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Refractory Malignant Soft Tissue Neoplasm

MedGen UID:
1652605
•Concept ID:
C4725813
•
Neoplastic Process

Definition

Malignant soft tissue neoplasm that is resistant to treatment. [from NCI]

Professional guidelines

PubMed

Rehabilitation Medicine Approaches to Pain Management.
Cheville AL, Smith SR, Basford JR
Hematol Oncol Clin North Am 2018 Jun;32(3):469-482. Epub 2018 Mar 17 doi: 10.1016/j.hoc.2018.02.001. PMID: 29729782
The management of osteoradionecrosis of the jaws--a review.
Rice N, Polyzois I, Ekanayake K, Omer O, Stassen LF
Surgeon 2015 Apr;13(2):101-9. Epub 2014 Jul 30 doi: 10.1016/j.surge.2014.07.003. PMID: 25084627
Endoglin for targeted cancer treatment.
Rosen LS, Gordon MS, Robert F, Matei DE
Curr Oncol Rep 2014 Feb;16(2):365. doi: 10.1007/s11912-013-0365-x. PMID: 24445497

Recent clinical studies

Etiology

Extramedullary disease in multiple myeloma: a systematic literature review.
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
Randomized Phase II Trial of Vincristine-Irinotecan With or Without Temozolomide, in Children and Adults With Relapsed or Refractory Rhabdomyosarcoma: A European Paediatric Soft Tissue Sarcoma Study Group and Innovative Therapies for Children With Cancer Trial.
Defachelles AS, Bogart E, Casanova M, Merks JHM, Bisogno G, Calareso G, Gallego Melcon S, Gatz SA, Le Deley MC, McHugh K, Probst A, Rocourt N, van Rijn RR, Wheatley K, Minard-Colin V, Chisholm JC
J Clin Oncol 2021 Sep 20;39(27):2979-2990. Epub 2021 Aug 3 doi: 10.1200/JCO.21.00124. PMID: 34343032
ICE Regimen for Relapsed/Refractory Bone and Soft Tissue Sarcomas in Children.
Aydin B, Akyuz C, Varan A, Yalcin B, Kurucu N, Kutluk T
Rev Recent Clin Trials 2018;13(2):126-131. doi: 10.2174/1574887113666180124114818. PMID: 29366426
The management of osteoradionecrosis of the jaws--a review.
Rice N, Polyzois I, Ekanayake K, Omer O, Stassen LF
Surgeon 2015 Apr;13(2):101-9. Epub 2014 Jul 30 doi: 10.1016/j.surge.2014.07.003. PMID: 25084627
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group.
Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, Eisenberger MA, Higano C, Bubley GJ, Dreicer R, Petrylak D, Kantoff P, Basch E, Kelly WK, Figg WD, Small EJ, Beer TM, Wilding G, Martin A, Hussain M; Prostate Cancer Clinical Trials Working Group
J Clin Oncol 2008 Mar 1;26(7):1148-59. doi: 10.1200/JCO.2007.12.4487. PMID: 18309951Free PMC Article

Diagnosis

Extramedullary disease in multiple myeloma: a systematic literature review.
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
ICE Regimen for Relapsed/Refractory Bone and Soft Tissue Sarcomas in Children.
Aydin B, Akyuz C, Varan A, Yalcin B, Kurucu N, Kutluk T
Rev Recent Clin Trials 2018;13(2):126-131. doi: 10.2174/1574887113666180124114818. PMID: 29366426
Neuroimaging in the evaluation of epilepsy.
Velez-Ruiz NJ, Klein JP
Semin Neurol 2012 Sep;32(4):361-73. Epub 2013 Jan 29 doi: 10.1055/s-0032-1331809. PMID: 23361482
Snapping scapula syndrome.
Lazar MA, Kwon YW, Rokito AS
J Bone Joint Surg Am 2009 Sep;91(9):2251-62. doi: 10.2106/JBJS.H.01347. PMID: 19724005
Parathyroid storm.
Bayat-Mokhtari F, Palmieri GM, Moinuddin M, Pourmand R
Arch Intern Med 1980 Aug;140(8):1092-5. PMID: 7396615

