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Ampulla of vater mucinous adenocarcinoma

MedGen UID:
233973
Concept ID:
C1332248
Neoplastic Process
Synonyms: Ampulla of Vater Mucinous Adenocarcinoma; ampulla of vater mucinous adenocarcinoma; ampulla of Vater mucinous adenocarcinoma; hepatopancreatic ampulla mucinous adenocarcinoma
 
Monarch Initiative: MONDO:0002736

Definition

A carcinoma with glandular differentiation arising from the ampulla of Vater. Morphologically, it is characterized by the presence of mucoid stroma formation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmpulla of vater mucinous adenocarcinoma

Recent clinical studies

Etiology

Vicentini C, Calore F, Nigita G, Fadda P, Simbolo M, Sperandio N, Luchini C, Lawlor RT, Croce CM, Corbo V, Fassan M, Scarpa A
BMC Gastroenterol 2020 May 6;20(1):137. doi: 10.1186/s12876-020-01287-y. PMID: 32375666Free PMC Article
Ang DC, Shia J, Tang LH, Katabi N, Klimstra DS
Am J Surg Pathol 2014 Oct;38(10):1371-9. doi: 10.1097/PAS.0000000000000230. PMID: 24832159
Kohler I, Jacob D, Budzies J, Lehmann A, Weichert W, Schulz S, Neuhaus P, Röcken C
Am J Clin Pathol 2011 Feb;135(2):202-11. doi: 10.1309/AJCPCTCUQSYI89YT. PMID: 21228360
Ruemmele P, Dietmaier W, Terracciano L, Tornillo L, Bataille F, Kaiser A, Wuensch PH, Heinmoeller E, Homayounfar K, Luettges J, Kloeppel G, Sessa F, Edmonston TB, Schneider-Stock R, Klinkhammer-Schalke M, Pauer A, Schick S, Hofstaedter F, Baumhoer D, Hartmann A
Am J Surg Pathol 2009 May;33(5):691-704. doi: 10.1097/PAS.0b013e3181983ef7. PMID: 19252434
Shyr YM, Su CH, Tsay SH, Lui WY
Ann Surg 1996 Feb;223(2):141-6. doi: 10.1097/00000658-199602000-00005. PMID: 8597507Free PMC Article

Diagnosis

Bakshi N, Dhawan S, Nundy S, Rao S, Chopra P, Bhalla S
Int J Surg Pathol 2019 Sep;27(6):598-608. Epub 2019 Apr 3 doi: 10.1177/1066896919837606. PMID: 30942099
Jang KT, Ahn S
Arch Pathol Lab Med 2016 May;140(5):429-36. doi: 10.5858/arpa.2015-0319-RA. PMID: 27128300
Ang DC, Shia J, Tang LH, Katabi N, Klimstra DS
Am J Surg Pathol 2014 Oct;38(10):1371-9. doi: 10.1097/PAS.0000000000000230. PMID: 24832159
Takada T, Yasuda H, Amano H, Yoshida M, Hijikata H, Takada K
Hepatogastroenterology 1998 Nov-Dec;45(24):1967-72. PMID: 9951849
Shyr YM, Su CH, Tsay SH, Lui WY
Ann Surg 1996 Feb;223(2):141-6. doi: 10.1097/00000658-199602000-00005. PMID: 8597507Free PMC Article

Therapy

Kitami CE, Kurosaki I, Koyama Y, Makino H, Hatakeyama K
J Hepatobiliary Pancreat Surg 2005;12(4):321-3. doi: 10.1007/s00534-005-0972-5. PMID: 16133701
Wagner M, Z'graggen K, Vagianos CE, Redaelli CA, Holzinger F, Sadowski C, Kulli C, Zimmermann H, Baer HU, Büchler MW
Dig Surg 2001;18(3):188-95. doi: 10.1159/000050128. PMID: 11464008

Prognosis

Vicentini C, Calore F, Nigita G, Fadda P, Simbolo M, Sperandio N, Luchini C, Lawlor RT, Croce CM, Corbo V, Fassan M, Scarpa A
BMC Gastroenterol 2020 May 6;20(1):137. doi: 10.1186/s12876-020-01287-y. PMID: 32375666Free PMC Article
Bakshi N, Dhawan S, Nundy S, Rao S, Chopra P, Bhalla S
Int J Surg Pathol 2019 Sep;27(6):598-608. Epub 2019 Apr 3 doi: 10.1177/1066896919837606. PMID: 30942099
Sahora K, Crippa S, Zamboni G, Ferrone C, Warshaw AL, Lillemoe K, Mino-Kenudson M, Falconi M, Fernandez-del Castillo C
Eur J Surg Oncol 2016 Feb;42(2):197-204. Epub 2015 Dec 1 doi: 10.1016/j.ejso.2015.10.014. PMID: 26687069
Ang DC, Shia J, Tang LH, Katabi N, Klimstra DS
Am J Surg Pathol 2014 Oct;38(10):1371-9. doi: 10.1097/PAS.0000000000000230. PMID: 24832159
Takada T, Yasuda H, Amano H, Yoshida M, Hijikata H, Takada K
Hepatogastroenterology 1998 Nov-Dec;45(24):1967-72. PMID: 9951849

Clinical prediction guides

Nanashima A, Imamura N, Nishida T, Hiyoshi M, Uchise Y, Hamada T, Yano K, Tsuchimochi Y
Clin J Gastroenterol 2022 Dec;15(6):1169-1172. Epub 2022 Oct 15 doi: 10.1007/s12328-022-01714-5. PMID: 36242750
Zhang TT, Sadler TJ, Whitley S, Brais R, Godfrey E
Br J Radiol 2019 Nov;92(1103):20190461. Epub 2019 Aug 28 doi: 10.1259/bjr.20190461. PMID: 31430199Free PMC Article
Rosenbaum MW, Cauley CE, Kulemann B, Liss AS, Castillo CF, Warshaw AL, Lillemoe KD, Thayer SP, Pitman MB
Cancer Cytopathol 2017 May;125(5):332-340. Epub 2017 Mar 3 doi: 10.1002/cncy.21841. PMID: 28257167Free PMC Article
Ang DC, Shia J, Tang LH, Katabi N, Klimstra DS
Am J Surg Pathol 2014 Oct;38(10):1371-9. doi: 10.1097/PAS.0000000000000230. PMID: 24832159
Ogawa H, Itoh S, Ikeda M, Suzuki K, Naganawa S
Radiology 2008 Sep;248(3):876-86. Epub 2008 Jul 15 doi: 10.1148/radiol.2482071578. PMID: 18632526

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