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Refractory Urothelial Carcinoma

MedGen UID:
1659806
Concept ID:
C4725681
Neoplastic Process

Definition

Urothelial carcinoma that does not respond to treatment. [from NCI]

Professional guidelines

PubMed

Powles T, Necchi A, Rosen G, Hariharan S, Apolo AB
Clin Genitourin Cancer 2018 Apr;16(2):117-129. Epub 2017 Dec 6 doi: 10.1016/j.clgc.2017.11.002. PMID: 29325739Free PMC Article
Tu SM, Millikan RE, Pagliaro LC, Daliani D, Papandreou CN, Kim J, Chen DT, Williams DL, Logothetis CJ
Urol Oncol 2003 Sep-Oct;21(5):342-8. doi: 10.1016/s1078-1439(02)00300-9. PMID: 14670540

Recent clinical studies

Etiology

Bitting RL, Tooze JA, Goodman M, Vile DC, Brown JM, Thomas CY, Neve M, Kooshki M, Addo S, Triozzi PL, Dubey P
Cancer Res Commun 2024 Feb 26;4(2):530-539. doi: 10.1158/2767-9764.CRC-23-0436. PMID: 38345536Free PMC Article
Ito K, Kita Y, Kobayashi T
Int J Urol 2023 Sep;30(9):696-703. Epub 2022 Dec 9 doi: 10.1111/iju.15101. PMID: 36482843
Uchimoto T, Fukushima T, Komura K, Fukuokaya W, Adachi T, Hashimoto T, Yoshizawa A, Nakamura K, Yano Y, Nishimura K, Nishio K, Nakamori K, Iwatani K, Yamamoto S, Urabe F, Mori K, Yanagisawa T, Tsuduki S, Takahara K, Inamoto T, Miki J, Kimura T, Ohno Y, Shiroki R, Egawa S, Azuma H
BJU Int 2023 Apr;131(4):477-485. Epub 2022 Sep 26 doi: 10.1111/bju.15893. PMID: 36098556
Yumioka T, Honda M, Shimizu R, Teraoka S, Yamaguchi N, Kawamoto B, Iwamoto H, Morizane S, Hikita K, Takenaka A
Anticancer Res 2021 Nov;41(11):5767-5773. doi: 10.21873/anticanres.15393. PMID: 34732450
Tafuri A, Smith DD, Cacciamani GE, Cole S, Shakir A, Sadeghi S, Vogelzang NJ, Quinn D, Gill PS, Gill IS
Clin Genitourin Cancer 2020 Oct;18(5):351-360.e3. Epub 2020 Jan 31 doi: 10.1016/j.clgc.2020.01.004. PMID: 32146152Free PMC Article

Diagnosis

Uchimoto T, Fukushima T, Komura K, Fukuokaya W, Adachi T, Hashimoto T, Yoshizawa A, Nakamura K, Yano Y, Nishimura K, Nishio K, Nakamori K, Iwatani K, Yamamoto S, Urabe F, Mori K, Yanagisawa T, Tsuduki S, Takahara K, Inamoto T, Miki J, Kimura T, Ohno Y, Shiroki R, Egawa S, Azuma H
BJU Int 2023 Apr;131(4):477-485. Epub 2022 Sep 26 doi: 10.1111/bju.15893. PMID: 36098556

Therapy

Matsubara N, de Wit R, Balar AV, Siefker-Radtke AO, Zolnierek J, Csoszi T, Shin SJ, Park SH, Atduev V, Gumus M, Su YL, Karaca SB, Cutuli HJ, Sendur MAN, Shen L, O'Hara K, Okpara CE, Franco S, Moreno BH, Grivas P, Loriot Y
Eur Urol 2024 Mar;85(3):229-238. Epub 2023 Sep 29 doi: 10.1016/j.eururo.2023.08.012. PMID: 37778952
Ito K, Kita Y, Kobayashi T
Int J Urol 2023 Sep;30(9):696-703. Epub 2022 Dec 9 doi: 10.1111/iju.15101. PMID: 36482843
Uchimoto T, Fukushima T, Komura K, Fukuokaya W, Adachi T, Hashimoto T, Yoshizawa A, Nakamura K, Yano Y, Nishimura K, Nishio K, Nakamori K, Iwatani K, Yamamoto S, Urabe F, Mori K, Yanagisawa T, Tsuduki S, Takahara K, Inamoto T, Miki J, Kimura T, Ohno Y, Shiroki R, Egawa S, Azuma H
BJU Int 2023 Apr;131(4):477-485. Epub 2022 Sep 26 doi: 10.1111/bju.15893. PMID: 36098556
Apolo AB, Nadal R, Tomita Y, Davarpanah NN, Cordes LM, Steinberg SM, Cao L, Parnes HL, Costello R, Merino MJ, Folio LR, Lindenberg L, Raffeld M, Lin J, Lee MJ, Lee S, Alarcon SV, Yuno A, Dawson NA, Allette K, Roy A, De Silva D, Lee MM, Sissung TM, Figg WD, Agarwal PK, Wright JJ, Ning YM, Gulley JL, Dahut WL, Bottaro DP, Trepel JB
Lancet Oncol 2020 Aug;21(8):1099-1109. Epub 2020 Jul 6 doi: 10.1016/S1470-2045(20)30202-3. PMID: 32645282Free PMC Article
Iyer G, Milowsky MI, Bajorin DF
Expert Rev Anticancer Ther 2010 Dec;10(12):1917-32. doi: 10.1586/era.10.182. PMID: 21110758Free PMC Article

