U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Conjunctival cicatrization

MedGen UID:
1632169
•Concept ID:
C4703690
•
Finding
Synonyms: Cicatricial conjunctivitis; Cicatrizating conjunctivitis; Conjunctival cicatricial conjunctivitis
 
HPO: HP:0500039

Definition

An abnormality of the conjuctiva and ocular surface caused by conjunctival inflammation and associated with scarring. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVConjunctival cicatrization

Professional guidelines

PubMed

Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management.
Singh S, Donthineni PR, Shanbhag SS, Senthil S, Ong HS, Dart JK, Basu S
Ocul Surf 2022 Apr;24:83-92. Epub 2022 Mar 2 doi: 10.1016/j.jtos.2022.02.004. PMID: 35247582

Recent clinical studies

Etiology

Age-Related Differences in the Clinical Patterns of Ocular Graft-Versus-Host Disease.
Altan-Yaycıoğlu R, Aydın Akova Y, Dönmez O
Turk J Ophthalmol 2022 Dec 28;52(6):366-373. doi: 10.4274/tjo.galenos.2022.50945. PMID: 36578178Free PMC Article
Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management.
Singh S, Donthineni PR, Shanbhag SS, Senthil S, Ong HS, Dart JK, Basu S
Ocul Surf 2022 Apr;24:83-92. Epub 2022 Mar 2 doi: 10.1016/j.jtos.2022.02.004. PMID: 35247582
Dupilumab-Associated Conjunctivitis in Patients With Atopic Dermatitis.
Liberman P, Shifera AS, Berkenstock M
Cornea 2020 Jun;39(6):784-786. doi: 10.1097/ICO.0000000000002262. PMID: 31985517
Paraneoplastic conjunctival cicatrization: two different pathogenic types.
Ahuero AE, Jakobiec FA, Bhat P, Ciralsky JB, Papaliodis GN
Ophthalmology 2010 Apr;117(4):659-64. Epub 2010 Jan 4 doi: 10.1016/j.ophtha.2009.09.006. PMID: 20045572
Cataract surgery in ocular cicatricial pemphigoid.
Sainz de la Maza M, Tauber J, Foster CS
Ophthalmology 1988 Apr;95(4):481-6. doi: 10.1016/s0161-6420(88)33162-3. PMID: 3050692

Diagnosis

Age-Related Differences in the Clinical Patterns of Ocular Graft-Versus-Host Disease.
Altan-Yaycıoğlu R, Aydın Akova Y, Dönmez O
Turk J Ophthalmol 2022 Dec 28;52(6):366-373. doi: 10.4274/tjo.galenos.2022.50945. PMID: 36578178Free PMC Article
Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management.
Singh S, Donthineni PR, Shanbhag SS, Senthil S, Ong HS, Dart JK, Basu S
Ocul Surf 2022 Apr;24:83-92. Epub 2022 Mar 2 doi: 10.1016/j.jtos.2022.02.004. PMID: 35247582
Conjunctival cicatrizing disease presenting with lacrimal obstruction.
Satchi K, McNab AA
Orbit 2016 Dec;35(6):321-323. Epub 2016 Aug 25 doi: 10.1080/01676830.2016.1193539. PMID: 27559621
Cicatricial pemphigoid and dry eye.
Dart J
Semin Ophthalmol 2005 Apr-Jun;20(2):95-100. doi: 10.1080/08820530590931368. PMID: 16020349
Chronic cicatrizing conjunctivitis.
Faraj HG, Hoang-Xuan T
Curr Opin Ophthalmol 2001 Aug;12(4):250-7. doi: 10.1097/00055735-200108000-00003. PMID: 11507337

