U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
Image
Image from GeneReviews
details

Dilated cardiomyopathy 1B(CMD1B)

MedGen UID:
1814491
•Concept ID:
C5700078
•
Disease or Syndrome
Synonyms: CARDIOMYOPATHY, FAMILIAL DILATED; CMD1B
 
Monarch Initiative: MONDO:0010951
OMIM®: 600884

Definition

A dilated cardiomyopathy that has material basis in variation in the chromosome region 9q13. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines

PubMed

Myocardial biopsy based classification and treatment in patients with dilated cardiomyopathy.
Zimmermann O, Kochs M, Zwaka TP, Kaya Z, Lepper PM, Bienek-Ziolkowski M, Hoher M, Hombach V, Torzewski J
Int J Cardiol 2005 Sep 15;104(1):92-100. doi: 10.1016/j.ijcard.2005.02.052. PMID: 16137516

Recent clinical studies

Etiology

Matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, B⁺ tenascin-C and ED-A⁺ fibronectin in dilated cardiomyopathy: potential impact on disease progression and patients' prognosis.
Franz M, Berndt A, Neri D, Galler K, Grün K, Porrmann C, Reinbothe F, Mall G, Schlattmann P, Renner A, Figulla HR, Jung C, Küthe F
Int J Cardiol 2013 Oct 15;168(6):5344-51. Epub 2013 Aug 15 doi: 10.1016/j.ijcard.2013.08.005. PMID: 23998545
Arrhythmias in the muscular dystrophies.
Groh WJ
Heart Rhythm 2012 Nov;9(11):1890-5. Epub 2012 Jun 30 doi: 10.1016/j.hrthm.2012.06.038. PMID: 22760083
A negative screen for mutations in calstabin 1 and 2 genes in patients with dilated cardiomyopathy.
Biagi DG, Mill JG, Mansur AJ, Krieger JE, Pereira AC
J Negat Results Biomed 2012 Jan 11;11:4. doi: 10.1186/1477-5751-11-4. PMID: 22236651Free PMC Article
Interferon beta-1b therapy in chronic viral dilated cardiomyopathy--is there a role for specific therapy?
Zimmermann O, Rodewald C, Radermacher M, Vetter M, Wiehe JM, Bienek-Ziolkowski M, Hombach V, Torzewski J
J Card Fail 2010 Apr;16(4):348-56. Epub 2010 Feb 7 doi: 10.1016/j.cardfail.2009.12.016. PMID: 20350703
Dystrophies and heart disease.
Cox GF, Kunkel LM
Curr Opin Cardiol 1997 May;12(3):329-43. PMID: 9243091

Diagnosis

A 52-year-old woman with ventricular tachycardia.
Fidalgo A, Fernandez-Friera L, Solis J
Heart 2018 Dec;104(24):2025-2043. Epub 2018 Sep 4 doi: 10.1136/heartjnl-2018-313347. PMID: 30181199
Predictors of disease progression in pediatric dilated cardiomyopathy.
Molina KM, Shrader P, Colan SD, Mital S, Margossian R, Sleeper LA, Shirali G, Barker P, Canter CE, Altmann K, Radojewski E, Tierney ES, Rychik J, Tani LY; Pediatric Heart Network Investigators
Circ Heart Fail 2013 Nov;6(6):1214-22. Epub 2013 Oct 16 doi: 10.1161/CIRCHEARTFAILURE.113.000125. PMID: 24132734Free PMC Article
Diagnostic value of rigid body rotation in noncompaction cardiomyopathy.
van Dalen BM, Caliskan K, Soliman OI, Kauer F, van der Zwaan HB, Vletter WB, van Vark LC, Ten Cate FJ, Geleijnse ML
J Am Soc Echocardiogr 2011 May;24(5):548-55. Epub 2011 Feb 22 doi: 10.1016/j.echo.2011.01.002. PMID: 21345651
Laminopathies affecting skeletal and cardiac muscles: clinical and pathophysiological aspects.
Decostre V, Ben Yaou R, Bonne G
Acta Myol 2005 Oct;24(2):104-9. PMID: 16550926
Dystrophies and heart disease.
Cox GF, Kunkel LM
Curr Opin Cardiol 1997 May;12(3):329-43. PMID: 9243091

Therapy

Transthoracic echocardiography: from guidelines for humans to cardiac ultrasound of the heart in rats.
Sztechman D, Żera T, Czarzasta K, Wojciechowska M, Szczepańska-Sadowska E, Cudnoch-Jędrzejewska A
Physiol Meas 2020 Nov 9;41(10):10TR02. doi: 10.1088/1361-6579/abb3a3. PMID: 33164918
Predictors of disease progression in pediatric dilated cardiomyopathy.
Molina KM, Shrader P, Colan SD, Mital S, Margossian R, Sleeper LA, Shirali G, Barker P, Canter CE, Altmann K, Radojewski E, Tierney ES, Rychik J, Tani LY; Pediatric Heart Network Investigators
Circ Heart Fail 2013 Nov;6(6):1214-22. Epub 2013 Oct 16 doi: 10.1161/CIRCHEARTFAILURE.113.000125. PMID: 24132734Free PMC Article
Interferon beta-1b therapy in chronic viral dilated cardiomyopathy--is there a role for specific therapy?
Zimmermann O, Rodewald C, Radermacher M, Vetter M, Wiehe JM, Bienek-Ziolkowski M, Hombach V, Torzewski J
J Card Fail 2010 Apr;16(4):348-56. Epub 2010 Feb 7 doi: 10.1016/j.cardfail.2009.12.016. PMID: 20350703
Myocardial biopsy based classification and treatment in patients with dilated cardiomyopathy.
Zimmermann O, Kochs M, Zwaka TP, Kaya Z, Lepper PM, Bienek-Ziolkowski M, Hoher M, Hombach V, Torzewski J
Int J Cardiol 2005 Sep 15;104(1):92-100. doi: 10.1016/j.ijcard.2005.02.052. PMID: 16137516
Comparison of left ventricular systolic and diastolic function in patients with idiopathic dilated cardiomyopathy and mild heart failure versus those with severe heart failure.
Richartz BM, Werner GS, Ferrari M, Figulla HR
Am J Cardiol 2002 Aug 15;90(4):390-4. doi: 10.1016/s0002-9149(02)02495-5. PMID: 12161228

