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Thoracic Esophagus Adenocarcinoma

MedGen UID:
1665639
•Concept ID:
C4725594
•
Neoplastic Process

Definition

An adenocarcinoma that arises from the thoracic esophagus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThoracic Esophagus Adenocarcinoma

Professional guidelines

PubMed

Advances in diagnosis and management of cancer of the esophagus.
Deboever N, Jones CM, Yamashita K, Ajani JA, Hofstetter WL
BMJ 2024 Jun 3;385:e074962. doi: 10.1136/bmj-2023-074962. PMID: 38830686
Neoadjuvant Treatment for Stage IIA Esophageal Adenocarcinoma, No Harm No Foul?
Alvarado CE, Worrell SG
Ann Surg Oncol 2024 Feb;31(2):718-719. Epub 2023 Dec 13 doi: 10.1245/s10434-023-14678-8. PMID: 38091147
Surgical management of gastroesophageal junction tumors.
Amenabar A, Hoppo T, Jobe BA
Semin Radiat Oncol 2013 Jan;23(1):16-23. doi: 10.1016/j.semradonc.2012.09.002. PMID: 23207043

Recent clinical studies

Etiology

Surgical approach to advanced Siewert II cancer: beyond the borders? The West Side.
Hölscher AH, Bollschweiler E, Fetzner UK, Babic B
Updates Surg 2023 Feb;75(2):329-333. Epub 2022 Aug 24 doi: 10.1007/s13304-022-01363-w. PMID: 36001282
Esophageal Cancer: Tumor-Node-Metastasis Staging.
Betancourt-Cuellar SL, Benveniste MFK, Palacio DP, Hofstetter WL
Radiol Clin North Am 2021 Mar;59(2):219-229. doi: 10.1016/j.rcl.2020.11.008. PMID: 33551083
Mucosal Ablation Techniques for Barrett's Esophagus and Early Esophageal Cancer.
Rajaram R, Hofstetter WL
Thorac Surg Clin 2018 Nov;28(4):473-480. doi: 10.1016/j.thorsurg.2018.07.004. PMID: 30268293
Management of Gastroesophageal Junction Tumors.
Okereke IC
Surg Clin North Am 2017 Apr;97(2):265-275. Epub 2017 Feb 14 doi: 10.1016/j.suc.2016.11.004. PMID: 28325186
The dilemma of T1 esophageal adenocarcinoma.
Molena D, DeMeester SR
J Thorac Cardiovasc Surg 2017 May;153(5):1206-1207. Epub 2017 Feb 16 doi: 10.1016/j.jtcvs.2016.10.106. PMID: 28314532

Diagnosis

Pulmonary Large Cell Neuroendocrine Carcinoma.
Yang L, Fan Y, Lu H
Pathol Oncol Res 2022;28:1610730. Epub 2022 Oct 11 doi: 10.3389/pore.2022.1610730. PMID: 36304941Free PMC Article
Esophageal adenocarcinoma: A dire need for early detection and treatment.
Joseph A, Raja S, Kamath S, Jang S, Allende D, McNamara M, Videtic G, Murthy S, Bhatt A
Cleve Clin J Med 2022 May 2;89(5):269-279. doi: 10.3949/ccjm.89a.21053. PMID: 35500930
Esophageal Cancer: Tumor-Node-Metastasis Staging.
Betancourt-Cuellar SL, Benveniste MFK, Palacio DP, Hofstetter WL
Radiol Clin North Am 2021 Mar;59(2):219-229. doi: 10.1016/j.rcl.2020.11.008. PMID: 33551083
Management of Gastroesophageal Junction Tumors.
Okereke IC
Surg Clin North Am 2017 Apr;97(2):265-275. Epub 2017 Feb 14 doi: 10.1016/j.suc.2016.11.004. PMID: 28325186
Molecular surgery for cancer.
Roth JA
Arch Surg 1992 Nov;127(11):1298-302. doi: 10.1001/archsurg.1992.01420110040010. PMID: 1444790

Therapy

The dilemma of T1 esophageal adenocarcinoma.
Molena D, DeMeester SR
J Thorac Cardiovasc Surg 2017 May;153(5):1206-1207. Epub 2017 Feb 16 doi: 10.1016/j.jtcvs.2016.10.106. PMID: 28314532
Emerging therapeutic targets in esophageal adenocarcinoma.
Gaur P, Hunt CR, Pandita TK
Oncotarget 2016 Jul 26;7(30):48644-48655. doi: 10.18632/oncotarget.8777. PMID: 27102294Free PMC Article
Surgical Management of Barrett's Esophagus.
Peyre CG, Watson TJ
Gastroenterol Clin North Am 2015 Jun;44(2):459-71. Epub 2015 Mar 24 doi: 10.1016/j.gtc.2015.02.013. PMID: 26021205
Incidence and treatment of brain metastasis in patients with esophageal carcinoma.
Feng W, Zhang P, Zheng X, Chen M, Mao WM
World J Gastroenterol 2015 May 21;21(19):5805-12. doi: 10.3748/wjg.v21.i19.5805. PMID: 26019444Free PMC Article
Treatment of esophageal carcinoma.
Lerut T, Coosemans W, De Leyn P, Van Raemdonck D, Deneffe G, Decker G
Chest 1999 Dec;116(6 Suppl):463S-465S. doi: 10.1378/chest.116.suppl_3.463s. PMID: 10619509

