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Stage IVB Cervical Cancer FIGO 2018

MedGen UID:
1700707
•Concept ID:
C5206456
•
Neoplastic Process
Synonym: Stage IVB Cervical Carcinoma FIGO 2018

Definition

The cervical carcinoma has spread to distant organs. (FIGO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage IVB Cervical Cancer FIGO 2018

Professional guidelines

PubMed

Definitive irradiation as a first treatment strategy for primary and metastatic sites of newly diagnosed IVB cervical cancer that presented with synchronous oligometastases.
Li J, Wang Y, Huo L, Huang X, Shi L, Huang L, Chen K, Cao X
Radiat Oncol 2023 Sep 26;18(1):159. doi: 10.1186/s13014-023-02320-6. PMID: 37752606Free PMC Article
Establishment of a risk stratification model based on the combination of post-treatment serum squamous cell carcinoma antigen levels and FIGO stage of cervical cancer for treatment and surveillance decision-making.
Shi L, Liu Y, Li J, Kou J, Ouyang Y, Chen F, Huang X, Huo L, Huang L, Cao X
J Cancer Res Clin Oncol 2023 Aug;149(9):5999-6007. Epub 2023 Jan 9 doi: 10.1007/s00432-022-04558-1. PMID: 36624190Free PMC Article
Increasing age predicts poor cervical cancer prognosis with subsequent effect on treatment and overall survival.
Quinn BA, Deng X, Colton A, Bandyopadhyay D, Carter JS, Fields EC
Brachytherapy 2019 Jan-Feb;18(1):29-37. Epub 2018 Oct 22 doi: 10.1016/j.brachy.2018.08.016. PMID: 30361045Free PMC Article

Recent clinical studies

Etiology

Population-Based Survival Analysis of Stage IVB Small-Cell Neuroendocrine Carcinoma in Comparison to Major Histological Subtypes of Cervical Cancer.
Mabuchi S, Komura N, Sasano T, Sakata M, Matsuzaki S, Hisa T, Kamiura S, Morishima T, Miyashiro I
Curr Oncol 2023 Oct 24;30(11):9428-9436. doi: 10.3390/curroncol30110682. PMID: 37999102Free PMC Article
Definitive irradiation as a first treatment strategy for primary and metastatic sites of newly diagnosed IVB cervical cancer that presented with synchronous oligometastases.
Li J, Wang Y, Huo L, Huang X, Shi L, Huang L, Chen K, Cao X
Radiat Oncol 2023 Sep 26;18(1):159. doi: 10.1186/s13014-023-02320-6. PMID: 37752606Free PMC Article
Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: a systematic review.
Viveros-Carreño D, Vieira-Serna S, Grillo-Ardila CF, Rodriguez J, Mora-Soto N, Jhingran A, Ramirez PT, Pareja R
Int J Gynecol Cancer 2023 Jul 3;33(7):1057-1062. doi: 10.1136/ijgc-2023-004465. PMID: 37192760
Definitive pelvic radiation therapy improves survival in stage IVB neuroendocrine cervical carcinoma: A NeCTuR study.
Salvo G, Jhingran A, Ramalingam P, Legarreta AF, Bhosale P, Gonzales NR, Chisholm GB, Frumovitz M
Gynecol Oncol 2022 Jun;165(3):530-537. Epub 2022 Apr 5 doi: 10.1016/j.ygyno.2022.03.022. PMID: 35396134Free PMC Article
Diagnosis of advanced cervical cancer, missed opportunities?
Mattern J, Letendre I, Sibiude J, Pénager C, Jnifen A, Souare F, Ayel S, Nguyen T, Mandelbrot L
BMC Womens Health 2022 Mar 30;22(1):97. doi: 10.1186/s12905-022-01668-3. PMID: 35354463Free PMC Article

