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Malignant Pericardial Germ Cell Tumor

MedGen UID:
1642847
•Concept ID:
C4687704
•
Neoplastic Process

Definition

A malignant germ cell tumor that arises within the pericardium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Pericardial Germ Cell Tumor

Professional guidelines

PubMed

Prenatal Diagnosis and Outcome of Intrapericardial Teratoma: Report of Two Clinical Scenarios.
Martínez-García A, Cervantes-Salazar J, Copado-Mendoza DY, Aranda-Fraustro A, Barrera-Valdivieso MA, Pereira-López GI, Calderón-Colmenero J
World J Pediatr Congenit Heart Surg 2023 Jan;14(1):88-90. Epub 2022 Oct 16 doi: 10.1177/21501351221129189. PMID: 36250319
Prenatal management of fetal intrapericardial teratoma: a systematic review.
Nassr AA, Shazly SA, Morris SA, Ayres N, Espinoza J, Erfani H, Olutoye OA, Sexson SK, Olutoye OO, Fraser CD Jr, Belfort MA, Shamshirsaz AA
Prenat Diagn 2017 Sep;37(9):849-863. Epub 2017 Aug 7 doi: 10.1002/pd.5113. PMID: 28695637
Treatment strategies for pediatric patients with primary cardiac and pericardial tumors: a 30-year review.
Günther T, Schreiber C, Noebauer C, Eicken A, Lange R
Pediatr Cardiol 2008 Nov;29(6):1071-6. Epub 2008 Jul 4 doi: 10.1007/s00246-008-9256-6. PMID: 18600370

Recent clinical studies

Etiology

Resection of Intrathoracic Paraganglioma With and Without Cardiopulmonary Bypass.
Gurrieri C, Butz JJ, Weingarten TN, Bancos I, Young WF Jr, Cassivi SD, Said SM, McKenzie TJ, Barbara DW, Sprung J
Ann Thorac Surg 2018 Apr;105(4):1160-1167. Epub 2018 Feb 14 doi: 10.1016/j.athoracsur.2017.11.022. PMID: 29452998
Prenatal management of fetal intrapericardial teratoma: a systematic review.
Nassr AA, Shazly SA, Morris SA, Ayres N, Espinoza J, Erfani H, Olutoye OA, Sexson SK, Olutoye OO, Fraser CD Jr, Belfort MA, Shamshirsaz AA
Prenat Diagn 2017 Sep;37(9):849-863. Epub 2017 Aug 7 doi: 10.1002/pd.5113. PMID: 28695637
Cardiac tumors.
Petris AO, Alexandrescu DM, Costache II
Rev Med Chir Soc Med Nat Iasi 2014 Apr-Jun;118(2):289-92. PMID: 25076689
Cytology of pleural, peritoneal and pericardial fluids in children. A 40-year summary.
Wong JW, Pitlik D, Abdul-Karim FW
Acta Cytol 1997 Mar-Apr;41(2):467-73. doi: 10.1159/000332540. PMID: 9100782
Teratomas in childhood.
Bale PM, Painter DM, Cohen D
Pathology 1975 Jul;7(3):209-18. doi: 10.3109/00313027509094411. PMID: 1196679

Diagnosis

Rare mediastinal masses - imaging review.
Patnaik S, Malempati AR, Uppin M, Susarla R
J Cancer Res Ther 2021 Jan-Mar;17(1):13-21. doi: 10.4103/jcrt.JCRT_587_19. PMID: 33723126
Fetal intrapericardial teratomas.
Yuan SM, Lin H
Turk J Pediatr 2019;61(2):153-158. doi: 10.24953/turkjped.2019.02.001. PMID: 31951327
Neoplastic Pericardial Disease.
Maleszewski JJ, Anavekar NS
Cardiol Clin 2017 Nov;35(4):589-600. Epub 2017 Sep 6 doi: 10.1016/j.ccl.2017.07.011. PMID: 29025549
Cardiac tumors.
Petris AO, Alexandrescu DM, Costache II
Rev Med Chir Soc Med Nat Iasi 2014 Apr-Jun;118(2):289-92. PMID: 25076689
Tumors of the mediastinum.
Duwe BV, Sterman DH, Musani AI
Chest 2005 Oct;128(4):2893-909. doi: 10.1378/chest.128.4.2893. PMID: 16236967

Therapy

Chylous effusions in advanced medullary thyroid cancer patients treated with selpercatinib.
Prete A, Gambale C, Cappagli V, Bottici V, Rossi P, Caciagli M, Papini P, Taddei D, Ortori S, Gabbrielli L, Celi A, Materazzi G, Elisei R, Matrone A
Eur J Endocrinol 2022 Dec 1;187(6):905-915. Epub 2022 Nov 29 doi: 10.1530/EJE-22-0643. PMID: 36314655
Successful treatment of radiotherapy and apatinib in patient with mediastinal mixed non-seminomatous germ cell tumor: A case report.
Ren C, Zhao J, Kang L, Di Y, Qiu G, Wang Q
Medicine (Baltimore) 2021 Oct 29;100(43):e27617. doi: 10.1097/MD.0000000000027617. PMID: 34713845Free PMC Article
Thoracic tumor resection combined with SVC replacement using autologous pericardium.
Jiang S, Hu H, Guo C, Jiang F, Liu X, Tang L, Tang J, Cheng X
World J Surg Oncol 2019 Dec 21;17(1):227. doi: 10.1186/s12957-019-1769-3. PMID: 31864362Free PMC Article
Prenatal management of fetal intrapericardial teratoma: a systematic review.
Nassr AA, Shazly SA, Morris SA, Ayres N, Espinoza J, Erfani H, Olutoye OA, Sexson SK, Olutoye OO, Fraser CD Jr, Belfort MA, Shamshirsaz AA
Prenat Diagn 2017 Sep;37(9):849-863. Epub 2017 Aug 7 doi: 10.1002/pd.5113. PMID: 28695637
Cardiac effects of noncardiac neoplasms.
Schoen FJ, Berger BM, Guerina NG
Cardiol Clin 1984 Nov;2(4):657-70. PMID: 6400009

