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Ovarian Mixed Cell Adenocarcinoma

MedGen UID:
1792063
Concept ID:
C5555622
Neoplastic Process
Synonym: Ovarian Mixed Carcinoma

Definition

An adenocarcinoma that arises from the ovary and is characterized by the presence of two or more adenocarcinoma components, most often endometrioid and clear cell. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Mixed Cell Adenocarcinoma

Professional guidelines

PubMed

Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Friedlander ML, Russell K, Millis S, Gatalica Z, Bender R, Voss A
Int J Gynecol Cancer 2016 May;26(4):648-54. doi: 10.1097/IGC.0000000000000677. PMID: 26937756Free PMC Article
Shappell HW, Riopel MA, Smith Sehdev AE, Ronnett BM, Kurman RJ
Am J Surg Pathol 2002 Dec;26(12):1529-41. doi: 10.1097/00000478-200212000-00001. PMID: 12459620

Recent clinical studies

Etiology

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
J Gynecol Oncol 2023 Sep;34(5):e85. Epub 2023 Aug 8 doi: 10.3802/jgo.2023.34.e85. PMID: 37593813Free PMC Article
Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
Int J Gynaecol Obstet 2023 Aug;162(2):383-394. Epub 2023 Jun 20 doi: 10.1002/ijgo.14923. PMID: 37337978
Zhou L, Yao L, Dai L, Zhu H, Ye X, Wang S, Cheng H, Ma R, Liu H, Cui H, Chang X
J Ovarian Res 2021 May 4;14(1):63. doi: 10.1186/s13048-021-00804-1. PMID: 33941230Free PMC Article
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421
Devouassoux-Shisheboran M, Genestie C
Chin J Cancer 2015 Jan;34(1):50-5. doi: 10.5732/cjc.014.10273. PMID: 25556618Free PMC Article

Diagnosis

Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Zhou L, Yao L, Dai L, Zhu H, Ye X, Wang S, Cheng H, Ma R, Liu H, Cui H, Chang X
J Ovarian Res 2021 May 4;14(1):63. doi: 10.1186/s13048-021-00804-1. PMID: 33941230Free PMC Article
Matias-Guiu X, Stewart CJR
Pathology 2018 Feb;50(2):190-204. Epub 2017 Dec 11 doi: 10.1016/j.pathol.2017.10.006. PMID: 29241974
Paner GP, Lopez-Beltran A, Sirohi D, Amin MB
Adv Anat Pathol 2016 Mar;23(2):71-83. doi: 10.1097/PAP.0000000000000110. PMID: 26849813
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421

Therapy

Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Best SL, Liu Y, Keikhosravi A, Drifka CR, Woo KM, Mehta GS, Altwegg M, Thimm TN, Houlihan M, Bredfeldt JS, Abel EJ, Huang W, Eliceiri KW
BMC Cancer 2019 May 23;19(1):490. doi: 10.1186/s12885-019-5708-z. PMID: 31122202Free PMC Article
Takenaka M, Köbel M, Garsed DW, Fereday S, Pandey A, Etemadmoghadam D, Hendley J, Kawabata A, Noguchi D, Yanaihara N, Takahashi H, Kiyokawa T, Ikegami M, Takano H, Isonishi S, Ochiai K, Traficante N, Gadipally S, Semple T, Vassiliadis D, Amarasinghe K, Li J, Mir Arnau G, Okamoto A, Friedlander M, Bowtell DDL; Australian Ovarian Cancer Study Group
Clin Cancer Res 2019 Jul 1;25(13):3962-3973. Epub 2019 Apr 9 doi: 10.1158/1078-0432.CCR-18-3691. PMID: 30967419
Karami S, Daughtery SE, Schwartz K, Davis FG, Ruterbusch JJ, Wacholder S, Graubard BI, Berndt SI, Hofmann JN, Purdue MP, Moore LE, Colt JS
Int J Cancer 2016 Aug 1;139(3):584-92. Epub 2016 Apr 9 doi: 10.1002/ijc.30108. PMID: 27009534Free PMC Article
McNutt MA, Bolen JW, Gown AM, Hammar SP, Vogel AM
Ultrastruct Pathol 1985;9(1-2):31-43. doi: 10.3109/01913128509055483. PMID: 2418559

Prognosis

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
J Gynecol Oncol 2023 Sep;34(5):e85. Epub 2023 Aug 8 doi: 10.3802/jgo.2023.34.e85. PMID: 37593813Free PMC Article
Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
Int J Gynaecol Obstet 2023 Aug;162(2):383-394. Epub 2023 Jun 20 doi: 10.1002/ijgo.14923. PMID: 37337978
Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Liu X, Zhang X, Pang Y, Ma Y, Zhang X, Liu P
Arch Gynecol Obstet 2020 Apr;301(4):901-912. Epub 2020 Mar 17 doi: 10.1007/s00404-020-05502-9. PMID: 32185550
Matias-Guiu X, Stewart CJR
Pathology 2018 Feb;50(2):190-204. Epub 2017 Dec 11 doi: 10.1016/j.pathol.2017.10.006. PMID: 29241974

Clinical prediction guides

Sensu S, Keser SH, Gurbuz Y, Barisik NO, Gul AE
Arch Iran Med 2021 Apr 1;24(4):301-305. doi: 10.34172/aim.2021.42. PMID: 34196190
Koopman T, van der Vegt B, Dijkstra M, Bart J, Duiker E, Wisman GBA, de Bock GH, Hollema H
Histopathology 2018 Nov;73(5):852-863. Epub 2018 Sep 19 doi: 10.1111/his.13704. PMID: 29989198
Matias-Guiu X, Stewart CJR
Pathology 2018 Feb;50(2):190-204. Epub 2017 Dec 11 doi: 10.1016/j.pathol.2017.10.006. PMID: 29241974
Paner GP, Lopez-Beltran A, Sirohi D, Amin MB
Adv Anat Pathol 2016 Mar;23(2):71-83. doi: 10.1097/PAP.0000000000000110. PMID: 26849813
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421

Recent systematic reviews

Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421

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