Prognosis

Nishio K, Higashio T, Komura K, Fukuokaya W, Adachi T, Hirasawa Y, Hashimoto T, Yoshizawa A, Tsuchida S, Matsuda T, Tsujino T, Nishimura K, Tokushige S, Nakamori K, Uchimoto T, Yamamoto S, Iwatani K, Urabe F, Mori K, Yanagisawa T, Tsuduki S, Takahara K, Inamoto T, Miki J, Kimura T, Ohno Y, Shiroki R, Azuma H
Oncology 2024;102(6):457-464. Epub 2023 Oct 13 doi: 10.1159/000534554. PMID: 37839399
Gómez de Liaño Lista A, van Dijk N, de Velasco Oria de Rueda G, Necchi A, Lavaud P, Morales-Barrera R, Alonso Gordoa T, Maroto P, Ravaud A, Durán I, Szabados B, Castellano D, Giannatempo P, Loriot Y, Carles J, Anguera Palacios G, Lefort F, Raggi D, Gross Goupil M, Powles T, Van der Heijden MS
Eur Urol 2020 Feb;77(2):269-276. Epub 2019 Nov 5 doi: 10.1016/j.eururo.2019.10.004. PMID: 31699525
Iyer G, Milowsky MI, Bajorin DF
Expert Rev Anticancer Ther 2010 Dec;10(12):1917-32. doi: 10.1586/era.10.182. PMID: 21110758Free PMC Article
Tu SM, Millikan RE, Pagliaro LC, Daliani D, Papandreou CN, Kim J, Chen DT, Williams DL, Logothetis CJ
Urol Oncol 2003 Sep-Oct;21(5):342-8. doi: 10.1016/s1078-1439(02)00300-9. PMID: 14670540
Nishimura M, Nasu K, Ohta H, Shintaku M, Takahashi Y
Cancer 1999 Nov 1;86(9):1827-31. doi: 10.1002/(sici)1097-0142(19991101)86:9<1827::aid-cncr26>3.0.co;2-#. PMID: 10547557

Clinical prediction guides

Nishio K, Higashio T, Komura K, Fukuokaya W, Adachi T, Hirasawa Y, Hashimoto T, Yoshizawa A, Tsuchida S, Matsuda T, Tsujino T, Nishimura K, Tokushige S, Nakamori K, Uchimoto T, Yamamoto S, Iwatani K, Urabe F, Mori K, Yanagisawa T, Tsuduki S, Takahara K, Inamoto T, Miki J, Kimura T, Ohno Y, Shiroki R, Azuma H
Oncology 2024;102(6):457-464. Epub 2023 Oct 13 doi: 10.1159/000534554. PMID: 37839399
Uchimoto T, Fukushima T, Komura K, Fukuokaya W, Adachi T, Hashimoto T, Yoshizawa A, Nakamura K, Yano Y, Nishimura K, Nishio K, Nakamori K, Iwatani K, Yamamoto S, Urabe F, Mori K, Yanagisawa T, Tsuduki S, Takahara K, Inamoto T, Miki J, Kimura T, Ohno Y, Shiroki R, Egawa S, Azuma H
BJU Int 2023 Apr;131(4):477-485. Epub 2022 Sep 26 doi: 10.1111/bju.15893. PMID: 36098556
Yumioka T, Honda M, Shimizu R, Teraoka S, Yamaguchi N, Kawamoto B, Iwamoto H, Morizane S, Hikita K, Takenaka A
Anticancer Res 2021 Nov;41(11):5767-5773. doi: 10.21873/anticanres.15393. PMID: 34732450
Gómez de Liaño Lista A, van Dijk N, de Velasco Oria de Rueda G, Necchi A, Lavaud P, Morales-Barrera R, Alonso Gordoa T, Maroto P, Ravaud A, Durán I, Szabados B, Castellano D, Giannatempo P, Loriot Y, Carles J, Anguera Palacios G, Lefort F, Raggi D, Gross Goupil M, Powles T, Van der Heijden MS
Eur Urol 2020 Feb;77(2):269-276. Epub 2019 Nov 5 doi: 10.1016/j.eururo.2019.10.004. PMID: 31699525
Narayanan S, Lam A, Vaishampayan U, Harshman L, Fan A, Pachynski R, Poushnejad S, Haas D, Li S, Srinivas S
Clin Genitourin Cancer 2016 Oct;14(5):432-437. Epub 2016 Mar 12 doi: 10.1016/j.clgc.2016.03.011. PMID: 27068017Free PMC Article

Recent systematic reviews

Tafuri A, Smith DD, Cacciamani GE, Cole S, Shakir A, Sadeghi S, Vogelzang NJ, Quinn D, Gill PS, Gill IS
Clin Genitourin Cancer 2020 Oct;18(5):351-360.e3. Epub 2020 Jan 31 doi: 10.1016/j.clgc.2020.01.004. PMID: 32146152Free PMC Article

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