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Stage IV Cervical Cancer FIGO 2018

MedGen UID:
1703925
•Concept ID:
C5206454
•
Neoplastic Process
Synonym: Stage IV Cervical Carcinoma FIGO 2018

Definition

The cervical carcinoma has extended beyond the true pelvis or has involved (biopsy proven) the mucosa of the bladder or rectum. (A bullous edema, as such, does not permit a case to be allotted to Stage IV). (FIGO 2018) [from NCI]

Professional guidelines

PubMed

Combination of weekly paclitaxel-carboplatin plus standard bevacizumab as neoadjuvant treatment in stage IB-IIB cervical cancer.
Maene C, Salihi RR, Van Nieuwenhuysen E, Han SN, Concin N, Vergote I
Int J Gynecol Cancer 2021 Jun;31(6):824-828. Epub 2021 Apr 15 doi: 10.1136/ijgc-2021-002432. PMID: 33858952
FIGO 2018 staging criteria for cervical cancer: Impact on stage migration and survival.
Grigsby PW, Massad LS, Mutch DG, Powell MA, Thaker PH, McCourt C, Hagemann A, Fuh K, Kuroki L, Schwarz JK, Markovina S, Lin AJ, Dehdashti F, Siegel BA
Gynecol Oncol 2020 Jun;157(3):639-643. Epub 2020 Apr 2 doi: 10.1016/j.ygyno.2020.03.027. PMID: 32248993
Human papillomavirus genotype and prognosis of cervical cancer: Favorable survival of patients with HPV16-positive tumors.
Onuki M, Matsumoto K, Tenjimbayashi Y, Tasaka N, Akiyama A, Sakurai M, Minaguchi T, Oki A, Satoh T, Yoshikawa H
Papillomavirus Res 2018 Dec;6:41-45. Epub 2018 Oct 19 doi: 10.1016/j.pvr.2018.10.005. PMID: 30347290Free PMC Article

Recent clinical studies

Etiology

MRI-based radiomic signatures for pretreatment prognostication in cervical cancer.
Wagner-Larsen KS, Hodneland E, Fasmer KE, Lura N, Woie K, Bertelsen BI, Salvesen Ø, Halle MK, Smit N, Krakstad C, Haldorsen IS
Cancer Med 2023 Oct;12(20):20251-20265. Epub 2023 Oct 16 doi: 10.1002/cam4.6526. PMID: 37840437Free PMC Article
Clinical significance of MATN1-AS1 as ceRNA of Mir-200b in tissues and serum of patients with cervical cancer.
He L, Li P, Zhang H
Sci Rep 2023 Sep 15;13(1):15336. doi: 10.1038/s41598-023-42023-2. PMID: 37714866Free PMC Article
Establishment of a risk stratification model based on the combination of post-treatment serum squamous cell carcinoma antigen levels and FIGO stage of cervical cancer for treatment and surveillance decision-making.
Shi L, Liu Y, Li J, Kou J, Ouyang Y, Chen F, Huang X, Huo L, Huang L, Cao X
J Cancer Res Clin Oncol 2023 Aug;149(9):5999-6007. Epub 2023 Jan 9 doi: 10.1007/s00432-022-04558-1. PMID: 36624190Free PMC Article
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Level of human development is associated with cervical cancer stage at diagnosis.
Vale DB, Sauvaget C, Muwonge R, Thuler LCS, Basu P, Zeferino LC, Sankaranarayanan R
J Obstet Gynaecol 2019 Jan;39(1):86-90. Epub 2018 Sep 19 doi: 10.1080/01443615.2018.1463976. PMID: 30229689

