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Sinonasal Spindle Cell Squamous Cell Carcinoma

MedGen UID:
1734714
Concept ID:
C5420024
Neoplastic Process
Synonyms: Nasal Cavity and Paranasal Sinus Spindle Cell (Sarcomatoid) Squamous Cell Carcinoma; Nasal Cavity and Paranasal Sinus Spindle Cell Squamous Cell Carcinoma; Sinonasal Spindle Cell (Sarcomatoid) Squamous Cell Carcinoma

Definition

A poorly differentiated squamous cell carcinoma arising from the sinonasal tract. It is characterized by the presence of malignant cells with spindle cell features. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSinonasal Spindle Cell Squamous Cell Carcinoma

Professional guidelines

PubMed

Luk PP, Selinger CI, Cooper WA, Mahar A, Palme CE, O'Toole SA, Clark JR, Gupta R
Head Neck Pathol 2019 Sep;13(3):397-414. Epub 2018 Nov 22 doi: 10.1007/s12105-018-0988-1. PMID: 30467669Free PMC Article

Recent clinical studies

Etiology

Ackall FY, Issa K, Barak I, Teitelbaum J, Jang DW, Jung SH, Goldstein B, Carrau R, Abi Hachem R
Laryngoscope 2021 Apr;131(4):E1040-E1048. Epub 2020 Sep 22 doi: 10.1002/lary.29090. PMID: 32959912
Al-Qurayshi Z, Smith R, Walsh JE
Ann Otol Rhinol Laryngol 2020 Nov;129(11):1049-1055. Epub 2020 May 31 doi: 10.1177/0003489420929048. PMID: 32476435
Qazi ZU, Latif S, Awan SM
J Ayub Med Coll Abbottabad 2016 Oct-Dec;28(4):687-693. PMID: 28586604
Vazquez A, Khan MN, Blake DM, Patel TD, Baredes S, Eloy JA
Int Forum Allergy Rhinol 2015 Jan;5(1):85-91. Epub 2014 Oct 2 doi: 10.1002/alr.21418. PMID: 25278180
Bishop JA, Westra WH
Am J Surg Pathol 2012 Aug;36(8):1216-21. doi: 10.1097/PAS.0b013e318254ce54. PMID: 22534723Free PMC Article

Diagnosis

Al-Qurayshi Z, Smith R, Walsh JE
Ann Otol Rhinol Laryngol 2020 Nov;129(11):1049-1055. Epub 2020 May 31 doi: 10.1177/0003489420929048. PMID: 32476435
Luk PP, Selinger CI, Cooper WA, Mahar A, Palme CE, O'Toole SA, Clark JR, Gupta R
Head Neck Pathol 2019 Sep;13(3):397-414. Epub 2018 Nov 22 doi: 10.1007/s12105-018-0988-1. PMID: 30467669Free PMC Article
Qazi ZU, Latif S, Awan SM
J Ayub Med Coll Abbottabad 2016 Oct-Dec;28(4):687-693. PMID: 28586604
Vazquez A, Khan MN, Blake DM, Patel TD, Baredes S, Eloy JA
Int Forum Allergy Rhinol 2015 Jan;5(1):85-91. Epub 2014 Oct 2 doi: 10.1002/alr.21418. PMID: 25278180
Thompson LD
Eur Arch Otorhinolaryngol 1997;254(8):357-66. doi: 10.1007/BF01642550. PMID: 9332890

Therapy

Chang PC, Fischbein NJ, McCalmont TH, Kashani-Sabet M, Zettersten EM, Liu AY, Weissman JL
AJNR Am J Neuroradiol 2004 Jan;25(1):5-11. PMID: 14729519Free PMC Article
Thompson LD
Eur Arch Otorhinolaryngol 1997;254(8):357-66. doi: 10.1007/BF01642550. PMID: 9332890

Prognosis

Patel AM, Choudhry HS, Desai AD, Shah VP, Patel P, Eloy JA, Roden DF, Fang CH
Head Neck 2023 Mar;45(3):685-696. Epub 2022 Dec 30 doi: 10.1002/hed.27285. PMID: 36584171
Ackall FY, Issa K, Barak I, Teitelbaum J, Jang DW, Jung SH, Goldstein B, Carrau R, Abi Hachem R
Laryngoscope 2021 Apr;131(4):E1040-E1048. Epub 2020 Sep 22 doi: 10.1002/lary.29090. PMID: 32959912
Al-Qurayshi Z, Smith R, Walsh JE
Ann Otol Rhinol Laryngol 2020 Nov;129(11):1049-1055. Epub 2020 May 31 doi: 10.1177/0003489420929048. PMID: 32476435
Luk PP, Selinger CI, Cooper WA, Mahar A, Palme CE, O'Toole SA, Clark JR, Gupta R
Head Neck Pathol 2019 Sep;13(3):397-414. Epub 2018 Nov 22 doi: 10.1007/s12105-018-0988-1. PMID: 30467669Free PMC Article
Vazquez A, Khan MN, Blake DM, Patel TD, Baredes S, Eloy JA
Int Forum Allergy Rhinol 2015 Jan;5(1):85-91. Epub 2014 Oct 2 doi: 10.1002/alr.21418. PMID: 25278180

Clinical prediction guides

Ackall FY, Issa K, Barak I, Teitelbaum J, Jang DW, Jung SH, Goldstein B, Carrau R, Abi Hachem R
Laryngoscope 2021 Apr;131(4):E1040-E1048. Epub 2020 Sep 22 doi: 10.1002/lary.29090. PMID: 32959912
McHugh KE, Policarpio-Nicolas MLC
Acta Cytol 2019;63(5):431-437. Epub 2019 May 27 doi: 10.1159/000500351. PMID: 31132763
Bishop JA, Westra WH
Am J Surg Pathol 2012 Aug;36(8):1216-21. doi: 10.1097/PAS.0b013e318254ce54. PMID: 22534723Free PMC Article

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