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Stage IIA2 Cervical Cancer FIGO 2018

MedGen UID:
1687162
•Concept ID:
C5206446
•
Neoplastic Process
Synonym: Stage IIA2 Cervical Carcinoma FIGO 2018

Definition

Cervical carcinoma limited to the upper two-thirds of the vagina without parametrial involvement, equal or more than 4 cm in greatest dimension. (FIGO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage IIA2 Cervical Cancer FIGO 2018

Professional guidelines

PubMed

Prognosis and treatment regimens for patients with different lymph node statuses in locally advanced cervical cancer.
Guo W, Ren R, Li N, Hu Y
Eur J Surg Oncol 2024 Nov;50(11):108522. Epub 2024 Jun 29 doi: 10.1016/j.ejso.2024.108522. PMID: 39255585

Recent clinical studies

Etiology

The prognostic value of the presence of pelvic and/or para-aortic lymph node metastases in cervical cancer patients; the influence of the new FIGO classification (stage IIIC).
van Kol KGG, Ebisch RMF, van der Aa M, Wenzel HB, Piek JMJ, Bekkers RLM
Gynecol Oncol 2023 Apr;171:9-14. Epub 2023 Feb 16 doi: 10.1016/j.ygyno.2023.01.023. PMID: 36804623
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Clinical outcome of FIGO 2018 stage IB3/IIA2 cervical cancer treated by neoadjuvant chemotherapy followed by radical surgery due to lack of radiotherapy equipment: A retrospective comparison with concurrent chemoradiotherapy.
Zeng J, Sun P, Ping Q, Jiang S, Hu Y
PLoS One 2022;17(3):e0266001. Epub 2022 Mar 24 doi: 10.1371/journal.pone.0266001. PMID: 35324998Free PMC Article
Adjuvant hysterectomy following primary chemoradiation for stage IB2 and IIA2 cervical cancer: a retrospective comparison of complications for open versus minimally invasive surgery.
Miller H, Matsuo K, Roman LD, Yessaian AA, Pham HQ, Hom M, Castaneda A, Pham A, Ragab O, Muderspach L, Ciccone M, Brunette LL
Radiat Oncol 2021 Jun 29;16(1):123. doi: 10.1186/s13014-021-01843-0. PMID: 34187504Free PMC Article
Characteristics, complications, and outcomes of early-stage cervical stump carcinoma: laparoscopy versus laparotomy.
Lu Z, Guo C, Wang T, Qiu J, Hua K
J Int Med Res 2021 Feb;49(2):300060521992247. doi: 10.1177/0300060521992247. PMID: 33641455Free PMC Article

Diagnosis

Comparison between laparoscopic and abdominal radical hysterectomy for cervical adenosquamous carcinoma at stage IA2 to IIA2: A multicenter retrospective study.
Teng X, Kang S, Li W, Ding H, Ling B, Zhu L, Wang D, Lang J, Liu P, Chen C
J Obstet Gynaecol Res 2023 Jun;49(6):1592-1610. Epub 2023 Mar 14 doi: 10.1111/jog.15633. PMID: 36919234
The prognostic value of the presence of pelvic and/or para-aortic lymph node metastases in cervical cancer patients; the influence of the new FIGO classification (stage IIIC).
van Kol KGG, Ebisch RMF, van der Aa M, Wenzel HB, Piek JMJ, Bekkers RLM
Gynecol Oncol 2023 Apr;171:9-14. Epub 2023 Feb 16 doi: 10.1016/j.ygyno.2023.01.023. PMID: 36804623
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Comparison of survival outcomes of abdominal radical hysterectomy and radiochemotherapy IIA2 (FIGO2018) cervical cancer: a retrospective study from a large database of 63,926 cases of cervical cancer in China.
He J, Li D, Shen P, Liang W, Kang S, Zhang Y, Zhao H, Liu M, Wang X, Lin Z, Bin X, Lang J, Liu P, Chen C
Int J Clin Oncol 2022 Mar;27(3):619-625. Epub 2021 Nov 27 doi: 10.1007/s10147-021-02090-9. PMID: 34837596
Re-classification of uterine cervical cancer cases treated with radical hysterectomy based on the 2018 FIGO staging system.
Osaku D, Komatsu H, Okawa M, Iida Y, Sato S, Oishi T, Harada T
Taiwan J Obstet Gynecol 2021 Nov;60(6):1054-1058. doi: 10.1016/j.tjog.2021.09.016. PMID: 34794737

