U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Conjunctival follicles

MedGen UID:
678585
Concept ID:
C0860499
Finding
Synonym: Conjunctival follicle
SNOMED CT: Conjunctival follicle (421242005)
 
HPO: HP:0030947

Definition

Small, dome-shaped nodules without a prominent central vessel located on the conjunctiva. The lymphoid follicles are located in the subendothelial region of the conjunctiva. They consist of a germinal center that contains immature, proliferating lymphocytes, as well as a corona that contains mature lymphocytes and plasma cells. [from HPO]

Professional guidelines

PubMed

Kim SY, Chung YK, Lee YC, Kim SY
Cornea 2015 Feb;34(2):182-7. doi: 10.1097/ICO.0000000000000332. PMID: 25522221
Meyer-Blazejewska EA, Call MK, Yamanaka O, Liu H, Schlötzer-Schrehardt U, Kruse FE, Kao WW
Stem Cells 2011 Jan;29(1):57-66. doi: 10.1002/stem.550. PMID: 20957740Free PMC Article
Gao YY, Di Pascuale MA, Elizondo A, Tseng SC
Cornea 2007 Feb;26(2):136-43. doi: 10.1097/01.ico.0000244870.62384.79. PMID: 17251800

Recent clinical studies

Etiology

Zhao Y, Chen S, Wang S, Chen Y, Li J, Fu Y, Dai Q, Lin X, Wu Y, Zhao Y
Ocul Surf 2018 Jul;16(3):301-305. Epub 2018 Mar 21 doi: 10.1016/j.jtos.2018.03.006. PMID: 29574281
Aihara M, Adachi M, Hamada N, Honda N, Koseki N, Matsuo H, Miyata K, Otani S, Unoki K
J Ocul Pharmacol Ther 2015 Oct;31(8):482-6. Epub 2015 Jun 26 doi: 10.1089/jop.2014.0174. PMID: 26114331
Goldschmidt P, Vanzzini Zago V, Diaz Vargas L, Espinoza Garcia L, Morales Montoya C, Peralta B, Mercado M
Rev Panam Salud Publica 2007 Jul;22(1):29-34. doi: 10.1590/s1020-49892007000600004. PMID: 17931485
Spaide RF, Ward DL
Br J Ophthalmol 1990 Aug;74(8):469-71. doi: 10.1136/bjo.74.8.469. PMID: 2390521Free PMC Article
Collier LH, Sowa J, Sowa S
J Hyg (Lond) 1972 Dec;70(4):727-40. doi: 10.1017/s0022172400022579. PMID: 4567314Free PMC Article

Diagnosis

Jinagal J, Agarwal A, Negi A, Gupta G, Sharma V, Gupta PC, Ram J
Eur J Ophthalmol 2019 Jul;29(4):NP5-NP8. Epub 2018 Oct 7 doi: 10.1177/1120672118803534. PMID: 30295071
Duncan J, Chen Y, Fuchs D, Cantu C, Wang M
Cornea 2016 Mar;35(3):395-8. doi: 10.1097/ICO.0000000000000696. PMID: 26606298
Goldschmidt P, Vanzzini Zago V, Diaz Vargas L, Espinoza Garcia L, Morales Montoya C, Peralta B, Mercado M
Rev Panam Salud Publica 2007 Jul;22(1):29-34. doi: 10.1590/s1020-49892007000600004. PMID: 17931485
Rao SK, Madhavan HN, Padmanabhan P, Lakshmi GS, Natarajan K, Garg D
Cornea 1996 Jan;15(1):62-5. PMID: 8907382
Spaide RF, Ward DL
Br J Ophthalmol 1990 Aug;74(8):469-71. doi: 10.1136/bjo.74.8.469. PMID: 2390521Free PMC Article

Therapy

Li D, Lu J, Hu Z, Liang J, Lin S
Photobiomodul Photomed Laser Surg 2023 Jan;41(1):17-25. doi: 10.1089/photob.2022.0063. PMID: 36629903
Abikoye TM
Pan Afr Med J 2021;38:166. Epub 2021 Feb 12 doi: 10.11604/pamj.2021.38.166.27121. PMID: 33995773Free PMC Article
Jinagal J, Agarwal A, Negi A, Gupta G, Sharma V, Gupta PC, Ram J
Eur J Ophthalmol 2019 Jul;29(4):NP5-NP8. Epub 2018 Oct 7 doi: 10.1177/1120672118803534. PMID: 30295071
Aihara M, Adachi M, Hamada N, Honda N, Koseki N, Matsuo H, Miyata K, Otani S, Unoki K
J Ocul Pharmacol Ther 2015 Oct;31(8):482-6. Epub 2015 Jun 26 doi: 10.1089/jop.2014.0174. PMID: 26114331
Liesegang TJ
Ophthalmology 1985 Feb;92(2):228-33. doi: 10.1016/s0161-6420(85)34048-4. PMID: 3982802

Prognosis

Abikoye TM
Pan Afr Med J 2021;38:166. Epub 2021 Feb 12 doi: 10.11604/pamj.2021.38.166.27121. PMID: 33995773Free PMC Article
Aihara M, Adachi M, Hamada N, Honda N, Koseki N, Matsuo H, Miyata K, Otani S, Unoki K
J Ocul Pharmacol Ther 2015 Oct;31(8):482-6. Epub 2015 Jun 26 doi: 10.1089/jop.2014.0174. PMID: 26114331
LeBlanc RP
Ophthalmology 1998 Oct;105(10):1960-7. doi: 10.1016/s0161-6420(98)91048-x. PMID: 9787370
Liesegang TJ
Ophthalmology 1985 Feb;92(2):228-33. doi: 10.1016/s0161-6420(85)34048-4. PMID: 3982802
Niitu Y, Horikawa M, Suetake T, Hasegawa S, Komatsu S
Ann N Y Acad Sci 1976;278:532-8. doi: 10.1111/j.1749-6632.1976.tb47067.x. PMID: 1067038

Clinical prediction guides

Li D, Lu J, Hu Z, Liang J, Lin S
Photobiomodul Photomed Laser Surg 2023 Jan;41(1):17-25. doi: 10.1089/photob.2022.0063. PMID: 36629903
Zhao Y, Chen S, Wang S, Chen Y, Li J, Fu Y, Dai Q, Lin X, Wu Y, Zhao Y
Ocul Surf 2018 Jul;16(3):301-305. Epub 2018 Mar 21 doi: 10.1016/j.jtos.2018.03.006. PMID: 29574281
Aihara M, Adachi M, Hamada N, Honda N, Koseki N, Matsuo H, Miyata K, Otani S, Unoki K
J Ocul Pharmacol Ther 2015 Oct;31(8):482-6. Epub 2015 Jun 26 doi: 10.1089/jop.2014.0174. PMID: 26114331
Burton MJ, Hu VH, Massae P, Burr SE, Chevallier C, Afwamba IA, Courtright P, Weiss HA, Mabey DC, Bailey RL
Invest Ophthalmol Vis Sci 2011 Jul 29;52(8):6012-7. doi: 10.1167/iovs.11-7326. PMID: 21693601Free PMC Article
Collier LH, Sowa J, Sowa S
J Hyg (Lond) 1972 Dec;70(4):727-40. doi: 10.1017/s0022172400022579. PMID: 4567314Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...