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Refractory Uveal Melanoma

MedGen UID:
1771214
Concept ID:
C5420152
Neoplastic Process

Definition

Uveal melanoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Uveal Melanoma

Professional guidelines

PubMed

Switzer B, Piperno-Neumann S, Lyon J, Buchbinder E, Puzanov I
Am Soc Clin Oncol Educ Book 2023 Jan;43:e397478. doi: 10.1200/EDBK_397478. PMID: 37141553
Li Y, Wang Z, Guo T, Liu S, Feng C
J Int Med Res 2020 Mar;48(3):300060519886454. Epub 2019 Nov 28 doi: 10.1177/0300060519886454. PMID: 31777292Free PMC Article
Lane AM, Kim IK, Gragoudas ES
JAMA Ophthalmol 2018 Sep 1;136(9):981-986. doi: 10.1001/jamaophthalmol.2018.2466. PMID: 29955797Free PMC Article

Recent clinical studies

Etiology

Lim JZ, Crawford AZ, McGhee CNJ
Invest Ophthalmol Vis Sci 2023 Oct 3;64(13):44. doi: 10.1167/iovs.64.13.44. PMID: 37889509Free PMC Article
Hanout M, Kamil ZS, Alrjoub M, Laperriere N, Altomare F, Krema H
Eur J Ophthalmol 2022 Jan;32(1):NP1-NP4. Epub 2020 Jul 22 doi: 10.1177/1120672120944799. PMID: 32700563
Namikawa K, Takahashi A, Mori T, Tsutsumida A, Suzuki S, Motoi N, Jinnai S, Kage Y, Mizuta H, Muto Y, Nakano E, Yamazaki N
Melanoma Res 2020 Feb;30(1):76-84. doi: 10.1097/CMR.0000000000000617. PMID: 31095037
Heppt MV, Amaral T, Kähler KC, Heinzerling L, Hassel JC, Meissner M, Kreuzberg N, Loquai C, Reinhardt L, Utikal J, Dabrowski E, Gesierich A, Pföhler C, Terheyden P, Thoms KM, Zimmer L, Eigentler TK, Kirchberger MC, Stege HM, Meier F, Schlaak M, Berking C
J Immunother Cancer 2019 Nov 13;7(1):299. doi: 10.1186/s40425-019-0800-0. PMID: 31722735Free PMC Article
Lane AM, Kim IK, Gragoudas ES
JAMA Ophthalmol 2018 Sep 1;136(9):981-986. doi: 10.1001/jamaophthalmol.2018.2466. PMID: 29955797Free PMC Article

Diagnosis

Lim JZ, Crawford AZ, McGhee CNJ
Invest Ophthalmol Vis Sci 2023 Oct 3;64(13):44. doi: 10.1167/iovs.64.13.44. PMID: 37889509Free PMC Article
Switzer B, Piperno-Neumann S, Lyon J, Buchbinder E, Puzanov I
Am Soc Clin Oncol Educ Book 2023 Jan;43:e397478. doi: 10.1200/EDBK_397478. PMID: 37141553
Hanout M, Kamil ZS, Alrjoub M, Laperriere N, Altomare F, Krema H
Eur J Ophthalmol 2022 Jan;32(1):NP1-NP4. Epub 2020 Jul 22 doi: 10.1177/1120672120944799. PMID: 32700563
Lane AM, Kim IK, Gragoudas ES
JAMA Ophthalmol 2018 Sep 1;136(9):981-986. doi: 10.1001/jamaophthalmol.2018.2466. PMID: 29955797Free PMC Article
Furney SJ, Pedersen M, Gentien D, Dumont AG, Rapinat A, Desjardins L, Turajlic S, Piperno-Neumann S, de la Grange P, Roman-Roman S, Stern MH, Marais R
Cancer Discov 2013 Oct;3(10):1122-1129. Epub 2013 Jul 16 doi: 10.1158/2159-8290.CD-13-0330. PMID: 23861464Free PMC Article

