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Colon small cell neuroendocrine carcinoma

MedGen UID:
232087
•Concept ID:
C1333099
•
Neoplastic Process
Synonyms: colon Oat cell carcinoma; Colon Small Cell Carcinoma; colon small cell carcinoma; colon small cell neuroendocrine cancer; Colon Small Cell Neuroendocrine Carcinoma; colon small cell neuroendocrine carcinoma; colonic Oat cell carcinoma; Colonic Small Cell Carcinoma; colonic small cell carcinoma; Oat cell carcinoma of colon; Oat cell carcinoma of the colon; Oat cell colon carcinoma; Small Cell Carcinoma of Colon; small cell carcinoma of colon; Small Cell Carcinoma of the Colon; small cell carcinoma of the colon; Small Cell Colon Carcinoma; small cell colon carcinoma
 
Monarch Initiative: MONDO:0003978

Definition

An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the colon. It is characterized by the presence of malignant small cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColon small cell neuroendocrine carcinoma

Professional guidelines

PubMed

PD-1/ PD-L1 blockade as a novel treatment for colorectal cancer.
Yaghoubi N, Soltani A, Ghazvini K, Hassanian SM, Hashemy SI
Biomed Pharmacother 2019 Feb;110:312-318. Epub 2018 Dec 3 doi: 10.1016/j.biopha.2018.11.105. PMID: 30522017
Immunotherapy in Non-Small Cell Lung Cancer Treatment: Current Status and the Role of Imaging.
Carter BW, Halpenny DF, Ginsberg MS, Papadimitrakopoulou VA, de Groot PM
J Thorac Imaging 2017 Sep;32(5):300-312. doi: 10.1097/RTI.0000000000000291. PMID: 28786858
Guidelines for the management of iron deficiency anaemia.
Goddard AF, James MW, McIntyre AS, Scott BB; British Society of Gastroenterology
Gut 2011 Oct;60(10):1309-16. Epub 2011 May 11 doi: 10.1136/gut.2010.228874. PMID: 21561874

Recent clinical studies

Etiology

Appendiceal cancer : a review of the literature.
Van de Moortele M, De Hertogh G, Sagaert X, Van Cutsem E
Acta Gastroenterol Belg 2020 Jul-Sep;83(3):441-448. PMID: 33094592
Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Psoriasis and cancer. An Australian/New Zealand narrative.
Rademaker M, Rubel DM, Agnew K, Andrews M, Armour KS, Baker C, Foley P, Gebauer K, Goh MS, Gupta M, Marshman G, Prince HM, Sullivan J
Australas J Dermatol 2019 Feb;60(1):12-18. Epub 2018 Jul 10 doi: 10.1111/ajd.12889. PMID: 29992535
Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label, phase 3 trial.
Wu YL, Cheng Y, Zhou X, Lee KH, Nakagawa K, Niho S, Tsuji F, Linke R, Rosell R, Corral J, Migliorino MR, Pluzanski A, Sbar EI, Wang T, White JL, Nadanaciva S, Sandin R, Mok TS
Lancet Oncol 2017 Nov;18(11):1454-1466. Epub 2017 Sep 25 doi: 10.1016/S1470-2045(17)30608-3. PMID: 28958502
miRNA and cancer; computational and experimental approaches.
Tutar Y
Curr Pharm Biotechnol 2014;15(5):429. doi: 10.2174/138920101505140828161335. PMID: 25189575

Diagnosis

Survival benefits of primary tumor surgery for synchronous brain metastases: A SEER-based population study with propensity-matched comparative analysis.
Zhang C, Zhang Y, Li D, Jia W
Cancer Med 2023 Feb;12(3):2677-2690. Epub 2022 Aug 14 doi: 10.1002/cam4.5142. PMID: 35965407Free PMC Article
Appendiceal cancer : a review of the literature.
Van de Moortele M, De Hertogh G, Sagaert X, Van Cutsem E
Acta Gastroenterol Belg 2020 Jul-Sep;83(3):441-448. PMID: 33094592
SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth.
Lu C, Klement JD, Yang D, Albers T, Lebedyeva IO, Waller JL, Liu K
Cancer Lett 2020 Apr 28;476:87-96. Epub 2020 Feb 12 doi: 10.1016/j.canlet.2020.02.004. PMID: 32061753Free PMC Article
miRNA and cancer; computational and experimental approaches.
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Curr Pharm Biotechnol 2014;15(5):429. doi: 10.2174/138920101505140828161335. PMID: 25189575
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Thomas RM, Sobin LH
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Therapy

