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Anaplastic Brain Stem Glioma

MedGen UID:
231067
Concept ID:
C1332280
Neoplastic Process
Synonyms: Anaplastic Brainstem Glioma; Anaplastic Glioma of Brain Stem; Anaplastic Glioma of Brainstem; Anaplastic Glioma of the Brain Stem; Anaplastic Glioma of the Brainstem; Brain Stem Glioma, Grade III; Brainstem Glioma, Grade III; Grade 3 Brain Stem Glioma; Grade 3 Brainstem Glioma; Grade 3 Glioma of Brain Stem; Grade 3 Glioma of Brainstem; Grade 3 Glioma of the Brain Stem; Grade 3 Glioma of the Brainstem; Grade III Brain Stem Glioma; Grade III Brainstem Glioma; Grade III Glioma of Brain Stem; Grade III Glioma of Brainstem; Grade III Glioma of the Brain Stem; Grade III Glioma of the Brainstem; Undifferentiated Brain Stem Glioma; Undifferentiated Brainstem Glioma; Undifferentiated Glioma of Brain Stem; Undifferentiated Glioma of Brainstem; Undifferentiated Glioma of the Brain Stem; Undifferentiated Glioma of the Brainstem

Definition

An anaplastic glioma that arises from the brain stem. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnaplastic Brain Stem Glioma

Professional guidelines

PubMed

Mohme M, Fritzsche FS, Mende KC, Matschke J, Löbel U, Kammler G, Westphal M, Emami P, Martens T
Neurosurg Focus 2018 Jun;44(6):E15. doi: 10.3171/2018.3.FOCUS1850. PMID: 29852760
Duffau H, Taillandier L
Neuro Oncol 2015 Mar;17(3):332-42. Epub 2014 Aug 2 doi: 10.1093/neuonc/nou153. PMID: 25087230Free PMC Article
Driever PH, Knüpfer MM, Cinatl J, Wolff JE
Klin Padiatr 1999 Jul-Aug;211(4):323-8. doi: 10.1055/s-2008-1043809. PMID: 10472571

Recent clinical studies

Etiology

Krystal J, Hanson D, Donnelly D, Atlas M
Pediatr Blood Cancer 2024 Apr;71(4):e30874. Epub 2024 Jan 17 doi: 10.1002/pbc.30874. PMID: 38234020
Guerreiro Stucklin AS, Ryall S, Fukuoka K, Zapotocky M, Lassaletta A, Li C, Bridge T, Kim B, Arnoldo A, Kowalski PE, Zhong Y, Johnson M, Li C, Ramani AK, Siddaway R, Nobre LF, de Antonellis P, Dunham C, Cheng S, Boué DR, Finlay JL, Coven SL, de Prada I, Perez-Somarriba M, Faria CC, Grotzer MA, Rushing E, Sumerauer D, Zamecnik J, Krskova L, Garcia Ariza M, Cruz O, Morales La Madrid A, Solano P, Terashima K, Nakano Y, Ichimura K, Nagane M, Sakamoto H, Gil-da-Costa MJ, Silva R, Johnston DL, Michaud J, Wilson B, van Landeghem FKH, Oviedo A, McNeely PD, Crooks B, Fried I, Zhukova N, Hansford JR, Nageswararao A, Garzia L, Shago M, Brudno M, Irwin MS, Bartels U, Ramaswamy V, Bouffet E, Taylor MD, Tabori U, Hawkins C
Nat Commun 2019 Sep 25;10(1):4343. doi: 10.1038/s41467-019-12187-5. PMID: 31554817Free PMC Article
Cassia GSE, Alves CAPF, Taranath A, López NS, Oztekin O, Gonçalves FG, Patay Z
Top Magn Reson Imaging 2018 Dec;27(6):479-502. doi: 10.1097/RMR.0000000000000184. PMID: 30516696
Venkatesh HS, Tam LT, Woo PJ, Lennon J, Nagaraja S, Gillespie SM, Ni J, Duveau DY, Morris PJ, Zhao JJ, Thomas CJ, Monje M
Nature 2017 Sep 28;549(7673):533-537. Epub 2017 Sep 20 doi: 10.1038/nature24014. PMID: 28959975Free PMC Article
McComb RD, Burger PC
Neurol Clin 1985 Nov;3(4):711-28. PMID: 3001488

