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Advanced Ovarian Serous Adenocarcinoma

MedGen UID:
1725741
•Concept ID:
C5418889
•
Neoplastic Process

Definition

Ovarian serous adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Ovarian Serous Adenocarcinoma

Professional guidelines

PubMed

Clear cell carcinoma of the ovary: Epidemiology, pathological and biological features, treatment options and clinical outcomes.
Gadducci A, Multinu F, Cosio S, Carinelli S, Ghioni M, Aletti GD
Gynecol Oncol 2021 Sep;162(3):741-750. Epub 2021 Jul 8 doi: 10.1016/j.ygyno.2021.06.033. PMID: 34247767
Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.
Armstrong DK, Alvarez RD, Bakkum-Gamez JN, Barroilhet L, Behbakht K, Berchuck A, Chen LM, Cristea M, DeRosa M, Eisenhauer EL, Gershenson DM, Gray HJ, Grisham R, Hakam A, Jain A, Karam A, Konecny GE, Leath CA, Liu J, Mahdi H, Martin L, Matei D, McHale M, McLean K, Miller DS, O'Malley DM, Percac-Lima S, Ratner E, Remmenga SW, Vargas R, Werner TL, Zsiros E, Burns JL, Engh AM
J Natl Compr Canc Netw 2021 Feb 2;19(2):191-226. doi: 10.6004/jnccn.2021.0007. PMID: 33545690
First-Line Management of Advanced High-Grade Serous Ovarian Cancer.
Mahmood RD, Morgan RD, Edmondson RJ, Clamp AR, Jayson GC
Curr Oncol Rep 2020 Jun 4;22(6):64. doi: 10.1007/s11912-020-00933-8. PMID: 32494876Free PMC Article

Recent clinical studies

Etiology

The expressions of bHLH gene HES1 and HES5 in advanced ovarian serous adenocarcinomas and their prognostic significance: a retrospective clinical study.
Wang X, Fu Y, Chen X, Ye J, Lü B, Ye F, Lü W, Xie X
J Cancer Res Clin Oncol 2010 Jul;136(7):989-96. Epub 2009 Dec 20 doi: 10.1007/s00432-009-0744-8. PMID: 20091184Free PMC Article

Diagnosis

Ovarian cancer cells with the CD117 phenotype are highly tumorigenic and are related to chemotherapy outcome.
Luo L, Zeng J, Liang B, Zhao Z, Sun L, Cao D, Yang J, Shen K
Exp Mol Pathol 2011 Oct;91(2):596-602. Epub 2011 Jul 20 doi: 10.1016/j.yexmp.2011.06.005. PMID: 21787767
The expressions of bHLH gene HES1 and HES5 in advanced ovarian serous adenocarcinomas and their prognostic significance: a retrospective clinical study.
Wang X, Fu Y, Chen X, Ye J, Lü B, Ye F, Lü W, Xie X
J Cancer Res Clin Oncol 2010 Jul;136(7):989-96. Epub 2009 Dec 20 doi: 10.1007/s00432-009-0744-8. PMID: 20091184Free PMC Article

Therapy

Ovarian cancer cells with the CD117 phenotype are highly tumorigenic and are related to chemotherapy outcome.
Luo L, Zeng J, Liang B, Zhao Z, Sun L, Cao D, Yang J, Shen K
Exp Mol Pathol 2011 Oct;91(2):596-602. Epub 2011 Jul 20 doi: 10.1016/j.yexmp.2011.06.005. PMID: 21787767
The expressions of bHLH gene HES1 and HES5 in advanced ovarian serous adenocarcinomas and their prognostic significance: a retrospective clinical study.
Wang X, Fu Y, Chen X, Ye J, Lü B, Ye F, Lü W, Xie X
J Cancer Res Clin Oncol 2010 Jul;136(7):989-96. Epub 2009 Dec 20 doi: 10.1007/s00432-009-0744-8. PMID: 20091184Free PMC Article

Prognosis

The expressions of bHLH gene HES1 and HES5 in advanced ovarian serous adenocarcinomas and their prognostic significance: a retrospective clinical study.
Wang X, Fu Y, Chen X, Ye J, Lü B, Ye F, Lü W, Xie X
J Cancer Res Clin Oncol 2010 Jul;136(7):989-96. Epub 2009 Dec 20 doi: 10.1007/s00432-009-0744-8. PMID: 20091184Free PMC Article
CA125 regression during neoadjuvant chemotherapy as an independent prognostic factor for survival in patients with advanced ovarian serous adenocarcinoma.
Tate S, Hirai Y, Takeshima N, Hasumi K
Gynecol Oncol 2005 Jan;96(1):143-9. doi: 10.1016/j.ygyno.2004.09.020. PMID: 15589593

Clinical prediction guides

CA125 regression during neoadjuvant chemotherapy as an independent prognostic factor for survival in patients with advanced ovarian serous adenocarcinoma.
Tate S, Hirai Y, Takeshima N, Hasumi K
Gynecol Oncol 2005 Jan;96(1):143-9. doi: 10.1016/j.ygyno.2004.09.020. PMID: 15589593

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    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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