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Stage IV Major Salivary Gland Carcinoma with Metastasis

MedGen UID:
234887
•Concept ID:
C1336424
•
Neoplastic Process
Synonyms: Stage IV Carcinoma of Major Salivary Gland with Metastasis; Stage IV Carcinoma of the Major Salivary Gland with Metastasis

Definition

Stage IV carcinoma of the major salivary glands with regional lymph nodes and/or distant metastases. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage IV Major Salivary Gland Carcinoma with Metastasis

Professional guidelines

PubMed

Management and outcome of patients with malignant salivary gland tumors.
Bell RB, Dierks EJ, Homer L, Potter BE
J Oral Maxillofac Surg 2005 Jul;63(7):917-28. doi: 10.1016/j.joms.2005.03.006. PMID: 16003616

Recent clinical studies

Etiology

Prognostic factors for sublingual gland carcinoma: a population-based Surveillance, Epidemiology and End Results database study.
Qin G, Wu L, Li C, Zhang Q, An Z, Qin J
J Int Med Res 2023 Nov;51(11):3000605231187940. doi: 10.1177/03000605231187940. PMID: 37944187Free PMC Article
Survival and prognostic factors of salivary gland malignant mixed tumor-not otherwise specified: A population-based analysis.
Soffer JM, Nassif SJ, Von Plato M, Chisholm J, O'Leary MA
Am J Otolaryngol 2021 Nov-Dec;42(6):103135. Epub 2021 Jun 19 doi: 10.1016/j.amjoto.2021.103135. PMID: 34171696
Lymphoepithelial Carcinoma of Salivary Gland EBV-association in Endemic versus Non-Endemic Patients: A Report of 16 Cases.
Whaley RD, Carlos R, Bishop JA, Rooper L, Thompson LDR
Head Neck Pathol 2020 Dec;14(4):1001-1012. Epub 2020 May 27 doi: 10.1007/s12105-020-01172-w. PMID: 32462279Free PMC Article
Prognostic Factors in Myoepithelial Carcinoma of the Major Salivary Glands.
Xiao CC, Baker AB, White-Gilbertson SJ, Day TA
Otolaryngol Head Neck Surg 2016 Jun;154(6):1047-53. Epub 2016 Apr 5 doi: 10.1177/0194599816637605. PMID: 27048677
Pattern of recurrent disease in major salivary gland adenocystic carcinoma.
Hirvonen K, Bäck L, Saarilahti K, Leivo I, Hagström J, Mäkitie AA
Virchows Arch 2015 Jul;467(1):19-25. Epub 2015 Apr 3 doi: 10.1007/s00428-015-1760-5. PMID: 25838077

Diagnosis

THE STUDY OF PROGNOSTIC VALUE OF microRNAs (miR-10b AND -155) AND CDKN2A/P16INK4A IN ORAL SQUAMOUS CELL CARCINOMA.
Kravets О, Burtyn O, Borikun T, Rossylna O
Exp Oncol 2023 Oct 11;45(2):187-194. doi: 10.15407/exp-oncology.2023.02.187. PMID: 37824773
Survival and prognostic factors of salivary gland malignant mixed tumor-not otherwise specified: A population-based analysis.
Soffer JM, Nassif SJ, Von Plato M, Chisholm J, O'Leary MA
Am J Otolaryngol 2021 Nov-Dec;42(6):103135. Epub 2021 Jun 19 doi: 10.1016/j.amjoto.2021.103135. PMID: 34171696
Lymphoepithelial Carcinoma of Salivary Gland EBV-association in Endemic versus Non-Endemic Patients: A Report of 16 Cases.
Whaley RD, Carlos R, Bishop JA, Rooper L, Thompson LDR
Head Neck Pathol 2020 Dec;14(4):1001-1012. Epub 2020 May 27 doi: 10.1007/s12105-020-01172-w. PMID: 32462279Free PMC Article
Major salivary gland diseases. Multicentre study.
Fiorella R, Di Nicola V, Fiorella ML, Spinelli DA, Coppola F, Luperto P, Madami L
Acta Otorhinolaryngol Ital 2005 Jun;25(3):182-90. PMID: 16450775Free PMC Article
Malignant salivary gland tumors in Quito, Ecuador.
Pacheco-Ojeda L, Domeisen H, Narvaez M, Tixi R, Vivar N
ORL J Otorhinolaryngol Relat Spec 2000 Nov-Dec;62(6):296-302. doi: 10.1159/000027772. PMID: 11054011

