U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pineocytoma

MedGen UID:
183004
•Concept ID:
C0917890
•
Neoplastic Process
Synonyms: Pinealocytoma; Pineocytoma (disease)
SNOMED CT: Pineocytoma (89096009); Pineocytoma (1156473003)
 
HPO: HP:0030407
Monarch Initiative: MONDO:0016723
Orphanet: ORPHA251912

Definition

A type of pineal parenchymal cell neoplasm that is a mature well-differentiated tumor (WHO grade I). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPineocytoma
Follow this link to review classifications for Pineocytoma in Orphanet.

Professional guidelines

PubMed

Role of radiosurgery in the management of pineal region tumours: indications, method, outcome.
Balossier A, Blond S, Touzet G, Sarrazin T, Lartigau E, Reyns N
Neurochirurgie 2015 Apr-Jun;61(2-3):216-22. Epub 2014 May 27 doi: 10.1016/j.neuchi.2013.11.007. PMID: 24874722
Pineal tumors: analysis of treatment results in 20 patients.
Amendola BE, Wolf A, Coy SR, Amendola MA, Eber D
J Neurosurg 2005 Jan;102 Suppl:175-9. doi: 10.3171/jns.2005.102.s_supplement.0175. PMID: 15662805
The role of radiosurgery for the treatment of pineal parenchymal tumors.
Hasegawa T, Kondziolka D, Hadjipanayis CG, Flickinger JC, Lunsford LD
Neurosurgery 2002 Oct;51(4):880-9. doi: 10.1097/00006123-200210000-00006. PMID: 12234394

Recent clinical studies

Etiology

Third ventricular meningiomas.
Li P, Diao X, Bi Z, Hao S, Ren X, Zhang J, Xing J
J Clin Neurosci 2015 Nov;22(11):1776-84. Epub 2015 Aug 29 doi: 10.1016/j.jocn.2015.05.025. PMID: 26455422
Contemporary management of pineocytoma.
Clark AJ, Sughrue ME, Aranda D, Parsa AT
Neurosurg Clin N Am 2011 Jul;22(3):403-7, ix. Epub 2011 Jun 16 doi: 10.1016/j.nec.2011.05.004. PMID: 21801989
Tumor control after surgery and radiotherapy for pineocytoma.
Clark AJ, Ivan ME, Sughrue ME, Yang I, Aranda D, Han SJ, Kane AJ, Parsa AT
J Neurosurg 2010 Aug;113(2):319-24. doi: 10.3171/2009.12.JNS091683. PMID: 20136388
Pineocytomas.
Disclafani A, Hudgins RJ, Edwards MS, Wara W, Wilson CB, Levin VA
Cancer 1989 Jan 15;63(2):302-4. doi: 10.1002/1097-0142(19890115)63:2<302::aid-cncr2820630216>3.0.co;2-d. PMID: 2910435
The separation of pineocytoma from pineoblastoma.
Borit A, Blackwood W, Mair WG
Cancer 1980 Mar 15;45(6):1408-18. doi: 10.1002/1097-0142(19800315)45:6<1408::aid-cncr2820450619>3.0.co;2-0. PMID: 6986979

Diagnosis

Pineocytoma in a child with Pallister-Killian syndrome: a case report and review of the literature.
De Martino L, Russo C, Bifano D, Quaglietta L, Spennato P, Cinalli G
Childs Nerv Syst 2024 Aug;40(8):2619-2623. Epub 2024 Apr 30 doi: 10.1007/s00381-024-06426-4. PMID: 38689102
Third ventricular meningiomas.
Li P, Diao X, Bi Z, Hao S, Ren X, Zhang J, Xing J
J Clin Neurosci 2015 Nov;22(11):1776-84. Epub 2015 Aug 29 doi: 10.1016/j.jocn.2015.05.025. PMID: 26455422
Familial pineocytoma.
Gempt J, Ringel F, Oexle K, Delbridge C, Förschler A, Schlegel J, Meyer B, Schmidt-Graf F
Acta Neurochir (Wien) 2012 Aug;154(8):1413-6. Epub 2012 Jun 15 doi: 10.1007/s00701-012-1402-5. PMID: 22699425
Pineocytomas.
Disclafani A, Hudgins RJ, Edwards MS, Wara W, Wilson CB, Levin VA
Cancer 1989 Jan 15;63(2):302-4. doi: 10.1002/1097-0142(19890115)63:2<302::aid-cncr2820630216>3.0.co;2-d. PMID: 2910435
The separation of pineocytoma from pineoblastoma.
Borit A, Blackwood W, Mair WG
Cancer 1980 Mar 15;45(6):1408-18. doi: 10.1002/1097-0142(19800315)45:6<1408::aid-cncr2820450619>3.0.co;2-0. PMID: 6986979