Diagnosis

Prognostic value of (18)F-FDG PET in uterine cervical cancer patients with stage IIICr allocated by imaging.
Isaji Y, Tsuyoshi H, Tsujikawa T, Orisaka M, Okazawa H, Yoshida Y
Sci Rep 2023 Nov 1;13(1):18864. doi: 10.1038/s41598-023-46261-2. PMID: 37914892Free PMC Article
Definitive irradiation as a first treatment strategy for primary and metastatic sites of newly diagnosed IVB cervical cancer that presented with synchronous oligometastases.
Li J, Wang Y, Huo L, Huang X, Shi L, Huang L, Chen K, Cao X
Radiat Oncol 2023 Sep 26;18(1):159. doi: 10.1186/s13014-023-02320-6. PMID: 37752606Free PMC Article
Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: a systematic review.
Viveros-Carreño D, Vieira-Serna S, Grillo-Ardila CF, Rodriguez J, Mora-Soto N, Jhingran A, Ramirez PT, Pareja R
Int J Gynecol Cancer 2023 Jul 3;33(7):1057-1062. doi: 10.1136/ijgc-2023-004465. PMID: 37192760
Definitive pelvic radiation therapy improves survival in stage IVB neuroendocrine cervical carcinoma: A NeCTuR study.
Salvo G, Jhingran A, Ramalingam P, Legarreta AF, Bhosale P, Gonzales NR, Chisholm GB, Frumovitz M
Gynecol Oncol 2022 Jun;165(3):530-537. Epub 2022 Apr 5 doi: 10.1016/j.ygyno.2022.03.022. PMID: 35396134Free PMC Article
Diagnosis of advanced cervical cancer, missed opportunities?
Mattern J, Letendre I, Sibiude J, Pénager C, Jnifen A, Souare F, Ayel S, Nguyen T, Mandelbrot L
BMC Womens Health 2022 Mar 30;22(1):97. doi: 10.1186/s12905-022-01668-3. PMID: 35354463Free PMC Article

Therapy

Pegylated recombinant human granulocyte colony-stimulating factor for primary prophylaxis of neutropenia in patients with cervical cancer receiving concurrent chemoradiotherapy: a prospective study.
You J, Yuan Y, Gu X, Wang W, Li X
BMC Cancer 2024 Jul 12;24(1):833. doi: 10.1186/s12885-024-12556-4. PMID: 38997665Free PMC Article
The Efficacy of Volumetric Modulated Arc Therapy Combined With Chemotherapy, Brachytherapy, and Local Hyperthermia on Patients with Locally Advanced Cervical Cancer: A Retrospective Study.
Jiang P, Wei S, Bai Y, Qu A, Jiang W, Sun H, Wang J
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338231185013. doi: 10.1177/15330338231185013. PMID: 37357685Free PMC Article
Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: a systematic review.
Viveros-Carreño D, Vieira-Serna S, Grillo-Ardila CF, Rodriguez J, Mora-Soto N, Jhingran A, Ramirez PT, Pareja R
Int J Gynecol Cancer 2023 Jul 3;33(7):1057-1062. doi: 10.1136/ijgc-2023-004465. PMID: 37192760
The importance of choosing the right strategy to treat small cell carcinoma of the cervix: a comparative analysis of treatments.
Kawamura M, Koide Y, Murai T, Ishihara S, Takase Y, Murao T, Okazaki D, Yamaguchi T, Uchiyama K, Itoh Y, Kodaira T, Shibamoto Y, Mizuno M, Kikkawa F, Naganawa S
BMC Cancer 2021 Sep 23;21(1):1046. doi: 10.1186/s12885-021-08772-x. PMID: 34556082Free PMC Article

