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Abnormal cellular composition of bronchoalveolar fluid

MedGen UID:
1718141
Concept ID:
C5397966
Finding
Synonym: Abnormal cell differential of broncho-alveolar fluid
 
HPO: HP:0032974

Definition

Deviation from the commonly in healthy people observe cellular distribution. Normal ranges are macrophages over 80%, lymphocytes less than 15%, neutrophils less than 3%, eosinophils less than 0.5%, mast cells less than 0.5%. [from HPO]

Recent clinical studies

Etiology

Sulaiman I, Wu BG, Li Y, Scott AS, Malecha P, Scaglione B, Wang J, Basavaraj A, Chung S, Bantis K, Carpenito J, Clemente JC, Shen N, Bessich J, Rafeq S, Michaud G, Donington J, Naidoo C, Theron G, Schattner G, Garofano S, Condos R, Kamelhar D, Addrizzo-Harris D, Segal LN
Eur Respir J 2018 Oct;52(4) Epub 2018 Oct 25 doi: 10.1183/13993003.00810-2018. PMID: 30093571
Mander A, Langton-Hewer S, Bernhard W, Warner JO, Postle AD
Am J Respir Cell Mol Biol 2002 Dec;27(6):714-21. doi: 10.1165/rcmb.4746. PMID: 12444031
Rose RM, Catalano PJ, Koziel H, Furlong ST
Am J Respir Crit Care Med 1994 Feb;149(2 Pt 1):332-8. doi: 10.1164/ajrccm.149.2.8306026. PMID: 8306026
Ohar JA, Jackson F, Dettenmeier PA, Bedrossian CW, Tricomi SM, Evans RG
Chest 1992 Oct;102(4):999-1004. doi: 10.1378/chest.102.4.999. PMID: 1395816
Cormier Y, Bélanger J, Tardif A, Leblanc P, Laviolette M
Thorax 1986 Jan;41(1):28-33. doi: 10.1136/thx.41.1.28. PMID: 3704964Free PMC Article

Diagnosis

Sulaiman I, Wu BG, Li Y, Scott AS, Malecha P, Scaglione B, Wang J, Basavaraj A, Chung S, Bantis K, Carpenito J, Clemente JC, Shen N, Bessich J, Rafeq S, Michaud G, Donington J, Naidoo C, Theron G, Schattner G, Garofano S, Condos R, Kamelhar D, Addrizzo-Harris D, Segal LN
Eur Respir J 2018 Oct;52(4) Epub 2018 Oct 25 doi: 10.1183/13993003.00810-2018. PMID: 30093571
Noël-Georis I, Bernard A, Falmagne P, Wattiez R
Dis Markers 2001;17(4):271-84. doi: 10.1155/2001/607263. PMID: 11790894Free PMC Article
Fraire AE, Guntupalli KK, Greenberg SD, Cartwright J Jr, Chasen MH
South Med J 1993 Jan;86(1):67-77. PMID: 8420020
Ohar JA, Jackson F, Dettenmeier PA, Bedrossian CW, Tricomi SM, Evans RG
Chest 1992 Oct;102(4):999-1004. doi: 10.1378/chest.102.4.999. PMID: 1395816
Hamm H, Fabel H, Bartsch W
Clin Investig 1992 Aug;70(8):637-57. doi: 10.1007/BF00180279. PMID: 1392439Free PMC Article

Therapy

Fraire AE, Guntupalli KK, Greenberg SD, Cartwright J Jr, Chasen MH
South Med J 1993 Jan;86(1):67-77. PMID: 8420020
Ohar JA, Jackson F, Dettenmeier PA, Bedrossian CW, Tricomi SM, Evans RG
Chest 1992 Oct;102(4):999-1004. doi: 10.1378/chest.102.4.999. PMID: 1395816
Hamm H, Fabel H, Bartsch W
Clin Investig 1992 Aug;70(8):637-57. doi: 10.1007/BF00180279. PMID: 1392439Free PMC Article
Robinson PC, Watters LC, King TE, Mason RJ
Am Rev Respir Dis 1988 Mar;137(3):585-91. doi: 10.1164/ajrccm/137.3.585. PMID: 3345040
Watters LC, Schwarz MI, Cherniack RM, Waldron JA, Dunn TL, Stanford RE, King TE
Am Rev Respir Dis 1987 Mar;135(3):696-704. doi: 10.1164/arrd.1987.135.3.696. PMID: 3826895

Prognosis

Mander A, Langton-Hewer S, Bernhard W, Warner JO, Postle AD
Am J Respir Cell Mol Biol 2002 Dec;27(6):714-21. doi: 10.1165/rcmb.4746. PMID: 12444031
Fraire AE, Guntupalli KK, Greenberg SD, Cartwright J Jr, Chasen MH
South Med J 1993 Jan;86(1):67-77. PMID: 8420020
Ohar JA, Jackson F, Dettenmeier PA, Bedrossian CW, Tricomi SM, Evans RG
Chest 1992 Oct;102(4):999-1004. doi: 10.1378/chest.102.4.999. PMID: 1395816
Robinson PC, Watters LC, King TE, Mason RJ
Am Rev Respir Dis 1988 Mar;137(3):585-91. doi: 10.1164/ajrccm/137.3.585. PMID: 3345040
Bourbon JR, Farrell PM
Pediatr Res 1985 Mar;19(3):253-67. doi: 10.1203/00006450-198503000-00001. PMID: 3885150

Clinical prediction guides

Rose RM, Catalano PJ, Koziel H, Furlong ST
Am J Respir Crit Care Med 1994 Feb;149(2 Pt 1):332-8. doi: 10.1164/ajrccm.149.2.8306026. PMID: 8306026
Ohar JA, Jackson F, Dettenmeier PA, Bedrossian CW, Tricomi SM, Evans RG
Chest 1992 Oct;102(4):999-1004. doi: 10.1378/chest.102.4.999. PMID: 1395816
Watters LC, Schwarz MI, Cherniack RM, Waldron JA, Dunn TL, Stanford RE, King TE
Am Rev Respir Dis 1987 Mar;135(3):696-704. doi: 10.1164/arrd.1987.135.3.696. PMID: 3826895
Cormier Y, Bélanger J, Tardif A, Leblanc P, Laviolette M
Thorax 1986 Jan;41(1):28-33. doi: 10.1136/thx.41.1.28. PMID: 3704964Free PMC Article
Bourbon JR, Farrell PM
Pediatr Res 1985 Mar;19(3):253-67. doi: 10.1203/00006450-198503000-00001. PMID: 3885150

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