Diagnosis

Systematic assessment of tumor necrosis at baseline in cervical cancer - An independent factor associated with poor outcome.
Chouchane-Mlik O, Oniga A, Latouche A, Halladjian M, Kleine-Borgmann FB, Gérardy JJ, Mittelbronn M, Kamal M, Scholl SM
Hum Pathol 2024 Jan;143:62-70. Epub 2023 Dec 20 doi: 10.1016/j.humpath.2023.12.003. PMID: 38135059
Barriers to early diagnosis of cervical cancer: a mixed-method study in Côte d'Ivoire, West Africa.
Plaisy MK, Boni SP, Coffie PA, Tanon A, Innocent A, Horo A, Dabis F, Bekelynck A, Jaquet A; IeDEA West Africa Collaboration
BMC Womens Health 2023 Mar 27;23(1):135. doi: 10.1186/s12905-023-02264-9. PMID: 36973736Free PMC Article
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
FIGO 2018 staging criteria for cervical cancer: Impact on stage migration and survival.
Grigsby PW, Massad LS, Mutch DG, Powell MA, Thaker PH, McCourt C, Hagemann A, Fuh K, Kuroki L, Schwarz JK, Markovina S, Lin AJ, Dehdashti F, Siegel BA
Gynecol Oncol 2020 Jun;157(3):639-643. Epub 2020 Apr 2 doi: 10.1016/j.ygyno.2020.03.027. PMID: 32248993
Level of human development is associated with cervical cancer stage at diagnosis.
Vale DB, Sauvaget C, Muwonge R, Thuler LCS, Basu P, Zeferino LC, Sankaranarayanan R
J Obstet Gynaecol 2019 Jan;39(1):86-90. Epub 2018 Sep 19 doi: 10.1080/01443615.2018.1463976. PMID: 30229689

Therapy

Impact of HIV infection on access to cancer care and survival among women with invasive cervical cancer in Côte d'Ivoire: A prospective cohort study.
Boni SP, Horo A, Didi-Kouko-Coulibaly J, Tanon A, Tchounga BK, Coffie PA, Comoe JC, Moh RD, Dabis F, Adoubi I, Jaquet A; IeDEA West Africa Collaboration
Int J Gynaecol Obstet 2023 Nov;163(2):392-401. Epub 2023 Jun 22 doi: 10.1002/ijgo.14925. PMID: 37350012Free PMC Article
Combination of weekly paclitaxel-carboplatin plus standard bevacizumab as neoadjuvant treatment in stage IB-IIB cervical cancer.
Maene C, Salihi RR, Van Nieuwenhuysen E, Han SN, Concin N, Vergote I
Int J Gynecol Cancer 2021 Jun;31(6):824-828. Epub 2021 Apr 15 doi: 10.1136/ijgc-2021-002432. PMID: 33858952
An analysis of HER2 amplification in cervical adenocarcinoma: correlation with clinical outcomes and the International Endocervical Adenocarcinoma Criteria and Classification.
Shi H, Shao Y, Lu W, Lu B
J Pathol Clin Res 2021 Jan;7(1):86-95. Epub 2020 Oct 22 doi: 10.1002/cjp2.184. PMID: 33089969Free PMC Article
A multi-center retrospective study of neuroendocrine tumors of the uterine cervix: Prognosis according to the new 2018 staging system, comparing outcomes for different chemotherapeutic regimens and histopathological subtypes.
Ishikawa M, Kasamatsu T, Tsuda H, Fukunaga M, Sakamoto A, Kaku T, Kato T, Takahashi K, Ariyoshi K, Suzuki K, Arimoto T, Matsumoto Y, Nakai H, Inoue T, Yokoyama M, Kawabata T, Kodama S, Miyamoto T, Takano M, Yaegashi N
Gynecol Oncol 2019 Dec;155(3):444-451. Epub 2019 Oct 18 doi: 10.1016/j.ygyno.2019.09.018. PMID: 31635755
Prognostic model based on magnetic resonance imaging, whole-tumour apparent diffusion coefficient values and HPV genotyping for stage IB-IV cervical cancer patients following chemoradiotherapy.
Lin G, Yang LY, Lin YC, Huang YT, Liu FY, Wang CC, Lu HY, Chiang HJ, Chen YR, Wu RC, Ng KK, Hong JH, Yen TC, Lai CH
Eur Radiol 2019 Feb;29(2):556-565. Epub 2018 Jul 26 doi: 10.1007/s00330-018-5651-4. PMID: 30051142