Therapy

Carvajal RD, Butler MO, Shoushtari AN, Hassel JC, Ikeguchi A, Hernandez-Aya L, Nathan P, Hamid O, Piulats JM, Rioth M, Johnson DB, Luke JJ, Espinosa E, Leyvraz S, Collins L, Goodall HM, Ranade K, Holland C, Abdullah SE, Sacco JJ, Sato T
Nat Med 2022 Nov;28(11):2364-2373. Epub 2022 Oct 13 doi: 10.1038/s41591-022-02015-7. PMID: 36229663Free PMC Article
Li Y, Wang Z, Guo T, Liu S, Feng C
J Int Med Res 2020 Mar;48(3):300060519886454. Epub 2019 Nov 28 doi: 10.1177/0300060519886454. PMID: 31777292Free PMC Article
Heppt MV, Amaral T, Kähler KC, Heinzerling L, Hassel JC, Meissner M, Kreuzberg N, Loquai C, Reinhardt L, Utikal J, Dabrowski E, Gesierich A, Pföhler C, Terheyden P, Thoms KM, Zimmer L, Eigentler TK, Kirchberger MC, Stege HM, Meier F, Schlaak M, Berking C
J Immunother Cancer 2019 Nov 13;7(1):299. doi: 10.1186/s40425-019-0800-0. PMID: 31722735Free PMC Article
Lane AM, Kim IK, Gragoudas ES
JAMA Ophthalmol 2018 Sep 1;136(9):981-986. doi: 10.1001/jamaophthalmol.2018.2466. PMID: 29955797Free PMC Article
van der Ent W, Burrello C, Teunisse AF, Ksander BR, van der Velden PA, Jager MJ, Jochemsen AG, Snaar-Jagalska BE
Invest Ophthalmol Vis Sci 2014 Sep 23;55(10):6612-22. doi: 10.1167/iovs.14-15202. PMID: 25249605

Prognosis

Switzer B, Piperno-Neumann S, Lyon J, Buchbinder E, Puzanov I
Am Soc Clin Oncol Educ Book 2023 Jan;43:e397478. doi: 10.1200/EDBK_397478. PMID: 37141553
Li Y, Wang Z, Guo T, Liu S, Feng C
J Int Med Res 2020 Mar;48(3):300060519886454. Epub 2019 Nov 28 doi: 10.1177/0300060519886454. PMID: 31777292Free PMC Article
Heppt MV, Amaral T, Kähler KC, Heinzerling L, Hassel JC, Meissner M, Kreuzberg N, Loquai C, Reinhardt L, Utikal J, Dabrowski E, Gesierich A, Pföhler C, Terheyden P, Thoms KM, Zimmer L, Eigentler TK, Kirchberger MC, Stege HM, Meier F, Schlaak M, Berking C
J Immunother Cancer 2019 Nov 13;7(1):299. doi: 10.1186/s40425-019-0800-0. PMID: 31722735Free PMC Article
Lane AM, Kim IK, Gragoudas ES
JAMA Ophthalmol 2018 Sep 1;136(9):981-986. doi: 10.1001/jamaophthalmol.2018.2466. PMID: 29955797Free PMC Article
Furney SJ, Pedersen M, Gentien D, Dumont AG, Rapinat A, Desjardins L, Turajlic S, Piperno-Neumann S, de la Grange P, Roman-Roman S, Stern MH, Marais R
Cancer Discov 2013 Oct;3(10):1122-1129. Epub 2013 Jul 16 doi: 10.1158/2159-8290.CD-13-0330. PMID: 23861464Free PMC Article

Clinical prediction guides

Hanout M, Kamil ZS, Alrjoub M, Laperriere N, Altomare F, Krema H
Eur J Ophthalmol 2022 Jan;32(1):NP1-NP4. Epub 2020 Jul 22 doi: 10.1177/1120672120944799. PMID: 32700563
Figueiredo CR, Kalirai H, Sacco JJ, Azevedo RA, Duckworth A, Slupsky JR, Coulson JM, Coupland SE
J Pathol 2020 Apr;250(4):420-439. doi: 10.1002/path.5384. PMID: 31960425Free PMC Article
Li Y, Wang Z, Guo T, Liu S, Feng C
J Int Med Res 2020 Mar;48(3):300060519886454. Epub 2019 Nov 28 doi: 10.1177/0300060519886454. PMID: 31777292Free PMC Article
Lane AM, Kim IK, Gragoudas ES
JAMA Ophthalmol 2018 Sep 1;136(9):981-986. doi: 10.1001/jamaophthalmol.2018.2466. PMID: 29955797Free PMC Article
Furney SJ, Pedersen M, Gentien D, Dumont AG, Rapinat A, Desjardins L, Turajlic S, Piperno-Neumann S, de la Grange P, Roman-Roman S, Stern MH, Marais R
Cancer Discov 2013 Oct;3(10):1122-1129. Epub 2013 Jul 16 doi: 10.1158/2159-8290.CD-13-0330. PMID: 23861464Free PMC Article

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