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Anaplastic Brain Stem Astrocytoma

MedGen UID:
233983
•Concept ID:
C1332279
•
Neoplastic Process
Synonym: Anaplastic Brainstem Astrocytoma

Definition

An anaplastic astrocytoma that arises from the brain stem. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnaplastic Brain Stem Astrocytoma

Professional guidelines

PubMed

Tectal gliomas: assessment of malignant progression, clinical management, and quality of life in a supposedly benign neoplasm.
Mohme M, Fritzsche FS, Mende KC, Matschke J, Löbel U, Kammler G, Westphal M, Emami P, Martens T
Neurosurg Focus 2018 Jun;44(6):E15. doi: 10.3171/2018.3.FOCUS1850. PMID: 29852760
The impact of extent of resection in the management of malignant gliomas of childhood.
Finlay JL, Wisoff JH
Childs Nerv Syst 1999 Nov;15(11-12):786-8. doi: 10.1007/s003810050471. PMID: 10603023
Valproic acid for the treatment of pediatric malignant glioma.
Driever PH, Knüpfer MM, Cinatl J, Wolff JE
Klin Padiatr 1999 Jul-Aug;211(4):323-8. doi: 10.1055/s-2008-1043809. PMID: 10472571

Recent clinical studies

Etiology

Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value.
Rosager AM, Sørensen MD, Dahlrot RH, Hansen S, Schonberg DL, Rich JN, Lathia JD, Kristensen BW
PLoS One 2017;12(8):e0182954. Epub 2017 Aug 24 doi: 10.1371/journal.pone.0182954. PMID: 28837569Free PMC Article
Radiotherapy for high-grade gliomas. Does altered fractionation improve the outcome?
Nieder C, Andratschke N, Wiedenmann N, Busch R, Grosu AL, Molls M
Strahlenther Onkol 2004 Jul;180(7):401-7. doi: 10.1007/s00066-004-1220-7. PMID: 15241527
The impact of extent of resection in the management of malignant gliomas of childhood.
Finlay JL, Wisoff JH
Childs Nerv Syst 1999 Nov;15(11-12):786-8. doi: 10.1007/s003810050471. PMID: 10603023
Brain biopsy using high-field strength interventional magnetic resonance imaging.
Hall WA, Martin AJ, Liu H, Nussbaum ES, Maxwell RE, Truwit CL
Neurosurgery 1999 Apr;44(4):807-13; discussion 813-4. doi: 10.1097/00006123-199904000-00067. PMID: 10201306
Pathologic analysis of primary brain tumors.
McComb RD, Burger PC
Neurol Clin 1985 Nov;3(4):711-28. PMID: 3001488

Diagnosis

Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318
Neural stem cell delivery of an oncolytic adenovirus in newly diagnosed malignant glioma: a first-in-human, phase 1, dose-escalation trial.
Fares J, Ahmed AU, Ulasov IV, Sonabend AM, Miska J, Lee-Chang C, Balyasnikova IV, Chandler JP, Portnow J, Tate MC, Kumthekar P, Lukas RV, Grimm SA, Adams AK, Hébert CD, Strong TV, Amidei C, Arrieta VA, Zannikou M, Horbinski C, Zhang H, Burdett KB, Curiel DT, Sachdev S, Aboody KS, Stupp R, Lesniak MS
Lancet Oncol 2021 Aug;22(8):1103-1114. Epub 2021 Jun 29 doi: 10.1016/S1470-2045(21)00245-X. PMID: 34214495Free PMC Article
Chemotherapy of anaplastic oligodendroglial tumours.
Soffietti R
Expert Opin Pharmacother 2004 Feb;5(2):295-306. doi: 10.1517/14656566.5.2.295. PMID: 14996626
Brain biopsy using high-field strength interventional magnetic resonance imaging.
Hall WA, Martin AJ, Liu H, Nussbaum ES, Maxwell RE, Truwit CL
Neurosurgery 1999 Apr;44(4):807-13; discussion 813-4. doi: 10.1097/00006123-199904000-00067. PMID: 10201306
Pathologic analysis of primary brain tumors.
McComb RD, Burger PC
Neurol Clin 1985 Nov;3(4):711-28. PMID: 3001488