Therapy

Randomized Phase II Trial of Vincristine-Irinotecan With or Without Temozolomide, in Children and Adults With Relapsed or Refractory Rhabdomyosarcoma: A European Paediatric Soft Tissue Sarcoma Study Group and Innovative Therapies for Children With Cancer Trial.
Defachelles AS, Bogart E, Casanova M, Merks JHM, Bisogno G, Calareso G, Gallego Melcon S, Gatz SA, Le Deley MC, McHugh K, Probst A, Rocourt N, van Rijn RR, Wheatley K, Minard-Colin V, Chisholm JC
J Clin Oncol 2021 Sep 20;39(27):2979-2990. Epub 2021 Aug 3 doi: 10.1200/JCO.21.00124. PMID: 34343032
Apatinib as targeted therapy for advanced bone and soft tissue sarcoma: a dilemma of reversing multidrug resistance while suffering drug resistance itself.
Yang QK, Chen T, Wang SQ, Zhang XJ, Yao ZX
Angiogenesis 2020 Aug;23(3):279-298. Epub 2020 Apr 24 doi: 10.1007/s10456-020-09716-y. PMID: 32333216
The management of osteoradionecrosis of the jaws--a review.
Rice N, Polyzois I, Ekanayake K, Omer O, Stassen LF
Surgeon 2015 Apr;13(2):101-9. Epub 2014 Jul 30 doi: 10.1016/j.surge.2014.07.003. PMID: 25084627
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group.
Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, Eisenberger MA, Higano C, Bubley GJ, Dreicer R, Petrylak D, Kantoff P, Basch E, Kelly WK, Figg WD, Small EJ, Beer TM, Wilding G, Martin A, Hussain M; Prostate Cancer Clinical Trials Working Group
J Clin Oncol 2008 Mar 1;26(7):1148-59. doi: 10.1200/JCO.2007.12.4487. PMID: 18309951Free PMC Article
Docetaxel.
Cortes JE, Pazdur R
J Clin Oncol 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643. PMID: 7595719

Prognosis

Evaluation of isatuximab in patients with soft-tissue plasmacytomas: An analysis from ICARIA-MM and IKEMA.
Beksac M, Spicka I, Hajek R, Bringhen S, Jelínek T, Martin T, Mikala G, Moreau P, Symeonidis A, Rawlings AM, van de Velde H, Richardson PG
Leuk Res 2022 Nov;122:106948. Epub 2022 Sep 6 doi: 10.1016/j.leukres.2022.106948. PMID: 36108425
Extramedullary disease in multiple myeloma: a systematic literature review.
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
ICE Regimen for Relapsed/Refractory Bone and Soft Tissue Sarcomas in Children.
Aydin B, Akyuz C, Varan A, Yalcin B, Kurucu N, Kutluk T
Rev Recent Clin Trials 2018;13(2):126-131. doi: 10.2174/1574887113666180124114818. PMID: 29366426
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group.
Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, Eisenberger MA, Higano C, Bubley GJ, Dreicer R, Petrylak D, Kantoff P, Basch E, Kelly WK, Figg WD, Small EJ, Beer TM, Wilding G, Martin A, Hussain M; Prostate Cancer Clinical Trials Working Group
J Clin Oncol 2008 Mar 1;26(7):1148-59. doi: 10.1200/JCO.2007.12.4487. PMID: 18309951Free PMC Article
Docetaxel.
Cortes JE, Pazdur R
J Clin Oncol 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643. PMID: 7595719

Clinical prediction guides

Alveolar soft part sarcoma: progress toward improvement in survival? A population-based study.
Fujiwara T, Nakata E, Kunisada T, Ozaki T, Kawai A
BMC Cancer 2022 Aug 15;22(1):891. doi: 10.1186/s12885-022-09968-5. PMID: 35971085Free PMC Article
Real-World Evidence of Daratumumab Monotherapy in Relapsed/Refractory Multiple Myeloma Patients and Efficacy on Soft-Tissue Plasmacytomas.
Moreno DF, Clapés V, Soler JA, González-Montes Y, Gironella M, Motlló C, Granell M, Abella E, García-Pintos M, García-Guiñón A, Cabezudo E, Bladé J, Rosiñol L
Clin Lymphoma Myeloma Leuk 2022 Aug;22(8):635-642. Epub 2022 Apr 17 doi: 10.1016/j.clml.2022.04.014. PMID: 35610120
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group.
Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, Eisenberger MA, Higano C, Bubley GJ, Dreicer R, Petrylak D, Kantoff P, Basch E, Kelly WK, Figg WD, Small EJ, Beer TM, Wilding G, Martin A, Hussain M; Prostate Cancer Clinical Trials Working Group
J Clin Oncol 2008 Mar 1;26(7):1148-59. doi: 10.1200/JCO.2007.12.4487. PMID: 18309951Free PMC Article
New therapeutic strategies for soft tissue sarcomas.
von Mehren M
Curr Treat Options Oncol 2003 Dec;4(6):441-51. doi: 10.1007/s11864-003-0045-4. PMID: 14585225
Docetaxel.
Cortes JE, Pazdur R
J Clin Oncol 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643. PMID: 7595719

Recent systematic reviews

Extramedullary disease in multiple myeloma: a systematic literature review.
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article

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