Properties of FDA-approved small molecule protein kinase inhibitors: A 2022 update.
Roskoski R Jr
Pharmacol Res 2022 Jan;175:106037. Epub 2021 Dec 15 doi: 10.1016/j.phrs.2021.106037. PMID: 34921994
Appendiceal cancer : a review of the literature.
Van de Moortele M, De Hertogh G, Sagaert X, Van Cutsem E
Acta Gastroenterol Belg 2020 Jul-Sep;83(3):441-448. PMID: 33094592
Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Psoriasis and cancer. An Australian/New Zealand narrative.
Rademaker M, Rubel DM, Agnew K, Andrews M, Armour KS, Baker C, Foley P, Gebauer K, Goh MS, Gupta M, Marshman G, Prince HM, Sullivan J
Australas J Dermatol 2019 Feb;60(1):12-18. Epub 2018 Jul 10 doi: 10.1111/ajd.12889. PMID: 29992535
Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label, phase 3 trial.
Wu YL, Cheng Y, Zhou X, Lee KH, Nakagawa K, Niho S, Tsuji F, Linke R, Rosell R, Corral J, Migliorino MR, Pluzanski A, Sbar EI, Wang T, White JL, Nadanaciva S, Sandin R, Mok TS
Lancet Oncol 2017 Nov;18(11):1454-1466. Epub 2017 Sep 25 doi: 10.1016/S1470-2045(17)30608-3. PMID: 28958502

Prognosis

MIR4435-2HG Is a Potential Pan-Cancer Biomarker for Diagnosis and Prognosis.
Zhong C, Xie Z, Zeng LH, Yuan C, Duan S
Front Immunol 2022;13:855078. Epub 2022 Jun 15 doi: 10.3389/fimmu.2022.855078. PMID: 35784328Free PMC Article
Appendiceal cancer : a review of the literature.
Van de Moortele M, De Hertogh G, Sagaert X, Van Cutsem E
Acta Gastroenterol Belg 2020 Jul-Sep;83(3):441-448. PMID: 33094592
Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label, phase 3 trial.
Wu YL, Cheng Y, Zhou X, Lee KH, Nakagawa K, Niho S, Tsuji F, Linke R, Rosell R, Corral J, Migliorino MR, Pluzanski A, Sbar EI, Wang T, White JL, Nadanaciva S, Sandin R, Mok TS
Lancet Oncol 2017 Nov;18(11):1454-1466. Epub 2017 Sep 25 doi: 10.1016/S1470-2045(17)30608-3. PMID: 28958502
miRNA and cancer; computational and experimental approaches.
Tutar Y
Curr Pharm Biotechnol 2014;15(5):429. doi: 10.2174/138920101505140828161335. PMID: 25189575

Clinical prediction guides

Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies.
Oster P, Vaillant L, Riva E, McMillan B, Begka C, Truntzer C, Richard C, Leblond MM, Messaoudene M, Machremi E, Limagne E, Ghiringhelli F, Routy B, Verdeil G, Velin D
Gut 2022 Mar;71(3):457-466. Epub 2021 Jul 12 doi: 10.1136/gutjnl-2020-323392. PMID: 34253574Free PMC Article
Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
lncRNA CCAT1 promotes bladder cancer cell proliferation, migration and invasion.
Zhang C, Wang W, Lin J, Xiao J, Tian Y
Int Braz J Urol 2019 May-Jun;45(3):549-559. doi: 10.1590/S1677-5538.IBJU.2018.0450. PMID: 31038865Free PMC Article
Lenvatinib: A Promising Molecular Targeted Agent for Multiple Cancers.
Suyama K, Iwase H
Cancer Control 2018 Jan-Dec;25(1):1073274818789361. doi: 10.1177/1073274818789361. PMID: 30032643Free PMC Article
miRNA and cancer; computational and experimental approaches.
Tutar Y
Curr Pharm Biotechnol 2014;15(5):429. doi: 10.2174/138920101505140828161335. PMID: 25189575

Recent systematic reviews

Risk of Cancer in Inflammatory Bowel Diseases: Umbrella Review and Reanalysis of Meta-analyses.
Piovani D, Hassan C, Repici A, Rimassa L, Carlo-Stella C, Nikolopoulos GK, Riboli E, Bonovas S
Gastroenterology 2022 Sep;163(3):671-684. Epub 2022 May 26 doi: 10.1053/j.gastro.2022.05.038. PMID: 35643170
Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.
Zhang Q, Wang Q, Sun W, Gao F, Liu L, Cheng L, Li Z
Biomed Res Int 2018;2018:6124927. Epub 2018 Nov 25 doi: 10.1155/2018/6124927. PMID: 30596096Free PMC Article
Bevacizumab and wound-healing complications: a systematic review and meta-analysis of randomized controlled trials.
Zhang H, Huang Z, Zou X, Liu T
Oncotarget 2016 Dec 13;7(50):82473-82481. doi: 10.18632/oncotarget.12666. PMID: 27756883Free PMC Article
Possible association between hepatitis C virus and malignancies different from hepatocellular carcinoma: A systematic review.
Fiorino S, Bacchi-Reggiani L, de Biase D, Fornelli A, Masetti M, Tura A, Grizzi F, Zanello M, Mastrangelo L, Lombardi R, Acquaviva G, di Tommaso L, Bondi A, Visani M, Sabbatani S, Pontoriero L, Fabbri C, Cuppini A, Pession A, Jovine E
World J Gastroenterol 2015 Dec 7;21(45):12896-953. doi: 10.3748/wjg.v21.i45.12896. PMID: 26668515Free PMC Article
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer.
Linardou H, Dahabreh IJ, Kanaloupiti D, Siannis F, Bafaloukos D, Kosmidis P, Papadimitriou CA, Murray S
Lancet Oncol 2008 Oct;9(10):962-72. Epub 2008 Sep 17 doi: 10.1016/S1470-2045(08)70206-7. PMID: 18804418

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