Prognosis

Esophageal adenocarcinoma: A dire need for early detection and treatment.
Joseph A, Raja S, Kamath S, Jang S, Allende D, McNamara M, Videtic G, Murthy S, Bhatt A
Cleve Clin J Med 2022 May 2;89(5):269-279. doi: 10.3949/ccjm.89a.21053. PMID: 35500930
Treatment of Anastomotic Recurrence After Esophagectomy.
Carr RA, Harrington C, Vos E, Bains MS, Bott MJ, Isbell JM, Park BJ, Sihag S, Jones DR, Molena D
Ann Thorac Surg 2022 Aug;114(2):418-425. Epub 2021 Sep 10 doi: 10.1016/j.athoracsur.2021.07.101. PMID: 34509415Free PMC Article
Management of Gastroesophageal Junction Tumors.
Okereke IC
Surg Clin North Am 2017 Apr;97(2):265-275. Epub 2017 Feb 14 doi: 10.1016/j.suc.2016.11.004. PMID: 28325186
Emerging therapeutic targets in esophageal adenocarcinoma.
Gaur P, Hunt CR, Pandita TK
Oncotarget 2016 Jul 26;7(30):48644-48655. doi: 10.18632/oncotarget.8777. PMID: 27102294Free PMC Article
Treatment of esophageal carcinoma.
Lerut T, Coosemans W, De Leyn P, Van Raemdonck D, Deneffe G, Decker G
Chest 1999 Dec;116(6 Suppl):463S-465S. doi: 10.1378/chest.116.suppl_3.463s. PMID: 10619509

Clinical prediction guides

Patient-derived organoids for prediction of treatment response in oesophageal adenocarcinoma.
Bolger JC, Allen J, Radulovich N, Ng C, Derouet M, Shathasivam P, Wilson GW, Tsao MS, Elimova E, Darling GE, Yeung JC
Br J Surg 2024 Jan 3;111(1) doi: 10.1093/bjs/znad408. PMID: 38284787
Low Subcutaneous Adiposity and Mortality in Esophageal Cancer.
Zhou MJ, Tseng L, Guo X, Jin Z, Bentley-Hibbert S, Shen S, Araujo JL, Spinelli CF, Altorki NK, Sonett JR, Neugut AI, Abrams JA
Cancer Epidemiol Biomarkers Prev 2021 Jan;30(1):114-122. Epub 2020 Oct 2 doi: 10.1158/1055-9965.EPI-20-0737. PMID: 33008872
Anti-inflammatory microenvironment of esophageal adenocarcinomas negatively impacts survival.
Karstens KF, Kempski J, Giannou AD, Pelczar P, Steglich B, Steurer S, Freiwald E, Woestemeier A, Konczalla L, Tachezy M, Reeh M, Bockhorn M, Perez D, Mann O, Lohse AW, Roesch T, Izbicki JR, Gagliani N, Huber S
Cancer Immunol Immunother 2020 Jun;69(6):1043-1056. Epub 2020 Feb 25 doi: 10.1007/s00262-020-02517-8. PMID: 32100077Free PMC Article
Is a Novel Nomogram Better Than TNM Staging at Predicting Survival in Siewert Type 2 Adenocarcinoma?
Song KJ, Arndt AT
Ann Surg Oncol 2019 May;26(5):1182-1183. Epub 2019 Feb 15 doi: 10.1245/s10434-019-07242-w. PMID: 30771117
Incidence and treatment of brain metastasis in patients with esophageal carcinoma.
Feng W, Zhang P, Zheng X, Chen M, Mao WM
World J Gastroenterol 2015 May 21;21(19):5805-12. doi: 10.3748/wjg.v21.i19.5805. PMID: 26019444Free PMC Article

Recent systematic reviews

Effect of different surgical approaches on the survival and safety of Siewert type II esophagogastric junction adenocarcinoma: a systematic review and meta-analysis.
Zheng H, Yin X, Pan T, Tao X, Xu X, Li Z
BMC Cancer 2023 Nov 21;23(1):1130. doi: 10.1186/s12885-023-11640-5. PMID: 37990193Free PMC Article
Systematic review and validation of clinical models predicting survival after oesophagectomy for adenocarcinoma.
Boshier PR, Swaray A, Vadhwana B, O'Sullivan A, Low DE, Hanna GB, Peters CJ
Br J Surg 2022 Apr 19;109(5):418-425. doi: 10.1093/bjs/znac044. PMID: 35233634Free PMC Article
Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer.
Vellayappan BA, Soon YY, Ku GY, Leong CN, Lu JJ, Tey JC
Cochrane Database Syst Rev 2017 Aug 22;8(8):CD010511. doi: 10.1002/14651858.CD010511.pub2. PMID: 28829911Free PMC Article
A Systematic Review of Esophageal MicroRNA Markers for Diagnosis and Monitoring of Barrett's Esophagus.
Mallick R, Patnaik SK, Wani S, Bansal A
Dig Dis Sci 2016 Apr;61(4):1039-50. Epub 2015 Nov 14 doi: 10.1007/s10620-015-3959-3. PMID: 26572780
Longitudinal and circumferential resection margin in adenocarcinoma of distal esophagus and cardia.
Migliore M, Rassl D, Criscione A
Future Oncol 2014 Apr;10(5):891-901. doi: 10.2217/fon.13.241. PMID: 24799068

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