerow R
J Manipulative Physiol Ther 1993 May;16(4):245-52. PMID: 8340719

Therapy

Avoiding Compartment Syndrome, Vascular Injury, and Neurologic Deficit in Tibial Osteotomy: An Observational Study of 108 Limbs.
Hoellwarth JS, Geffner A, Fragomen AT, Reif TJ, Rozbruch SR
J Am Acad Orthop Surg Glob Res Rev 2023 Nov 1;7(11) Epub 2023 Nov 16 doi: 10.5435/JAAOSGlobal-D-23-00075. PMID: 37973030Free PMC Article
Perioperative complications in osteotomies around the knee: a study in 858 cases.
Ferner F, Lutter C, Schubert I, Schenke M, Strecker W, Dickschas J
Arch Orthop Trauma Surg 2022 May;142(5):769-775. Epub 2021 Jan 8 doi: 10.1007/s00402-020-03696-w. PMID: 33417020
Intravenous Mannitol reduces intracompartmental pressure following tibia fractures: A randomized controlled trial.
Nesaraj J, Varghese VD, Boopalan PR, Nithyananth M, Sudarsanam TD, Jepegnanam TS
Chin J Traumatol 2021 Mar;24(2):109-112. Epub 2020 Nov 20 doi: 10.1016/j.cjtee.2020.11.006. PMID: 33288404Free PMC Article
A strategy to prevent complications of hyperextension type tibial plateau fracture.
Lin KC, Tarng YW
Eur J Orthop Surg Traumatol 2021 Jan;31(1):71-78. Epub 2020 Jul 26 doi: 10.1007/s00590-020-02739-7. PMID: 32715326
Infection and Nonunion After Fasciotomy for Compartment Syndrome Associated With Tibia Fractures: A Matched Cohort Comparison.
Blair JA, Stoops TK, Doarn MC, Kemper D, Erdogan M, Griffing R, Sagi HC
J Orthop Trauma 2016 Jul;30(7):392-6. doi: 10.1097/BOT.0000000000000570. PMID: 26978131

Prognosis

OTA/AO Classification Is Highly Predictive of Acute Compartment Syndrome After Tibia Fracture: A Cohort of 2885 Fractures.
Beebe MJ, Auston DA, Quade JH, Serrano-Riera R, Shah AR, Watson DT, Sanders RW, Mir HR
J Orthop Trauma 2017 Nov;31(11):600-605. doi: 10.1097/BOT.0000000000000918. PMID: 28614149
Infection and Nonunion After Fasciotomy for Compartment Syndrome Associated With Tibia Fractures: A Matched Cohort Comparison.
Blair JA, Stoops TK, Doarn MC, Kemper D, Erdogan M, Griffing R, Sagi HC
J Orthop Trauma 2016 Jul;30(7):392-6. doi: 10.1097/BOT.0000000000000570. PMID: 26978131
Acute compartment syndrome of the foot following fixation of a pilon variant ankle fracture.
Henning A, Gaines RJ, Carr D, Lambert E
Orthopedics 2010 Dec 1;33(12):926. doi: 10.3928/01477447-20101021-33. PMID: 21162493
High tibial osteotomy with anterior advancement of distal fragment for medial and patellofemoral compartmental osteoarthritis of the knee.
Saito T, Takeuchi R, Ara Y, Yoshida T, Koshino T
Knee 2002 May;9(2):127-32. doi: 10.1016/s0968-0160(01)00147-8. PMID: 11950576
Weakness of foot dorsiflexion and changes in compartment pressures after tibial osteotomy.
Gibson MJ, Barnes MR, Allen MJ, Chan RN
J Bone Joint Surg Br 1986 May;68(3):471-5. doi: 10.1302/0301-620X.68B3.3733817. PMID: 3733817

Clinical prediction guides

Avoiding Compartment Syndrome, Vascular Injury, and Neurologic Deficit in Tibial Osteotomy: An Observational Study of 108 Limbs.
Hoellwarth JS, Geffner A, Fragomen AT, Reif TJ, Rozbruch SR
J Am Acad Orthop Surg Glob Res Rev 2023 Nov 1;7(11) Epub 2023 Nov 16 doi: 10.5435/JAAOSGlobal-D-23-00075. PMID: 37973030Free PMC Article
Porcine Model of Acute Compartment Syndrome.
Honjol Y, Monk R, Schupbach D, Merle G, Harvey EJ
J Orthop Trauma 2023 Mar 1;37(3):e122-e127. doi: 10.1097/BOT.0000000000002505. PMID: 36219778
Tibial anterior compartment compressibility in healthy subject, measured using compression sonography.
Anwander H, Büchel L, Krause F, Siebenrock K, Schmid T
Injury 2022 Feb;53(2):719-723. Epub 2021 Dec 17 doi: 10.1016/j.injury.2021.12.014. PMID: 34963511
A strategy to prevent complications of hyperextension type tibial plateau fracture.
Lin KC, Tarng YW
Eur J Orthop Surg Traumatol 2021 Jan;31(1):71-78. Epub 2020 Jul 26 doi: 10.1007/s00590-020-02739-7. PMID: 32715326
Anterior opening wedge osteotomy of the proximal tibia for anterior knee pain in idiopathic hyperextension knees.
van Raaij TM, de Waal Malefijt J
Int Orthop 2006 Aug;30(4):248-52. Epub 2006 Mar 7 doi: 10.1007/s00264-005-0063-x. PMID: 16521014Free PMC Article

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