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Refractory Kidney Medullary Carcinoma

MedGen UID:
1695151
Concept ID:
C5206775
Neoplastic Process

Definition

A kidney medullary carcinoma that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Kidney Medullary Carcinoma

Professional guidelines

PubMed

Li S, Wang H
Drug Des Devel Ther 2023;17:3429-3437. Epub 2023 Nov 15 doi: 10.2147/DDDT.S426898. PMID: 38024530Free PMC Article
Msaouel P, Hong AL, Mullen EA, Atkins MB, Walker CL, Lee CH, Carden MA, Genovese G, Linehan WM, Rao P, Merino MJ, Grodman H, Dome JS, Fernandez CV, Geller JI, Apolo AB, Daw NC, Hodges HC, Moxey-Mims M, Wei D, Bottaro DP, Staehler M, Karam JA, Rathmell WK, Tannir NM
Clin Genitourin Cancer 2019 Feb;17(1):1-6. Epub 2018 Sep 12 doi: 10.1016/j.clgc.2018.09.005. PMID: 30287223Free PMC Article
Sarlis NJ, Gourgiotis L
Curr Drug Targets Immune Endocr Metabol Disord 2004 Sep;4(3):187-98. doi: 10.2174/1568008043339866. PMID: 15379722

Recent clinical studies

Etiology

Kotecha RR, Doshi SD, Knezevic A, Chaim J, Chen Y, Jacobi R, Zucker M, Reznik E, McHugh D, Shah NJ, Feld E, Aggen DH, Rafelson W, Xiao H, Carlo MI, Feldman DR, Lee CH, Motzer RJ, Voss MH
Eur Urol Oncol 2024 Aug;7(4):804-811. Epub 2023 Nov 7 doi: 10.1016/j.euo.2023.10.017. PMID: 37945488Free PMC Article
Soeung M, Perelli L, Chen Z, Dondossola E, Ho IL, Carbone F, Zhang L, Khan H, Le CN, Zhu C, Peoples MD, Feng N, Jiang S, Zacharias NM, Minelli R, Shapiro DD, Deem AK, Gao S, Cheng EH, Lucchetti D, Walker CL, Carugo A, Giuliani V, Heffernan TP, Viale A, Tannir NM, Draetta GF, Msaouel P, Genovese G
Proc Natl Acad Sci U S A 2023 May 23;120(21):e2209639120. Epub 2023 May 15 doi: 10.1073/pnas.2209639120. PMID: 37186844Free PMC Article
Wilson NR, Wiele AJ, Surasi DS, Rao P, Sircar K, Tamboli P, Shah AY, Genovese G, Karam JA, Wood CG, Tannir NM, Msaouel P
Clin Genitourin Cancer 2021 Dec;19(6):e401-e408. Epub 2021 Sep 15 doi: 10.1016/j.clgc.2021.08.007. PMID: 34625389

Diagnosis

Soeung M, Perelli L, Chen Z, Dondossola E, Ho IL, Carbone F, Zhang L, Khan H, Le CN, Zhu C, Peoples MD, Feng N, Jiang S, Zacharias NM, Minelli R, Shapiro DD, Deem AK, Gao S, Cheng EH, Lucchetti D, Walker CL, Carugo A, Giuliani V, Heffernan TP, Viale A, Tannir NM, Draetta GF, Msaouel P, Genovese G
Proc Natl Acad Sci U S A 2023 May 23;120(21):e2209639120. Epub 2023 May 15 doi: 10.1073/pnas.2209639120. PMID: 37186844Free PMC Article
Gubbi S, Koch CA, Klubo-Gwiezdzinska J
Front Endocrinol (Lausanne) 2022;13:896287. Epub 2022 May 30 doi: 10.3389/fendo.2022.896287. PMID: 35712243Free PMC Article
Wilson NR, Wiele AJ, Surasi DS, Rao P, Sircar K, Tamboli P, Shah AY, Genovese G, Karam JA, Wood CG, Tannir NM, Msaouel P
Clin Genitourin Cancer 2021 Dec;19(6):e401-e408. Epub 2021 Sep 15 doi: 10.1016/j.clgc.2021.08.007. PMID: 34625389
Msaouel P, Hong AL, Mullen EA, Atkins MB, Walker CL, Lee CH, Carden MA, Genovese G, Linehan WM, Rao P, Merino MJ, Grodman H, Dome JS, Fernandez CV, Geller JI, Apolo AB, Daw NC, Hodges HC, Moxey-Mims M, Wei D, Bottaro DP, Staehler M, Karam JA, Rathmell WK, Tannir NM
Clin Genitourin Cancer 2019 Feb;17(1):1-6. Epub 2018 Sep 12 doi: 10.1016/j.clgc.2018.09.005. PMID: 30287223Free PMC Article
Pirich LM, Chou P, Walterhouse DO
J Pediatr Hematol Oncol 1999 Jan-Feb;21(1):67-9. PMID: 10029817