Therapy

Age-Related Differences in the Clinical Patterns of Ocular Graft-Versus-Host Disease.
Altan-Yaycıoğlu R, Aydın Akova Y, Dönmez O
Turk J Ophthalmol 2022 Dec 28;52(6):366-373. doi: 10.4274/tjo.galenos.2022.50945. PMID: 36578178Free PMC Article
Dupilumab-Associated Conjunctivitis in Patients With Atopic Dermatitis.
Liberman P, Shifera AS, Berkenstock M
Cornea 2020 Jun;39(6):784-786. doi: 10.1097/ICO.0000000000002262. PMID: 31985517
Long-term results of therapy with mycophenolate mofetil in ocular mucous membrane pemphigoid.
Doycheva D, Deuter C, Blumenstock G, Stuebiger N, Zierhut M
Ocul Immunol Inflamm 2011 Dec;19(6):431-8. doi: 10.3109/09273948.2011.624288. PMID: 22106912
Methotrexate therapy for ocular cicatricial pemphigoid.
McCluskey P, Chang JH, Singh R, Wakefield D
Ophthalmology 2004 Apr;111(4):796-801. doi: 10.1016/j.ophtha.2003.07.010. PMID: 15051215
Cataract surgery in ocular cicatricial pemphigoid.
Sainz de la Maza M, Tauber J, Foster CS
Ophthalmology 1988 Apr;95(4):481-6. doi: 10.1016/s0161-6420(88)33162-3. PMID: 3050692

Prognosis

Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management.
Singh S, Donthineni PR, Shanbhag SS, Senthil S, Ong HS, Dart JK, Basu S
Ocul Surf 2022 Apr;24:83-92. Epub 2022 Mar 2 doi: 10.1016/j.jtos.2022.02.004. PMID: 35247582
Evaluation of mucous membrane pemphigoid with ocular involvement in young patients.
Rauz S, Maddison PG, Dart JK
Ophthalmology 2005 Jul;112(7):1268-74. doi: 10.1016/j.ophtha.2005.01.039. PMID: 15921743
Chronic cicatrizing conjunctivitis.
Faraj HG, Hoang-Xuan T
Curr Opin Ophthalmol 2001 Aug;12(4):250-7. doi: 10.1097/00055735-200108000-00003. PMID: 11507337
Subconjunctival mitomycin C for the treatment of ocular cicatricial pemphigoid.
Donnenfeld ED, Perry HD, Wallerstein A, Caronia RM, Kanellopoulos AJ, Sforza PD, D'Aversa G
Ophthalmology 1999 Jan;106(1):72-8; discussion 79. doi: 10.1016/S0161-6420(99)90022-2. PMID: 9917784
Penetrating keratoplasty in cicatrizing conjunctival diseases.
Tugal-Tutkun I, Akova YA, Foster CS
Ophthalmology 1995 Apr;102(4):576-85. doi: 10.1016/s0161-6420(95)30980-3. PMID: 7724175

Clinical prediction guides

Age-Related Differences in the Clinical Patterns of Ocular Graft-Versus-Host Disease.
Altan-Yaycıoğlu R, Aydın Akova Y, Dönmez O
Turk J Ophthalmol 2022 Dec 28;52(6):366-373. doi: 10.4274/tjo.galenos.2022.50945. PMID: 36578178Free PMC Article
Long-term results of therapy with mycophenolate mofetil in ocular mucous membrane pemphigoid.
Doycheva D, Deuter C, Blumenstock G, Stuebiger N, Zierhut M
Ocul Immunol Inflamm 2011 Dec;19(6):431-8. doi: 10.3109/09273948.2011.624288. PMID: 22106912
In vivo confocal microscopy of normal conjunctiva and conjunctivitis.
Messmer EM, Mackert MJ, Zapp DM, Kampik A
Cornea 2006 Aug;25(7):781-8. doi: 10.1097/01.ico.0000224648.74095.90. PMID: 17068454
Evaluation of mucous membrane pemphigoid with ocular involvement in young patients.
Rauz S, Maddison PG, Dart JK
Ophthalmology 2005 Jul;112(7):1268-74. doi: 10.1016/j.ophtha.2005.01.039. PMID: 15921743
The conjunctiva in acute and chronic mucous membrane pemphigoid. An immunohistochemical analysis.
Bernauer W, Wright P, Dart JK, Leonard JN, Lightman S
Ophthalmology 1993 Mar;100(3):339-46. doi: 10.1016/s0161-6420(93)31644-1. PMID: 8460003

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...