U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal pulmonary alveolar system morphology

MedGen UID:
1773274
•Concept ID:
C5421634
•
Anatomical Abnormality
HPO: HP:0033137

Definition

A structural abnormality of the pulmonary acinus, alveolar parenchyma, or alveoli. [from HPO]

Recent clinical studies

Therapy

E-cigarette or vaping product use-associated lung injury: A review of clinico-radio-pathological characteristics.
Garg I, Vidholia A, Garg A, Singh S, Agahi A, Laroia A, Saboo SS, Comellas AP, Hoffman EA, Nagpal P
Respir Investig 2022 Nov;60(6):738-749. Epub 2022 Aug 11 doi: 10.1016/j.resinv.2022.06.011. PMID: 35963780
Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression.
Davis ES, Ghosh A, Coakley RD, Wrennall JA, Lubamba BA, Rowell TR, Dang H, Pawlak EA, Li Q, Alexis NE, Ribeiro CMP, Tarran R
Nicotine Tob Res 2022 Feb 14;24(3):395-399. doi: 10.1093/ntr/ntab186. PMID: 34519792Free PMC Article
Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia.
Sun F, Wang G, Pradhan A, Xu K, Gomez-Arroyo J, Zhang Y, Kalin GT, Deng Z, Vagnozzi RJ, He H, Dunn AW, Wang Y, York AJ, Hegde RS, Woods JC, Kalin TV, Molkentin JD, Kalinichenko VV
Circulation 2021 Aug 17;144(7):539-555. Epub 2021 Jun 11 doi: 10.1161/CIRCULATIONAHA.121.053980. PMID: 34111939Free PMC Article
Radiologic, Pathologic, Clinical, and Physiologic Findings of Electronic Cigarette or Vaping Product Use-associated Lung Injury (EVALI): Evolving Knowledge and Remaining Questions.
Kligerman S, Raptis C, Larsen B, Henry TS, Caporale A, Tazelaar H, Schiebler ML, Wehrli FW, Klein JS, Kanne J
Radiology 2020 Mar;294(3):491-505. Epub 2020 Jan 28 doi: 10.1148/radiol.2020192585. PMID: 31990264
Respiratory and immunologic consequences of marijuana smoking.
Tashkin DP, Baldwin GC, Sarafian T, Dubinett S, Roth MD
J Clin Pharmacol 2002 Nov;42(S1):71S-81S. doi: 10.1002/j.1552-4604.2002.tb06006.x. PMID: 12412839

Prognosis

The Epithelial-Immune Crosstalk in Pulmonary Fibrosis.
Planté-Bordeneuve T, Pilette C, Froidure A
Front Immunol 2021;12:631235. Epub 2021 May 19 doi: 10.3389/fimmu.2021.631235. PMID: 34093523Free PMC Article
Proteomics in idiopathic pulmonary fibrosis: the quest for biomarkers.
Khan T, Dasgupta S, Ghosh N, Chaudhury K
Mol Omics 2021 Feb 22;17(1):43-58. doi: 10.1039/d0mo00108b. PMID: 33073811
Cardiovascular and Pulmonary Manifestations of Systemic Lupus Erythematosus.
Tselios K, Urowitz MB
Curr Rheumatol Rev 2017;13(3):206-218. doi: 10.2174/1573397113666170704102444. PMID: 28675998
Idiopathic non-specific interstitial pneumonia.
Belloli EA, Beckford R, Hadley R, Flaherty KR
Respirology 2016 Feb;21(2):259-68. Epub 2015 Nov 13 doi: 10.1111/resp.12674. PMID: 26564810
Smoking-related interstitial pneumonias and pulmonary Langerhans cell histiocytosis.
Caminati A, Harari S
Proc Am Thorac Soc 2006 Jun;3(4):299-306. doi: 10.1513/pats.200512-135TK. PMID: 16738193

Clinical prediction guides

Lung involvement in children with lysinuric protein intolerance.
Valimahamed-Mitha S, Berteloot L, Ducoin H, Ottolenghi C, de Lonlay P, de Blic J
J Inherit Metab Dis 2015 Mar;38(2):257-63. Epub 2014 Oct 22 doi: 10.1007/s10545-014-9777-5. PMID: 25335805
Alveolar hypoxia, alveolar macrophages, and systemic inflammation.
Chao J, Wood JG, Gonzalez NC
Respir Res 2009 Jun 22;10(1):54. doi: 10.1186/1465-9921-10-54. PMID: 19545431Free PMC Article
Cytopathology or immunopathology? The puzzle of cytomegalovirus pneumonitis revisited.
Barry SM, Johnson MA, Janossy G
Bone Marrow Transplant 2000 Sep;26(6):591-7. doi: 10.1038/sj.bmt.1702562. PMID: 11035367Free PMC Article
Micronodular pneumocyte hyperplasia.
Muir TE, Leslie KO, Popper H, Kitaichi M, Gagné E, Emelin JK, Vinters HV, Colby TV
Am J Surg Pathol 1998 Apr;22(4):465-72. doi: 10.1097/00000478-199804000-00012. PMID: 9537475
Assessment of the severity of pulmonary emphysema by computed tomography.
Zompatori M, Fasano L, Fabbri M, Maraldi F, Carvelli P, Laporta T, Pacilli A
Monaldi Arch Chest Dis 1997 Apr;52(2):147-54. PMID: 9203813

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...