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Metastatic Ocular Melanoma

MedGen UID:
1732756
•Concept ID:
C2242657
•
Neoplastic Process

Definition

Ocular melanoma that has spread from its original site of growth to another anatomic site. [from NCI]

Professional guidelines

PubMed

Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.
Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R
Surg Today 2013 Apr;43(4):367-71. Epub 2012 Jul 6 doi: 10.1007/s00595-012-0244-3. PMID: 22766897
Regional treatment options for patients with ocular melanoma metastatic to the liver.
Feldman ED, Pingpank JF, Alexander HR Jr
Ann Surg Oncol 2004 Mar;11(3):290-7. doi: 10.1245/aso.2004.07.004. PMID: 14993024
Treatment of uveal melanoma metastatic to the liver: a review of the M. D. Anderson Cancer Center experience and prognostic factors.
Bedikian AY, Legha SS, Mavligit G, Carrasco CH, Khorana S, Plager C, Papadopoulos N, Benjamin RS
Cancer 1995 Nov 1;76(9):1665-70. doi: 10.1002/1097-0142(19951101)76:9<1665::aid-cncr2820760925>3.0.co;2-j. PMID: 8635073

Recent clinical studies

Etiology

Metastatic melanoma to the liver: a contemporary and comprehensive review of surgical, systemic, and regional therapeutic options.
Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420
Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.
Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R
Surg Today 2013 Apr;43(4):367-71. Epub 2012 Jul 6 doi: 10.1007/s00595-012-0244-3. PMID: 22766897
Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families.
Njauw CN, Kim I, Piris A, Gabree M, Taylor M, Lane AM, DeAngelis MM, Gragoudas E, Duncan LM, Tsao H
PLoS One 2012;7(4):e35295. Epub 2012 Apr 24 doi: 10.1371/journal.pone.0035295. PMID: 22545102Free PMC Article
A pilot study of bevacizumab and interferon-α2b in ocular melanoma.
Guenterberg KD, Grignol VP, Relekar KV, Varker KA, Chen HX, Kendra KL, Olencki TE, Carson WE 3rd
Am J Clin Oncol 2011 Feb;34(1):87-91. doi: 10.1097/COC.0b013e3181d2ed67. PMID: 20458209Free PMC Article
Treatment of disseminated ocular melanoma with sequential fotemustine, interferon alpha, and interleukin 2.
Becker JC, Terheyden P, Kämpgen E, Wagner S, Neumann C, Schadendorf D, Steinmann A, Wittenberg G, Lieb W, Bröcker EB
Br J Cancer 2002 Oct 7;87(8):840-5. doi: 10.1038/sj.bjc.6600521. PMID: 12373596Free PMC Article

Diagnosis

Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.
Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R
Surg Today 2013 Apr;43(4):367-71. Epub 2012 Jul 6 doi: 10.1007/s00595-012-0244-3. PMID: 22766897
Metastatic ocular melanoma to the kidney 20 years after initial diagnosis.
Levin BM, Boulos FI, Herrell SD
Urology 2005 Sep;66(3):658. doi: 10.1016/j.urology.2005.03.035. PMID: 16140107
Indications for surgical resection of metastatic ocular melanoma. A case report and review of the literature.
Cunningham JD, Cirincione E, Ryan A, Canin-Endres J, Brower S
Int J Pancreatol 1998 Aug;24(1):49-53. doi: 10.1007/BF02787531. PMID: 9746890
Clinical study of [123I] N-(2-diethylaminoethyl)-4-iodobenzamide in the diagnosis of primary and metastatic ocular melanoma.
Bacin F, Michelot J, Bonafous J, Veyre A, Moreau MF, Kemeny JL, Chossat F, Bekhechi D
Acta Ophthalmol Scand 1998 Feb;76(1):56-61. doi: 10.1034/j.1600-0420.1998.760110.x. PMID: 9541435
The prevalence and location of metastases from ocular melanoma: imaging study in 110 patients.
Lorigan JG, Wallace S, Mavligit GM
AJR Am J Roentgenol 1991 Dec;157(6):1279-81. doi: 10.2214/ajr.157.6.1950883. PMID: 1950883