Therapy

Evaluating the clinical efficacy and safety of concurrent chemoradiotherapy with cisplatin and nab-paclitaxel in postoperative early-stage cervical cancer.
Zhao N, Li Y, Chen X, Ma J, Luo W, Li Y
J Cancer Res Clin Oncol 2024 May 6;150(5):233. doi: 10.1007/s00432-024-05764-9. PMID: 38709400Free PMC Article
Dose-dense neoadjuvant chemotherapy before radical surgery in cervical cancer: a retrospective cohort study and systematic literature review.
Caruso G, Bruni S, Lapresa M, De Vitis LA, Parma G, Minicucci V, Betella I, Schivardi G, Peccatori F, Lazzari R, Cliby W, Aletti GD, Zanagnolo V, Maggioni A, Colombo N, Multinu F
Int J Gynecol Cancer 2024 Jan 5;34(1):47-57. doi: 10.1136/ijgc-2023-004928. PMID: 37949488
Clinical outcome of FIGO 2018 stage IB3/IIA2 cervical cancer treated by neoadjuvant chemotherapy followed by radical surgery due to lack of radiotherapy equipment: A retrospective comparison with concurrent chemoradiotherapy.
Zeng J, Sun P, Ping Q, Jiang S, Hu Y
PLoS One 2022;17(3):e0266001. Epub 2022 Mar 24 doi: 10.1371/journal.pone.0266001. PMID: 35324998Free PMC Article
Comparison of survival outcomes of abdominal radical hysterectomy and radiochemotherapy IIA2 (FIGO2018) cervical cancer: a retrospective study from a large database of 63,926 cases of cervical cancer in China.
He J, Li D, Shen P, Liang W, Kang S, Zhang Y, Zhao H, Liu M, Wang X, Lin Z, Bin X, Lang J, Liu P, Chen C
Int J Clin Oncol 2022 Mar;27(3):619-625. Epub 2021 Nov 27 doi: 10.1007/s10147-021-02090-9. PMID: 34837596
Characteristics, complications, and outcomes of early-stage cervical stump carcinoma: laparoscopy versus laparotomy.
Lu Z, Guo C, Wang T, Qiu J, Hua K
J Int Med Res 2021 Feb;49(2):300060521992247. doi: 10.1177/0300060521992247. PMID: 33641455Free PMC Article

Prognosis

Comparison between laparoscopic and abdominal radical hysterectomy for cervical adenosquamous carcinoma at stage IA2 to IIA2: A multicenter retrospective study.
Teng X, Kang S, Li W, Ding H, Ling B, Zhu L, Wang D, Lang J, Liu P, Chen C
J Obstet Gynaecol Res 2023 Jun;49(6):1592-1610. Epub 2023 Mar 14 doi: 10.1111/jog.15633. PMID: 36919234
The prognostic value of the presence of pelvic and/or para-aortic lymph node metastases in cervical cancer patients; the influence of the new FIGO classification (stage IIIC).
van Kol KGG, Ebisch RMF, van der Aa M, Wenzel HB, Piek JMJ, Bekkers RLM
Gynecol Oncol 2023 Apr;171:9-14. Epub 2023 Feb 16 doi: 10.1016/j.ygyno.2023.01.023. PMID: 36804623
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Adjuvant hysterectomy following primary chemoradiation for stage IB2 and IIA2 cervical cancer: a retrospective comparison of complications for open versus minimally invasive surgery.
Miller H, Matsuo K, Roman LD, Yessaian AA, Pham HQ, Hom M, Castaneda A, Pham A, Ragab O, Muderspach L, Ciccone M, Brunette LL
Radiat Oncol 2021 Jun 29;16(1):123. doi: 10.1186/s13014-021-01843-0. PMID: 34187504Free PMC Article
A novel prognostic nomogram utilizing the 2018 FIGO staging system for cervical cancer: A large multicenter study.
Tang X, Guo C, Liu S, Guo J, Hua K, Qiu J
Int J Gynaecol Obstet 2021 Oct;155(1):86-94. Epub 2021 May 3 doi: 10.1002/ijgo.13644. PMID: 33587753

Clinical prediction guides

Comparison between laparoscopic and abdominal radical hysterectomy for cervical adenosquamous carcinoma at stage IA2 to IIA2: A multicenter retrospective study.
Teng X, Kang S, Li W, Ding H, Ling B, Zhu L, Wang D, Lang J, Liu P, Chen C
J Obstet Gynaecol Res 2023 Jun;49(6):1592-1610. Epub 2023 Mar 14 doi: 10.1111/jog.15633. PMID: 36919234
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Comparison of survival outcomes of abdominal radical hysterectomy and radiochemotherapy IIA2 (FIGO2018) cervical cancer: a retrospective study from a large database of 63,926 cases of cervical cancer in China.
He J, Li D, Shen P, Liang W, Kang S, Zhang Y, Zhao H, Liu M, Wang X, Lin Z, Bin X, Lang J, Liu P, Chen C
Int J Clin Oncol 2022 Mar;27(3):619-625. Epub 2021 Nov 27 doi: 10.1007/s10147-021-02090-9. PMID: 34837596
Re-classification of uterine cervical cancer cases treated with radical hysterectomy based on the 2018 FIGO staging system.
Osaku D, Komatsu H, Okawa M, Iida Y, Sato S, Oishi T, Harada T
Taiwan J Obstet Gynecol 2021 Nov;60(6):1054-1058. doi: 10.1016/j.tjog.2021.09.016. PMID: 34794737
A novel prognostic nomogram utilizing the 2018 FIGO staging system for cervical cancer: A large multicenter study.
Tang X, Guo C, Liu S, Guo J, Hua K, Qiu J
Int J Gynaecol Obstet 2021 Oct;155(1):86-94. Epub 2021 May 3 doi: 10.1002/ijgo.13644. PMID: 33587753

Recent systematic reviews

Dose-dense neoadjuvant chemotherapy before radical surgery in cervical cancer: a retrospective cohort study and systematic literature review.
Caruso G, Bruni S, Lapresa M, De Vitis LA, Parma G, Minicucci V, Betella I, Schivardi G, Peccatori F, Lazzari R, Cliby W, Aletti GD, Zanagnolo V, Maggioni A, Colombo N, Multinu F
Int J Gynecol Cancer 2024 Jan 5;34(1):47-57. doi: 10.1136/ijgc-2023-004928. PMID: 37949488

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    • Stage IIA2 Cervical Cancer FIGO 2018
      Stage IIA2 Cervical Cancer FIGO 2018
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