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Urethral Melanoma

MedGen UID:
1685427
•Concept ID:
C5204612
•
Neoplastic Process

Definition

A rare melanoma that arises from the urethral mucosa. [from NCI]

Professional guidelines

PubMed

Outcome of surgical treatment for primary malignant melanoma of the female urethra.
DiMarco DS, DiMarco CS, Zincke H, Webb MJ, Keeney GL, Bass S, Lightner DJ
J Urol 2004 Feb;171(2 Pt 1):765-7. doi: 10.1097/01.ju.0000104671.20863.47. PMID: 14713806

Recent clinical studies

Etiology

Primary malignant melanoma of the urethra: Report of 9 cases in China.
Wang P, Huang Y, Chen B, Li J, Chen Z, Liu L
Asian J Surg 2024 Jan;47(1):505-512. Epub 2023 Jun 15 doi: 10.1016/j.asjsur.2023.05.113. PMID: 37330300
Mutational Profile in Vulvar, Vaginal, and Urethral Melanomas: Review of 37 Cases With Focus on Primary Tumor Site.
Zarei S, Voss JS, Jin L, Jenkins SM, Bryce AH, Erickson LA, Bell DA, Kipp BR, Flotte TJ
Int J Gynecol Pathol 2020 Nov;39(6):587-594. doi: 10.1097/PGP.0000000000000636. PMID: 31567539
Primary Urethral Melanoma: A Case Report and Literature Review.
Davuluri M, Long B, Semple S, Villanueva-Siles E, Aboumohamed A
Urology 2019 Apr;126:1-4. Epub 2018 Dec 31 doi: 10.1016/j.urology.2018.12.027. PMID: 30605694
Melanoma complicating treatment with natalizumab for multiple sclerosis: A report from the Southern Network on Adverse Reactions (SONAR).
Sabol RA, Noxon V, Sartor O, Berger JR, Qureshi Z, Raisch DW, Norris LB, Yarnold PR, Georgantopoulos P, Hrushesky WJ, Bobolts L, Ray P, Lebby A, Kane RC, Bennett CL
Cancer Med 2017 Jul;6(7):1541-1551. Epub 2017 Jun 20 doi: 10.1002/cam4.1098. PMID: 28635055Free PMC Article
Melanoma of the penis, scrotum and male urethra: a 40-year single institution experience.
Sánchez-Ortiz R, Huang SF, Tamboli P, Prieto VG, Hester G, Pettaway CA
J Urol 2005 Jun;173(6):1958-65. doi: 10.1097/01.ju.0000159207.91737.53. PMID: 15879790

Diagnosis

Malignant melanoma of urethra in a young female - Case report and Literature review.
Das J, Radhakrishna N, K G, A Badhe B
Gulf J Oncolog 2021 Jan;1(35):92-95. PMID: 33716219
Primary Urethral Melanoma: A Case Report and Literature Review.
Davuluri M, Long B, Semple S, Villanueva-Siles E, Aboumohamed A
Urology 2019 Apr;126:1-4. Epub 2018 Dec 31 doi: 10.1016/j.urology.2018.12.027. PMID: 30605694
Melanoma complicating treatment with natalizumab for multiple sclerosis: A report from the Southern Network on Adverse Reactions (SONAR).
Sabol RA, Noxon V, Sartor O, Berger JR, Qureshi Z, Raisch DW, Norris LB, Yarnold PR, Georgantopoulos P, Hrushesky WJ, Bobolts L, Ray P, Lebby A, Kane RC, Bennett CL
Cancer Med 2017 Jul;6(7):1541-1551. Epub 2017 Jun 20 doi: 10.1002/cam4.1098. PMID: 28635055Free PMC Article
Primary malignant melanoma of the urethra: a systematic analysis of the current literature.
El-Safadi S, Estel R, Mayser P, Muenstedt K
Arch Gynecol Obstet 2014 May;289(5):935-43. Epub 2013 Dec 27 doi: 10.1007/s00404-013-3130-3. PMID: 24370958
Melanoma of the female urethra.
Papeš D, Altarac S
Med Oncol 2013 Mar;30(1):329. Epub 2012 Dec 18 doi: 10.1007/s12032-012-0329-2. PMID: 23254965

Therapy

Melanoma complicating treatment with natalizumab for multiple sclerosis: A report from the Southern Network on Adverse Reactions (SONAR).
Sabol RA, Noxon V, Sartor O, Berger JR, Qureshi Z, Raisch DW, Norris LB, Yarnold PR, Georgantopoulos P, Hrushesky WJ, Bobolts L, Ray P, Lebby A, Kane RC, Bennett CL
Cancer Med 2017 Jul;6(7):1541-1551. Epub 2017 Jun 20 doi: 10.1002/cam4.1098. PMID: 28635055Free PMC Article
Malignant melanoma of the penis and male urethra.
Begun FP, Grossman HB, Diokno AC, Sogani PC
J Urol 1984 Jul;132(1):123-5. doi: 10.1016/s0022-5347(17)49495-x. PMID: 6726939

Prognosis

Primary mucosal melanomas of the urogenital tract: a clinical, pathological, and genetic nationwide survey of Danish patients 1990-2019.
Znaider VK, Mikkelsen LH, Jensen CFS, Sønksen J, Heegaard S
Scand J Urol 2023 Aug 27;58:52-59. doi: 10.2340/sju.v58.8489. PMID: 37635444
Malignant melanoma of urethra in a young female - Case report and Literature review.
Das J, Radhakrishna N, K G, A Badhe B
Gulf J Oncolog 2021 Jan;1(35):92-95. PMID: 33716219
Primary Urethral Melanoma: A Case Report and Literature Review.
Davuluri M, Long B, Semple S, Villanueva-Siles E, Aboumohamed A
Urology 2019 Apr;126:1-4. Epub 2018 Dec 31 doi: 10.1016/j.urology.2018.12.027. PMID: 30605694
Primary malignant melanoma of the urethra: a systematic analysis of the current literature.
El-Safadi S, Estel R, Mayser P, Muenstedt K
Arch Gynecol Obstet 2014 May;289(5):935-43. Epub 2013 Dec 27 doi: 10.1007/s00404-013-3130-3. PMID: 24370958
Melanoma of the female urethra.
Papeš D, Altarac S
Med Oncol 2013 Mar;30(1):329. Epub 2012 Dec 18 doi: 10.1007/s12032-012-0329-2. PMID: 23254965

Clinical prediction guides

Melanoma complicating treatment with natalizumab for multiple sclerosis: A report from the Southern Network on Adverse Reactions (SONAR).
Sabol RA, Noxon V, Sartor O, Berger JR, Qureshi Z, Raisch DW, Norris LB, Yarnold PR, Georgantopoulos P, Hrushesky WJ, Bobolts L, Ray P, Lebby A, Kane RC, Bennett CL
Cancer Med 2017 Jul;6(7):1541-1551. Epub 2017 Jun 20 doi: 10.1002/cam4.1098. PMID: 28635055Free PMC Article
Primary malignant melanoma of the urethra: a systematic analysis of the current literature.
El-Safadi S, Estel R, Mayser P, Muenstedt K
Arch Gynecol Obstet 2014 May;289(5):935-43. Epub 2013 Dec 27 doi: 10.1007/s00404-013-3130-3. PMID: 24370958

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