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Childhood kidney neoplasm

MedGen UID:
232356
•Concept ID:
C1333003
•
Neoplastic Process
Synonyms: Childhood Kidney Neoplasm; childhood kidney neoplasm; Childhood Kidney Tumor; childhood kidney tumor; childhood kidney tumour; Childhood Renal Neoplasm; childhood renal neoplasm; Childhood Renal Tumor; childhood renal tumor; childhood renal tumour; kidney neoplasm of childhood; paediatric kidney neoplasm; paediatric kidney tumour; paediatric renal neoplasm; paediatric renal tumour; Pediatric Kidney Neoplasm; pediatric kidney neoplasm; Pediatric Kidney Tumor; pediatric kidney tumor; Pediatric Renal Neoplasm; pediatric renal neoplasm; Pediatric Renal Tumor; pediatric renal tumor
 
Monarch Initiative: MONDO:0002730

Definition

A kidney neoplasm that occurs in children. [from NCI]

Professional guidelines

PubMed

New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia.
Trpkov K, Hes O, Williamson SR, Adeniran AJ, Agaimy A, Alaghehbandan R, Amin MB, Argani P, Chen YB, Cheng L, Epstein JI, Cheville JC, Comperat E, da Cunha IW, Gordetsky JB, Gupta S, He H, Hirsch MS, Humphrey PA, Kapur P, Kojima F, Lopez JI, Maclean F, Magi-Galluzzi C, McKenney JK, Mehra R, Menon S, Netto GJ, Przybycin CG, Rao P, Rao Q, Reuter VE, Saleeb RM, Shah RB, Smith SC, Tickoo S, Tretiakova MS, True L, Verkarre V, Wobker SE, Zhou M, Gill AJ
Mod Pathol 2021 Jul;34(7):1392-1424. Epub 2021 Mar 4 doi: 10.1038/s41379-021-00779-w. PMID: 33664427
Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance.
Ramsey LB, Balis FM, O'Brien MM, Schmiegelow K, Pauley JL, Bleyer A, Widemann BC, Askenazi D, Bergeron S, Shirali A, Schwartz S, Vinks AA, Heldrup J
Oncologist 2018 Jan;23(1):52-61. Epub 2017 Oct 27 doi: 10.1634/theoncologist.2017-0243. PMID: 29079637Free PMC Article
Management of bilateral Wilms tumours.
Millar AJW, Cox S, Davidson A
Pediatr Surg Int 2017 Jul;33(7):737-745. Epub 2017 May 17 doi: 10.1007/s00383-017-4091-6. PMID: 28516188

Recent clinical studies

Etiology

Retinoic acid pathway activity in Wilms tumors and characterization of biological responses in vitro.
Wegert J, Bausenwein S, Kneitz S, Roth S, Graf N, Geissinger E, Gessler M
Mol Cancer 2011 Nov 8;10:136. doi: 10.1186/1476-4598-10-136. PMID: 22067876Free PMC Article

Prognosis

Wilms' tumor gene (WT1) competes with differentiation-inducing signal in hematopoietic progenitor cells.
Inoue K, Tamaki H, Ogawa H, Oka Y, Soma T, Tatekawa T, Oji Y, Tsuboi A, Kim EH, Kawakami M, Akiyama T, Kishimoto T, Sugiyama H
Blood 1998 Apr 15;91(8):2969-76. PMID: 9531608

Supplemental Content

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