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Advanced Leiomyosarcoma

MedGen UID:
1714364
Concept ID:
C5237455
Neoplastic Process

Definition

A leiomyosarcoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Leiomyosarcoma

Professional guidelines

PubMed

D'Ambrosio L, Touati N, Blay JY, Grignani G, Flippot R, Czarnecka AM, Piperno-Neumann S, Martin-Broto J, Sanfilippo R, Katz D, Duffaud F, Vincenzi B, Stark DP, Mazzeo F, Tuchscherer A, Chevreau C, Sherriff J, Estival A, Litière S, Sents W, Ray-Coquard I, Tolomeo F, Le Cesne A, Rutkowski P, Stacchiotti S, Kasper B, Gelderblom H, Gronchi A; European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Cancer 2020 Jun 1;126(11):2637-2647. Epub 2020 Mar 4 doi: 10.1002/cncr.32795. PMID: 32129883
Akin S, Dizdar O, Karakas Y, Turker A, Kars A
Curr Probl Cancer 2018 May-Jun;42(3):344-349. Epub 2018 Jan 31 doi: 10.1016/j.currproblcancer.2018.01.011. PMID: 29576383

Recent clinical studies

Etiology

Madanat-Harjuoja LM, Klega K, Lu Y, Shulman DS, Thorner AR, Nag A, Tap WD, Reinke DK, Diller L, Ballman KV, George S, Crompton BD
Clin Cancer Res 2022 Jun 13;28(12):2579-2586. doi: 10.1158/1078-0432.CCR-21-3951. PMID: 35561344Free PMC Article
D'Ambrosio L, Touati N, Blay JY, Grignani G, Flippot R, Czarnecka AM, Piperno-Neumann S, Martin-Broto J, Sanfilippo R, Katz D, Duffaud F, Vincenzi B, Stark DP, Mazzeo F, Tuchscherer A, Chevreau C, Sherriff J, Estival A, Litière S, Sents W, Ray-Coquard I, Tolomeo F, Le Cesne A, Rutkowski P, Stacchiotti S, Kasper B, Gelderblom H, Gronchi A; European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Cancer 2020 Jun 1;126(11):2637-2647. Epub 2020 Mar 4 doi: 10.1002/cncr.32795. PMID: 32129883
Akin S, Dizdar O, Karakas Y, Turker A, Kars A
Curr Probl Cancer 2018 May-Jun;42(3):344-349. Epub 2018 Jan 31 doi: 10.1016/j.currproblcancer.2018.01.011. PMID: 29576383
Vincenzi B, Stacchiotti S, Collini P, Pantano F, Rabitti C, Perrone G, Iuliani M, Baldi A, Badalamenti G, Sanfilippo R, Santini D, Muda AO, Gronchi A, Casali P, Dei Tos AP, Tonini G
Br J Cancer 2017 Jul 25;117(3):340-346. Epub 2017 Jun 22 doi: 10.1038/bjc.2017.187. PMID: 28641307Free PMC Article
Seddon BM, Davda R
Eur J Radiol 2011 Apr;78(1):30-40. Epub 2011 Jan 17 doi: 10.1016/j.ejrad.2010.12.057. PMID: 21247711

Diagnosis

Vidri RJ, Howell KJ, Meyer JE, Rivard MJ, Emrich JG, Price RA, Farma JM, Turian JV, Poli J, Wang D
J Surg Res 2021 Dec;268:411-418. Epub 2021 Aug 17 doi: 10.1016/j.jss.2021.06.080. PMID: 34416413
D'Ambrosio L, Touati N, Blay JY, Grignani G, Flippot R, Czarnecka AM, Piperno-Neumann S, Martin-Broto J, Sanfilippo R, Katz D, Duffaud F, Vincenzi B, Stark DP, Mazzeo F, Tuchscherer A, Chevreau C, Sherriff J, Estival A, Litière S, Sents W, Ray-Coquard I, Tolomeo F, Le Cesne A, Rutkowski P, Stacchiotti S, Kasper B, Gelderblom H, Gronchi A; European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Cancer 2020 Jun 1;126(11):2637-2647. Epub 2020 Mar 4 doi: 10.1002/cncr.32795. PMID: 32129883
Akin S, Dizdar O, Karakas Y, Turker A, Kars A
Curr Probl Cancer 2018 May-Jun;42(3):344-349. Epub 2018 Jan 31 doi: 10.1016/j.currproblcancer.2018.01.011. PMID: 29576383
Galizia D, Palesandro E, Nuzzo AM, Pignochino Y, Aliberti S, Aglietta M, Grignani G
Oncol Res 2013;20(10):483-90. doi: 10.3727/096504013x13685487925130. PMID: 24308159
Seddon BM, Davda R
Eur J Radiol 2011 Apr;78(1):30-40. Epub 2011 Jan 17 doi: 10.1016/j.ejrad.2010.12.057. PMID: 21247711