Therapy

Chemosaturation of the Liver - an Update.
Ebel S, Struck MF, van Boemmel F, Beeskow AB, Gößmann H, Denecke T
Rofo 2023 Jan;195(1):30-37. Epub 2022 Aug 17 doi: 10.1055/a-1858-3418. PMID: 35977553
Renal Allograft Failure After Ipilimumab Therapy for Metastatic Melanoma: A Case Report and Review of the Literature.
Jose A, Yiannoullou P, Bhutani S, Denley H, Morton M, Picton M, Summers A, van Dellen D, Augustine T
Transplant Proc 2016 Nov;48(9):3137-3141. doi: 10.1016/j.transproceed.2016.07.019. PMID: 27932166
Metastatic melanoma to the liver: a contemporary and comprehensive review of surgical, systemic, and regional therapeutic options.
Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420
Isolated hepatic perfusion for metastatic melanoma.
Yamamoto M, Zager JS
J Surg Oncol 2014 Mar;109(4):383-8. Epub 2013 Oct 25 doi: 10.1002/jso.23474. PMID: 24166748
A pilot study of bevacizumab and interferon-α2b in ocular melanoma.
Guenterberg KD, Grignol VP, Relekar KV, Varker KA, Chen HX, Kendra KL, Olencki TE, Carson WE 3rd
Am J Clin Oncol 2011 Feb;34(1):87-91. doi: 10.1097/COC.0b013e3181d2ed67. PMID: 20458209Free PMC Article

Prognosis

Isolated hepatic perfusion for metastatic melanoma.
Yamamoto M, Zager JS
J Surg Oncol 2014 Mar;109(4):383-8. Epub 2013 Oct 25 doi: 10.1002/jso.23474. PMID: 24166748
Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.
Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R
Surg Today 2013 Apr;43(4):367-71. Epub 2012 Jul 6 doi: 10.1007/s00595-012-0244-3. PMID: 22766897
A pilot study of bevacizumab and interferon-α2b in ocular melanoma.
Guenterberg KD, Grignol VP, Relekar KV, Varker KA, Chen HX, Kendra KL, Olencki TE, Carson WE 3rd
Am J Clin Oncol 2011 Feb;34(1):87-91. doi: 10.1097/COC.0b013e3181d2ed67. PMID: 20458209Free PMC Article
Metastatic ocular melanoma.
Abramson DH, Kerestzes R, Shamonki J
Arch Ophthalmol 2004 Apr;122(4):658-9. doi: 10.1001/archopht.122.4.658. PMID: 15078690
The prevalence and location of metastases from ocular melanoma: imaging study in 110 patients.
Lorigan JG, Wallace S, Mavligit GM
AJR Am J Roentgenol 1991 Dec;157(6):1279-81. doi: 10.2214/ajr.157.6.1950883. PMID: 1950883

Clinical prediction guides

Metastatic melanoma to the liver: a contemporary and comprehensive review of surgical, systemic, and regional therapeutic options.
Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420
A pilot study of bevacizumab and interferon-α2b in ocular melanoma.
Guenterberg KD, Grignol VP, Relekar KV, Varker KA, Chen HX, Kendra KL, Olencki TE, Carson WE 3rd
Am J Clin Oncol 2011 Feb;34(1):87-91. doi: 10.1097/COC.0b013e3181d2ed67. PMID: 20458209Free PMC Article
Clinical study of [123I] N-(2-diethylaminoethyl)-4-iodobenzamide in the diagnosis of primary and metastatic ocular melanoma.
Bacin F, Michelot J, Bonafous J, Veyre A, Moreau MF, Kemeny JL, Chossat F, Bekhechi D
Acta Ophthalmol Scand 1998 Feb;76(1):56-61. doi: 10.1034/j.1600-0420.1998.760110.x. PMID: 9541435
Treatment of uveal melanoma metastatic to the liver: a review of the M. D. Anderson Cancer Center experience and prognostic factors.
Bedikian AY, Legha SS, Mavligit G, Carrasco CH, Khorana S, Plager C, Papadopoulos N, Benjamin RS
Cancer 1995 Nov 1;76(9):1665-70. doi: 10.1002/1097-0142(19951101)76:9<1665::aid-cncr2820760925>3.0.co;2-j. PMID: 8635073
Survival in metastatic ocular melanoma.
Rajpal S, Moore R, Karakousis CP
Cancer 1983 Jul 15;52(2):334-6. doi: 10.1002/1097-0142(19830715)52:2<334::aid-cncr2820520225>3.0.co;2-e. PMID: 6190546

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