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Stage IVC Pharyngeal Cancer

MedGen UID:
233531
•Concept ID:
C1336409
•
Neoplastic Process
Synonyms: Pharyngeal Cancer Stage IVC; Stage IVC Carcinoma of Pharynx; Stage IVC Carcinoma of the Pharynx; Stage IVC Pharyngeal Carcinoma; Stage IVC Pharynx Carcinoma

Definition

Stage IVC carcinoma of the pharynx according to the American Joint Committee on Cancer, 6th, 7th, and 8th editions. [from NCI]

Professional guidelines

PubMed

Individualized treatment in stage IVC nasopharyngeal carcinoma.
Chan OS, Ngan RK
Oral Oncol 2014 Sep;50(9):791-7. Epub 2014 Feb 8 doi: 10.1016/j.oraloncology.2014.01.004. PMID: 24518920
Multimodality treatment for anaplastic thyroid carcinoma--treatment outcome in 75 patients.
Swaak-Kragten AT, de Wilt JH, Schmitz PI, Bontenbal M, Levendag PC
Radiother Oncol 2009 Jul;92(1):100-4. Epub 2009 Mar 26 doi: 10.1016/j.radonc.2009.02.016. PMID: 19328572
Treatment outcomes of patients with AJCC stage IVC nasopharyngeal carcinoma: benefits of primary radiotherapy.
Yeh SA, Tang Y, Lui CC, Huang EY
Jpn J Clin Oncol 2006 Mar;36(3):132-6. Epub 2006 Mar 6 doi: 10.1093/jjco/hyi245. PMID: 16520357

Recent clinical studies

Etiology

Comparison of the Seventh and Eighth Edition of American Joint Committee on Cancer (AJCC) Staging for Selected and Nonselected Oropharyngeal Squamous Cell Carcinomas.
Vijayvargiya P, Trivedi S, Rupji M, Song H, Liu Y, Jiang R, Kaka AS, Chen GZ, Stokes W, Steuer C, Shin DM, Beitler JJ, Patel MR, Aiken A, Saba NF
Oncologist 2022 Feb 3;27(1):48-56. doi: 10.1093/oncolo/oyab001. PMID: 35305095Free PMC Article
Electron microscopy of juvenile nasopharyngeal angiofibroma: clinical and histopathological correlates.
Hage A, Singhai A, Mishra A, Mishra SC
Eur Arch Otorhinolaryngol 2022 Jan;279(1):233-247. Epub 2021 Apr 29 doi: 10.1007/s00405-021-06815-4. PMID: 33912996
Prognostic model and optimal treatment for patients with stage IVc nasopharyngeal carcinoma at diagnosis.
Tian YM, Huang WZ, Lan YH, Zhao C, Bai L, Han F
Sci Rep 2019 Dec 17;9(1):19272. doi: 10.1038/s41598-019-55586-w. PMID: 31848409Free PMC Article
Carotid artery infusion via implantable catheters for squamous cell carcinoma of the tonsils.
Aigner KR, Gailhofer S, Aigner K
World J Surg Oncol 2018 Jun 5;16(1):104. doi: 10.1186/s12957-018-1404-8. PMID: 29871686Free PMC Article
Individualized treatment in stage IVC nasopharyngeal carcinoma.
Chan OS, Ngan RK
Oral Oncol 2014 Sep;50(9):791-7. Epub 2014 Feb 8 doi: 10.1016/j.oraloncology.2014.01.004. PMID: 24518920

Diagnosis

Patterns of Care and Outcome Analysis of Nasopharyngeal Carcinoma: An Indonesian Single Institution Study.
Faisal HH, Kubo N, Nuryadi E, Prihartono J, Atmakusuma TD, Rachmadi L, Oike T, Nakano T, Gondhowiardjo SA, Adham M
Asian Pac J Cancer Prev 2020 May 1;21(5):1481-1485. doi: 10.31557/APJCP.2020.21.5.1481. PMID: 32458659Free PMC Article
Prognostic model and optimal treatment for patients with stage IVc nasopharyngeal carcinoma at diagnosis.
Tian YM, Huang WZ, Lan YH, Zhao C, Bai L, Han F
Sci Rep 2019 Dec 17;9(1):19272. doi: 10.1038/s41598-019-55586-w. PMID: 31848409Free PMC Article
Societal cost of oropharyngeal cancer by human papillomavirus status, cancer stage, and subsite.
Silfverschiöld M, Sjövall J, Wennerberg J, Östensson E, Greiff L
PLoS One 2019;14(7):e0220534. Epub 2019 Jul 29 doi: 10.1371/journal.pone.0220534. PMID: 31356646Free PMC Article
Cost-effectiveness of Screening for Nasopharyngeal Carcinoma among Asian American Men in the United States.
Harris JP, Saraswathula A, Kaplun B, Qian Y, Chan KCA, Chan ATC, Le QT, Owens DK, Goldhaber-Fiebert JD, Pollom E
Otolaryngol Head Neck Surg 2019 Jul;161(1):82-90. Epub 2019 Mar 5 doi: 10.1177/0194599819832593. PMID: 30832545
Long-Term Outcomes of Nasopharyngeal Carcinoma in 148 Children and Adolescents.
Lu S, Chang H, Sun X, Zhen Z, Sun F, Zhu J, Wang J, Huang J, Liao R, Guo X, Lu L, Gao Y
Medicine (Baltimore) 2016 Apr;95(17):e3445. doi: 10.1097/MD.0000000000003445. PMID: 27124036Free PMC Article

