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Malignant Somatostatinoma

MedGen UID:
224755
Concept ID:
C1266015
Neoplastic Process
Synonyms: Delta Cell Carcinoma; Somatostatin cell tumor, malignant; Somatostatinoma, malignant
SNOMED CT: Somatostatin cell tumor, malignant (128643000); Somatostatinoma, malignant (128643000)

Definition

A neuroendocrine tumor arising from delta cells which produce somatostatin. It displays vascular invasion and metastasizes to other anatomic sites. [from NCI]

Professional guidelines

PubMed

Pellegrino F, Granata V, Fusco R, Grassi F, Tafuto S, Perrucci L, Tralli G, Scaglione M
Tomography 2023 Jan 27;9(1):217-246. doi: 10.3390/tomography9010018. PMID: 36828370Free PMC Article
Parbhu SK, Adler DG
Hosp Pract (1995) 2016 Aug;44(3):109-19. Epub 2016 Jul 18 doi: 10.1080/21548331.2016.1210474. PMID: 27404266
Ito T, Igarashi H, Jensen RT
Best Pract Res Clin Gastroenterol 2012 Dec;26(6):737-53. doi: 10.1016/j.bpg.2012.12.003. PMID: 23582916Free PMC Article

Recent clinical studies

Etiology

Prinz RA, Sandberg L
J Med 1984;15(3):177-83. PMID: 6098624

Diagnosis

Theodoraki A, Khoo B, Hamda A, Grillo F, Meyer T, Bouloux PM
Endocr Pract 2010 Sep-Oct;16(5):835-7. doi: 10.4158/EP10109.CR. PMID: 20497932
Suzuki H, Kuwano H, Masuda N, Hashimoto S, Kanoh K, Nomoto K, Shimura T, Katoh H
Hepatogastroenterology 2008 Jul-Aug;55(85):1242-5. PMID: 18795665
Bettini R, Falconi M, Crippa S, Capelli P, Boninsegna L, Pederzoli P
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Schillaci O, Annibale B, Scopinaro F, delle Fave G, Colella AC
J Nucl Med 1997 Jun;38(6):886-7. PMID: 9189135
Abe T, Oshida K, Matsumoto K, Iida M, Sanno N
J Neurosurg 1996 Oct;85(4):681-4. doi: 10.3171/jns.1996.85.4.0681. PMID: 8814175

Therapy

Ozbakir O, Keleştimur F, Oztürk F, Sözüer E, Unal A, Patiroğlu TE, Güven K
Postgrad Med J 1995 Nov;71(841):695-8. doi: 10.1136/pgmj.71.841.695. PMID: 7494779Free PMC Article
Levi S, Bjarnason I, Swinson CM, Polak JM, Murray W, Levi AJ
Digestion 1988;39(1):1-6. doi: 10.1159/000199601. PMID: 2899527

Prognosis

Lin FC, Lin CM, Hsieh CC, Li WY, Wang LS
Am J Clin Oncol 2003 Jun;26(3):270-2. doi: 10.1097/01.COC.0000020584.56294.72. PMID: 12796599

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