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Childhood Benign Brain Neoplasm

MedGen UID:
231425
•Concept ID:
C1332482
•
Neoplastic Process
Synonyms: Benign Childhood Brain Neoplasm; Benign Childhood Brain Tumor; Benign Childhood Neoplasm of Brain; Benign Childhood Neoplasm of the Brain; Benign Childhood Tumor of Brain; Benign Childhood Tumor of the Brain; Benign Pediatric Brain Neoplasm; Benign Pediatric Brain Tumor; Benign Pediatric Neoplasm of Brain; Benign Pediatric Neoplasm of the Brain; Benign Pediatric Tumor of Brain; Benign Pediatric Tumor of the Brain

Definition

A childhood neoplasm that arises from the brain and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Advances in the Diagnosis and Treatment of Pediatric Arterial Ischemic Stroke.
Sun LR, Lynch JK
Neurotherapeutics 2023 Apr;20(3):633-654. Epub 2023 Apr 18 doi: 10.1007/s13311-023-01373-5. PMID: 37072548Free PMC Article
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF GROWTH HORMONE DEFICIENCY IN ADULTS AND PATIENTS TRANSITIONING FROM PEDIATRIC TO ADULT CARE.
Yuen KCJ, Biller BMK, Radovick S, Carmichael JD, Jasim S, Pantalone KM, Hoffman AR
Endocr Pract 2019 Nov;25(11):1191-1232. doi: 10.4158/GL-2019-0405. PMID: 31760824
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article

Recent clinical studies

Therapy

Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article
Neurocutaneous Syndromes and Brain Tumors.
Ullrich NJ
J Child Neurol 2016 Oct;31(12):1399-411. Epub 2015 Oct 12 doi: 10.1177/0883073815604220. PMID: 26459515
Craniopharyngioma.
Müller HL
Handb Clin Neurol 2014;124:235-53. doi: 10.1016/B978-0-444-59602-4.00016-2. PMID: 25248591
Dietary therapies for epilepsy.
Kossoff EH, Wang HS
Biomed J 2013 Jan-Feb;36(1):2-8. doi: 10.4103/2319-4170.107152. PMID: 23515147
Optic pathway gliomas.
Avery RA, Fisher MJ, Liu GT
J Neuroophthalmol 2011 Sep;31(3):269-78. doi: 10.1097/WNO.0b013e31822aef82. PMID: 21857190

Prognosis

Epidemiology of Brain and Other CNS Tumors.
Ostrom QT, Francis SS, Barnholtz-Sloan JS
Curr Neurol Neurosci Rep 2021 Nov 24;21(12):68. doi: 10.1007/s11910-021-01152-9. PMID: 34817716Free PMC Article
Pediatric Neuro-Oncology.
Malbari F
Neurol Clin 2021 Aug;39(3):829-845. Epub 2021 Jun 10 doi: 10.1016/j.ncl.2021.04.005. PMID: 34215389
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article
Pediatric brain tumors.
Wells EM, Packer RJ
Continuum (Minneap Minn) 2015 Apr;21(2 Neuro-oncology):373-96. doi: 10.1212/01.CON.0000464176.96311.d1. PMID: 25837902
Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study.
Pearce MS, Salotti JA, Little MP, McHugh K, Lee C, Kim KP, Howe NL, Ronckers CM, Rajaraman P, Sir Craft AW, Parker L, Berrington de González A
Lancet 2012 Aug 4;380(9840):499-505. Epub 2012 Jun 7 doi: 10.1016/S0140-6736(12)60815-0. PMID: 22681860Free PMC Article