Prognosis

Fetal intrapericardial teratomas.
Yuan SM, Lin H
Turk J Pediatr 2019;61(2):153-158. doi: 10.24953/turkjped.2019.02.001. PMID: 31951327
Cardiac tumors.
Petris AO, Alexandrescu DM, Costache II
Rev Med Chir Soc Med Nat Iasi 2014 Apr-Jun;118(2):289-92. PMID: 25076689
Cardiac tumours in children.
Uzun O, Wilson DG, Vujanic GM, Parsons JM, De Giovanni JV
Orphanet J Rare Dis 2007 Mar 1;2:11. doi: 10.1186/1750-1172-2-11. PMID: 17331235Free PMC Article
Tumors of the mediastinum.
Duwe BV, Sterman DH, Musani AI
Chest 2005 Oct;128(4):2893-909. doi: 10.1378/chest.128.4.2893. PMID: 16236967
Teratomas in childhood.
Bale PM, Painter DM, Cohen D
Pathology 1975 Jul;7(3):209-18. doi: 10.3109/00313027509094411. PMID: 1196679

Clinical prediction guides

A single-center experience of magnetic resonance imaging findings of fetal sacrococcygeal teratomas.
Tosun M, Çam İ, Uslu H, Doğan Y, Anık Y
Turk J Med Sci 2022 Aug;52(4):1190-1196. Epub 2022 Aug 10 doi: 10.55730/1300-0144.5423. PMID: 36326365Free PMC Article
Chylous effusions in advanced medullary thyroid cancer patients treated with selpercatinib.
Prete A, Gambale C, Cappagli V, Bottici V, Rossi P, Caciagli M, Papini P, Taddei D, Ortori S, Gabbrielli L, Celi A, Materazzi G, Elisei R, Matrone A
Eur J Endocrinol 2022 Dec 1;187(6):905-915. Epub 2022 Nov 29 doi: 10.1530/EJE-22-0643. PMID: 36314655
Fetal thoracic teratomas: mediastinal or pericardial?
Oliver ER, Didier RA, Horii SC, Hedrick HL, Khalek N, DeBari SE, Adzick NS, Coleman BG
Pediatr Radiol 2022 Nov;52(12):2319-2328. Epub 2022 Apr 26 doi: 10.1007/s00247-022-05367-x. PMID: 35471666
Fetal intrapericardial teratomas.
Yuan SM, Lin H
Turk J Pediatr 2019;61(2):153-158. doi: 10.24953/turkjped.2019.02.001. PMID: 31951327
Unusual primary tumors of the heart.
Vander Salm TJ
Semin Thorac Cardiovasc Surg 2000 Apr;12(2):89-100. doi: 10.1053/ct.2000.5080. PMID: 10807431

Recent systematic reviews

A Systematic Review and Meta-Analysis of Prevalence and Outcomes of Cardiac Metastasis of Neuroendocrine Malignancies.
Hamza M, Manasrah N, Patel NN, Sattar Y, Patel B
Am J Cardiol 2023 May 1;194:86-92. Epub 2023 Mar 29 doi: 10.1016/j.amjcard.2023.02.011. PMID: 36996525
Metastatic melanoma of the heart: Retrospective cohort study and systematic review of prevalence, clinical characteristics, and outcomes.
Balinski AM, Vasbinder AL, Kerndt CC, Catalan TC, Parry NP, Rehman RA, Blakely P, Yeow RY, Leja MJ, Lao CD, Fecher LA, Hayek SS
Cancer Med 2023 Feb;12(3):2356-2367. Epub 2022 Jul 27 doi: 10.1002/cam4.5058. PMID: 35894689Free PMC Article
Primary and metastatic primitive neuroectodermal tumor of the heart: A systematic review.
Hajsadeghi S, Iranpour A, Amouei E, Tehrani NH, Ghavidel A, Ziaie H, Asadi O, Moradians V, Tayebi A, Mestres CA, Manqoutaei SA
Asian Cardiovasc Thorac Ann 2022 Sep;30(7):761-771. Epub 2022 Mar 21 doi: 10.1177/02184923221083434. PMID: 35306869
Early treatment of intrapericardial teratoma: a case presentation and systematic literature review.
Cavalcante CTMB, Pinto Júnior VC, Pompeu RG, Férrer JVCC, Cavalcante MB, Araujo Júnior E, Peixoto AB, Castello Branco KM
J Matern Fetal Neonatal Med 2019 Jul;32(13):2262-2268. Epub 2018 Jan 22 doi: 10.1080/14767058.2018.1427059. PMID: 29320914
Prenatal management of fetal intrapericardial teratoma: a systematic review.
Nassr AA, Shazly SA, Morris SA, Ayres N, Espinoza J, Erfani H, Olutoye OA, Sexson SK, Olutoye OO, Fraser CD Jr, Belfort MA, Shamshirsaz AA
Prenat Diagn 2017 Sep;37(9):849-863. Epub 2017 Aug 7 doi: 10.1002/pd.5113. PMID: 28695637

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