Therapy

Conservative neck dissection in oral cancer patients: a 5 year retrospective study in Malaysia.
Balasundram S, Mustafa WM, Ip J, Adnan TH, Supramaniam P
Asian Pac J Cancer Prev 2012;13(8):4045-50. doi: 10.7314/apjcp.2012.13.8.4045. PMID: 23098514

Prognosis

Prognostic factors for sublingual gland carcinoma: a population-based Surveillance, Epidemiology and End Results database study.
Qin G, Wu L, Li C, Zhang Q, An Z, Qin J
J Int Med Res 2023 Nov;51(11):3000605231187940. doi: 10.1177/03000605231187940. PMID: 37944187Free PMC Article
Survival and prognostic factors of salivary gland malignant mixed tumor-not otherwise specified: A population-based analysis.
Soffer JM, Nassif SJ, Von Plato M, Chisholm J, O'Leary MA
Am J Otolaryngol 2021 Nov-Dec;42(6):103135. Epub 2021 Jun 19 doi: 10.1016/j.amjoto.2021.103135. PMID: 34171696
Prognostic Factors in Myoepithelial Carcinoma of the Major Salivary Glands.
Xiao CC, Baker AB, White-Gilbertson SJ, Day TA
Otolaryngol Head Neck Surg 2016 Jun;154(6):1047-53. Epub 2016 Apr 5 doi: 10.1177/0194599816637605. PMID: 27048677
Pattern of recurrent disease in major salivary gland adenocystic carcinoma.
Hirvonen K, Bäck L, Saarilahti K, Leivo I, Hagström J, Mäkitie AA
Virchows Arch 2015 Jul;467(1):19-25. Epub 2015 Apr 3 doi: 10.1007/s00428-015-1760-5. PMID: 25838077
Management and outcome of patients with malignant salivary gland tumors.
Bell RB, Dierks EJ, Homer L, Potter BE
J Oral Maxillofac Surg 2005 Jul;63(7):917-28. doi: 10.1016/j.joms.2005.03.006. PMID: 16003616

Clinical prediction guides

Prognostic factors for sublingual gland carcinoma: a population-based Surveillance, Epidemiology and End Results database study.
Qin G, Wu L, Li C, Zhang Q, An Z, Qin J
J Int Med Res 2023 Nov;51(11):3000605231187940. doi: 10.1177/03000605231187940. PMID: 37944187Free PMC Article
Anatomic extent of lymph node metastases as an independent prognosticator in node-positive major salivary gland carcinoma: A study of the US SEER database and a Chinese multicenter cohort.
Shi X, Liu XK, An CM, Wei WJ, Tao Y, Ji Y, Zhang Y, Han W, Xue JC, Huang NS, Ma B, Zhang CP, Yang X, Wang KJ, Liu QJ, Liu Y, Wang Y, Lei BW, Yu PC, Hu JQ, Lu ZW, Hu WP, Tian YX, Wang YL, Ji QH
Eur J Surg Oncol 2019 Nov;45(11):2143-2150. Epub 2019 Jun 21 doi: 10.1016/j.ejso.2019.06.029. PMID: 31253544
Prognostic Factors in Myoepithelial Carcinoma of the Major Salivary Glands.
Xiao CC, Baker AB, White-Gilbertson SJ, Day TA
Otolaryngol Head Neck Surg 2016 Jun;154(6):1047-53. Epub 2016 Apr 5 doi: 10.1177/0194599816637605. PMID: 27048677
Major salivary gland diseases. Multicentre study.
Fiorella R, Di Nicola V, Fiorella ML, Spinelli DA, Coppola F, Luperto P, Madami L
Acta Otorhinolaryngol Ital 2005 Jun;25(3):182-90. PMID: 16450775Free PMC Article
Management and outcome of patients with malignant salivary gland tumors.
Bell RB, Dierks EJ, Homer L, Potter BE
J Oral Maxillofac Surg 2005 Jul;63(7):917-28. doi: 10.1016/j.joms.2005.03.006. PMID: 16003616

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