Diagnosis

Krystal J, Hanson D, Donnelly D, Atlas M
Pediatr Blood Cancer 2024 Apr;71(4):e30874. Epub 2024 Jan 17 doi: 10.1002/pbc.30874. PMID: 38234020
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
Fares J, Ahmed AU, Ulasov IV, Sonabend AM, Miska J, Lee-Chang C, Balyasnikova IV, Chandler JP, Portnow J, Tate MC, Kumthekar P, Lukas RV, Grimm SA, Adams AK, Hébert CD, Strong TV, Amidei C, Arrieta VA, Zannikou M, Horbinski C, Zhang H, Burdett KB, Curiel DT, Sachdev S, Aboody KS, Stupp R, Lesniak MS
Lancet Oncol 2021 Aug;22(8):1103-1114. Epub 2021 Jun 29 doi: 10.1016/S1470-2045(21)00245-X. PMID: 34214495Free PMC Article
Cassia GSE, Alves CAPF, Taranath A, López NS, Oztekin O, Gonçalves FG, Patay Z
Top Magn Reson Imaging 2018 Dec;27(6):479-502. doi: 10.1097/RMR.0000000000000184. PMID: 30516696
Soffietti R
Expert Opin Pharmacother 2004 Feb;5(2):295-306. doi: 10.1517/14656566.5.2.295. PMID: 14996626

Therapy

Krystal J, Hanson D, Donnelly D, Atlas M
Pediatr Blood Cancer 2024 Apr;71(4):e30874. Epub 2024 Jan 17 doi: 10.1002/pbc.30874. PMID: 38234020
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
Fares J, Ahmed AU, Ulasov IV, Sonabend AM, Miska J, Lee-Chang C, Balyasnikova IV, Chandler JP, Portnow J, Tate MC, Kumthekar P, Lukas RV, Grimm SA, Adams AK, Hébert CD, Strong TV, Amidei C, Arrieta VA, Zannikou M, Horbinski C, Zhang H, Burdett KB, Curiel DT, Sachdev S, Aboody KS, Stupp R, Lesniak MS
Lancet Oncol 2021 Aug;22(8):1103-1114. Epub 2021 Jun 29 doi: 10.1016/S1470-2045(21)00245-X. PMID: 34214495Free PMC Article
Liu H, Sun Q, Sun Y, Zhang J, Yuan H, Pang S, Qi X, Wang H, Zhang M, Zhang H, Yu C, Gu C
Mol Cancer Res 2017 Sep;15(9):1275-1286. Epub 2017 May 23 doi: 10.1158/1541-7786.MCR-17-0105. PMID: 28536141
Soffietti R
Expert Opin Pharmacother 2004 Feb;5(2):295-306. doi: 10.1517/14656566.5.2.295. PMID: 14996626

Prognosis

Krystal J, Hanson D, Donnelly D, Atlas M
Pediatr Blood Cancer 2024 Apr;71(4):e30874. Epub 2024 Jan 17 doi: 10.1002/pbc.30874. PMID: 38234020
Cambruzzi E
Childs Nerv Syst 2018 May;34(5):809-815. Epub 2018 Mar 26 doi: 10.1007/s00381-018-3765-2. PMID: 29582169
Rosager AM, Sørensen MD, Dahlrot RH, Hansen S, Schonberg DL, Rich JN, Lathia JD, Kristensen BW
PLoS One 2017;12(8):e0182954. Epub 2017 Aug 24 doi: 10.1371/journal.pone.0182954. PMID: 28837569Free PMC Article
Soffietti R
Expert Opin Pharmacother 2004 Feb;5(2):295-306. doi: 10.1517/14656566.5.2.295. PMID: 14996626
McComb RD, Burger PC
Neurol Clin 1985 Nov;3(4):711-28. PMID: 3001488

Clinical prediction guides

Trkova K, Sumerauer D, Krskova L, Vicha A, Koblizek M, Votava T, Priban V, Zapotocky M
Childs Nerv Syst 2023 Sep;39(9):2509-2513. Epub 2023 May 11 doi: 10.1007/s00381-023-05976-3. PMID: 37165121Free PMC Article
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
Andromidas F, Atashpanjeh S, Myers AJ, MacKinnon BE, Shaffer MM, Koob AO
Curr Neuropharmacol 2021;19(11):1952-1965. doi: 10.2174/1570159X19666210420095118. PMID: 33881971Free PMC Article
Xu R, Shimizu F, Hovinga K, Beal K, Karimi S, Droms L, Peck KK, Gutin P, Iorgulescu JB, Kaley T, DeAngelis L, Pentsova E, Nolan C, Grommes C, Chan T, Bobrow D, Hormigo A, Cross JR, Wu N, Takebe N, Panageas K, Ivy P, Supko JG, Tabar V, Omuro A
Clin Cancer Res 2016 Oct 1;22(19):4786-4796. Epub 2016 May 6 doi: 10.1158/1078-0432.CCR-16-0048. PMID: 27154916Free PMC Article
Soffietti R
Expert Opin Pharmacother 2004 Feb;5(2):295-306. doi: 10.1517/14656566.5.2.295. PMID: 14996626

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