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Major Salivary Gland Squamous Cell Carcinoma

MedGen UID:
1793310
•Concept ID:
C5556869
•
Neoplastic Process

Definition

A squamous cell carcinoma that arises from the parotid or submandibular gland. [from NCI]

Professional guidelines

PubMed

Metastatic cutaneous squamous cell carcinoma to the parotid: Adjuvant radiotherapy and treatment outcomes.
Hu M, Kim ANH, Emeto TI, Collins M, Chopping A, Lin C
J Med Radiat Sci 2023 Jun;70(2):161-170. Epub 2023 Feb 15 doi: 10.1002/jmrs.650. PMID: 36790039Free PMC Article
A review of diffusion-weighted magnetic resonance imaging in head and neck cancer patients for treatment evaluation and prediction of radiation-induced xerostomia.
Ermongkonchai T, Khor R, Wada M, Lau E, Xing DT, Ng SP
Radiat Oncol 2023 Jan 30;18(1):20. doi: 10.1186/s13014-022-02178-0. PMID: 36710364Free PMC Article
Pediatric head and neck squamous cell carcinoma: Patient demographics, treatment trends and outcomes.
Modh A, Gayar OH, Elshaikh MA, Paulino AC, Siddiqui F
Int J Pediatr Otorhinolaryngol 2018 Mar;106:21-25. Epub 2018 Jan 3 doi: 10.1016/j.ijporl.2017.12.032. PMID: 29447885

Recent clinical studies

Etiology

Diagnostic Accuracy Of Fine Needle Aspiration Cytology In Comparison To Open Biopsy For Lesions Of Oral Cavity In COVID-19 Era.
Ahmad SS, Zulfiqar G, Imran M
J Pak Med Assoc 2023 Oct;73(10):2023-2028. doi: 10.47391/JPMA.7610. PMID: 37876064
Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
The importance of flaps in reconstruction of locoregionally advanced lateral skull-base cancer defects: a tertiary otorhinolaryngology referral centre experience.
Vozel D, Pukl P, Groselj A, Anicin A, Strojan P, Battelino S
Radiol Oncol 2021 Aug 10;55(3):323-332. doi: 10.2478/raon-2021-0012. PMID: 33735947Free PMC Article
Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer.
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Facial nerve function in 100 consecutive parotidectomies.
Nichols RD, Stine PH, Bartschi LR
Laryngoscope 1979 Dec;89(12):1930-4. doi: 10.1288/00005537-197912000-00005. PMID: 229363

Diagnosis

Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
Pleomorphic adenoma: the great mimicker of malignancy.
Hernandez-Prera JC, Skálová A, Franchi A, Rinaldo A, Vander Poorten V, Zbären P, Ferlito A, Wenig BM
Histopathology 2021 Sep;79(3):279-290. Epub 2021 Apr 22 doi: 10.1111/his.14322. PMID: 33368685
CT and MR imaging findings of palatal tumors.
Kato H, Kanematsu M, Makita H, Kato K, Hatakeyama D, Shibata T, Mizuta K, Aoki M
Eur J Radiol 2014 Mar;83(3):e137-46. Epub 2013 Dec 12 doi: 10.1016/j.ejrad.2013.11.028. PMID: 24377674
Isolation of circulating microRNA in saliva.
Gallo A, Alevizos I
Methods Mol Biol 2013;1024:183-90. doi: 10.1007/978-1-62703-453-1_14. PMID: 23719951
The role of electron microscopy in the diagnosis of tumours of the head and neck.
Fisher C, Flood LM, Ramsey AD
J Laryngol Otol 1992 May;106(5):403-8. doi: 10.1017/s002221510011967x. PMID: 1613365

