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Metastatic Microsatellite Stable Ovarian Carcinoma

MedGen UID:
1792732
•Concept ID:
C5556291
•
Neoplastic Process

Definition

Microsatellite stable ovarian carcinoma that has spread from its original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Microsatellite Stable Ovarian Carcinoma

Recent clinical studies

Etiology

Phase 1/2 study of monalizumab plus durvalumab in patients with advanced solid tumors.
Patel SP, Alonso-Gordoa T, Banerjee S, Wang D, Naidoo J, Standifer NE, Palmer DC, Cheng LY, Kourtesis P, Ascierto ML, Das M, Diamond JR, Hellmann MD, Carneiro BA
J Immunother Cancer 2024 Feb 2;12(2) doi: 10.1136/jitc-2023-007340. PMID: 38309722Free PMC Article
Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer.
Stasenko M, Tunnage I, Ashley CW, Rubinstein MM, Latham AJ, Da Cruz Paula A, Mueller JJ, Leitao MM Jr, Friedman CF, Makker V, Soslow RA, DeLair DF, Hyman DM, Zamarin D, Alektiar KM, Aghajanian CA, Abu-Rustum NR, Weigelt B, Cadoo KA
Gynecol Oncol 2020 Jan;156(1):194-202. Epub 2019 Nov 19 doi: 10.1016/j.ygyno.2019.10.028. PMID: 31757464Free PMC Article
Genomic aberrations in borderline ovarian tumors.
Micci F, Haugom L, Ahlquist T, Andersen HK, Abeler VM, Davidson B, Trope CG, Lothe RA, Heim S
J Transl Med 2010 Feb 26;8:21. doi: 10.1186/1479-5876-8-21. PMID: 20184781Free PMC Article

Diagnosis

Comparison of Mismatch Repair Status Between Primary and Matched Metastatic Sites in Patients With Colorectal Cancer.
He WZ, Hu WM, Wang F, Rong YM, Yang L, Xie QK, Yang YZ, Jiang C, Qiu HJ, Lu JB, Zhang B, Ding PR, Xia XJ, Shao JY, Xia LP
J Natl Compr Canc Netw 2019 Oct 1;17(10):1174-1183. doi: 10.6004/jnccn.2019.7308. PMID: 31590148

Therapy

Phase 1/2 study of monalizumab plus durvalumab in patients with advanced solid tumors.
Patel SP, Alonso-Gordoa T, Banerjee S, Wang D, Naidoo J, Standifer NE, Palmer DC, Cheng LY, Kourtesis P, Ascierto ML, Das M, Diamond JR, Hellmann MD, Carneiro BA
J Immunother Cancer 2024 Feb 2;12(2) doi: 10.1136/jitc-2023-007340. PMID: 38309722Free PMC Article
Phase IB study of ziv-aflibercept plus pembrolizumab in patients with advanced solid tumors.
Rahma OE, Tyan K, Giobbie-Hurder A, Brohl AS, Bedard PL, Renouf DJ, Sharon E, Streicher H, Hathaway E, Cunningham R, Manos M, Severgnini M, Rodig S, Stephen Hodi F
J Immunother Cancer 2022 Mar;10(3) doi: 10.1136/jitc-2021-003569. PMID: 35264434Free PMC Article
Optimizing immunotherapy for gynecologic cancers.
Rubinstein MM, Makker V
Curr Opin Obstet Gynecol 2020 Feb;32(1):1-8. doi: 10.1097/GCO.0000000000000603. PMID: 31833942Free PMC Article
A change in microsatellite instability caused by cisplatin-based chemotherapy of ovarian cancer.
Watanabe Y, Koi M, Hemmi H, Hoshai H, Noda K
Br J Cancer 2001 Sep 28;85(7):1064-9. doi: 10.1054/bjoc.2001.2037. PMID: 11592780Free PMC Article

Prognosis

Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer.
Stasenko M, Tunnage I, Ashley CW, Rubinstein MM, Latham AJ, Da Cruz Paula A, Mueller JJ, Leitao MM Jr, Friedman CF, Makker V, Soslow RA, DeLair DF, Hyman DM, Zamarin D, Alektiar KM, Aghajanian CA, Abu-Rustum NR, Weigelt B, Cadoo KA
Gynecol Oncol 2020 Jan;156(1):194-202. Epub 2019 Nov 19 doi: 10.1016/j.ygyno.2019.10.028. PMID: 31757464Free PMC Article
Comparison of Mismatch Repair Status Between Primary and Matched Metastatic Sites in Patients With Colorectal Cancer.
He WZ, Hu WM, Wang F, Rong YM, Yang L, Xie QK, Yang YZ, Jiang C, Qiu HJ, Lu JB, Zhang B, Ding PR, Xia XJ, Shao JY, Xia LP
J Natl Compr Canc Netw 2019 Oct 1;17(10):1174-1183. doi: 10.6004/jnccn.2019.7308. PMID: 31590148
A change in microsatellite instability caused by cisplatin-based chemotherapy of ovarian cancer.
Watanabe Y, Koi M, Hemmi H, Hoshai H, Noda K
Br J Cancer 2001 Sep 28;85(7):1064-9. doi: 10.1054/bjoc.2001.2037. PMID: 11592780Free PMC Article

Clinical prediction guides

Phase 1/2 study of monalizumab plus durvalumab in patients with advanced solid tumors.
Patel SP, Alonso-Gordoa T, Banerjee S, Wang D, Naidoo J, Standifer NE, Palmer DC, Cheng LY, Kourtesis P, Ascierto ML, Das M, Diamond JR, Hellmann MD, Carneiro BA
J Immunother Cancer 2024 Feb 2;12(2) doi: 10.1136/jitc-2023-007340. PMID: 38309722Free PMC Article
Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer.
Stasenko M, Tunnage I, Ashley CW, Rubinstein MM, Latham AJ, Da Cruz Paula A, Mueller JJ, Leitao MM Jr, Friedman CF, Makker V, Soslow RA, DeLair DF, Hyman DM, Zamarin D, Alektiar KM, Aghajanian CA, Abu-Rustum NR, Weigelt B, Cadoo KA
Gynecol Oncol 2020 Jan;156(1):194-202. Epub 2019 Nov 19 doi: 10.1016/j.ygyno.2019.10.028. PMID: 31757464Free PMC Article

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