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Metastatic Myxofibrosarcoma

MedGen UID:
1713126
•Concept ID:
C5239031
•
Neoplastic Process

Definition

Myxofibrosarcoma that has spread from its original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Myxofibrosarcoma

Professional guidelines

PubMed

Gemcitabine-Containing Chemotherapy for the Treatment of Metastatic Myxofibrosarcoma Refractory to Doxorubicin: A Case Series.
Elkrief A, Kazandjian S, Alcindor T
Curr Oncol 2021 Feb 5;28(1):813-817. doi: 10.3390/curroncol28010078. PMID: 33562486Free PMC Article

Recent clinical studies

Etiology

Pazopanib pharmacokinetically guided dose optimization in three cancer patients with gastrointestinal resection.
Tardy C, Puszkiel A, Boudou-Rouquette P, De Percin S, Alexandre J, Berge M, Ulmann G, Blanchet B, Batista R, Goldwasser F, Thomas Schoemann A
Cancer Chemother Pharmacol 2024 Feb;93(2):169-175. Epub 2023 Aug 24 doi: 10.1007/s00280-023-04574-z. PMID: 37620675
Gemcitabine-Containing Chemotherapy for the Treatment of Metastatic Myxofibrosarcoma Refractory to Doxorubicin: A Case Series.
Elkrief A, Kazandjian S, Alcindor T
Curr Oncol 2021 Feb 5;28(1):813-817. doi: 10.3390/curroncol28010078. PMID: 33562486Free PMC Article

Diagnosis

Mediastinal Myxofibrosarcoma Harboring Loss-of-Function MSH2 Variant in a Patient With Lynch Syndrome: A Case Report and Literature Review.
Jia L, Hwang H, De Las Casas L
Int J Surg Pathol 2023 Dec;31(8):1605-1609. Epub 2023 Apr 3 doi: 10.1177/10668969231166299. PMID: 37013349
Pazopanib-related secondary polycythemia in metastatic myxofibrosarcoma: A case report and review of the literature.
Fanelli M, Caputo F, Cerma K, Gelsomino F, Bari A, Dominici M, Pozzi S
J Oncol Pharm Pract 2021 Apr;27(3):766-770. Epub 2020 Aug 24 doi: 10.1177/1078155220950440. PMID: 32838682
Successful management of a rare type of complex myxofibrosarcoma which affected right lung and invading into the left atrium under the guidance of multimode image.
Zhang H, Zhu D, Dong L
Echocardiography 2018 Feb;35(2):285-286. doi: 10.1111/echo.13793. PMID: 29409129
Pembrolizumab for Refractory Metastatic Myxofibrosarcoma: A Case Report.
Song HN, Kang MG, Park JR, Hwang JY, Kang JH, Lee WS, Lee GW
Cancer Res Treat 2018 Oct;50(4):1458-1461. Epub 2018 Jan 22 doi: 10.4143/crt.2017.529. PMID: 29361819Free PMC Article
Occurrence of Multiple Tumors in a Patient.
Tan E, Friedman M, Coppola D
Cancer Control 2015 Oct;22(4):505-7. doi: 10.1177/107327481502200417. PMID: 26678978

Therapy

Pazopanib pharmacokinetically guided dose optimization in three cancer patients with gastrointestinal resection.
Tardy C, Puszkiel A, Boudou-Rouquette P, De Percin S, Alexandre J, Berge M, Ulmann G, Blanchet B, Batista R, Goldwasser F, Thomas Schoemann A
Cancer Chemother Pharmacol 2024 Feb;93(2):169-175. Epub 2023 Aug 24 doi: 10.1007/s00280-023-04574-z. PMID: 37620675
Metastatic Myxofibrosarcoma with Durable Response to Temozolomide Followed by Atezolizumab: A Case Report.
Lambden JP, Kelsten MF, Schulte BC, Abbinanti S, Hayes JP, Villaflor V, Agulnik M
Oncologist 2021 Jul;26(7):549-553. Epub 2021 Mar 8 doi: 10.1002/onco.13728. PMID: 33594725Free PMC Article
Gemcitabine-Containing Chemotherapy for the Treatment of Metastatic Myxofibrosarcoma Refractory to Doxorubicin: A Case Series.
Elkrief A, Kazandjian S, Alcindor T
Curr Oncol 2021 Feb 5;28(1):813-817. doi: 10.3390/curroncol28010078. PMID: 33562486Free PMC Article
Pazopanib-related secondary polycythemia in metastatic myxofibrosarcoma: A case report and review of the literature.
Fanelli M, Caputo F, Cerma K, Gelsomino F, Bari A, Dominici M, Pozzi S
J Oncol Pharm Pract 2021 Apr;27(3):766-770. Epub 2020 Aug 24 doi: 10.1177/1078155220950440. PMID: 32838682
Pembrolizumab for Refractory Metastatic Myxofibrosarcoma: A Case Report.
Song HN, Kang MG, Park JR, Hwang JY, Kang JH, Lee WS, Lee GW
Cancer Res Treat 2018 Oct;50(4):1458-1461. Epub 2018 Jan 22 doi: 10.4143/crt.2017.529. PMID: 29361819Free PMC Article

Clinical prediction guides

Pazopanib pharmacokinetically guided dose optimization in three cancer patients with gastrointestinal resection.
Tardy C, Puszkiel A, Boudou-Rouquette P, De Percin S, Alexandre J, Berge M, Ulmann G, Blanchet B, Batista R, Goldwasser F, Thomas Schoemann A
Cancer Chemother Pharmacol 2024 Feb;93(2):169-175. Epub 2023 Aug 24 doi: 10.1007/s00280-023-04574-z. PMID: 37620675
Gemcitabine-Containing Chemotherapy for the Treatment of Metastatic Myxofibrosarcoma Refractory to Doxorubicin: A Case Series.
Elkrief A, Kazandjian S, Alcindor T
Curr Oncol 2021 Feb 5;28(1):813-817. doi: 10.3390/curroncol28010078. PMID: 33562486Free PMC Article
Pazopanib-related secondary polycythemia in metastatic myxofibrosarcoma: A case report and review of the literature.
Fanelli M, Caputo F, Cerma K, Gelsomino F, Bari A, Dominici M, Pozzi S
J Oncol Pharm Pract 2021 Apr;27(3):766-770. Epub 2020 Aug 24 doi: 10.1177/1078155220950440. PMID: 32838682

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