U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Distantly Metastatic Malignant Neoplasm

MedGen UID:
234203
•Concept ID:
C1333309
•
Neoplastic Process

Definition

A malignant tumor that has spread from its original (primary) site of growth to another site distant from the primary site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDistantly Metastatic Malignant Neoplasm

Professional guidelines

PubMed

Prognostic factors and the role of locoregional treatment in patients with distantly metastatic hypopharyngeal cancer: a retrospective cohort study based on SEER database.
Wang W, Zheng H, Yu L, Zhang L
Ann Palliat Med 2022 Jun;11(6):1925-1939. Epub 2022 Jan 17 doi: 10.21037/apm-21-2953. PMID: 35073716
Integration of Stereotactic Body Radiation Therapy into the Multidisciplinary Management of Pancreatic Cancer.
Rosati LM, Kumar R, Herman JM
Semin Radiat Oncol 2017 Jul;27(3):256-267. Epub 2017 Feb 20 doi: 10.1016/j.semradonc.2017.02.005. PMID: 28577833
Multidisciplinary approach for the treatment of gastric cancer.
Quiros RM, Desai DC
Minerva Gastroenterol Dietol 2011 Mar;57(1):53-68. PMID: 21372770

Recent clinical studies

Etiology

New revisions and current issues in the eighth edition of the TNM classification for non-small cell lung cancer.
Hattori A, Takamochi K, Oh S, Suzuki K
Jpn J Clin Oncol 2019 Jan 1;49(1):3-11. doi: 10.1093/jjco/hyy142. PMID: 30277521
BRAFV600E mutation does not mean distant metastasis in thyroid papillary carcinomas.
Sancisi V, Nicoli D, Ragazzi M, Piana S, Ciarrocchi A
J Clin Endocrinol Metab 2012 Sep;97(9):E1745-9. Epub 2012 Jun 27 doi: 10.1210/jc.2012-1526. PMID: 22740704
Radiology of colorectal cancer.
Pijl ME, Chaoui AS, Wahl RL, van Oostayen JA
Eur J Cancer 2002 May;38(7):887-98. doi: 10.1016/s0959-8049(02)00052-7. PMID: 11978513
Clear cell odontogenic carcinoma. A clinicopathologic analysis.
Eversole LR, Duffey DC, Powell NB
Arch Otolaryngol Head Neck Surg 1995 Jun;121(6):685-9. doi: 10.1001/archotol.1995.01890060083017. PMID: 7772324
Detection of human papillomavirus DNA in anogenital neoplasias.
Zachow KR, Ostrow RS, Bender M, Watts S, Okagaki T, Pass F, Faras AJ
Nature 1982 Dec 23;300(5894):771-3. doi: 10.1038/300771a0. PMID: 6294530

Diagnosis

NLRP3 inflammasome-mediated cytokine production and pyroptosis cell death in breast cancer.
Faria SS, Costantini S, de Lima VCC, de Andrade VP, Rialland M, Cedric R, Budillon A, Magalhães KG
J Biomed Sci 2021 Apr 12;28(1):26. doi: 10.1186/s12929-021-00724-8. PMID: 33840390Free PMC Article
Choriocarcinoma with pulmonary and cerebral metastases.
Sierra-Bergua B, Sánchez-Marteles M, Cabrerizo-García JL, Sanjoaquin-Conde I
Singapore Med J 2008 Oct;49(10):e286-8. PMID: 18946601
Combined treatment for limited small cell lung cancer.
Komaki R
Semin Oncol 2003 Aug;30(4 Suppl 9):56-70. doi: 10.1016/s0093-7754(03)00270-7. PMID: 12908137
Radiology of colorectal cancer.
Pijl ME, Chaoui AS, Wahl RL, van Oostayen JA
Eur J Cancer 2002 May;38(7):887-98. doi: 10.1016/s0959-8049(02)00052-7. PMID: 11978513
Detection of human papillomavirus DNA in anogenital neoplasias.
Zachow KR, Ostrow RS, Bender M, Watts S, Okagaki T, Pass F, Faras AJ
Nature 1982 Dec 23;300(5894):771-3. doi: 10.1038/300771a0. PMID: 6294530