Clinical prediction guides

TULIPs decorate the three-dimensional genome of PFA ependymoma.
Johnston MJ, Lee JJY, Hu B, Nikolic A, Hasheminasabgorji E, Baguette A, Paik S, Chen H, Kumar S, Chen CCL, Jessa S, Balin P, Fong V, Zwaig M, Michealraj KA, Chen X, Zhang Y, Varadharajan S, Billon P, Juretic N, Daniels C, Rao AN, Giannini C, Thompson EM, Garami M, Hauser P, Pocza T, Ra YS, Cho BK, Kim SK, Wang KC, Lee JY, Grajkowska W, Perek-Polnik M, Agnihotri S, Mack S, Ellezam B, Weil A, Rich J, Bourque G, Chan JA, Yong VW, Lupien M, Ragoussis J, Kleinman C, Majewski J, Blanchette M, Jabado N, Taylor MD, Gallo M
Cell 2024 Sep 5;187(18):4926-4945.e22. Epub 2024 Jul 9 doi: 10.1016/j.cell.2024.06.023. PMID: 38986619
Posterior fossa tumors in children: current insights.
Formentin C, Joaquim AF, Ghizoni E
Eur J Pediatr 2023 Nov;182(11):4833-4850. Epub 2023 Sep 8 doi: 10.1007/s00431-023-05189-5. PMID: 37679511
Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond.
Kresbach C, Neyazi S, Schüller U
Brain Pathol 2022 Jul;32(4):e13068. Epub 2022 Mar 21 doi: 10.1111/bpa.13068. PMID: 35307892Free PMC Article
Diagnostic criteria for constitutional mismatch repair deficiency syndrome: suggestions of the European consortium 'care for CMMRD' (C4CMMRD).
Wimmer K, Kratz CP, Vasen HF, Caron O, Colas C, Entz-Werle N, Gerdes AM, Goldberg Y, Ilencikova D, Muleris M, Duval A, Lavoine N, Ruiz-Ponte C, Slavc I, Burkhardt B, Brugieres L; EU-Consortium Care for CMMRD (C4CMMRD)
J Med Genet 2014 Jun;51(6):355-65. Epub 2014 Apr 15 doi: 10.1136/jmedgenet-2014-102284. PMID: 24737826
Molecular genetics of gliomas.
Appin CL, Brat DJ
Cancer J 2014 Jan-Feb;20(1):66-72. doi: 10.1097/PPO.0000000000000020. PMID: 24445767

Recent systematic reviews

Risk factors for childhood brain tumours: A systematic review and meta-analysis of observational studies from 1976 to 2022.
Onyije FM, Dolatkhah R, Olsson A, Bouaoun L, Deltour I, Erdmann F, Bonaventure A, Scheurer ME, Clavel J, Schüz J
Cancer Epidemiol 2024 Feb;88:102510. Epub 2023 Dec 5 doi: 10.1016/j.canep.2023.102510. PMID: 38056243Free PMC Article
Seizure outcomes after resection of primary brain tumors in pediatric patients: a systematic review and meta-analysis.
Katlowitz KA, Athukuri P, Sharma H, Dang H, Soni A, Khan AB, Malbari F, Gadgil N, Weiner HL
J Neurooncol 2023 Sep;164(3):525-533. Epub 2023 Sep 14 doi: 10.1007/s11060-023-04446-9. PMID: 37707753
Neurocognitive outcomes in pediatric brain tumors after treatment with proton versus photon radiation: a systematic review and meta-analysis.
Lassaletta Á, Morales JS, Valenzuela PL, Esteso B, Kahalley LS, Mabbott DJ, Unnikrishnan S, Panizo E, Calvo F
World J Pediatr 2023 Aug;19(8):727-740. Epub 2023 May 8 doi: 10.1007/s12519-023-00726-6. PMID: 37154861Free PMC Article
Childhood Brain Tumors: a Systematic Review of the Structural Neuroimaging Literature.
Ailion AS, Hortman K, King TZ
Neuropsychol Rev 2017 Sep;27(3):220-244. Epub 2017 Jun 23 doi: 10.1007/s11065-017-9352-6. PMID: 28646252
Neuropsychiatric presentations and outcomes in children and adolescents with primary brain tumours: Systematic review.
Zyrianova Y, Alexander L, Faruqui R
Brain Inj 2016;30(1):1-9. Epub 2015 Nov 5 doi: 10.3109/02699052.2015.1075590. PMID: 26536821

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