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Low Grade Gastric Intraepithelial Neoplasia

MedGen UID:
233619
•Concept ID:
C1334415
•
Neoplastic Process
Synonyms: Gastric Mild Intraepithelial Neoplasia (Dysplasia); Low Grade Gastric Intraepithelial Neoplasia (Dysplasia); Low-Grade Gastric Glandular Intraepithelial Neoplasia

Definition

A gastric intraepithelial lesion characterized by the presence of neoplastic cells with mild cytologic atypia, mild architectural changes, and low number of mitotic figures. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLow Grade Gastric Intraepithelial Neoplasia

Professional guidelines

PubMed

Gastric cancer screening in low incidence populations: Position statement of AEG, SEED and SEAP.
Cubiella J, Pérez Aisa Á, Cuatrecasas M, Díez Redondo P, Fernández Esparrach G, Marín-Gabriel JC, Moreira L, Núñez H, Pardo López ML, Rodríguez de Santiago E, Rosón P, Sanz Anquela JM, Calvet X; en representación de la Asociación Española de Gastroenterología, la Sociedad Española de Endoscopia Digestiva y la Sociedad Española de Anatomía Patológica
Gastroenterol Hepatol 2021 Jan;44(1):67-86. Epub 2020 Oct 24 doi: 10.1016/j.gastrohep.2020.08.004. PMID: 33252332
Diagnosis and management of gastric dysplasia.
Sung JK
Korean J Intern Med 2016 Mar;31(2):201-9. Epub 2016 Feb 26 doi: 10.3904/kjim.2016.021. PMID: 26932397Free PMC Article
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article

Recent clinical studies

Clinical prediction guides

Methylation of GATA-4 and GATA-5 and development of sporadic gastric carcinomas.
Wen XZ, Akiyama Y, Pan KF, Liu ZJ, Lu ZM, Zhou J, Gu LK, Dong CX, Zhu BD, Ji JF, You WC, Deng DJ
World J Gastroenterol 2010 Mar 14;16(10):1201-8. doi: 10.3748/wjg.v16.i10.1201. PMID: 20222162Free PMC Article

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