U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Common Variant Anaplastic Large Cell Lymphoma

MedGen UID:
234169
•Concept ID:
C1333133
•
Neoplastic Process

Definition

An anaplastic large cell lymphoma, characterized by CD30 positive lymphoid cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCommon Variant Anaplastic Large Cell Lymphoma

Professional guidelines

PubMed

Primary Cutaneous Lymphomas in Thailand: A 10-Year Retrospective Study.
Pruksaeakanan C, Teyateeti P, Patthamalai P, Thumrongtharadol J, Chairatchaneeboon M
Biomed Res Int 2021;2021:4057661. Epub 2021 Jun 11 doi: 10.1155/2021/4057661. PMID: 34235215Free PMC Article
Diagnosis and Management of Cutaneous Lymphomas Including Cutaneous T-cell Lymphoma.
Zic JA
Med Clin North Am 2021 Jul;105(4):737-755. doi: 10.1016/j.mcna.2021.04.010. PMID: 34059248
CD30+ lymphoproliferative disorders: histopathology, differential diagnosis, new variants, and simulators.
Kempf W
J Cutan Pathol 2006 Feb;33 Suppl 1:58-70. doi: 10.1111/j.0303-6987.2006.00548.x. PMID: 16412214

Recent clinical studies

Etiology

Primary cutaneous T-cell lymphoma: a review of the most common entities with focus on recent updates.
Saleh JS, Subtil A, Hristov AC
Hum Pathol 2023 Oct;140:75-100. Epub 2023 Oct 4 doi: 10.1016/j.humpath.2023.09.009. PMID: 37802757
Classification and diagnostic evaluation of nodal T- and NK-cell lymphomas.
Feldman AL, Laurent C, Narbaitz M, Nakamura S, Chan WC, de Leval L, Gaulard P
Virchows Arch 2023 Jan;482(1):265-279. Epub 2022 Oct 10 doi: 10.1007/s00428-022-03412-6. PMID: 36210383
Cutaneous lymphoma: Kids are not just little people.
Ferenczi K, Makkar HS
Clin Dermatol 2016 Nov-Dec;34(6):749-759. Epub 2016 Jul 10 doi: 10.1016/j.clindermatol.2016.07.010. PMID: 27968935
CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features.
Stein H, Foss HD, Dürkop H, Marafioti T, Delsol G, Pulford K, Pileri S, Falini B
Blood 2000 Dec 1;96(12):3681-95. PMID: 11090048
The pathologic and clinical spectrum of anaplastic large cell lymphoma and correlation with ALK gene dysregulation.
Kinney MC, Kadin ME
Am J Clin Pathol 1999 Jan;111(1 Suppl 1):S56-67. PMID: 9894470

Diagnosis

Primary cutaneous T-cell lymphoma: a review of the most common entities with focus on recent updates.
Saleh JS, Subtil A, Hristov AC
Hum Pathol 2023 Oct;140:75-100. Epub 2023 Oct 4 doi: 10.1016/j.humpath.2023.09.009. PMID: 37802757
Classification and diagnostic evaluation of nodal T- and NK-cell lymphomas.
Feldman AL, Laurent C, Narbaitz M, Nakamura S, Chan WC, de Leval L, Gaulard P
Virchows Arch 2023 Jan;482(1):265-279. Epub 2022 Oct 10 doi: 10.1007/s00428-022-03412-6. PMID: 36210383
Diagnosis and Management of Cutaneous Lymphomas Including Cutaneous T-cell Lymphoma.
Zic JA
Med Clin North Am 2021 Jul;105(4):737-755. doi: 10.1016/j.mcna.2021.04.010. PMID: 34059248
CD30-Positive Lymphoproliferative Disorders.
Nikolaenko L, Zain J, Rosen ST, Querfeld C
Cancer Treat Res 2019;176:249-268. doi: 10.1007/978-3-319-99716-2_12. PMID: 30596222
Cutaneous lymphoma: Kids are not just little people.
Ferenczi K, Makkar HS
Clin Dermatol 2016 Nov-Dec;34(6):749-759. Epub 2016 Jul 10 doi: 10.1016/j.clindermatol.2016.07.010. PMID: 27968935

