U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Childhood kidney Wilms tumor

MedGen UID:
232073
Concept ID:
C1333015
Neoplastic Process
Synonyms: Childhood Kidney Nephroblastoma; Childhood Kidney Wilms Tumor; childhood kidney Wilms tumor; Childhood Renal Wilms Tumor; childhood renal Wilms tumor; Childhood Renal Wilms' Tumor; childhood renal Wilms' tumor; childhood Wilms tumor
 
Monarch Initiative: MONDO:0024676

Definition

A Wilms tumor of the kidney which occurs in children. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood kidney Wilms tumor

Professional guidelines

PubMed

Lipshultz SE, Law YM, Asante-Korang A, Austin ED, Dipchand AI, Everitt MD, Hsu DT, Lin KY, Price JF, Wilkinson JD, Colan SD
Circulation 2019 Jul 2;140(1):e9-e68. Epub 2019 May 28 doi: 10.1161/CIR.0000000000000682. PMID: 31132865
Oostveen RM, Pritchard-Jones K
Paediatr Drugs 2019 Feb;21(1):1-13. doi: 10.1007/s40272-018-0323-z. PMID: 30604241
Prasad M, Vora T, Agarwala S, Laskar S, Arora B, Bansal D, Kapoor G, Chinnaswamy G, Radhakrishnan V, Kaur T, Rath GK, Bakhshi S
Indian J Pediatr 2017 Jun;84(6):437-445. Epub 2017 Apr 3 doi: 10.1007/s12098-017-2305-5. PMID: 28367612

Recent clinical studies

Etiology

Spreafico F, Fernandez CV, Brok J, Nakata K, Vujanic G, Geller JI, Gessler M, Maschietto M, Behjati S, Polanco A, Paintsil V, Luna-Fineman S, Pritchard-Jones K
Nat Rev Dis Primers 2021 Oct 14;7(1):75. doi: 10.1038/s41572-021-00308-8. PMID: 34650095
Maciaszek JL, Oak N, Nichols KE
Hum Mol Genet 2020 Oct 20;29(R2):R138-R149. doi: 10.1093/hmg/ddaa091. PMID: 32412586
Servaes SE, Hoffer FA, Smith EA, Khanna G
Pediatr Radiol 2019 Oct;49(11):1441-1452. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04423-3. PMID: 31620845
Treger TD, Chowdhury T, Pritchard-Jones K, Behjati S
Nat Rev Nephrol 2019 Apr;15(4):240-251. doi: 10.1038/s41581-019-0112-0. PMID: 30705419
Green DM, D'Angio GJ, Beckwith JB, Breslow NE, Grundy PE, Ritchey ML, Thomas PR
CA Cancer J Clin 1996 Jan-Feb;46(1):46-63. doi: 10.3322/canjclin.46.1.46. PMID: 8548525

Diagnosis

Spreafico F, Fernandez CV, Brok J, Nakata K, Vujanic G, Geller JI, Gessler M, Maschietto M, Behjati S, Polanco A, Paintsil V, Luna-Fineman S, Pritchard-Jones K
Nat Rev Dis Primers 2021 Oct 14;7(1):75. doi: 10.1038/s41572-021-00308-8. PMID: 34650095
Maciaszek JL, Oak N, Nichols KE
Hum Mol Genet 2020 Oct 20;29(R2):R138-R149. doi: 10.1093/hmg/ddaa091. PMID: 32412586
Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, Ammerlaan C, van Ineveld RL, Derakhshan S, de Haan S, Dolman E, Lijnzaad P, Custers L, Begthel H, Kerstens HHD, Visser LL, Rookmaaker M, Verhaar M, Tytgat GAM, Kemmeren P, de Krijger RR, Al-Saadi R, Pritchard-Jones K, Kool M, Rios AC, van den Heuvel-Eibrink MM, Molenaar JJ, van Boxtel R, Holstege FCP, Clevers H, Drost J
Nat Commun 2020 Mar 11;11(1):1310. doi: 10.1038/s41467-020-15155-6. PMID: 32161258Free PMC Article
Servaes SE, Hoffer FA, Smith EA, Khanna G
Pediatr Radiol 2019 Oct;49(11):1441-1452. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04423-3. PMID: 31620845
Chen RY, Chang H
Arch Pathol Lab Med 2015 Apr;139(4):547-51. doi: 10.5858/arpa.2013-0660-RS. PMID: 25822765

Therapy

Kendsersky NM, Lindsay J, Kolb EA, Smith MA, Teicher BA, Erickson SW, Earley EJ, Mosse YP, Martinez D, Pogoriler J, Krytska K, Patel K, Groff D, Tsang M, Ghilu S, Wang Y, Seaman S, Feng Y, Croix BS, Gorlick R, Kurmasheva R, Houghton PJ, Maris JM
Clin Cancer Res 2021 May 15;27(10):2938-2946. Epub 2021 Feb 22 doi: 10.1158/1078-0432.CCR-20-4221. PMID: 33619171Free PMC Article
Weiser DA, West-Szymanski DC, Fraint E, Weiner S, Rivas MA, Zhao CWT, He C, Applebaum MA
Cancer Metastasis Rev 2019 Dec;38(4):553-571. doi: 10.1007/s10555-019-09825-1. PMID: 31836951Free PMC Article
Oostveen RM, Pritchard-Jones K
Paediatr Drugs 2019 Feb;21(1):1-13. doi: 10.1007/s40272-018-0323-z. PMID: 30604241
Millar AJ, Cox S, Davidson A
Pediatr Surg Int 2017 Apr;33(4):461-469. Epub 2017 Jan 4 doi: 10.1007/s00383-016-4047-2. PMID: 28054101
Libshitz HI, Cohen MA
Radiology 1982 Mar;142(3):643-7. doi: 10.1148/radiology.142.3.6278535. PMID: 6278535