Therapy

Turinetto M, Meeus P, Ray-Coquard I
Curr Opin Oncol 2023 Jul 1;35(4):288-291. Epub 2023 May 18 doi: 10.1097/CCO.0000000000000961. PMID: 37222199
Chen TW, Hsu CL, Hong RL, Lee JC, Chang K, Yu CW, Chen SC, Guo JC, Chen ML, Hsu MC, Kung TF, Cheng AL, Yen CC
Clin Cancer Res 2022 Dec 1;28(23):5058-5065. doi: 10.1158/1078-0432.CCR-22-2092. PMID: 36129471
Madanat-Harjuoja LM, Klega K, Lu Y, Shulman DS, Thorner AR, Nag A, Tap WD, Reinke DK, Diller L, Ballman KV, George S, Crompton BD
Clin Cancer Res 2022 Jun 13;28(12):2579-2586. doi: 10.1158/1078-0432.CCR-21-3951. PMID: 35561344Free PMC Article
Wagner MJ, Zhang Y, Cranmer LD, Loggers ET, Black G, McDonnell S, Maxwell S, Johnson R, Moore R, Hermida de Viveiros P, Aicher L, Smythe KS, He Q, Jones RL, Pollack SM
Clin Cancer Res 2022 Jun 1;28(11):2306-2312. doi: 10.1158/1078-0432.CCR-22-0240. PMID: 35349638Free PMC Article
D'Ambrosio L, Touati N, Blay JY, Grignani G, Flippot R, Czarnecka AM, Piperno-Neumann S, Martin-Broto J, Sanfilippo R, Katz D, Duffaud F, Vincenzi B, Stark DP, Mazzeo F, Tuchscherer A, Chevreau C, Sherriff J, Estival A, Litière S, Sents W, Ray-Coquard I, Tolomeo F, Le Cesne A, Rutkowski P, Stacchiotti S, Kasper B, Gelderblom H, Gronchi A; European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Cancer 2020 Jun 1;126(11):2637-2647. Epub 2020 Mar 4 doi: 10.1002/cncr.32795. PMID: 32129883

Prognosis

Akin S, Dizdar O, Karakas Y, Turker A, Kars A
Curr Probl Cancer 2018 May-Jun;42(3):344-349. Epub 2018 Jan 31 doi: 10.1016/j.currproblcancer.2018.01.011. PMID: 29576383
Vincenzi B, Stacchiotti S, Collini P, Pantano F, Rabitti C, Perrone G, Iuliani M, Baldi A, Badalamenti G, Sanfilippo R, Santini D, Muda AO, Gronchi A, Casali P, Dei Tos AP, Tonini G
Br J Cancer 2017 Jul 25;117(3):340-346. Epub 2017 Jun 22 doi: 10.1038/bjc.2017.187. PMID: 28641307Free PMC Article
Galizia D, Palesandro E, Nuzzo AM, Pignochino Y, Aliberti S, Aglietta M, Grignani G
Oncol Res 2013;20(10):483-90. doi: 10.3727/096504013x13685487925130. PMID: 24308159
Italiano A, Kind M, Stoeckle E, Jones N, Coindre JM, Bui B
Anticancer Drugs 2011 Jun;22(5):463-7. doi: 10.1097/CAD.0b013e3283442074. PMID: 21301319
Seddon BM, Davda R
Eur J Radiol 2011 Apr;78(1):30-40. Epub 2011 Jan 17 doi: 10.1016/j.ejrad.2010.12.057. PMID: 21247711

Clinical prediction guides

Wagner MJ, Zhang Y, Cranmer LD, Loggers ET, Black G, McDonnell S, Maxwell S, Johnson R, Moore R, Hermida de Viveiros P, Aicher L, Smythe KS, He Q, Jones RL, Pollack SM
Clin Cancer Res 2022 Jun 1;28(11):2306-2312. doi: 10.1158/1078-0432.CCR-22-0240. PMID: 35349638Free PMC Article
Vidri RJ, Howell KJ, Meyer JE, Rivard MJ, Emrich JG, Price RA, Farma JM, Turian JV, Poli J, Wang D
J Surg Res 2021 Dec;268:411-418. Epub 2021 Aug 17 doi: 10.1016/j.jss.2021.06.080. PMID: 34416413
D'Ambrosio L, Touati N, Blay JY, Grignani G, Flippot R, Czarnecka AM, Piperno-Neumann S, Martin-Broto J, Sanfilippo R, Katz D, Duffaud F, Vincenzi B, Stark DP, Mazzeo F, Tuchscherer A, Chevreau C, Sherriff J, Estival A, Litière S, Sents W, Ray-Coquard I, Tolomeo F, Le Cesne A, Rutkowski P, Stacchiotti S, Kasper B, Gelderblom H, Gronchi A; European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Cancer 2020 Jun 1;126(11):2637-2647. Epub 2020 Mar 4 doi: 10.1002/cncr.32795. PMID: 32129883
Vincenzi B, Stacchiotti S, Collini P, Pantano F, Rabitti C, Perrone G, Iuliani M, Baldi A, Badalamenti G, Sanfilippo R, Santini D, Muda AO, Gronchi A, Casali P, Dei Tos AP, Tonini G
Br J Cancer 2017 Jul 25;117(3):340-346. Epub 2017 Jun 22 doi: 10.1038/bjc.2017.187. PMID: 28641307Free PMC Article
Italiano A, Kind M, Stoeckle E, Jones N, Coindre JM, Bui B
Anticancer Drugs 2011 Jun;22(5):463-7. doi: 10.1097/CAD.0b013e3283442074. PMID: 21301319

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