U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Childhood pilocytic astrocytoma

MedGen UID:
232355
•Concept ID:
C1332995
•
Neoplastic Process
Synonyms: Childhood Pilocytic Astrocytoma; childhood pilocytic astrocytoma; paediatric pilocytic astrocytoma; Pediatric Pilocytic Astrocytoma; pediatric pilocytic astrocytoma; Pilocytic Astrocytoma of Childhood; pilocytic astrocytoma of childhood
 
Monarch Initiative: MONDO:0004000

Definition

A pilocytic astrocytoma that occurs during childhood. [from NCI]

Professional guidelines

PubMed

The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen.
Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed W, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, Cazacu S, deCarvalho AC, Khasraw M, Kocakavuk E, Kouwenhoven MCM, Migliozzi S, Niclou SP, Niers JM, Ormond DR, Paek SH, Reifenberger G, Sillevis Smitt PA, Smits M, Stead LF, van den Bent MJ, Van Meir EG, Walenkamp A, Weiss T, Weller M, Westerman BA, Ylstra B, Wesseling P, Lasorella A, French PJ, Poisson LM; Consortium The GLASS, Verhaak RGW, Iavarone A, Noushmehr H
Cancer Res 2024 Mar 4;84(5):741-756. doi: 10.1158/0008-5472.CAN-23-2093. PMID: 38117484Free PMC Article
Clinical Features, Treatment and Outcome of Childhood Glial Tumors.
Kara B, Ertan K, Karabagli P, Karabagli H, Yavas G, Caglayan AO, Koksal Y
Turk Neurosurg 2022;32(1):135-142. doi: 10.5137/1019-5149.JTN.34801-21.2. PMID: 34751424
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article

Recent clinical studies

Diagnosis

Diagnostic challenges of primary thalamic gliomas-identification of a minimally enhancing neuroradiological subtype with aggressive neuropathology and poor clinical outcome.
Kurian KM, Zhang Y, Haynes HR, Macaskill NA, Bradley M
Clin Neuroradiol 2014 Sep;24(3):231-8. Epub 2013 May 25 doi: 10.1007/s00062-013-0225-y. PMID: 23708758
Successful treatment of childhood pilocytic astrocytomas metastatic to the leptomeninges with high-dose cyclophosphamide.
McCowage G, Tien R, McLendon R, Felsberg G, Fuchs H, Graham ML, Kurtzberg J, Moghrabi A, Ferrell L, Kerby T, Duncan-Brown M, Stewart E, Robertson PL, Colvin OM, Golembe B, Bigner DD, Friedman HS
Med Pediatr Oncol 1996 Jul;27(1):32-9. doi: 10.1002/(SICI)1096-911X(199607)27:1<32::AID-MPO7>3.0.CO;2-V. PMID: 8614389

Therapy

Differences in vasculature between pilocytic and anaplastic astrocytomas of childhood.
Gesundheit B, Klement G, Senger C, Kerbel R, Kieran M, Baruchel S, Becker L
Med Pediatr Oncol 2003 Dec;41(6):516-26. doi: 10.1002/mpo.10308. PMID: 14595708
Successful treatment of childhood pilocytic astrocytomas metastatic to the leptomeninges with high-dose cyclophosphamide.
McCowage G, Tien R, McLendon R, Felsberg G, Fuchs H, Graham ML, Kurtzberg J, Moghrabi A, Ferrell L, Kerby T, Duncan-Brown M, Stewart E, Robertson PL, Colvin OM, Golembe B, Bigner DD, Friedman HS
Med Pediatr Oncol 1996 Jul;27(1):32-9. doi: 10.1002/(SICI)1096-911X(199607)27:1<32::AID-MPO7>3.0.CO;2-V. PMID: 8614389

Prognosis

Midbrain Gliofibroma Presenting in Adulthood following "Cure" of a Childhood Intraventricular Pilocytic Astrocytoma.
Ahmad MU, Barborie A, Pizer B, Husband D, Mallucci C, Jenkinson MD
Pediatr Neurosurg 2017;52(3):151-154. Epub 2017 Mar 1 doi: 10.1159/000455920. PMID: 28245445
Diagnostic challenges of primary thalamic gliomas-identification of a minimally enhancing neuroradiological subtype with aggressive neuropathology and poor clinical outcome.
Kurian KM, Zhang Y, Haynes HR, Macaskill NA, Bradley M
Clin Neuroradiol 2014 Sep;24(3):231-8. Epub 2013 May 25 doi: 10.1007/s00062-013-0225-y. PMID: 23708758
Differences in vasculature between pilocytic and anaplastic astrocytomas of childhood.
Gesundheit B, Klement G, Senger C, Kerbel R, Kieran M, Baruchel S, Becker L
Med Pediatr Oncol 2003 Dec;41(6):516-26. doi: 10.1002/mpo.10308. PMID: 14595708

Clinical prediction guides

mRNA and miRNA Expression Analyses of the MYC/E2F/miR-17-92 Network in the Most Common Pediatric Brain Tumors.
Gruszka R, Zakrzewski K, Liberski PP, Zakrzewska M
Int J Mol Sci 2021 Jan 7;22(2) doi: 10.3390/ijms22020543. PMID: 33430425Free PMC Article
Diagnostic challenges of primary thalamic gliomas-identification of a minimally enhancing neuroradiological subtype with aggressive neuropathology and poor clinical outcome.
Kurian KM, Zhang Y, Haynes HR, Macaskill NA, Bradley M
Clin Neuroradiol 2014 Sep;24(3):231-8. Epub 2013 May 25 doi: 10.1007/s00062-013-0225-y. PMID: 23708758
Differences in vasculature between pilocytic and anaplastic astrocytomas of childhood.
Gesundheit B, Klement G, Senger C, Kerbel R, Kieran M, Baruchel S, Becker L
Med Pediatr Oncol 2003 Dec;41(6):516-26. doi: 10.1002/mpo.10308. PMID: 14595708

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...