Therapy

Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318
Neural stem cell delivery of an oncolytic adenovirus in newly diagnosed malignant glioma: a first-in-human, phase 1, dose-escalation trial.
Fares J, Ahmed AU, Ulasov IV, Sonabend AM, Miska J, Lee-Chang C, Balyasnikova IV, Chandler JP, Portnow J, Tate MC, Kumthekar P, Lukas RV, Grimm SA, Adams AK, Hébert CD, Strong TV, Amidei C, Arrieta VA, Zannikou M, Horbinski C, Zhang H, Burdett KB, Curiel DT, Sachdev S, Aboody KS, Stupp R, Lesniak MS
Lancet Oncol 2021 Aug;22(8):1103-1114. Epub 2021 Jun 29 doi: 10.1016/S1470-2045(21)00245-X. PMID: 34214495Free PMC Article
Chemotherapy of anaplastic oligodendroglial tumours.
Soffietti R
Expert Opin Pharmacother 2004 Feb;5(2):295-306. doi: 10.1517/14656566.5.2.295. PMID: 14996626
Brain biopsy using high-field strength interventional magnetic resonance imaging.
Hall WA, Martin AJ, Liu H, Nussbaum ES, Maxwell RE, Truwit CL
Neurosurgery 1999 Apr;44(4):807-13; discussion 813-4. doi: 10.1097/00006123-199904000-00067. PMID: 10201306
Chemotherapy for brain tumors.
Pech IV, Peterson K, Cairncross JG
Oncology (Williston Park) 1998 Apr;12(4):537-43, 547; discussion 547-8, 553. PMID: 9575527

Prognosis

Differential expression of stem cell markers in proliferating cells in glioma.
Rehfeld M, Matschke J, Hagel C, Willenborg K, Glatzel M, Bernreuther C
J Cancer Res Clin Oncol 2021 Oct;147(10):2969-2982. Epub 2021 Jun 25 doi: 10.1007/s00432-021-03704-5. PMID: 34170383Free PMC Article
Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value.
Rosager AM, Sørensen MD, Dahlrot RH, Hansen S, Schonberg DL, Rich JN, Lathia JD, Kristensen BW
PLoS One 2017;12(8):e0182954. Epub 2017 Aug 24 doi: 10.1371/journal.pone.0182954. PMID: 28837569Free PMC Article
Radiotherapy for high-grade gliomas. Does altered fractionation improve the outcome?
Nieder C, Andratschke N, Wiedenmann N, Busch R, Grosu AL, Molls M
Strahlenther Onkol 2004 Jul;180(7):401-7. doi: 10.1007/s00066-004-1220-7. PMID: 15241527
Chemotherapy of anaplastic oligodendroglial tumours.
Soffietti R
Expert Opin Pharmacother 2004 Feb;5(2):295-306. doi: 10.1517/14656566.5.2.295. PMID: 14996626
Pathologic analysis of primary brain tumors.
McComb RD, Burger PC
Neurol Clin 1985 Nov;3(4):711-28. PMID: 3001488

Clinical prediction guides

Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318
The Astrogenic Balance in the Aging Brain.
Andromidas F, Atashpanjeh S, Myers AJ, MacKinnon BE, Shaffer MM, Koob AO
Curr Neuropharmacol 2021;19(11):1952-1965. doi: 10.2174/1570159X19666210420095118. PMID: 33881971Free PMC Article
Chemotherapy of anaplastic oligodendroglial tumours.
Soffietti R
Expert Opin Pharmacother 2004 Feb;5(2):295-306. doi: 10.1517/14656566.5.2.295. PMID: 14996626
Valproic acid for the treatment of pediatric malignant glioma.
Driever PH, Knüpfer MM, Cinatl J, Wolff JE
Klin Padiatr 1999 Jul-Aug;211(4):323-8. doi: 10.1055/s-2008-1043809. PMID: 10472571
Brain biopsy using high-field strength interventional magnetic resonance imaging.
Hall WA, Martin AJ, Liu H, Nussbaum ES, Maxwell RE, Truwit CL
Neurosurgery 1999 Apr;44(4):807-13; discussion 813-4. doi: 10.1097/00006123-199904000-00067. PMID: 10201306

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