Prognosis

Venkataramany AS, Schieffer KM, Lee K, Cottrell CE, Wang PY, Mardis ER, Cripe TP, Chandler DS
Ann Oncol 2022 Jun;33(6):578-592. Epub 2022 Mar 23 doi: 10.1016/j.annonc.2022.03.011. PMID: 35339647
Spreafico F, Fernandez CV, Brok J, Nakata K, Vujanic G, Geller JI, Gessler M, Maschietto M, Behjati S, Polanco A, Paintsil V, Luna-Fineman S, Pritchard-Jones K
Nat Rev Dis Primers 2021 Oct 14;7(1):75. doi: 10.1038/s41572-021-00308-8. PMID: 34650095
Parsons LN
Surg Pathol Clin 2020 Dec;13(4):683-693. doi: 10.1016/j.path.2020.08.007. PMID: 33183727
Ottaviani G, Jaffe N
Cancer Treat Res 2009;152:3-13. doi: 10.1007/978-1-4419-0284-9_1. PMID: 20213383
Green DM, D'Angio GJ, Beckwith JB, Breslow NE, Grundy PE, Ritchey ML, Thomas PR
CA Cancer J Clin 1996 Jan-Feb;46(1):46-63. doi: 10.3322/canjclin.46.1.46. PMID: 8548525

Clinical prediction guides

Foster KL, Salehabadi SM, Green DM, Xing M, Ness KK, Krull KR, Brinkman TM, Ehrhardt MJ, Chemaitilly W, Dixon SB, Bhakta N, Brennan RC, Krasin MJ, Davidoff AM, Robison LL, Hudson MM, Mulrooney DA
Pediatrics 2022 Nov 1;150(5) doi: 10.1542/peds.2022-056918. PMID: 36300342Free PMC Article
Venkataramany AS, Schieffer KM, Lee K, Cottrell CE, Wang PY, Mardis ER, Cripe TP, Chandler DS
Ann Oncol 2022 Jun;33(6):578-592. Epub 2022 Mar 23 doi: 10.1016/j.annonc.2022.03.011. PMID: 35339647
Iwańczyk K, Czachowski B, Sosnowska-Sienkiewicz P, Telman G, Ciążyńska P, Mańkowski P, Januszkiewicz-Lewandowska D
Genes (Basel) 2022 Feb 18;13(2) doi: 10.3390/genes13020372. PMID: 35205416Free PMC Article
Kendsersky NM, Lindsay J, Kolb EA, Smith MA, Teicher BA, Erickson SW, Earley EJ, Mosse YP, Martinez D, Pogoriler J, Krytska K, Patel K, Groff D, Tsang M, Ghilu S, Wang Y, Seaman S, Feng Y, Croix BS, Gorlick R, Kurmasheva R, Houghton PJ, Maris JM
Clin Cancer Res 2021 May 15;27(10):2938-2946. Epub 2021 Feb 22 doi: 10.1158/1078-0432.CCR-20-4221. PMID: 33619171Free PMC Article
Huff V
Am J Med Genet 1998 Oct 2;79(4):260-7. doi: 10.1002/(sici)1096-8628(19981002)79:4<260::aid-ajmg6>3.0.co;2-q. PMID: 9781905

Recent systematic reviews

Doganis D, Katsimpris A, Panagopoulou P, Bouka P, Bouka E, Moschovi M, Polychronopoulou S, Papakonstantinou E, Tragiannidis A, Katzilakis N, Dana H, Antoniadi K, Stefanaki K, Strantzia K, Dessypris N, Schüz J, Petridou ET
Cancer Epidemiol 2020 Aug;67:101769. Epub 2020 Jul 10 doi: 10.1016/j.canep.2020.101769. PMID: 32659726
Han Q, Li K, Dong K, Xiao X, Yao W, Liu G
J Pediatr Surg 2018 Dec;53(12):2465-2469. Epub 2018 Sep 1 doi: 10.1016/j.jpedsurg.2018.08.022. PMID: 30274708
Cone EB, Dalton SS, Van Noord M, Tracy ET, Rice HE, Routh JC
J Urol 2016 Nov;196(5):1530-1535. Epub 2016 May 31 doi: 10.1016/j.juro.2016.05.100. PMID: 27259655Free PMC Article
van Dalen EC, Raphaël MF, Caron HN, Kremer LC
Cochrane Database Syst Rev 2011 Jan 19;(1):CD006647. doi: 10.1002/14651858.CD006647.pub3. PMID: 21249679
Narchi H
Arch Dis Child 2005 Feb;90(2):147-9. doi: 10.1136/adc.2004.051243. PMID: 15665166Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...