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Metastatic Proximal Gastric Adenocarcinoma

MedGen UID:
1711891
•Concept ID:
C5237324
•
Neoplastic Process

Definition

A proximal gastric adenocarcinoma that has spread from its original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Proximal Gastric Adenocarcinoma

Professional guidelines

PubMed

Comparative effectiveness of treatment modalities in non-metastatic gastric adenocarcinoma: a propensity score matching analysis of the National Cancer Database.
Barzi A, Yang D, Kim AW, Shah MA, Sadeghi S
BMJ Open Gastroenterol 2020 Nov;7(1) doi: 10.1136/bmjgast-2020-000483. PMID: 33148789Free PMC Article
Optimal management of gastroesophageal junction cancer.
Greally M, Agarwal R, Ilson DH
Cancer 2019 Jun 15;125(12):1990-2001. Epub 2019 Apr 11 doi: 10.1002/cncr.32066. PMID: 30973648Free PMC Article
Processes of care in the multidisciplinary treatment of gastric cancer: results of a RAND/UCLA expert panel.
Brar SS, Mahar AL, Helyer LK, Swallow C, Law C, Paszat L, Seevaratnam R, Cardoso R, McLeod R, Dixon M, Yohanathan L, Lourenco LG, Bocicariu A, Bekaii-Saab T, Chau I, Church N, Coit D, Crane CH, Earle C, Mansfield P, Marcon N, Miner T, Noh SH, Porter G, Posner MC, Prachand V, Sano T, van de Velde C, Wong S, Coburn NG
JAMA Surg 2014 Jan;149(1):18-25. doi: 10.1001/jamasurg.2013.3959. PMID: 24225775

Recent clinical studies

Etiology

Ranitidine Use and Gastric Cancer Among Persons with Helicobacter pylori.
Kumar S, Goldberg DS, Kaplan DE
Dig Dis Sci 2022 May;67(5):1822-1830. Epub 2021 Apr 15 doi: 10.1007/s10620-021-06972-w. PMID: 33856609
Oesophageal and proximal gastric adenocarcinomas are rare after detection of Helicobacter pylori infection.
Kumar S, Metz DC, Ginsberg GG, Kaplan DE, Goldberg DS
Aliment Pharmacol Ther 2020 Apr;51(8):781-788. Epub 2020 Mar 4 doi: 10.1111/apt.15677. PMID: 32133681Free PMC Article
Oncological safety of proximal gastrectomy for T2/T3 proximal gastric cancer.
Yura M, Yoshikawa T, Otsuki S, Yamagata Y, Morita S, Katai H, Nishida T, Yoshiaki T
Gastric Cancer 2019 Sep;22(5):1029-1035. Epub 2019 Feb 18 doi: 10.1007/s10120-019-00938-8. PMID: 30778799
Oncologic Effectiveness and Safety of Splenectomy in Total Gastrectomy for Proximal Gastric Carcinoma: Meta-analysis of Randomized Controlled Trials.
Marano L, Rondelli F, Bartoli A, Testini M, Castagnoli G, Ceccarelli G
Anticancer Res 2018 Jun;38(6):3609-3617. doi: 10.21873/anticanres.12635. PMID: 29848717
Gastric tumours in FAP.
Walton SJ, Frayling IM, Clark SK, Latchford A
Fam Cancer 2017 Jul;16(3):363-369. doi: 10.1007/s10689-017-9966-0. PMID: 28271232

Diagnosis

Oesophageal and proximal gastric adenocarcinomas are rare after detection of Helicobacter pylori infection.
Kumar S, Metz DC, Ginsberg GG, Kaplan DE, Goldberg DS
Aliment Pharmacol Ther 2020 Apr;51(8):781-788. Epub 2020 Mar 4 doi: 10.1111/apt.15677. PMID: 32133681Free PMC Article
Oncological safety of proximal gastrectomy for T2/T3 proximal gastric cancer.
Yura M, Yoshikawa T, Otsuki S, Yamagata Y, Morita S, Katai H, Nishida T, Yoshiaki T
Gastric Cancer 2019 Sep;22(5):1029-1035. Epub 2019 Feb 18 doi: 10.1007/s10120-019-00938-8. PMID: 30778799
Gastric tumours in FAP.
Walton SJ, Frayling IM, Clark SK, Latchford A
Fam Cancer 2017 Jul;16(3):363-369. doi: 10.1007/s10689-017-9966-0. PMID: 28271232
Zollinger-Ellison syndrome: classical considerations and current controversies.
Epelboym I, Mazeh H
Oncologist 2014 Jan;19(1):44-50. Epub 2013 Dec 6 doi: 10.1634/theoncologist.2013-0369. PMID: 24319020Free PMC Article
Carcinoid tumors.
Robertson RG, Geiger WJ, Davis NB
Am Fam Physician 2006 Aug 1;74(3):429-34. PMID: 16913162