Therapy

Diagnosis and Management of Cutaneous Lymphomas Including Cutaneous T-cell Lymphoma.
Zic JA
Med Clin North Am 2021 Jul;105(4):737-755. doi: 10.1016/j.mcna.2021.04.010. PMID: 34059248
Decreased MYC-associated factor X (MAX) expression is a new potential biomarker for adverse prognosis in anaplastic large cell lymphoma.
Yamashita T, Higashi M, Momose S, Adachi A, Watanabe T, Tanaka Y, Tokuhira M, Kizaki M, Tamaru JI
Sci Rep 2020 Jun 25;10(1):10391. doi: 10.1038/s41598-020-67500-w. PMID: 32587329Free PMC Article
Cutaneous lymphoproliferative disorders in organ transplant recipients: update 2014.
Seçkin D
G Ital Dermatol Venereol 2014 Aug;149(4):401-8. PMID: 25068227
Anaplastic lymphoma kinase-positive diffuse large B-cell lymphoma: a rare clinicopathologic entity with poor prognosis.
Laurent C, Do C, Gascoyne RD, Lamant L, Ysebaert L, Laurent G, Delsol G, Brousset P
J Clin Oncol 2009 Sep 1;27(25):4211-6. Epub 2009 Jul 27 doi: 10.1200/JCO.2008.21.5020. PMID: 19636007
Primary brain CD30+ ALK1+ anaplastic large cell lymphoma ('ALKoma'): the first case with a combination of 'not common' variants.
Ponzoni M, Terreni MR, Ciceri F, Ferreri AJ, Gerevini S, Anzalone N, Valle M, Pizzolito S, Arrigoni G
Ann Oncol 2002 Nov;13(11):1827-32. doi: 10.1093/annonc/mdf300. PMID: 12419758

Prognosis

Primary cutaneous T-cell lymphoma: a review of the most common entities with focus on recent updates.
Saleh JS, Subtil A, Hristov AC
Hum Pathol 2023 Oct;140:75-100. Epub 2023 Oct 4 doi: 10.1016/j.humpath.2023.09.009. PMID: 37802757
Diagnosis and Management of Cutaneous Lymphomas Including Cutaneous T-cell Lymphoma.
Zic JA
Med Clin North Am 2021 Jul;105(4):737-755. doi: 10.1016/j.mcna.2021.04.010. PMID: 34059248
CD30-Positive Lymphoproliferative Disorders.
Nikolaenko L, Zain J, Rosen ST, Querfeld C
Cancer Treat Res 2019;176:249-268. doi: 10.1007/978-3-319-99716-2_12. PMID: 30596222
Cutaneous lymphoma: Kids are not just little people.
Ferenczi K, Makkar HS
Clin Dermatol 2016 Nov-Dec;34(6):749-759. Epub 2016 Jul 10 doi: 10.1016/j.clindermatol.2016.07.010. PMID: 27968935
Anaplastic large-cell lymphoma, T-/null-cell type.
Jacobsen E
Oncologist 2006 Jul-Aug;11(7):831-40. doi: 10.1634/theoncologist.11-7-831. PMID: 16880242

Clinical prediction guides

Distribution and clinical features of lymphomas involving skin in Taiwan.
Wu CL, Chang SW, Lee JY, Chen TY, Chen CC, Chu CB, Medeiros LJ, Chang KC
Kaohsiung J Med Sci 2023 May;39(5):522-532. Epub 2023 Feb 16 doi: 10.1002/kjm2.12659. PMID: 36794661
Primary Cutaneous Small Cell Variant of Anaplastic Large Cell Lymphoma: A Case Series and Review of the Literature.
Magro CM, Momtahen S, Kiuru M
Am J Dermatopathol 2017 Dec;39(12):877-889. doi: 10.1097/DAD.0000000000000908. PMID: 28570392
Anaplastic Variant of Diffuse Large B-cell Lymphoma Displays Intricate Genetic Alterations and Distinct Biological Features.
Li M, Liu Y, Wang Y, Chen G, Chen Q, Xiao H, Liu F, Qi C, Yu Z, Li X, Fan L, Guo Y, Yan Q, Guo S, Wang Z
Am J Surg Pathol 2017 Oct;41(10):1322-1332. doi: 10.1097/PAS.0000000000000836. PMID: 28319526
Primary Cutaneous Anaplastic Large-Cell Lymphoma With 6p25.3 Rearrangement in a Cardiac Transplant Recipient: A Case Report and Review of the Literature.
Olson LC, Cheng E, Mathew S, Torres-Quinones M, Magro C
Am J Dermatopathol 2016 Jun;38(6):461-5. doi: 10.1097/DAD.0000000000000505. PMID: 26863058
CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features.
Stein H, Foss HD, Dürkop H, Marafioti T, Delsol G, Pulford K, Pileri S, Falini B
Blood 2000 Dec 1;96(12):3681-95. PMID: 11090048

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...