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Locally Advanced Midgut Neuroendocrine Tumor

MedGen UID:
1714216
Concept ID:
C5238466
Neoplastic Process

Definition

A midgut neuroendocrine tumor that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Midgut Neuroendocrine Tumor

Professional guidelines

PubMed

Hallet J, Clarke CN
Ann Surg Oncol 2024 Mar;31(3):1704-1713. Epub 2024 Jan 2 doi: 10.1245/s10434-023-14802-8. PMID: 38167813
Alexandraki KI, Karapanagioti A, Karoumpalis I, Boutzios G, Kaltsas GA
Biomed Res Int 2017;2017:9856140. Epub 2017 Nov 19 doi: 10.1155/2017/9856140. PMID: 29349087Free PMC Article
Chung C
Am J Health Syst Pharm 2016 Nov 1;73(21):1729-1744. doi: 10.2146/ajhp150373. PMID: 27769969

Recent clinical studies

Etiology

Hallet J, Clarke CN
Ann Surg Oncol 2024 Mar;31(3):1704-1713. Epub 2024 Jan 2 doi: 10.1245/s10434-023-14802-8. PMID: 38167813
Strosberg JR, Caplin ME, Kunz PL, Ruszniewski PB, Bodei L, Hendifar A, Mittra E, Wolin EM, Yao JC, Pavel ME, Grande E, Van Cutsem E, Seregni E, Duarte H, Gericke G, Bartalotta A, Mariani MF, Demange A, Mutevelic S, Krenning EP; NETTER-1 investigators
Lancet Oncol 2021 Dec;22(12):1752-1763. Epub 2021 Nov 15 doi: 10.1016/S1470-2045(21)00572-6. PMID: 34793718
Alexandraki KI, Karapanagioti A, Karoumpalis I, Boutzios G, Kaltsas GA
Biomed Res Int 2017;2017:9856140. Epub 2017 Nov 19 doi: 10.1155/2017/9856140. PMID: 29349087Free PMC Article
Chan JA, Kulke MH
Curr Treat Options Oncol 2011 Jun;12(2):136-48. doi: 10.1007/s11864-011-0148-2. PMID: 21437592
Sutton R, Doran HE, Williams EM, Vora J, Vinjamuri S, Evans J, Campbell F, Raraty MG, Ghaneh P, Hartley M, Poston GJ, Neoptolemos JP
Endocr Relat Cancer 2003 Dec;10(4):469-81. doi: 10.1677/erc.0.0100469. PMID: 14713260

Diagnosis

Alexandraki KI, Karapanagioti A, Karoumpalis I, Boutzios G, Kaltsas GA
Biomed Res Int 2017;2017:9856140. Epub 2017 Nov 19 doi: 10.1155/2017/9856140. PMID: 29349087Free PMC Article
Chung C
Am J Health Syst Pharm 2016 Nov 1;73(21):1729-1744. doi: 10.2146/ajhp150373. PMID: 27769969
Saif MW
JOP 2011 Jul 8;12(4):316-21. PMID: 21737886
Boudreaux JP, Klimstra DS, Hassan MM, Woltering EA, Jensen RT, Goldsmith SJ, Nutting C, Bushnell DL, Caplin ME, Yao JC; North American Neuroendocrine Tumor Society (NANETS)
Pancreas 2010 Aug;39(6):753-66. doi: 10.1097/MPA.0b013e3181ebb2a5. PMID: 20664473
O'Toole D, Hentic O, Corcos O, Ruszniewski P
Neuroendocrinology 2004;80 Suppl 1:79-84. doi: 10.1159/000080747. PMID: 15477723