Therapy

Patterns of Care and Outcome Analysis of Nasopharyngeal Carcinoma: An Indonesian Single Institution Study.
Faisal HH, Kubo N, Nuryadi E, Prihartono J, Atmakusuma TD, Rachmadi L, Oike T, Nakano T, Gondhowiardjo SA, Adham M
Asian Pac J Cancer Prev 2020 May 1;21(5):1481-1485. doi: 10.31557/APJCP.2020.21.5.1481. PMID: 32458659Free PMC Article
Prognostic model and optimal treatment for patients with stage IVc nasopharyngeal carcinoma at diagnosis.
Tian YM, Huang WZ, Lan YH, Zhao C, Bai L, Han F
Sci Rep 2019 Dec 17;9(1):19272. doi: 10.1038/s41598-019-55586-w. PMID: 31848409Free PMC Article
Carotid artery infusion via implantable catheters for squamous cell carcinoma of the tonsils.
Aigner KR, Gailhofer S, Aigner K
World J Surg Oncol 2018 Jun 5;16(1):104. doi: 10.1186/s12957-018-1404-8. PMID: 29871686Free PMC Article
Individualized treatment in stage IVC nasopharyngeal carcinoma.
Chan OS, Ngan RK
Oral Oncol 2014 Sep;50(9):791-7. Epub 2014 Feb 8 doi: 10.1016/j.oraloncology.2014.01.004. PMID: 24518920
Aichi cancer center initial experience of intensity modulated radiation therapy for nasopharyngeal cancer using helical tomotherapy.
Kodaira T, Tomita N, Tachibana H, Nakamura T, Nakahara R, Inokuchi H, Fuwa N
Int J Radiat Oncol Biol Phys 2009 Mar 15;73(4):1129-34. Epub 2008 Oct 14 doi: 10.1016/j.ijrobp.2008.06.1936. PMID: 18922651

Prognosis

Comparison of the Seventh and Eighth Edition of American Joint Committee on Cancer (AJCC) Staging for Selected and Nonselected Oropharyngeal Squamous Cell Carcinomas.
Vijayvargiya P, Trivedi S, Rupji M, Song H, Liu Y, Jiang R, Kaka AS, Chen GZ, Stokes W, Steuer C, Shin DM, Beitler JJ, Patel MR, Aiken A, Saba NF
Oncologist 2022 Feb 3;27(1):48-56. doi: 10.1093/oncolo/oyab001. PMID: 35305095Free PMC Article
Electron microscopy of juvenile nasopharyngeal angiofibroma: clinical and histopathological correlates.
Hage A, Singhai A, Mishra A, Mishra SC
Eur Arch Otorhinolaryngol 2022 Jan;279(1):233-247. Epub 2021 Apr 29 doi: 10.1007/s00405-021-06815-4. PMID: 33912996
Prognostic model and optimal treatment for patients with stage IVc nasopharyngeal carcinoma at diagnosis.
Tian YM, Huang WZ, Lan YH, Zhao C, Bai L, Han F
Sci Rep 2019 Dec 17;9(1):19272. doi: 10.1038/s41598-019-55586-w. PMID: 31848409Free PMC Article
Societal cost of oropharyngeal cancer by human papillomavirus status, cancer stage, and subsite.
Silfverschiöld M, Sjövall J, Wennerberg J, Östensson E, Greiff L
PLoS One 2019;14(7):e0220534. Epub 2019 Jul 29 doi: 10.1371/journal.pone.0220534. PMID: 31356646Free PMC Article
Individualized treatment in stage IVC nasopharyngeal carcinoma.
Chan OS, Ngan RK
Oral Oncol 2014 Sep;50(9):791-7. Epub 2014 Feb 8 doi: 10.1016/j.oraloncology.2014.01.004. PMID: 24518920

Clinical prediction guides

Comparison of the Seventh and Eighth Edition of American Joint Committee on Cancer (AJCC) Staging for Selected and Nonselected Oropharyngeal Squamous Cell Carcinomas.
Vijayvargiya P, Trivedi S, Rupji M, Song H, Liu Y, Jiang R, Kaka AS, Chen GZ, Stokes W, Steuer C, Shin DM, Beitler JJ, Patel MR, Aiken A, Saba NF
Oncologist 2022 Feb 3;27(1):48-56. doi: 10.1093/oncolo/oyab001. PMID: 35305095Free PMC Article
Electron microscopy of juvenile nasopharyngeal angiofibroma: clinical and histopathological correlates.
Hage A, Singhai A, Mishra A, Mishra SC
Eur Arch Otorhinolaryngol 2022 Jan;279(1):233-247. Epub 2021 Apr 29 doi: 10.1007/s00405-021-06815-4. PMID: 33912996
Clinicopathological and prognostic features of nasopharyngeal carcinoma in children and adolescents: A retrospective study of 196 cases in South China.
Zhang J, Luo X, Huang Q, Huang Y
Int J Cancer 2021 Mar 1;148(5):1087-1096. Epub 2020 Sep 21 doi: 10.1002/ijc.33293. PMID: 32930415
Prognostic model and optimal treatment for patients with stage IVc nasopharyngeal carcinoma at diagnosis.
Tian YM, Huang WZ, Lan YH, Zhao C, Bai L, Han F
Sci Rep 2019 Dec 17;9(1):19272. doi: 10.1038/s41598-019-55586-w. PMID: 31848409Free PMC Article
Long-Term Outcomes of Nasopharyngeal Carcinoma in 148 Children and Adolescents.
Lu S, Chang H, Sun X, Zhen Z, Sun F, Zhu J, Wang J, Huang J, Liao R, Guo X, Lu L, Gao Y
Medicine (Baltimore) 2016 Apr;95(17):e3445. doi: 10.1097/MD.0000000000003445. PMID: 27124036Free PMC Article

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