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Hormone Receptor-Positive Breast Carcinoma

MedGen UID:
1670518
•Concept ID:
C4745240
•
Neoplastic Process
Synonyms: Hormone Receptor Positive Breast Adenocarcinoma; Hormone Receptor Positive Breast Carcinoma

Definition

Breast adenocarcinoma that is positive for hormone receptors. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHormone Receptor-Positive Breast Carcinoma

Professional guidelines

PubMed

Treatment of Breast Cancer in Young Adults.
Tesch ME, Partridge AH
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-12. doi: 10.1200/EDBK_360970. PMID: 35580291
Breast Cancer Treatment: A Review.
Waks AG, Winer EP
JAMA 2019 Jan 22;321(3):288-300. doi: 10.1001/jama.2018.19323. PMID: 30667505
Treatment of breast cancer.
Maughan KL, Lutterbie MA, Ham PS
Am Fam Physician 2010 Jun 1;81(11):1339-46. PMID: 20521754

Recent clinical studies

Etiology

The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
Morandi P, Rouzier R, Altundag K, Buzdar AU, Theriault RL, Hortobagyi G
Cancer 2004 Oct 1;101(7):1482-9. doi: 10.1002/cncr.20522. PMID: 15378476
A randomized trial of tamoxifen alone or combined with octreotide in the treatment of women with metastatic breast carcinoma.
Ingle JN, Suman VJ, Kardinal CG, Krook JE, Mailliard JA, Veeder MH, Loprinzi CL, Dalton RJ, Hartmann LC, Conover CA, Pollak MN
Cancer 1999 Mar 15;85(6):1284-92. doi: 10.1002/(sici)1097-0142(19990315)85:6<1284::aid-cncr10>3.0.co;2-p. PMID: 10189133

Diagnosis

The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
Morandi P, Rouzier R, Altundag K, Buzdar AU, Theriault RL, Hortobagyi G
Cancer 2004 Oct 1;101(7):1482-9. doi: 10.1002/cncr.20522. PMID: 15378476

Therapy

Abemaciclib: safety and effectiveness of a unique cyclin-dependent kinase inhibitor.
Gebbia V, Valerio MR, Firenze A, Vigneri P
Expert Opin Drug Saf 2020 Aug;19(8):945-954. Epub 2020 Jun 22 doi: 10.1080/14740338.2020.1781814. PMID: 32552035
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
Morandi P, Rouzier R, Altundag K, Buzdar AU, Theriault RL, Hortobagyi G
Cancer 2004 Oct 1;101(7):1482-9. doi: 10.1002/cncr.20522. PMID: 15378476
A randomized trial of tamoxifen alone or combined with octreotide in the treatment of women with metastatic breast carcinoma.
Ingle JN, Suman VJ, Kardinal CG, Krook JE, Mailliard JA, Veeder MH, Loprinzi CL, Dalton RJ, Hartmann LC, Conover CA, Pollak MN
Cancer 1999 Mar 15;85(6):1284-92. doi: 10.1002/(sici)1097-0142(19990315)85:6<1284::aid-cncr10>3.0.co;2-p. PMID: 10189133

Prognosis

Age-related Differences in Spatially Resolved Transcriptomic Profiles of Patients With Hormone Receptor-positive Breast Carcinoma.
Chu J, DO SI, Kim HS
Anticancer Res 2024 Jun;44(6):2605-2616. doi: 10.21873/anticanres.17066. PMID: 38821623
Abemaciclib: safety and effectiveness of a unique cyclin-dependent kinase inhibitor.
Gebbia V, Valerio MR, Firenze A, Vigneri P
Expert Opin Drug Saf 2020 Aug;19(8):945-954. Epub 2020 Jun 22 doi: 10.1080/14740338.2020.1781814. PMID: 32552035
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
Morandi P, Rouzier R, Altundag K, Buzdar AU, Theriault RL, Hortobagyi G
Cancer 2004 Oct 1;101(7):1482-9. doi: 10.1002/cncr.20522. PMID: 15378476
A randomized trial of tamoxifen alone or combined with octreotide in the treatment of women with metastatic breast carcinoma.
Ingle JN, Suman VJ, Kardinal CG, Krook JE, Mailliard JA, Veeder MH, Loprinzi CL, Dalton RJ, Hartmann LC, Conover CA, Pollak MN
Cancer 1999 Mar 15;85(6):1284-92. doi: 10.1002/(sici)1097-0142(19990315)85:6<1284::aid-cncr10>3.0.co;2-p. PMID: 10189133
Induction of prostate specific antigen production by steroids and tamoxifen in breast cancer cell lines.
Yu H, Diamandis EP, Zarghami N, Grass L
Breast Cancer Res Treat 1994;32(3):291-300. doi: 10.1007/BF00666006. PMID: 7532467

Clinical prediction guides

Age-related Differences in Spatially Resolved Transcriptomic Profiles of Patients With Hormone Receptor-positive Breast Carcinoma.
Chu J, DO SI, Kim HS
Anticancer Res 2024 Jun;44(6):2605-2616. doi: 10.21873/anticanres.17066. PMID: 38821623
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
Morandi P, Rouzier R, Altundag K, Buzdar AU, Theriault RL, Hortobagyi G
Cancer 2004 Oct 1;101(7):1482-9. doi: 10.1002/cncr.20522. PMID: 15378476

Supplemental Content

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