Therapy

Kotecha RR, Doshi SD, Knezevic A, Chaim J, Chen Y, Jacobi R, Zucker M, Reznik E, McHugh D, Shah NJ, Feld E, Aggen DH, Rafelson W, Xiao H, Carlo MI, Feldman DR, Lee CH, Motzer RJ, Voss MH
Eur Urol Oncol 2024 Aug;7(4):804-811. Epub 2023 Nov 7 doi: 10.1016/j.euo.2023.10.017. PMID: 37945488Free PMC Article
Li S, Wang H
Drug Des Devel Ther 2023;17:3429-3437. Epub 2023 Nov 15 doi: 10.2147/DDDT.S426898. PMID: 38024530Free PMC Article
Gubbi S, Koch CA, Klubo-Gwiezdzinska J
Front Endocrinol (Lausanne) 2022;13:896287. Epub 2022 May 30 doi: 10.3389/fendo.2022.896287. PMID: 35712243Free PMC Article
Wilson NR, Wiele AJ, Surasi DS, Rao P, Sircar K, Tamboli P, Shah AY, Genovese G, Karam JA, Wood CG, Tannir NM, Msaouel P
Clin Genitourin Cancer 2021 Dec;19(6):e401-e408. Epub 2021 Sep 15 doi: 10.1016/j.clgc.2021.08.007. PMID: 34625389
Chow LQ, Eckhardt SG
J Clin Oncol 2007 Mar 1;25(7):884-96. doi: 10.1200/JCO.2006.06.3602. PMID: 17327610

Prognosis

Msaouel P, Hong AL, Mullen EA, Atkins MB, Walker CL, Lee CH, Carden MA, Genovese G, Linehan WM, Rao P, Merino MJ, Grodman H, Dome JS, Fernandez CV, Geller JI, Apolo AB, Daw NC, Hodges HC, Moxey-Mims M, Wei D, Bottaro DP, Staehler M, Karam JA, Rathmell WK, Tannir NM
Clin Genitourin Cancer 2019 Feb;17(1):1-6. Epub 2018 Sep 12 doi: 10.1016/j.clgc.2018.09.005. PMID: 30287223Free PMC Article
Brown JM, Berkey BD, Brooks JA
Clin Nucl Med 2008 Dec;33(12):896-900. doi: 10.1097/RLU.0b013e31818bf31d. PMID: 19033803
Pirich LM, Chou P, Walterhouse DO
J Pediatr Hematol Oncol 1999 Jan-Feb;21(1):67-9. PMID: 10029817

Clinical prediction guides

Soeung M, Perelli L, Chen Z, Dondossola E, Ho IL, Carbone F, Zhang L, Khan H, Le CN, Zhu C, Peoples MD, Feng N, Jiang S, Zacharias NM, Minelli R, Shapiro DD, Deem AK, Gao S, Cheng EH, Lucchetti D, Walker CL, Carugo A, Giuliani V, Heffernan TP, Viale A, Tannir NM, Draetta GF, Msaouel P, Genovese G
Proc Natl Acad Sci U S A 2023 May 23;120(21):e2209639120. Epub 2023 May 15 doi: 10.1073/pnas.2209639120. PMID: 37186844Free PMC Article

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