Prognosis

Urinary Proteomics in Predicting Heart Transplantation Outcomes (uPROPHET)-Rationale and database description.
Huang QF, Trenson S, Zhang ZY, Yang WY, Van Aelst L, Nkuipou-Kenfack E, Wei FF, Mujaj B, Thijs L, Ciarka A, Zoidakis J, Droogné W, Vlahou A, Janssens S, Vanhaecke J, Van Cleemput J, Staessen JA
PLoS One 2017;12(9):e0184443. Epub 2017 Sep 7 doi: 10.1371/journal.pone.0184443. PMID: 28880921Free PMC Article
Matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, B⁺ tenascin-C and ED-A⁺ fibronectin in dilated cardiomyopathy: potential impact on disease progression and patients' prognosis.
Franz M, Berndt A, Neri D, Galler K, Grün K, Porrmann C, Reinbothe F, Mall G, Schlattmann P, Renner A, Figulla HR, Jung C, Küthe F
Int J Cardiol 2013 Oct 15;168(6):5344-51. Epub 2013 Aug 15 doi: 10.1016/j.ijcard.2013.08.005. PMID: 23998545
Interferon beta-1b therapy in chronic viral dilated cardiomyopathy--is there a role for specific therapy?
Zimmermann O, Rodewald C, Radermacher M, Vetter M, Wiehe JM, Bienek-Ziolkowski M, Hombach V, Torzewski J
J Card Fail 2010 Apr;16(4):348-56. Epub 2010 Feb 7 doi: 10.1016/j.cardfail.2009.12.016. PMID: 20350703
Prognostic role of myocardial tumor necrosis factor-alpha and terminal complement complex expression in patients with dilated cardiomyopathy.
Zimmermann O, Kochs M, Zwaka TP, Bienek-Ziolkowski M, Höher M, Hombach V, Torzewski J
Eur J Heart Fail 2007 Jan;9(1):51-4. Epub 2006 May 26 doi: 10.1016/j.ejheart.2006.04.001. PMID: 16730227
Myocardial biopsy based classification and treatment in patients with dilated cardiomyopathy.
Zimmermann O, Kochs M, Zwaka TP, Kaya Z, Lepper PM, Bienek-Ziolkowski M, Hoher M, Hombach V, Torzewski J
Int J Cardiol 2005 Sep 15;104(1):92-100. doi: 10.1016/j.ijcard.2005.02.052. PMID: 16137516

Clinical prediction guides

Urinary Proteomics in Predicting Heart Transplantation Outcomes (uPROPHET)-Rationale and database description.
Huang QF, Trenson S, Zhang ZY, Yang WY, Van Aelst L, Nkuipou-Kenfack E, Wei FF, Mujaj B, Thijs L, Ciarka A, Zoidakis J, Droogné W, Vlahou A, Janssens S, Vanhaecke J, Van Cleemput J, Staessen JA
PLoS One 2017;12(9):e0184443. Epub 2017 Sep 7 doi: 10.1371/journal.pone.0184443. PMID: 28880921Free PMC Article
Predictors of disease progression in pediatric dilated cardiomyopathy.
Molina KM, Shrader P, Colan SD, Mital S, Margossian R, Sleeper LA, Shirali G, Barker P, Canter CE, Altmann K, Radojewski E, Tierney ES, Rychik J, Tani LY; Pediatric Heart Network Investigators
Circ Heart Fail 2013 Nov;6(6):1214-22. Epub 2013 Oct 16 doi: 10.1161/CIRCHEARTFAILURE.113.000125. PMID: 24132734Free PMC Article
Matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, B⁺ tenascin-C and ED-A⁺ fibronectin in dilated cardiomyopathy: potential impact on disease progression and patients' prognosis.
Franz M, Berndt A, Neri D, Galler K, Grün K, Porrmann C, Reinbothe F, Mall G, Schlattmann P, Renner A, Figulla HR, Jung C, Küthe F
Int J Cardiol 2013 Oct 15;168(6):5344-51. Epub 2013 Aug 15 doi: 10.1016/j.ijcard.2013.08.005. PMID: 23998545
Different expression of adrenoceptors and GRKs in the human myocardium depends on heart failure etiology and correlates to clinical variables.
Montó F, Oliver E, Vicente D, Rueda J, Agüero J, Almenar L, Ivorra MD, Barettino D, D'Ocon P
Am J Physiol Heart Circ Physiol 2012 Aug 1;303(3):H368-76. Epub 2012 Jun 8 doi: 10.1152/ajpheart.01061.2011. PMID: 22685168
The nuclear muscular dystrophies.
Wehnert MS, Bonne G
Semin Pediatr Neurol 2002 Jun;9(2):100-7. doi: 10.1053/spen.2002.33806. PMID: 12138994

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...