Therapy

Usefulness and safety from stereotactic biopsy in posterior fossa lesions in adult patients.
Moreno-Jiménez S, Martínez-Vaca N, Pérez-Aguilar B, Gómez-Calva B, Díaz-Chávez JJ, Mondragón-Soto MG
Cir Cir 2019;87(5):554-558. doi: 10.24875/CIRU.19000717. PMID: 31448801
Safety and diagnostic accuracy of neuroendoscopic biopsies: an international multicenter study.
Constantini S, Mohanty A, Zymberg S, Cavalheiro S, Mallucci C, Hellwig D, Ersahin Y, Mori H, Mascari C, Val JA, Wagner W, Kulkarni AV, Sgouros S, Oi S
J Neurosurg Pediatr 2013 Jun;11(6):704-9. Epub 2013 Apr 12 doi: 10.3171/2013.3.PEDS12416. PMID: 23581635
Radiosurgery for radiosurgery-induced cavernous malformation.
Park YS, Kim SH, Chang JH, Chang JW, Park YG
World Neurosurg 2011 Jan;75(1):94-8. doi: 10.1016/j.wneu.2010.09.017. PMID: 21492671
Therapeutic strategies and surgical results for pineal region tumours.
Tamaki N, Yin D
J Clin Neurosci 2000 Mar;7(2):125-8. doi: 10.1054/jocn.1999.0164. PMID: 10844797
Neuroendoscopic approach to intraventricular lesions.
Gaab MR, Schroeder HW
J Neurosurg 1998 Mar;88(3):496-505. doi: 10.3171/jns.1998.88.3.0496. PMID: 9488304

Prognosis

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Third ventricular meningiomas.
Li P, Diao X, Bi Z, Hao S, Ren X, Zhang J, Xing J
J Clin Neurosci 2015 Nov;22(11):1776-84. Epub 2015 Aug 29 doi: 10.1016/j.jocn.2015.05.025. PMID: 26455422
Contemporary management of pineocytoma.
Clark AJ, Sughrue ME, Aranda D, Parsa AT
Neurosurg Clin N Am 2011 Jul;22(3):403-7, ix. Epub 2011 Jun 16 doi: 10.1016/j.nec.2011.05.004. PMID: 21801989
Pineocytomas.
Disclafani A, Hudgins RJ, Edwards MS, Wara W, Wilson CB, Levin VA
Cancer 1989 Jan 15;63(2):302-4. doi: 10.1002/1097-0142(19890115)63:2<302::aid-cncr2820630216>3.0.co;2-d. PMID: 2910435
The separation of pineocytoma from pineoblastoma.
Borit A, Blackwood W, Mair WG
Cancer 1980 Mar 15;45(6):1408-18. doi: 10.1002/1097-0142(19800315)45:6<1408::aid-cncr2820450619>3.0.co;2-0. PMID: 6986979

Clinical prediction guides

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Concomitant, Single Burr Hole Endoscopic Third Ventriculostomy and Tumor Biopsy for Pineal Lesions: Feasibility, Safety, and Benefits.
Leone A, Colamaria A, Fochi NP, Di Napoli V, Blagia M, Sacco M, Winkler G, Spetzger U, Almerayed W, Carbone F
World Neurosurg 2023 May;173:5-11. Epub 2023 Feb 9 doi: 10.1016/j.wneu.2023.01.082. PMID: 36764448
Third ventricular meningiomas.
Li P, Diao X, Bi Z, Hao S, Ren X, Zhang J, Xing J
J Clin Neurosci 2015 Nov;22(11):1776-84. Epub 2015 Aug 29 doi: 10.1016/j.jocn.2015.05.025. PMID: 26455422
Pathology of pineal parenchymal tumors.
Sato K, Kubota T
Prog Neurol Surg 2009;23:12-25. Epub 2009 Mar 23 doi: 10.1159/000210050. PMID: 19329858
Pathology of pineal region tumors.
Hirato J, Nakazato Y
J Neurooncol 2001 Sep;54(3):239-49. doi: 10.1023/a:1012721723387. PMID: 11767290

Recent systematic reviews

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Tumor control after surgery and radiotherapy for pineocytoma.
Clark AJ, Ivan ME, Sughrue ME, Yang I, Aranda D, Han SJ, Kane AJ, Parsa AT
J Neurosurg 2010 Aug;113(2):319-24. doi: 10.3171/2009.12.JNS091683. PMID: 20136388

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...