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Refractory Synovial Sarcoma

MedGen UID:
1664380
•Concept ID:
C4724967
•
Neoplastic Process

Definition

Synovial sarcoma that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Synovial Sarcoma

Professional guidelines

PubMed

Advances in the Management of Pediatric Sarcomas.
Hernandez Tejada FN, Zamudio A, Marques-Piubelli ML, Cuglievan B, Harrison D
Curr Oncol Rep 2020 Nov 16;23(1):3. doi: 10.1007/s11912-020-00995-8. PMID: 33196879
Antiangiogenic approaches for the treatment of advanced synovial sarcomas.
Do K, Doroshow JH, Kummar S
Curr Opin Oncol 2012 Jul;24(4):425-30. doi: 10.1097/CCO.0b013e328354c141. PMID: 22572725Free PMC Article
Systemic treatment options for patients with refractory adult-type sarcoma beyond anthracyclines.
Hartmann JT
Anticancer Drugs 2007 Mar;18(3):245-54. doi: 10.1097/CAD.0b013e3280124e41. PMID: 17264755

Recent clinical studies

Therapy

Anlotinib inhibits synovial sarcoma by targeting GINS1: a novel downstream target oncogene in progression of synovial sarcoma.
Tang L, Yu W, Wang Y, Li H, Shen Z
Clin Transl Oncol 2019 Dec;21(12):1624-1633. Epub 2019 Apr 8 doi: 10.1007/s12094-019-02090-2. PMID: 30963468

Prognosis

Anlotinib inhibits synovial sarcoma by targeting GINS1: a novel downstream target oncogene in progression of synovial sarcoma.
Tang L, Yu W, Wang Y, Li H, Shen Z
Clin Transl Oncol 2019 Dec;21(12):1624-1633. Epub 2019 Apr 8 doi: 10.1007/s12094-019-02090-2. PMID: 30963468

Clinical prediction guides

Guillain-Barre syndrome observed with adoptive transfer of lymphocytes genetically engineered with an NY-ESO-1 reactive T-cell receptor.
Joseph J, Nathenson MJ, Trinh VA, Malik K, Nowell E, Carter K, Weathers SP, Demetri GD, Araujo D, Conley AP
J Immunother Cancer 2019 Nov 8;7(1):296. doi: 10.1186/s40425-019-0759-x. PMID: 31703609Free PMC Article

Supplemental Content

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    Practice guidelines

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    • PMC Articles
      Related information in PubMed Central Links
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