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Metastatic Malignant Neoplasm in the Pericardium

MedGen UID:
195778
•Concept ID:
C0685120
•
Neoplastic Process
Synonyms: Metastatic malignant neoplasm of pericardium; Metastatic malignant neoplasm to pericardium; Metastatic Malignant Neoplasm to the Pericardium; Metastatic Neoplasm to the Pericardium; Secondary malignant neoplasm of pericardium
SNOMED CT: Secondary malignant neoplasm of pericardium (94484009); Metastatic malignant neoplasm to pericardium (94484009); Metastatic malignant neoplasm of pericardium (94484009)

Definition

A malignant neoplasm that has spread to the pericardium from another primary anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Pericardium

Professional guidelines

PubMed

A Clinico-Pathologic Approach to the Differential Diagnosis of Pericardial Tumors.
Krywanczyk AR, Tan CD, Rodriguez ER
Curr Cardiol Rep 2021 Jul 16;23(9):119. doi: 10.1007/s11886-021-01548-6. PMID: 34269901
Update on diagnosis and management of neoplastic pericardial disease.
Avondo S, Andreis A, Casula M, Imazio M
Expert Rev Cardiovasc Ther 2020 Sep;18(9):615-623. Epub 2020 Aug 25 doi: 10.1080/14779072.2020.1811087. PMID: 32797759
Clinical Utility of [(18)F]FDG-PET /CT in Pericardial Disease.
Kim MS, Kim EK, Choi JY, Oh JK, Chang SA
Curr Cardiol Rep 2019 Aug 2;21(9):107. doi: 10.1007/s11886-019-1193-x. PMID: 31376028

Recent clinical studies

Etiology

Pericardial Mesotheliomas.
Arrossi AV
Adv Anat Pathol 2023 Jul 1;30(4):253-258. Epub 2023 Apr 27 doi: 10.1097/PAP.0000000000000399. PMID: 37104724
Hydrodissection of the Retro-Sternal Space to Protect the Pericardium During Sternal Cryoablation.
Autrusseau PA, Garnon J, Auloge P, Weiss J, Dalili D, Caudrelier J, Cazzato RL, Koch G, Gangi A
Cardiovasc Intervent Radiol 2020 Sep;43(9):1371-1377. Epub 2020 Jul 8 doi: 10.1007/s00270-020-02587-2. PMID: 32642988
Spectrum of CT Findings in Thoracic Extranodal Non-Hodgkin Lymphoma.
Bligh MP, Borgaonkar JN, Burrell SC, MacDonald DA, Manos D
Radiographics 2017 Mar-Apr;37(2):439-461. doi: 10.1148/rg.2017160077. PMID: 28287948
Pathohistological diagnosis and differential diagnosis.
Tischoff I, Neid M, Neumann V, Tannapfel A
Recent Results Cancer Res 2011;189:57-78. doi: 10.1007/978-3-642-10862-4_5. PMID: 21479896
Metastases of the heart and pericardium.
Silvestri F, Bussani R, Pavletic N, Mannone T
G Ital Cardiol 1997 Dec;27(12):1252-5. PMID: 9470058

Diagnosis

Pericardial Mesotheliomas.
Arrossi AV
Adv Anat Pathol 2023 Jul 1;30(4):253-258. Epub 2023 Apr 27 doi: 10.1097/PAP.0000000000000399. PMID: 37104724
Neoplastic Pericardial Disease.
Maleszewski JJ, Anavekar NS
Cardiol Clin 2017 Nov;35(4):589-600. Epub 2017 Sep 6 doi: 10.1016/j.ccl.2017.07.011. PMID: 29025549
Primary pericardial tumors.
Restrepo CS, Vargas D, Ocazionez D, Martínez-Jiménez S, Betancourt Cuellar SL, Gutierrez FR
Radiographics 2013 Oct;33(6):1613-30. doi: 10.1148/rg.336135512. PMID: 24108554
Malignant pericardial effusion.
Burazor I, Imazio M, Markel G, Adler Y
Cardiology 2013;124(4):224-32. Epub 2013 Apr 5 doi: 10.1159/000348559. PMID: 23571453
Neoplastic pericardial disease.
Hancock EW
Cardiol Clin 1990 Nov;8(4):673-82. PMID: 2249221

