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Advanced Fibrosarcoma

MedGen UID:
1715457
•Concept ID:
C5239070
•
Neoplastic Process

Definition

Fibrosarcoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Fibrosarcoma

Professional guidelines

PubMed

Surgical management of dermatofibrosarcoma protuberans.
Rust DJ, Kwinta BD, Geskin LJ, Samie FH, Remotti F, Yoon SS
J Surg Oncol 2023 Jul;128(1):87-96. Epub 2023 Mar 31 doi: 10.1002/jso.27258. PMID: 36999599
Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
Crago AM, Cardona K, Koseła-Paterczyk H, Rutkowski P
Surg Oncol Clin N Am 2022 Jul;31(3):419-430. doi: 10.1016/j.soc.2022.03.006. PMID: 35715142Free PMC Article
Differential Diagnosis of Benign Spindle Cell Lesions.
Magro G
Surg Pathol Clin 2018 Mar;11(1):91-121. Epub 2017 Dec 9 doi: 10.1016/j.path.2017.09.005. PMID: 29413661

Recent clinical studies

Etiology

An update on selected cutaneous (myo) fibroblastic mesenchymal tumors.
Georgantzoglou N, Linos K
Semin Diagn Pathol 2023 Jul;40(4):295-305. Epub 2023 Apr 25 doi: 10.1053/j.semdp.2023.04.018. PMID: 37150655Free PMC Article
Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
Crago AM, Cardona K, Koseła-Paterczyk H, Rutkowski P
Surg Oncol Clin N Am 2022 Jul;31(3):419-430. doi: 10.1016/j.soc.2022.03.006. PMID: 35715142Free PMC Article
Advances in the Diagnosis and Management of Neonatal Sarcomas.
Rashid T, Noyd DH, Iranzad N, Davis JT, Deel MD
Clin Perinatol 2021 Mar;48(1):117-145. doi: 10.1016/j.clp.2020.11.007. PMID: 33583500
Dermatofibrosarcoma Protuberans.
Reha J, Katz SC
Surg Clin North Am 2016 Oct;96(5):1031-46. doi: 10.1016/j.suc.2016.05.006. PMID: 27542641
Emerging therapies for adult soft tissue sarcoma.
Radaelli S, Stacchiotti S, Casali PG, Gronchi A
Expert Rev Anticancer Ther 2014 Jun;14(6):689-704. Epub 2014 Feb 20 doi: 10.1586/14737140.2014.885840. PMID: 24555529

Diagnosis

An update on selected cutaneous (myo) fibroblastic mesenchymal tumors.
Georgantzoglou N, Linos K
Semin Diagn Pathol 2023 Jul;40(4):295-305. Epub 2023 Apr 25 doi: 10.1053/j.semdp.2023.04.018. PMID: 37150655Free PMC Article
Dermatofibrosarcoma Protuberans: What Is This?
Vitiello GA, Lee AY, Berman RS
Surg Clin North Am 2022 Aug;102(4):657-665. doi: 10.1016/j.suc.2022.05.004. PMID: 35952694
Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
Crago AM, Cardona K, Koseła-Paterczyk H, Rutkowski P
Surg Oncol Clin N Am 2022 Jul;31(3):419-430. doi: 10.1016/j.soc.2022.03.006. PMID: 35715142Free PMC Article
Recent advances in the diagnosis, classification and molecular pathogenesis of cutaneous mesenchymal neoplasms.
Papke DJ Jr, Hornick JL
Histopathology 2022 Jan;80(1):216-232. doi: 10.1111/his.14450. PMID: 34958499
Advances in the Diagnosis and Management of Neonatal Sarcomas.
Rashid T, Noyd DH, Iranzad N, Davis JT, Deel MD
Clin Perinatol 2021 Mar;48(1):117-145. doi: 10.1016/j.clp.2020.11.007. PMID: 33583500

Therapy

Leptomeningeal metastases of solid cancer.
Le Rhun E, Galanis E
Curr Opin Neurol 2016 Dec;29(6):797-805. doi: 10.1097/WCO.0000000000000393. PMID: 27661208
Emerging therapies for adult soft tissue sarcoma.
Radaelli S, Stacchiotti S, Casali PG, Gronchi A
Expert Rev Anticancer Ther 2014 Jun;14(6):689-704. Epub 2014 Feb 20 doi: 10.1586/14737140.2014.885840. PMID: 24555529
The evolution of systemic therapy in sarcoma.
Constantinidou A, Pollack S, Loggers E, Rodler E, Jones RL
Expert Rev Anticancer Ther 2013 Feb;13(2):211-23. doi: 10.1586/era.12.161. PMID: 23406562
Fibrous and fibrohistiocytic neoplasms: an update.
Clarke LE
Dermatol Clin 2012 Oct;30(4):643-56, vi. Epub 2012 Aug 11 doi: 10.1016/j.det.2012.06.005. PMID: 23021051
Current treatment options in dermatofibrosarcoma protuberans.
Lemm D, Mügge LO, Mentzel T, Höffken K
J Cancer Res Clin Oncol 2009 May;135(5):653-65. Epub 2009 Feb 10 doi: 10.1007/s00432-009-0550-3. PMID: 19205737