Therapy

Strosberg JR, Caplin ME, Kunz PL, Ruszniewski PB, Bodei L, Hendifar A, Mittra E, Wolin EM, Yao JC, Pavel ME, Grande E, Van Cutsem E, Seregni E, Duarte H, Gericke G, Bartalotta A, Mariani MF, Demange A, Mutevelic S, Krenning EP; NETTER-1 investigators
Lancet Oncol 2021 Dec;22(12):1752-1763. Epub 2021 Nov 15 doi: 10.1016/S1470-2045(21)00572-6. PMID: 34793718
Cives M, Pelle' E, Quaresmini D, Mandriani B, Tucci M, Silvestris F
Curr Treat Options Oncol 2019 Jul 25;20(9):72. doi: 10.1007/s11864-019-0669-7. PMID: 31346813
Alexandraki KI, Karapanagioti A, Karoumpalis I, Boutzios G, Kaltsas GA
Biomed Res Int 2017;2017:9856140. Epub 2017 Nov 19 doi: 10.1155/2017/9856140. PMID: 29349087Free PMC Article
Chung C
Am J Health Syst Pharm 2016 Nov 1;73(21):1729-1744. doi: 10.2146/ajhp150373. PMID: 27769969
Saif MW
JOP 2011 Jul 8;12(4):316-21. PMID: 21737886

Prognosis

Hallet J, Clarke CN
Ann Surg Oncol 2024 Mar;31(3):1704-1713. Epub 2024 Jan 2 doi: 10.1245/s10434-023-14802-8. PMID: 38167813
Strosberg JR, Caplin ME, Kunz PL, Ruszniewski PB, Bodei L, Hendifar A, Mittra E, Wolin EM, Yao JC, Pavel ME, Grande E, Van Cutsem E, Seregni E, Duarte H, Gericke G, Bartalotta A, Mariani MF, Demange A, Mutevelic S, Krenning EP; NETTER-1 investigators
Lancet Oncol 2021 Dec;22(12):1752-1763. Epub 2021 Nov 15 doi: 10.1016/S1470-2045(21)00572-6. PMID: 34793718
van Riet J, van de Werken HJG, Cuppen E, Eskens FALM, Tesselaar M, van Veenendaal LM, Klümpen HJ, Dercksen MW, Valk GD, Lolkema MP, Sleijfer S, Mostert B
Nat Commun 2021 Jul 29;12(1):4612. doi: 10.1038/s41467-021-24812-3. PMID: 34326338Free PMC Article
Saif MW
JOP 2011 Jul 8;12(4):316-21. PMID: 21737886
Sutton R, Doran HE, Williams EM, Vora J, Vinjamuri S, Evans J, Campbell F, Raraty MG, Ghaneh P, Hartley M, Poston GJ, Neoptolemos JP
Endocr Relat Cancer 2003 Dec;10(4):469-81. doi: 10.1677/erc.0.0100469. PMID: 14713260

Clinical prediction guides

Strosberg JR, Caplin ME, Kunz PL, Ruszniewski PB, Bodei L, Hendifar A, Mittra E, Wolin EM, Yao JC, Pavel ME, Grande E, Van Cutsem E, Seregni E, Duarte H, Gericke G, Bartalotta A, Mariani MF, Demange A, Mutevelic S, Krenning EP; NETTER-1 investigators
Lancet Oncol 2021 Dec;22(12):1752-1763. Epub 2021 Nov 15 doi: 10.1016/S1470-2045(21)00572-6. PMID: 34793718
Pavel M, Ćwikła JB, Lombard-Bohas C, Borbath I, Shah T, Pape UF, Capdevila J, Panzuto F, Truong Thanh XM, Houchard A, Ruszniewski P
Eur J Cancer 2021 Nov;157:403-414. Epub 2021 Sep 28 doi: 10.1016/j.ejca.2021.06.056. PMID: 34597974
van Riet J, van de Werken HJG, Cuppen E, Eskens FALM, Tesselaar M, van Veenendaal LM, Klümpen HJ, Dercksen MW, Valk GD, Lolkema MP, Sleijfer S, Mostert B
Nat Commun 2021 Jul 29;12(1):4612. doi: 10.1038/s41467-021-24812-3. PMID: 34326338Free PMC Article
Javle M, Hsueh CT
J Hematol Oncol 2010 Mar 23;3:11. doi: 10.1186/1756-8722-3-11. PMID: 20331897Free PMC Article

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