Prognosis

Systematic assessment of tumor necrosis at baseline in cervical cancer - An independent factor associated with poor outcome.
Chouchane-Mlik O, Oniga A, Latouche A, Halladjian M, Kleine-Borgmann FB, Gérardy JJ, Mittelbronn M, Kamal M, Scholl SM
Hum Pathol 2024 Jan;143:62-70. Epub 2023 Dec 20 doi: 10.1016/j.humpath.2023.12.003. PMID: 38135059
MRI-based radiomic signatures for pretreatment prognostication in cervical cancer.
Wagner-Larsen KS, Hodneland E, Fasmer KE, Lura N, Woie K, Bertelsen BI, Salvesen Ø, Halle MK, Smit N, Krakstad C, Haldorsen IS
Cancer Med 2023 Oct;12(20):20251-20265. Epub 2023 Oct 16 doi: 10.1002/cam4.6526. PMID: 37840437Free PMC Article
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
FIGO 2018 staging criteria for cervical cancer: Impact on stage migration and survival.
Grigsby PW, Massad LS, Mutch DG, Powell MA, Thaker PH, McCourt C, Hagemann A, Fuh K, Kuroki L, Schwarz JK, Markovina S, Lin AJ, Dehdashti F, Siegel BA
Gynecol Oncol 2020 Jun;157(3):639-643. Epub 2020 Apr 2 doi: 10.1016/j.ygyno.2020.03.027. PMID: 32248993
Human papillomavirus genotype and prognosis of cervical cancer: Favorable survival of patients with HPV16-positive tumors.
Onuki M, Matsumoto K, Tenjimbayashi Y, Tasaka N, Akiyama A, Sakurai M, Minaguchi T, Oki A, Satoh T, Yoshikawa H
Papillomavirus Res 2018 Dec;6:41-45. Epub 2018 Oct 19 doi: 10.1016/j.pvr.2018.10.005. PMID: 30347290Free PMC Article

Clinical prediction guides

MRI-based radiomic signatures for pretreatment prognostication in cervical cancer.
Wagner-Larsen KS, Hodneland E, Fasmer KE, Lura N, Woie K, Bertelsen BI, Salvesen Ø, Halle MK, Smit N, Krakstad C, Haldorsen IS
Cancer Med 2023 Oct;12(20):20251-20265. Epub 2023 Oct 16 doi: 10.1002/cam4.6526. PMID: 37840437Free PMC Article
Impact of HIV infection on access to cancer care and survival among women with invasive cervical cancer in Côte d'Ivoire: A prospective cohort study.
Boni SP, Horo A, Didi-Kouko-Coulibaly J, Tanon A, Tchounga BK, Coffie PA, Comoe JC, Moh RD, Dabis F, Adoubi I, Jaquet A; IeDEA West Africa Collaboration
Int J Gynaecol Obstet 2023 Nov;163(2):392-401. Epub 2023 Jun 22 doi: 10.1002/ijgo.14925. PMID: 37350012Free PMC Article
Serum Human Epididymis Protein 4 as a Prognostic Marker in Cervical Cancer.
Hwang WY, Suh DH, Kim K, Kim YB, No JH
Cancer Control 2022 Jan-Dec;29:10732748221097778. doi: 10.1177/10732748221097778. PMID: 35506739Free PMC Article
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Combination of weekly paclitaxel-carboplatin plus standard bevacizumab as neoadjuvant treatment in stage IB-IIB cervical cancer.
Maene C, Salihi RR, Van Nieuwenhuysen E, Han SN, Concin N, Vergote I
Int J Gynecol Cancer 2021 Jun;31(6):824-828. Epub 2021 Apr 15 doi: 10.1136/ijgc-2021-002432. PMID: 33858952

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