Prognosis

Shaping Our Understanding of Malignant Peripheral Nerve Sheath Tumor: A Bibliometric Analysis of the 100 Most-Cited Articles.
Rechberger JS, Millesi E, Power EA, Wang H, Mardini S, Spinner RJ, Daniels DJ
World Neurosurg 2024 Apr;184:293-302.e11. Epub 2024 Jan 14 doi: 10.1016/j.wneu.2024.01.054. PMID: 38219800
Cancer-associated fibroblast-derived secreted phosphoprotein 1 contributes to resistance of hepatocellular carcinoma to sorafenib and lenvatinib.
Eun JW, Yoon JH, Ahn HR, Kim S, Kim YB, Lim SB, Park W, Kang TW, Baek GO, Yoon MG, Son JA, Weon JH, Kim SS, Cho HJ, Cheong JY
Cancer Commun (Lond) 2023 Apr;43(4):455-479. Epub 2023 Mar 14 doi: 10.1002/cac2.12414. PMID: 36919193Free PMC Article
"Hey! Whatever happened to hemangiopericytoma and fibrosarcoma?" An update on selected conceptual advances in soft tissue pathology which have occurred over the past 50 years.
Folpe AL
Hum Pathol 2020 Jan;95:113-136. Epub 2019 Oct 24 doi: 10.1016/j.humpath.2019.10.001. PMID: 31669060
Fibrous and fibrohistiocytic neoplasms: an update.
Clarke LE
Dermatol Clin 2012 Oct;30(4):643-56, vi. Epub 2012 Aug 11 doi: 10.1016/j.det.2012.06.005. PMID: 23021051
Advances in management of dermatofibrosarcoma protuberans.
Johnson-Jahangir H, Ratner D
Dermatol Clin 2011 Apr;29(2):191-200, viii. doi: 10.1016/j.det.2011.02.003. PMID: 21421145

Clinical prediction guides

Cancer-associated fibroblast-derived secreted phosphoprotein 1 contributes to resistance of hepatocellular carcinoma to sorafenib and lenvatinib.
Eun JW, Yoon JH, Ahn HR, Kim S, Kim YB, Lim SB, Park W, Kang TW, Baek GO, Yoon MG, Son JA, Weon JH, Kim SS, Cho HJ, Cheong JY
Cancer Commun (Lond) 2023 Apr;43(4):455-479. Epub 2023 Mar 14 doi: 10.1002/cac2.12414. PMID: 36919193Free PMC Article
Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
Crago AM, Cardona K, Koseła-Paterczyk H, Rutkowski P
Surg Oncol Clin N Am 2022 Jul;31(3):419-430. doi: 10.1016/j.soc.2022.03.006. PMID: 35715142Free PMC Article
"Hey! Whatever happened to hemangiopericytoma and fibrosarcoma?" An update on selected conceptual advances in soft tissue pathology which have occurred over the past 50 years.
Folpe AL
Hum Pathol 2020 Jan;95:113-136. Epub 2019 Oct 24 doi: 10.1016/j.humpath.2019.10.001. PMID: 31669060
A systems biology approach to overcome TRAIL resistance in cancer treatment.
Selvarajoo K
Prog Biophys Mol Biol 2017 Sep;128:142-154. Epub 2017 Mar 9 doi: 10.1016/j.pbiomolbio.2017.02.009. PMID: 28286052
Appropriate therapy for type 2 diabetes mellitus in view of pancreatic β-cell glucose toxicity: "the earlier, the better".
Kaneto H, Matsuoka TA, Kimura T, Obata A, Shimoda M, Kamei S, Mune T, Kaku K
J Diabetes 2016 Mar;8(2):183-9. Epub 2015 Oct 27 doi: 10.1111/1753-0407.12331. PMID: 26223490

Recent systematic reviews

Disease-Specific Mortality of Dermatofibrosarcoma Protuberans After Mohs Surgery Versus Wide Local Excision: A Systematic Review and Meta-Analysis.
Crum OM, O'Hern K, Demer AM, Brewer JD
Dermatol Surg 2024 Apr 1;50(4):317-321. Epub 2024 Feb 8 doi: 10.1097/DSS.0000000000004088. PMID: 38335454
Dermatofibrosarcoma protuberans of the scalp: Surgical management in a multicentric series of 11 cases and systematic review of the literature.
Kuhlmann C, Ehrl D, Taha S, Wachtel N, Schmid A, Bronsert P, Zeller J, Giunta RE, Eisenhardt SU, Braig D
Surgery 2023 Jun;173(6):1463-1475. Epub 2023 Apr 1 doi: 10.1016/j.surg.2023.02.026. PMID: 37012145
Transforming approaches to treating TRK fusion cancer: historical comparison of larotrectinib and histology-specific therapies.
Pollack M, Keating K, Wissinger E, Jackson L, Sarnes E, Cuffel B
Curr Med Res Opin 2021 Jan;37(1):59-70. Epub 2020 Nov 28 doi: 10.1080/03007995.2020.1847057. PMID: 33148054
A systematic review of targeted agents for non-small cell lung cancer.
Vestergaard HH, Christensen MR, Lassen UN
Acta Oncol 2018 Feb;57(2):176-186. Epub 2017 Nov 25 doi: 10.1080/0284186X.2017.1404634. PMID: 29172833
A systematic review and meta-analysis of randomized trials on the role of targeted therapy in the management of advanced gastric cancer: Evidence does not translate?
Ciliberto D, Staropoli N, Caglioti F, Gualtieri S, Fiorillo L, Chiellino S, De Angelis AM, Mendicino F, Botta C, Caraglia M, Tassone P, Tagliaferri P
Cancer Biol Ther 2015;16(8):1148-59. Epub 2015 Jun 10 doi: 10.1080/15384047.2015.1056415. PMID: 26061272Free PMC Article

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