Therapy

Diagnostic Accuracy Of Fine Needle Aspiration Cytology In Comparison To Open Biopsy For Lesions Of Oral Cavity In COVID-19 Era.
Ahmad SS, Zulfiqar G, Imran M
J Pak Med Assoc 2023 Oct;73(10):2023-2028. doi: 10.47391/JPMA.7610. PMID: 37876064
Oral chronic graft-versus-host disease: current pathogenesis, therapy, and research.
Mays JW, Fassil H, Edwards DA, Pavletic SZ, Bassim CW
Oral Dis 2013 May;19(4):327-46. Epub 2012 Oct 28 doi: 10.1111/odi.12028. PMID: 23107104Free PMC Article
Type of food and risk of oral cancer.
Taghavi N, Yazdi I
Arch Iran Med 2007 Apr;10(2):227-32. PMID: 17367228
Experience with CHART.
Saunders MI, Dische S, Grosch EJ, Fermont DC, Ashford RF, Maher EJ, Makepeace AR
Int J Radiat Oncol Biol Phys 1991 Aug;21(3):871-8. doi: 10.1016/0360-3016(91)90722-g. PMID: 1651312
Recurrences from malignant parotid salivary gland tumors.
Kagan AR, Nussbaum H, Handler S, Shapiro R, Gilbert HA, Jacobs M, Miles JW, Chan PY, Calcaterra T
Cancer 1976 Jun;37(6):2600-4. doi: 10.1002/1097-0142(197606)37:6<2600::aid-cncr2820370606>3.0.co;2-d. PMID: 949679

Prognosis

Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
The importance of flaps in reconstruction of locoregionally advanced lateral skull-base cancer defects: a tertiary otorhinolaryngology referral centre experience.
Vozel D, Pukl P, Groselj A, Anicin A, Strojan P, Battelino S
Radiol Oncol 2021 Aug 10;55(3):323-332. doi: 10.2478/raon-2021-0012. PMID: 33735947Free PMC Article
Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer.
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Isolation of circulating microRNA in saliva.
Gallo A, Alevizos I
Methods Mol Biol 2013;1024:183-90. doi: 10.1007/978-1-62703-453-1_14. PMID: 23719951
Perineural tumor spread.
Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E
Neuroimaging Clin N Am 2008 May;18(2):413-29, xi. doi: 10.1016/j.nic.2008.01.001. PMID: 18466839

Clinical prediction guides

Metastatic cutaneous squamous cell carcinoma to the parotid: Adjuvant radiotherapy and treatment outcomes.
Hu M, Kim ANH, Emeto TI, Collins M, Chopping A, Lin C
J Med Radiat Sci 2023 Jun;70(2):161-170. Epub 2023 Feb 15 doi: 10.1002/jmrs.650. PMID: 36790039Free PMC Article
Nomogram-Based Prediction of Overall and Disease-Specific Survival in Patients With Postoperative Major Salivary Gland Squamous Cell Carcinoma.
Li L, Zhang D, Ma F
Technol Cancer Res Treat 2022 Jan-Dec;21:15330338221117405. doi: 10.1177/15330338221117405. PMID: 35950233Free PMC Article
Clinical outcome and comparison between squamous and non-squamous cell carcinoma of the larynx.
Chen L, Deng W, Li C, Lau H, Tao L, Wang S, Zhou L, Zhang M
Acta Otolaryngol 2020 Feb;140(2):195-201. Epub 2019 Dec 18 doi: 10.1080/00016489.2019.1700305. PMID: 31852360
Necrotising sialometaplasia: a diagnostic perplexity? An innocent entity to malignant masquerade.
Swarup N, Nayak MT, Chowdhary Z, Chandarani S
J Exp Ther Oncol 2018 May;12(3):185-188. PMID: 29790307
Concurrent loss of heterozygosity and copy number analysis in adenoid cystic carcinoma by SNP genotyping arrays.
Yu Y, Baras AS, Shirasuna K, Frierson HF Jr, Moskaluk CA
Lab Invest 2007 May;87(5):430-9. Epub 2007 Mar 19 doi: 10.1038/labinvest.3700536. PMID: 17372589

Recent systematic reviews

Saliva as a Diagnostic Tool in Oral Squamous Cell Carcinoma - a Systematic Review with Meta Analysis.
Hema Shree K, Ramani P, Sherlin H, Sukumaran G, Jeyaraj G, Don KR, Santhanam A, Ramasubramanian A, Sundar R
Pathol Oncol Res 2019 Apr;25(2):447-453. Epub 2019 Feb 2 doi: 10.1007/s12253-019-00588-2. PMID: 30712193
Paraneoplastic syndromes in patients with primary oral cancers: a systematic review.
Chapireau D, Adlam D, Cameron M, Thompson M
Br J Oral Maxillofac Surg 2010 Jul;48(5):338-44. Epub 2009 Oct 14 doi: 10.1016/j.bjoms.2009.08.025. PMID: 19833419

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