Therapy

A case report of abdominal metastatic dermatofibrosarcoma protuberans misdiagnosed as gastrointestinal stromal tumor.
Deng M, Liu Q, Ren L, Yuan W, Xu C, Hou Y
Diagn Pathol 2024 Feb 22;19(1):41. doi: 10.1186/s13000-023-01430-9. PMID: 38388419Free PMC Article
Consolidative Radiotherapy for Limited Metastatic Non-Small-Cell Lung Cancer: A Phase 2 Randomized Clinical Trial.
Iyengar P, Wardak Z, Gerber DE, Tumati V, Ahn C, Hughes RS, Dowell JE, Cheedella N, Nedzi L, Westover KD, Pulipparacharuvil S, Choy H, Timmerman RD
JAMA Oncol 2018 Jan 11;4(1):e173501. doi: 10.1001/jamaoncol.2017.3501. PMID: 28973074Free PMC Article
Choriocarcinoma with pulmonary and cerebral metastases.
Sierra-Bergua B, Sánchez-Marteles M, Cabrerizo-García JL, Sanjoaquin-Conde I
Singapore Med J 2008 Oct;49(10):e286-8. PMID: 18946601
Ewing sarcoma: favourable results with combined modality therapy and conservative use of radiotherapy.
Zogopoulos G, Teskey L, Sung L, Dix D, Grant R, Greenberg ML, Weitzman S
Pediatr Blood Cancer 2004 Jul;43(1):35-9. doi: 10.1002/pbc.20037. PMID: 15170887
Palliative operations for patients with unresectable endocrine neoplasia.
Zogakis TG, Norton JA
Surg Clin North Am 1995 Jun;75(3):525-38. doi: 10.1016/s0039-6109(16)46638-7. PMID: 7538230

Prognosis

New revisions and current issues in the eighth edition of the TNM classification for non-small cell lung cancer.
Hattori A, Takamochi K, Oh S, Suzuki K
Jpn J Clin Oncol 2019 Jan 1;49(1):3-11. doi: 10.1093/jjco/hyy142. PMID: 30277521
BRAFV600E mutation does not mean distant metastasis in thyroid papillary carcinomas.
Sancisi V, Nicoli D, Ragazzi M, Piana S, Ciarrocchi A
J Clin Endocrinol Metab 2012 Sep;97(9):E1745-9. Epub 2012 Jun 27 doi: 10.1210/jc.2012-1526. PMID: 22740704
Radiology of colorectal cancer.
Pijl ME, Chaoui AS, Wahl RL, van Oostayen JA
Eur J Cancer 2002 May;38(7):887-98. doi: 10.1016/s0959-8049(02)00052-7. PMID: 11978513
Clear cell odontogenic carcinoma. A clinicopathologic analysis.
Eversole LR, Duffey DC, Powell NB
Arch Otolaryngol Head Neck Surg 1995 Jun;121(6):685-9. doi: 10.1001/archotol.1995.01890060083017. PMID: 7772324
Palliative operations for patients with unresectable endocrine neoplasia.
Zogakis TG, Norton JA
Surg Clin North Am 1995 Jun;75(3):525-38. doi: 10.1016/s0039-6109(16)46638-7. PMID: 7538230

Clinical prediction guides

Development and testing of a random forest-based machine learning model for predicting events among breast cancer patients with a poor response to neoadjuvant chemotherapy.
Jin Y, Lan A, Dai Y, Jiang L, Liu S
Eur J Med Res 2023 Sep 30;28(1):394. doi: 10.1186/s40001-023-01361-7. PMID: 37777809Free PMC Article
Efficacy and Safety of Tyrosine Kinase Inhibitors in Patients with Metastatic Pheochromocytomas/Paragangliomas.
Zhou Y, Cui Y, Zhang D, Tong A
J Clin Endocrinol Metab 2023 Feb 15;108(3):755-766. doi: 10.1210/clinem/dgac657. PMID: 36383456
BRAFV600E mutation does not mean distant metastasis in thyroid papillary carcinomas.
Sancisi V, Nicoli D, Ragazzi M, Piana S, Ciarrocchi A
J Clin Endocrinol Metab 2012 Sep;97(9):E1745-9. Epub 2012 Jun 27 doi: 10.1210/jc.2012-1526. PMID: 22740704
Prognostic implications of prostate-specific antigen in patients with locally advanced prostate cancer treated with high energy neutron beam therapy: preliminary results.
Saroja KR, Oesterling JE, Hendrickson F, Cohen L, Mansell J
Urology 1993 Jun;41(6):540-7. doi: 10.1016/0090-4295(93)90101-f. PMID: 7685957
The value of morphological prognostic criteria in the assessment of renal cell carcinoma.
Jonas D, Thoma B, Beckert H, Weber W
Urol Int 1985;40(3):148-54. doi: 10.1159/000281070. PMID: 4012909

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...