Prognosis

Population-Based Survival Analysis of Stage IVB Small-Cell Neuroendocrine Carcinoma in Comparison to Major Histological Subtypes of Cervical Cancer.
Mabuchi S, Komura N, Sasano T, Sakata M, Matsuzaki S, Hisa T, Kamiura S, Morishima T, Miyashiro I
Curr Oncol 2023 Oct 24;30(11):9428-9436. doi: 10.3390/curroncol30110682. PMID: 37999102Free PMC Article
Prognostic value of (18)F-FDG PET in uterine cervical cancer patients with stage IIICr allocated by imaging.
Isaji Y, Tsuyoshi H, Tsujikawa T, Orisaka M, Okazawa H, Yoshida Y
Sci Rep 2023 Nov 1;13(1):18864. doi: 10.1038/s41598-023-46261-2. PMID: 37914892Free PMC Article
Definitive irradiation as a first treatment strategy for primary and metastatic sites of newly diagnosed IVB cervical cancer that presented with synchronous oligometastases.
Li J, Wang Y, Huo L, Huang X, Shi L, Huang L, Chen K, Cao X
Radiat Oncol 2023 Sep 26;18(1):159. doi: 10.1186/s13014-023-02320-6. PMID: 37752606Free PMC Article
Establishment of a risk stratification model based on the combination of post-treatment serum squamous cell carcinoma antigen levels and FIGO stage of cervical cancer for treatment and surveillance decision-making.
Shi L, Liu Y, Li J, Kou J, Ouyang Y, Chen F, Huang X, Huo L, Huang L, Cao X
J Cancer Res Clin Oncol 2023 Aug;149(9):5999-6007. Epub 2023 Jan 9 doi: 10.1007/s00432-022-04558-1. PMID: 36624190Free PMC Article
Definitive pelvic radiation therapy improves survival in stage IVB neuroendocrine cervical carcinoma: A NeCTuR study.
Salvo G, Jhingran A, Ramalingam P, Legarreta AF, Bhosale P, Gonzales NR, Chisholm GB, Frumovitz M
Gynecol Oncol 2022 Jun;165(3):530-537. Epub 2022 Apr 5 doi: 10.1016/j.ygyno.2022.03.022. PMID: 35396134Free PMC Article

Clinical prediction guides

Population-Based Survival Analysis of Stage IVB Small-Cell Neuroendocrine Carcinoma in Comparison to Major Histological Subtypes of Cervical Cancer.
Mabuchi S, Komura N, Sasano T, Sakata M, Matsuzaki S, Hisa T, Kamiura S, Morishima T, Miyashiro I
Curr Oncol 2023 Oct 24;30(11):9428-9436. doi: 10.3390/curroncol30110682. PMID: 37999102Free PMC Article
Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: a systematic review.
Viveros-Carreño D, Vieira-Serna S, Grillo-Ardila CF, Rodriguez J, Mora-Soto N, Jhingran A, Ramirez PT, Pareja R
Int J Gynecol Cancer 2023 Jul 3;33(7):1057-1062. doi: 10.1136/ijgc-2023-004465. PMID: 37192760
Establishment of a risk stratification model based on the combination of post-treatment serum squamous cell carcinoma antigen levels and FIGO stage of cervical cancer for treatment and surveillance decision-making.
Shi L, Liu Y, Li J, Kou J, Ouyang Y, Chen F, Huang X, Huo L, Huang L, Cao X
J Cancer Res Clin Oncol 2023 Aug;149(9):5999-6007. Epub 2023 Jan 9 doi: 10.1007/s00432-022-04558-1. PMID: 36624190Free PMC Article
Diagnosis of advanced cervical cancer, missed opportunities?
Mattern J, Letendre I, Sibiude J, Pénager C, Jnifen A, Souare F, Ayel S, Nguyen T, Mandelbrot L
BMC Womens Health 2022 Mar 30;22(1):97. doi: 10.1186/s12905-022-01668-3. PMID: 35354463Free PMC Article
Increasing age predicts poor cervical cancer prognosis with subsequent effect on treatment and overall survival.
Quinn BA, Deng X, Colton A, Bandyopadhyay D, Carter JS, Fields EC
Brachytherapy 2019 Jan-Feb;18(1):29-37. Epub 2018 Oct 22 doi: 10.1016/j.brachy.2018.08.016. PMID: 30361045Free PMC Article

Recent systematic reviews

Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: a systematic review.
Viveros-Carreño D, Vieira-Serna S, Grillo-Ardila CF, Rodriguez J, Mora-Soto N, Jhingran A, Ramirez PT, Pareja R
Int J Gynecol Cancer 2023 Jul 3;33(7):1057-1062. doi: 10.1136/ijgc-2023-004465. PMID: 37192760

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