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Iris spindle cell melanoma

MedGen UID:
232672
Concept ID:
C1334287
Neoplastic Process
Synonyms: Iris Spindle Cell Melanoma; iris spindle cell melanoma; Spindle Cell Melanoma of Iris; spindle cell melanoma of iris; Spindle Cell Melanoma of the Iris; spindle cell melanoma of the iris
 
Monarch Initiative: MONDO:0004188

Definition

A melanoma that arises from the iris. It is characterized by the presence of spindle-shaped melanocytes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIris spindle cell melanoma

Professional guidelines

PubMed

Krishna Y, Kalirai H, Thornton S, Damato BE, Heimann H, Coupland SE
Br J Ophthalmol 2016 Jul;100(7):1012-1016. Epub 2016 Apr 20 doi: 10.1136/bjophthalmol-2015-308301. PMID: 27098748
Conway RM, Chua WC, Qureshi C, Billson FA
Br J Ophthalmol 2001 Jul;85(7):848-54. doi: 10.1136/bjo.85.7.848. PMID: 11423461Free PMC Article
Noor Sunba MS, Rahi AH, Garner A, Alexander RA, Morgan G
Br J Ophthalmol 1980 Nov;64(11):867-74. doi: 10.1136/bjo.64.11.867. PMID: 7426559Free PMC Article

Recent clinical studies

Etiology

Sabazade S, Herrspiegel C, Gill V, Stålhammar G
BMC Cancer 2021 Nov 24;21(1):1270. doi: 10.1186/s12885-021-09002-0. PMID: 34819035Free PMC Article
Khan S, Finger PT, Yu GP, Razzaq L, Jager MJ, de Keizer RJ, Sandkull P, Seregard S, Gologorsky D, Schefler AC, Murray TG, Kivelä T, Giuliari GP, McGowan H, Simpson ER, Corriveau C, Coupland SE, Damato BE
Arch Ophthalmol 2012 Jan;130(1):57-64. Epub 2011 Sep 12 doi: 10.1001/archophthalmol.2011.286. PMID: 21911649
Henderson E, Margo CE
Arch Pathol Lab Med 2008 Feb;132(2):268-72. doi: 10.5858/2008-132-268-IM. PMID: 18251588
Demirci H, Shields CL, Shields JA, Eagle RC Jr, Honavar SG
Ophthalmology 2002 Aug;109(8):1553-60. doi: 10.1016/s0161-6420(02)01104-1. PMID: 12153810
Geisse LJ, Robertson DM
Am J Ophthalmol 1985 Jun 15;99(6):638-48. doi: 10.1016/s0002-9394(14)76028-3. PMID: 4014387

Diagnosis

Sabazade S, Herrspiegel C, Gill V, Stålhammar G
BMC Cancer 2021 Nov 24;21(1):1270. doi: 10.1186/s12885-021-09002-0. PMID: 34819035Free PMC Article
Gokhale R, Medina CA, Biscotti CV, Singh AD
Asia Pac J Ophthalmol (Phila) 2015 Mar-Apr;4(2):89-91. doi: 10.1097/APO.0000000000000083. PMID: 26065351
Henderson E, Margo CE
Arch Pathol Lab Med 2008 Feb;132(2):268-72. doi: 10.5858/2008-132-268-IM. PMID: 18251588
Demirci H, Shields CL, Shields JA, Eagle RC Jr, Honavar SG
Ophthalmology 2002 Aug;109(8):1553-60. doi: 10.1016/s0161-6420(02)01104-1. PMID: 12153810
Geisse LJ, Robertson DM
Am J Ophthalmol 1985 Jun 15;99(6):638-48. doi: 10.1016/s0002-9394(14)76028-3. PMID: 4014387

Therapy

Sabazade S, Herrspiegel C, Gill V, Stålhammar G
BMC Cancer 2021 Nov 24;21(1):1270. doi: 10.1186/s12885-021-09002-0. PMID: 34819035Free PMC Article
Bergeron E, Lihimdi N, Bergeron D, Landreville S
BMJ Case Rep 2017 Sep 7;2017 doi: 10.1136/bcr-2017-221137. PMID: 28882848Free PMC Article
Harley MR, Rao R, Lally SE, Shields CL
J AAPOS 2017 Aug;21(4):340-342. Epub 2017 Jun 16 doi: 10.1016/j.jaapos.2017.06.007. PMID: 28630029
Grossniklaus HE, Brown RH, Stulting RD, Blasberg RD
Arch Ophthalmol 1990 Sep;108(9):1287-90. doi: 10.1001/archopht.1990.01070110103033. PMID: 2400348
Osterlind A
Int J Cancer 1987 Aug 15;40(2):161-4. doi: 10.1002/ijc.2910400206. PMID: 3610385

Prognosis

Sabazade S, Herrspiegel C, Gill V, Stålhammar G
BMC Cancer 2021 Nov 24;21(1):1270. doi: 10.1186/s12885-021-09002-0. PMID: 34819035Free PMC Article
Henderson E, Margo CE
Arch Pathol Lab Med 2008 Feb;132(2):268-72. doi: 10.5858/2008-132-268-IM. PMID: 18251588
McLean IW, Saraiva VS, Burnier MN Jr
Can J Ophthalmol 2004 Jun;39(4):343-50. doi: 10.1016/s0008-4182(04)80004-8. PMID: 15327098
Demirci H, Shields CL, Shields JA, Eagle RC Jr, Honavar SG
Ophthalmology 2002 Aug;109(8):1553-60. doi: 10.1016/s0161-6420(02)01104-1. PMID: 12153810
Geisse LJ, Robertson DM
Am J Ophthalmol 1985 Jun 15;99(6):638-48. doi: 10.1016/s0002-9394(14)76028-3. PMID: 4014387

Clinical prediction guides

Sabazade S, Herrspiegel C, Gill V, Stålhammar G
BMC Cancer 2021 Nov 24;21(1):1270. doi: 10.1186/s12885-021-09002-0. PMID: 34819035Free PMC Article
Medina CA, Biscotti CV, Singh N, Singh AD
Ophthalmology 2015 Aug;122(8):1580-4. Epub 2015 May 23 doi: 10.1016/j.ophtha.2015.04.013. PMID: 26012864
McLean IW, Saraiva VS, Burnier MN Jr
Can J Ophthalmol 2004 Jun;39(4):343-50. doi: 10.1016/s0008-4182(04)80004-8. PMID: 15327098
Demirci H, Shields CL, Shields JA, Eagle RC Jr, Honavar SG
Ophthalmology 2002 Aug;109(8):1553-60. doi: 10.1016/s0161-6420(02)01104-1. PMID: 12153810
Conway RM, Chua WC, Qureshi C, Billson FA
Br J Ophthalmol 2001 Jul;85(7):848-54. doi: 10.1136/bjo.85.7.848. PMID: 11423461Free PMC Article

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