Therapy

Optimal management of gastroesophageal junction cancer.
Greally M, Agarwal R, Ilson DH
Cancer 2019 Jun 15;125(12):1990-2001. Epub 2019 Apr 11 doi: 10.1002/cncr.32066. PMID: 30973648Free PMC Article
Oncologic Effectiveness and Safety of Splenectomy in Total Gastrectomy for Proximal Gastric Carcinoma: Meta-analysis of Randomized Controlled Trials.
Marano L, Rondelli F, Bartoli A, Testini M, Castagnoli G, Ceccarelli G
Anticancer Res 2018 Jun;38(6):3609-3617. doi: 10.21873/anticanres.12635. PMID: 29848717
Update on Gastroesophageal Adenocarcinoma Targeted Therapies.
Maron SB, Catenacci DVT
Hematol Oncol Clin North Am 2017 Jun;31(3):511-527. doi: 10.1016/j.hoc.2017.01.009. PMID: 28501091Free PMC Article
Perioperative therapy for locally advanced gastroesophageal cancer: current controversies and consensus of care.
Sehdev A, Catenacci DV
J Hematol Oncol 2013 Sep 5;6:66. doi: 10.1186/1756-8722-6-66. PMID: 24010946Free PMC Article
Gastric and gastro-oesophageal cancer therapy.
Das P, Ajani JA
Expert Opin Pharmacother 2005 Dec;6(16):2805-12. doi: 10.1517/14656566.6.16.2805. PMID: 16318431

Prognosis

Optimal management of gastroesophageal junction cancer.
Greally M, Agarwal R, Ilson DH
Cancer 2019 Jun 15;125(12):1990-2001. Epub 2019 Apr 11 doi: 10.1002/cncr.32066. PMID: 30973648Free PMC Article
Update on Gastroesophageal Adenocarcinoma Targeted Therapies.
Maron SB, Catenacci DVT
Hematol Oncol Clin North Am 2017 Jun;31(3):511-527. doi: 10.1016/j.hoc.2017.01.009. PMID: 28501091Free PMC Article
Novel Targeted Therapies for Esophagogastric Cancer.
Maron SB, Catenacci DV
Surg Oncol Clin N Am 2017 Apr;26(2):293-312. doi: 10.1016/j.soc.2016.10.002. PMID: 28279470Free PMC Article
Gastric tumours in FAP.
Walton SJ, Frayling IM, Clark SK, Latchford A
Fam Cancer 2017 Jul;16(3):363-369. doi: 10.1007/s10689-017-9966-0. PMID: 28271232
Carcinoid tumors.
Robertson RG, Geiger WJ, Davis NB
Am Fam Physician 2006 Aug 1;74(3):429-34. PMID: 16913162

Clinical prediction guides

Clinical significance of lower perigastric lymph nodes dissection in Siewert type II/III adenocarcinoma of esophagogastric junction: a retrospective propensity score matched study.
Li ZL, Zhao LY, Zhang WH, Liu K, Pang HY, Chen XL, Chen XZ, Yang K, Hu JK
Langenbecks Arch Surg 2022 May;407(3):985-998. Epub 2021 Nov 18 doi: 10.1007/s00423-021-02380-w. PMID: 34792614
Single-institute comparison of the efficacy of systemic chemotherapy for oesophagogastric junction adenocarcinoma and stomach adenocarscinoma in a metastatic setting.
Nakayama I, Takahari D, Wakatsuki T, Osumi H, Chin K, Ogura M, Sato T, Suzuki T, Kamiimabeppu D, Ooki A, Suenaga M, Shinozaki E, Yamaguchi K
ESMO Open 2020 Apr;5(2) doi: 10.1136/esmoopen-2019-000595. PMID: 32273288Free PMC Article
Gastric Cancer Peritoneal Carcinomatosis Risk Score.
Ji L, Selleck MJ, Morgan JW, Xu J, Babcock BD, Shavlik D, Wall NR, Langridge WH, Lum SS, Garberoglio CA, Reeves ME, Solomon N, Namm JP, Senthil M
Ann Surg Oncol 2020 Jan;27(1):240-247. Epub 2019 Jul 25 doi: 10.1245/s10434-019-07624-0. PMID: 31346896Free PMC Article
Gastric Adenocarcinoma in a Moroccan Population: First Report on Survival Data.
Lahmidani N, Miry S, Abid H, El Yousfi M, Benajah D, Ibrahimi A, El Abkari M, Najdi A
Gulf J Oncolog 2019 Sep;1(31):36-40. PMID: 31591989
Gastric tumours in FAP.
Walton SJ, Frayling IM, Clark SK, Latchford A
Fam Cancer 2017 Jul;16(3):363-369. doi: 10.1007/s10689-017-9966-0. PMID: 28271232

Recent systematic reviews

Nodal CTV selection according to primary tumour location and pT stage for biliary tract cancer.
Socha J, Surdyka D, Kepka L
J Med Imaging Radiat Oncol 2019 Dec;63(6):822-828. Epub 2019 Aug 11 doi: 10.1111/1754-9485.12937. PMID: 31402569
Oncologic Effectiveness and Safety of Splenectomy in Total Gastrectomy for Proximal Gastric Carcinoma: Meta-analysis of Randomized Controlled Trials.
Marano L, Rondelli F, Bartoli A, Testini M, Castagnoli G, Ceccarelli G
Anticancer Res 2018 Jun;38(6):3609-3617. doi: 10.21873/anticanres.12635. PMID: 29848717

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