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Metastatic Hydatidiform Mole

MedGen UID:
1792955
Concept ID:
C5556514
Neoplastic Process

Definition

The spread of abnormal molar chorionic villi from an invasive hydatidiform mole in the uterine cavity to other anatomic sites, usually the vaginal wall and pelvis. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Lewis JL Jr
Cancer 1976 Jul;38(1 SUPPL):620-6. doi: 10.1002/1097-0142(197607)38:1<620::aid-cncr2820380187>3.0.co;2-p. PMID: 179695

Recent clinical studies

Etiology

Lukinovic N, Malovrh EP, Takac I, Sobocan M, Knez J
Radiol Oncol 2022 Dec 1;56(4):430-439. Epub 2022 Oct 27 doi: 10.2478/raon-2022-0038. PMID: 36286620Free PMC Article
Lok C, Frijstein M, van Trommel N
Best Pract Res Clin Obstet Gynaecol 2021 Jul;74:42-52. Epub 2020 Dec 21 doi: 10.1016/j.bpobgyn.2020.12.001. PMID: 33422446
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Smith HO, Kohorn E, Cole LA
Obstet Gynecol Clin North Am 2005 Dec;32(4):661-84. doi: 10.1016/j.ogc.2005.08.001. PMID: 16310678
Rustin GJ, Bagshawe KD
Crit Rev Oncol Hematol 1985;3(2):103-42. doi: 10.1016/s1040-8428(85)80022-6. PMID: 2992827

Diagnosis

Lukinovic N, Malovrh EP, Takac I, Sobocan M, Knez J
Radiol Oncol 2022 Dec 1;56(4):430-439. Epub 2022 Oct 27 doi: 10.2478/raon-2022-0038. PMID: 36286620Free PMC Article
Lok C, Frijstein M, van Trommel N
Best Pract Res Clin Obstet Gynaecol 2021 Jul;74:42-52. Epub 2020 Dec 21 doi: 10.1016/j.bpobgyn.2020.12.001. PMID: 33422446
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Korenaga TK, Tewari KS
Gynecol Oncol 2020 Jun;157(3):799-809. Epub 2020 Apr 5 doi: 10.1016/j.ygyno.2020.03.015. PMID: 32268951Free PMC Article
Lin LH, Polizio R, Fushida K, Francisco RPV
Semin Ultrasound CT MR 2019 Aug;40(4):332-349. Epub 2019 Mar 5 doi: 10.1053/j.sult.2019.03.002. PMID: 31375173

Therapy

Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Gerulath AH, Ehlen TG, Bessette P, Jolicoeur L, Savoie R; Society of Obstetricians and Gynaecologists of Canada; Gynaecologic Oncologists of Canada; Society of Canadian Colposcopists
J Obstet Gynaecol Can 2002 May;24(5):434-46. PMID: 12196865
Currie TH
Semin Oncol Nurs 1990 Aug;6(3):228-36. doi: 10.1016/0749-2081(90)90007-r. PMID: 2169068
Rustin GJ, Bagshawe KD
Crit Rev Oncol Hematol 1985;3(2):103-42. doi: 10.1016/s1040-8428(85)80022-6. PMID: 2992827
Hilgers RD, Lewis JL Jr
Gynecol Oncol 1974 Dec;2(4):460-75. doi: 10.1016/0090-8258(74)90055-9. PMID: 4376997

Prognosis

Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Korenaga TK, Tewari KS
Gynecol Oncol 2020 Jun;157(3):799-809. Epub 2020 Apr 5 doi: 10.1016/j.ygyno.2020.03.015. PMID: 32268951Free PMC Article
Allen SD, Lim AK, Seckl MJ, Blunt DM, Mitchell AW
Clin Radiol 2006 Apr;61(4):301-13. doi: 10.1016/j.crad.2005.12.003. PMID: 16546459
Smith HO, Kohorn E, Cole LA
Obstet Gynecol Clin North Am 2005 Dec;32(4):661-84. doi: 10.1016/j.ogc.2005.08.001. PMID: 16310678
Rustin GJ, Bagshawe KD
Crit Rev Oncol Hematol 1985;3(2):103-42. doi: 10.1016/s1040-8428(85)80022-6. PMID: 2992827

Clinical prediction guides

Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P
J Obstet Gynaecol Can 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. PMID: 33384141
Tsakiridis I, Giouleka S, Kalogiannidis I, Mamopoulos A, Athanasiadis A, Dagklis T
Obstet Gynecol Surv 2020 Dec;75(12):747-756. doi: 10.1097/OGX.0000000000000848. PMID: 33369685
Bolze PA, Attia J, Massardier J, Seckl MJ, Massuger L, van Trommel N, Niemann I, Hajri T, Schott AM, Golfier F; EOTTD group
Eur J Cancer 2015 Sep;51(13):1725-31. Epub 2015 Jun 16 doi: 10.1016/j.ejca.2015.05.026. PMID: 26092638
Allen SD, Lim AK, Seckl MJ, Blunt DM, Mitchell AW
Clin Radiol 2006 Apr;61(4):301-13. doi: 10.1016/j.crad.2005.12.003. PMID: 16546459
Soper JT
Curr Opin Obstet Gynecol 1990 Feb;2(1):92-7. PMID: 1966319

Recent systematic reviews

Deng L, Zhang J, Wu T, Lawrie TA
Cochrane Database Syst Rev 2013 Jan 31;2013(1):CD005196. doi: 10.1002/14651858.CD005196.pub4. PMID: 23440800Free PMC Article

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