Therapy

Safety and Effectiveness of Percutaneous Image-Guided Thermal Ablation of Juxtacardiac Lung Tumors.
Murphy MC, Tahir I, Saenger JA, Abrishami Kashani M, Muniappan A, Levesque VM, Shyn PB, Silverman SG, Fintelmann FJ
J Vasc Interv Radiol 2023 May;34(5):750-758. Epub 2023 Jan 24 doi: 10.1016/j.jvir.2023.01.020. PMID: 36707028
The metastatic site does not influence PD-L1 expression in advanced non-small cell lung carcinoma.
Wang H, Agulnik J, Kasymjanova G, Fiset PO, Camilleri-Broet S, Redpath M, Cohen V, Small D, Pepe C, Sakr L, Spatz A
Lung Cancer 2019 Jun;132:36-38. Epub 2019 Apr 8 doi: 10.1016/j.lungcan.2019.04.009. PMID: 31097091
Neoplastic Pericardial Effusion: A Monocentric Retrospective Study.
Di Liso E, Menichetti A, Dieci MV, Ghiotto C, Banzato A, Bianchi A, Pintacuda G, Padovan M, Nappo F, Cumerlato E, Miglietta F, Mioranza E, Zago G, Corti L, Guarneri V, Conte P
J Palliat Med 2019 Jun;22(6):691-695. Epub 2019 Mar 19 doi: 10.1089/jpm.2018.0491. PMID: 30888908
2015 update on the diagnosis and management of neoplastic pericardial disease.
Lestuzzi C, Berretta M, Tomkowski W
Expert Rev Cardiovasc Ther 2015 Apr;13(4):377-89. doi: 10.1586/14779072.2015.1025754. PMID: 25797903
Malignant pericardial effusion.
Burazor I, Imazio M, Markel G, Adler Y
Cardiology 2013;124(4):224-32. Epub 2013 Apr 5 doi: 10.1159/000348559. PMID: 23571453

Prognosis

Pericardial Mesotheliomas.
Arrossi AV
Adv Anat Pathol 2023 Jul 1;30(4):253-258. Epub 2023 Apr 27 doi: 10.1097/PAP.0000000000000399. PMID: 37104724
Comprehensive review of the epidemiology and treatments for malignant adult cardiac tumors.
Taguchi S
Gen Thorac Cardiovasc Surg 2018 May;66(5):257-262. Epub 2018 Mar 28 doi: 10.1007/s11748-018-0912-3. PMID: 29594875
Primary pericardial tumors.
Restrepo CS, Vargas D, Ocazionez D, Martínez-Jiménez S, Betancourt Cuellar SL, Gutierrez FR
Radiographics 2013 Oct;33(6):1613-30. doi: 10.1148/rg.336135512. PMID: 24108554
Malignant pericardial effusion.
Burazor I, Imazio M, Markel G, Adler Y
Cardiology 2013;124(4):224-32. Epub 2013 Apr 5 doi: 10.1159/000348559. PMID: 23571453
Pericardial tumors.
Luk A, Ahn E, Vaideeswar P, Butany JW
Semin Diagn Pathol 2008 Feb;25(1):47-53. doi: 10.1053/j.semdp.2007.12.001. PMID: 18350922

Clinical prediction guides

Primary cardiac and pericardial lymphangiomas: clinical, radiologic, and pathologic characterization derived from an institutional series and review of the literature.
Pichler Sekulic S, Sekulic M
Virchows Arch 2022 Jun;480(6):1211-1221. Epub 2022 Jan 10 doi: 10.1007/s00428-022-03269-9. PMID: 35013774
Clinical Utility of [(18)F]FDG-PET /CT in Pericardial Disease.
Kim MS, Kim EK, Choi JY, Oh JK, Chang SA
Curr Cardiol Rep 2019 Aug 2;21(9):107. doi: 10.1007/s11886-019-1193-x. PMID: 31376028
The metastatic site does not influence PD-L1 expression in advanced non-small cell lung carcinoma.
Wang H, Agulnik J, Kasymjanova G, Fiset PO, Camilleri-Broet S, Redpath M, Cohen V, Small D, Pepe C, Sakr L, Spatz A
Lung Cancer 2019 Jun;132:36-38. Epub 2019 Apr 8 doi: 10.1016/j.lungcan.2019.04.009. PMID: 31097091
Spectrum of malignant pleural and pericardial disease on FDG PET/CT.
Makis W, Ciarallo A, Hickeson M, Rush C, Novales-Diaz JA, Derbekyan V, Laufer J, Stern J, Lisbona R
AJR Am J Roentgenol 2012 Mar;198(3):678-85. doi: 10.2214/AJR.11.7076. PMID: 22358009
Metastases of the heart and pericardium.
Silvestri F, Bussani R, Pavletic N, Mannone T
G Ital Cardiol 1997 Dec;27(12):1252-5. PMID: 9470058

Recent systematic reviews

A Systematic Review and Meta-Analysis of Prevalence and Outcomes of Cardiac Metastasis of Neuroendocrine Malignancies.
Hamza M, Manasrah N, Patel NN, Sattar Y, Patel B
Am J Cardiol 2023 May 1;194:86-92. Epub 2023 Mar 29 doi: 10.1016/j.amjcard.2023.02.011. PMID: 36996525
Primary and metastatic primitive neuroectodermal tumor of the heart: A systematic review.
Hajsadeghi S, Iranpour A, Amouei E, Tehrani NH, Ghavidel A, Ziaie H, Asadi O, Moradians V, Tayebi A, Mestres CA, Manqoutaei SA
Asian Cardiovasc Thorac Ann 2022 Sep;30(7):761-771. Epub 2022 Mar 21 doi: 10.1177/02184923221083434. PMID: 35306869
Intrapericardial instillation of bleomycin prevents recurrence of malignant pericardial effusions: Series of 46 cases and comprehensive literature review.
Lambert A, Salleron J, Kieffer A, Raymond P, Geoffrois L, Gavoille C
Bull Cancer 2020 Jul-Aug;107(7-8):756-762. Epub 2020 Jun 5 doi: 10.1016/j.bulcan.2020.04.010. PMID: 32513434

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